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Journal Articles

18-Months Follow-up of the Trial of Imatinib after Ponatinib Induction (TIPI) in the Front-Line Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Setting

Franck E. Nicolini, Aude Charbonnier, Martine Escoffre-Barbe, Eric Jourdan, Gabrielle Roth-Guepin, Marc G. Berger, Shanti Ame, Marion Simonet, Hyacinthe A Johnson-Ansah, Viviane Dubruille, Amandine Charbonnier, Philippe Rousselot, Corentin Orvain, Bertrand Joly, Jean-Christophe Ianotto, Emilie Cayssials, Mathieu Meunier, Anne Parry, Valerie Coiteux, Laurence Legros, Hacene Zerazhi, Gabriel Etienne, Philippe Quittet, Ollivier Legrand, Amelie Penot, Lydia Roy, Charlotte Doublet, Stéphane Morisset, Romaine Mayet, Gwenaëlle Garin, Stéphanie Dulucq, Françoise Huguet
Journal: Blood
Blood (2024) 144 (Supplement 1): 478.
https://doi.org/10.1182/blood-2024-198903
Published: 2024
Journal Articles

A Phase 2 Prospective Study Evaluating Low-Dose Deferasirox in Patients with Low-Risk Myelodysplastic Syndrome Resistant or Relapsing after Erythropoietin Stimulating Agents (LODEFI)

Mathieu Meunier, Sylvain Thepot, Stanislas Nimubona, Mélanie Véloso, Thibaud Lefebvre, Karim Zoubida, Martine Ropert-Bouchet, Frederic Garban, Shanti Ame, Abdesssamia Gandoul, Claire Reynes, Celia Salanoubat, Sébastien Maury, Kamel Laribi, Pirayeh Eftekhari, Jacques Delaunay, Geoffroy Venton, Clemence Santana, Stephane Cheze, Sophie Dimicoli-Salazar, Mathieu Molimard, Valérie Rolland-Neyret, Sandra David-Tchouda, Sophie Park
Journal: Blood
Blood (2024) 144 (Supplement 1): 1826.
https://doi.org/10.1182/blood-2024-198104
Published: 2024
Journal Articles

T rial of Imatinib after Ponatinib Induction (TIPI) in the Front-Line Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Setting. Report of the First Therapeutic Sequence

Franck E. Nicolini, Aude Charbonnier, Martine Escoffre-Barbe, Eric Jourdan, Gabrielle Roth-Guepin, Marc G. Berger, Shanti Amé, Marion Simonet, Hyacinthe A. Johnson-Ansah, Viviane Dubruille, Amandine Charbonnier, Philippe Rousselot, Corentin Orvain, Bertrand Joly, Jean-Christophe Ianotto, Emilie Cayssials, Mathieu Meunier, Anne Parry, Valerie Coiteux, Laurence Legros, Hacene Zerazhi, Gabriel Etienne, Philippe Quittet, Ollivier Legrand, Amelie Penot, Lydia Roy, Ludovic Fouillet, Stéphane Morisset, Isabelle Tigaud, Romaine Mayet, Gwenaëlle Garin, Jérôme Guitton, Stéphanie Dulucq, Françoise Huguet
Journal: Blood
Blood (2023) 142 (Supplement 1): 445.
https://doi.org/10.1182/blood-2023-181571
Published: 2023
Journal Articles

Characteristics, Outcomes, Tfr Rates in Young Adults with Chronic Myeloid Leukemia in the Tyrosine Kinase Inhibitor Era: A French Observational Study

Laurence Legros, Francoise Huguet, Pascale Cony-Makhoul, Irit Touitou, Franck E. Nicolini, Delphine Rea, Marc G. Berger, Madalina Uzunov, Lydia Roy, Martine Escoffre Barbe, Agnes Guerci Bresler, Gabriel Etienne, Elisabeth Daguenet, Amelie Penot, Martine Gardembas Pain, Shanti Ame, Eric Jourdan, Hyacinthe A. Johnson-Ansah, Valerie Coiteux, Antoine Machet, Eric Lippert, Anne Vekoff, Jean Michel Karsenti, Stéphane Morisset, Francois Mahon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1800.
https://doi.org/10.1182/blood-2023-173132
Published: 2023
Journal Articles

Thrombosis with Non-Proliferative Complete Blood Count Indicative of Underlying Myeloproliferative Neoplasm, Sythrom, a Study on Behalf of the FIM Group

Yannick LE Bris, Jean Galtier, Dina Naguib, Mathieu Wemeau, Jean Claude Chomel, Laurence Legros, Yan Beauverd, Lise Willems, Guillaume Denis, Françoise Boyer perrard, Damien Luque-Paz, Kamel Laribi, Mélanie Mercier, Pascale Cony-Makhoul, Olivier Herault, Lydia Roy, Pierre Sujobert, Lenaig Le Clech, Sylvie Tondeur, Gaelle Laboure, Jerome Rey, Guillou Sophie, Cedric Pastoret, Pascaline Etancelin, Suzanne Tavitian, Charles Bescond, Francois Girodon, Shanti Amé, Viviane Dubruille, Eric Lippert, Chloe James, Barbara Burroni, Marc Fouassier, Marie C Béné, Jean Christophe Ianotto
Journal: Blood
Blood (2022) 140 (Supplement 1): 9668–9669.
https://doi.org/10.1182/blood-2022-159928
Published: 2022
Journal Articles

Treatment-Free Remissions in Newly Diagnosed CP CML Patients Treated with the Combination of Nilotinib + Pegylated Interferon Alpha 2a Versus Nilotinib Alone in the National Phase III Petals Trial

Franck E. Nicolini, Gabriel Etienne, Francoise Huguet, Agnès Guerci-Bresler, Aude Charbonnier, Martine Escoffre-Barbe, Viviane Dubruille, Hyacinthe Johnson-Ansah, Laurence Legros, Valerie Coiteux, Pascale Cony-Makhoul, Pascal Lenain, Lydia Roy, Philippe Rousselot, Denis Guyotat, Jean-Christophe Ianotto, Corentin Orvain, Eric Deconinck, Denis Caillot, Pascal Turlure, Stephane Courby, Philippe Quittet, Eric Hermet, Shanti Amé, Simona Lapusan, Stephane Morisset, Francois-Xavier Mahon, Delphine Rea, Stephanie Dulucq
Journal: Blood
Blood (2021) 138 (Supplement 1): 2553.
https://doi.org/10.1182/blood-2021-146412
Published: 2021
Journal Articles

A Phase II Study of the Efficacy and Tolerance of Azacytidine (AZA) in Steroid Dependent/Refractory Systemic Autoimmune and Inflammatory Disorders (SAID) Associated with MDS or CMML (GFM- AZA-SAID -trial)

Arsène Mékinian, Lin-Pierre Zhao, Kristell Desseaux, Rose Rose, Laurent Pascal, Pierre Peterlin, Thibault Comont, Alexandre Maria, Louis Terriou, Maud d'Aveni, Marie-Pierre Gourin, Norbert Vey, Odile bayne Rouzy, Sophie Dimicoli Salazar, Anne Banos, Stefan Wickenhauser, Benoit De Renzis, Eric Durot, Shanti Ame, Laurent Voillat, Fatiha Chermat, Anne Vekhoff, Karine Lemaire, Vincent Jachiet, Sylvie Chevret, Lionel Ades, Olivier Fain, Pierre Fenaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 3697.
https://doi.org/10.1182/blood-2021-150904
Published: 2021
Journal Articles

The Combination of Nilotinib + Pegylated IFN Alpha 2a Provides Somewhat Higher Cumulative Incidence Rates of MR4.5 at M36 Versus Nilotinib Alone in Newly Diagnosed CP CML Patients. Updated Results of the Petals Phase III National Study.

Franck E Nicolini, MD PhD, Gabriel Etienne, MD PhD, Francoise Huguet, MD, Agnès Guerci-Bresler, MD PhD, Aude Charbonnier, MD PhD, Martine Escoffre-Barbe, MD, Viviane Dubruille, MD, Hyacinthe Johnson-Ansah, MD, Laurence Legros, MD PhD, Valerie Coiteux, MD, Pascale Cony-Makhoul, MD, Pascal Lenain, MD, Lydia Roy, MD, Philippe Rousselot, MD PhD, Denis Guyotat, MD PhD, Jean-Christophe Ianotto, MD PhD, Martine Gardembas, MD, Eric Deconinck, MD PhD, Fabrice Larosa, MD, Denis Caillot, MD, Pascal Turlure, MD, Stephane Courby, MD, Philippe Quittet, MD, Eric Hermet, MD, Shanti Ame, MD, Simona Lapusan, MD, Alexandre Deloire, CRA, Stephane Morisset, BioStat, Madeleine Etienne, CRA, Delphine Rea, MD, Stephanie Dulucq, PharmD, PhD, Francois-Xavier Mahon, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 494.
https://doi.org/10.1182/blood-2019-123674
Published: 2019
Journal Articles

First-Line Second Generation Tyrosine Kinase Inhibitors in Newly Diagnosed Accelerated Phase Chronic Myeloid Leukemia Patients.

Marie Balsat, MD, Vincent Alcazer, MD, Gabriel Etienne, MD PhD, Gaelle Fossard, MD, Francoise Huguet, MD, Marc G. Berger, MD PhD, Emilie Cayssials, MD, Aude Charbonnier, MD, Martine Escoffre-Barbe, MD, Hyacinthe Johnson-Ansah, MD, Viviane Dubruille, MD, Laurence Legros, MD PhD, Lydia Roy, MD, Alain Jacques Delmer, MD, Jean-Christophe Ianotto, MD PhD, Martine Gardembas, MD, Fabrice Larosa, Stephane Courby, MD, Shanti Ame, MD, Stephane Morisset, Stat, Francois-Xavier Mahon, MD PhD, Delphine Rea, MD, Franck Emmanuel Nicolini, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 48.
https://doi.org/10.1182/blood-2018-99-113058
Published: 2018
Journal Articles

A Randomized Phase II Study of Azacitidine (AZA) Alone or with Lenalidomide (LEN), Valproic Acid (VPA) or Idarubicin (IDA) in Higher-Risk MDS: Gfm's 'pick a Winner' Trial

Lionel Ades, MD PhD, Agnès Guerci, Kamel Laribi, MD, Pierre Peterlin, Norbert Vey, MD PhD, Sylvain Thepot, MD, Stefan Wickenhauser, Hacene Zerazhi, Aspasia Stamatoullas, MD, Eric Wattel, MD PhD, Christian Recher, MD PhD, Andrea Toma, MD PhD, Krimo Bouabdallah, MD, Thorsten Braun, MD PhD, Odile Beyne-Rauzy, Berengere Gruson, MD, Stephane Cheze, Sophie Park, MD PhD, Thomas Cluzeau, MDPhD, Stanislas Nimubona, MD, Dominique Bordessoule, MD, Riad Benramdane, Bruno Quesnel, Shanti Ame, MD, Stephane De Botton, MD PhD, Fatiha Chermat, Julie Lejeune, Sylvie Chevret, MD PhD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 467.
https://doi.org/10.1182/blood-2018-99-111756
Published: 2018
Journal Articles

Germline Mutations Occurring Outside the Negatively Charged Amino Acid Stretches of the Exon 9 of Calr : A Predisposition to Hematological Malignancies?

Laurent Miguet, PhD, Carine Gervais, MD, Antoine Ittel, PharmD, Eric Jeandidier, MD, Anne Galoisy, PharmD, Caroline Mayeur-Rousse, MD, Laurie Monier, PharmD, Alice Eischen, PharmD, Laurent Daniel Vallat, MD PhD, Mario Ojeda, MD, Bernard Drenou, MD, Shanti Ame, MD, Raoul Herbrecht, MD, Laurent Mauvieux, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1646.
https://doi.org/10.1182/blood.V130.Suppl_1.1646.1646
Published: 2017
Journal Articles

Nilotinib Versus Nilotinib Combined to Pegylated-Interferon Alfa 2a in First-Line Chronic Phase Chronic Myelogenous Leukemia Patients. Interim Analysis of a Phase III Trial

Franck Emmanuel Nicolini, MD PhD, Gabriel Etienne, MD PhD, Francoise Huguet, MD, Agnes Guerci-Bresler, Aude Charbonnier, MD, Martine Escoffre-Barbe, MD, Viviane Dubruille, MD, Hyacinthe Johnson-Ansah, MD, Laurence Legros, MDPhD, Valerie Coiteux, MD, Pascale Cony-Makhoul, MD PhD, Pascal Lenain, MD, Lydia Roy, MD, Philippe Rousselot, Denis Guyotat, Jean-Christophe Ianotto, MD, Martine Gardembas, MD, Fabrice Larosa, MD, Denis Caillot, MD, Pascal Turlure, MD, Stephane Courby, MD, Philippe Quittet, MD, Eric Hermet, MD, Shanti Ame, MD, Simona Lapusan, MD, Verane Schwiertz, PharmD, Stephane Morisset, Stat, Madeleine Etienne, CRA, Delphine Rea, MD PhD, Stephanie Dulucq, PhD, Francois-Xavier Mahon, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 899.
https://doi.org/10.1182/blood.V130.Suppl_1.899.899
Published: 2017
Journal Articles

Dyserythropoiesis Evaluated By Red Score and Hepcidin/Ferritin Levels Predicts Response to Epoetin Zeta in Lower Risk MDS

Olivier Kosmider, Frederic Maloisel, Bernard Drenou, MD, Nicolas Chapuis, PharmD, PhD, Anne Sophie Alary, Alice Rousseau, Cecile Bouilloux, Sarah Ducamp, PhD, Frederique Verdier, Thibaud Lefebvre, Zoubida Karim, Marie-Christine Jacob, Agathe Debliquis, Agnes Charpentier, Pierre Fenaux, MD PhD, Emmanuel Gyan, MDPhD, Bruno Anglaret, Cecile Leyronnas, Selim Corm, Borhane Slama, MD, Stephane Cheze, Kamel Laribi, Shanti Ame, MD, Christian Rose, MD, Florence Lachenal, Andrea Toma, MD PhD, Gian Matteo Pica, MD, Martin Carre, Frederic Garban, Brigitte Pegourie, MD, Jean-Yves Cahn, Mathieu Meunier, MD, Orianne Wagner Ballon, Olivier Herault, MDPhD, Francois Dreyfus, Valerie Bardet, Michaela Fontenay, MD PhD, Sophie Park, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1705.
https://doi.org/10.1182/blood.V130.Suppl_1.1705.1705
Published: 2017
Journal Articles

Prospective Evaluation of the Effect of Deferasirox on Hematologic Response in Transfusion-Dependent Patients with Low-Risk MDS and Iron Overload: The Rythmex Study

Christian Rose, MD, Olivier Fitoussi, MD, Emmanuel Gyan, MD PhD, Maya Hacini, MD, Shanti Amé, MD, Bernadette Corront, MD, Odile Beyne-Rauzy, MD PhD, Didier Innocent Adiko, MD, Elena-Anca Loppinet, MD, Nadia Ali-Ammar, MD, Eric Wattel, MD PhD, Francois Dreyfus, MD, Stéphane Cheze, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2008.
https://doi.org/10.1182/blood.V128.22.2008.2008
Published: 2016
Journal Articles

Combination of Dasatinib and Peg-Interferon Alpha 2b in Chronic Phase Chronic Myeloid Leukemia (CP-CML) First Line: Preliminary Results of a Phase II Trial, from the French Intergroup of CML (Fi-LMC)

Lydia ROY, MD, Jean-Claude Chomel, PharmD PhD, Joelle Guilhot, PhD, Agnes Guerci-Bresler, MD, Martine Escoffre-Barbe, Stéphane Giraudier, MD PhD, Aude Charbonnier, Viviane Dubruille, MD, Françoise Huguet, Hyacinthe Johnson-Ansah, MD, Pascal Lenain, MD, Shanti Amé, MD, Gabriel Etienne, MD PhD, Franck E. Nicolini, Delphine Rea, MD PhD, Pascale Cony-Makhoul, MD, Stephane Courby, MD, Jean-Christophe Ianotto, MD, Laurence Legros, MD, Martine Delain, MD, Valérie Coiteux, MD, Eric Hermet, MD, Martine Gardembas, MD, Mathieu Molimard, MD PhD, Jean-Michel Cayuela, Marie Thibaud, CRA, Sophie Duranton, PharmD, Francois-Xavier Mahon, MD PhD, Philippe Rousselot, MD PhD Professor, Francois Guilhot, MD
Journal: Blood
Blood (2015) 126 (23): 134.
https://doi.org/10.1182/blood.V126.23.134.134
Published: 2015
Journal Articles

Ponatinib for Chronic Phase (CP) CML Failing Two or More Tyrosine Kinase Inhibitors (TKI) or Harboring a T315I Mutation in the Real Life: Pearl Observational Study

Franck E. Nicolini, MD PhD, Mael Heiblig, MD, Stéphane Morisset, Stat, Denis Caillot, Valérie Coiteux, MD, Aude Charbonnier, MD, Françoise Huguet, MD, Viviane Dubruille, MD, Gabriel Etienne, MD PhD, Pascal Lenain, MD, Francois Guilhot, MD, Laurence Legros, MD, Philippe Rousselot, MD PhD, Shanti Amé, MD, Rémy DeFrance, MD, Jeremy Ruby, CRA, Francois-Xavier Mahon, MD PhD Professor, Delphine Rea
Journal: Blood
Blood (2015) 126 (23): 4039.
https://doi.org/10.1182/blood.V126.23.4039.4039
Published: 2015
Journal Articles

Pegylated Interferon-Alpha 2a in Combination with Nilotinib As First-Line Therapy in Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (Nilopeg trial). Four-Year Follow-up Results

Franck E. Nicolini, MD PhD, Gabriel Etienne, MD PhD, Viviane Dubruille, MD, Lydia Roy, MD, Françoise Huguet, MD, Laurence Legros, MD, Stéphane Giraudier, MD PhD, Valérie Coiteux, MD, Agnes Guerci-Bresler, MD, Pascal Lenain, MD, Delphine Rea, Shanti Amé, MD, Pascale Cony-Makhoul, MD, Martine Gardembas, MD, Eric Hermet, MD, Philippe Rousselot, MD PhD, Marie-Claude Gagnieu, PharmD, PhD, Stéphane Morisset, Stat, Christine Pivot, PharmD, Madeleine Etienne, CRA, Francois Guilhot, MD, Stéphanie Dulucq, PharmD, PhD, Francois-Xavier Mahon, MD PhD Professor
Journal: Blood
Blood (2015) 126 (23): 1578.
https://doi.org/10.1182/blood.V126.23.1578.1578
Published: 2015
Journal Articles

The Revised IPSS (IPSS-R) Predicts Response To Erythropoietic Stimulating agents (ESA) In Pts With Classical IPSS Low Or Intermediate-1 (int 1)- MDS: A Joint Retrospective Study Of The GFM, Düsseldorf Registry and Fism

Valeria Santini, Jennifer Schemenau, MD, Alessandro Levis, Enrico Balleari, MD, Rosa Sapena, Lionel Ades, Agnès Guerci, Odile Beyne-Rauzy, MD, PhD, Marie Pierre Gourin, Stéphane Cheze, Aspasia Stamatoullas, MD, Alessandro Sanna, MD, Daniela Gioia, Giani Cametti, MD, Dario Ferrero, MD, Emmanuel Raffoux, Christian Rose, MD, Poloni Antonella, MD, Thomas Prebet, MD, PhD, Shanti Ame, MD, Laurence Legros, MD, PhD, Pierre Fenaux, MD, PhD, Ulrich Germing, MD, Francois Dreyfus, MD, Sophie Park
Journal: Blood
Blood (2013) 122 (21): 2761.
https://doi.org/10.1182/blood.V122.21.2761.2761
Published: 2013
Journal Articles

Pegylated Interferon-α 2a in Combination to Nilotinib As First Line Therapy in Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia Provides High Rates of MR 4.5 . Preliminary Results of a Phase II Study.

Franck E. Nicolini, MD, PhD, Gabriel Etienne, MD, PhD, Viviane Dubruille, MD, Lydia Roy, MD, Françoise Huguet, Laurence Legros, MD, PhD, Stephane Giraudier, MD, PhD, Valérie Coiteux, MD, Agnès Guerci-Bresler, MD, Pascal Lenain, MD, Delphine Rea, MD, PhD, Shanti Ame, MD, Pascale Cony-Makhoul, MD, Martine Gardembas, MD, Eric Hermet, MD, Philippe Rousselot, MD, PhD, Marie-Claude Gagnieu, PharmD, PhD, Stephane Morisset, Stat., Christine Pivot, Pharm., Madeleine Etienne, CRA, François Guilhot, MD, Stephanie Dulucq, MD, Francois-Xavier Mahon, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 166.
https://doi.org/10.1182/blood.V120.21.166.166
Published: 2012
Journal Articles

Evaluation of Leukemic Stem Cell Persistence in Chronic Myeloid Leukemia (CML) Patients in Complete Molecular Remission Induced by First Line TKI Therapies

Jean-Claude Chomel, PharmD, PhD, Marie Laure Bonnet, Nathalie Sorel, PhD, Ivan Sloma, PharmD, PhD, Alexis Proust, Annelise Bennaceur-Griscelli, MD, PhD, Delphine Rea, MD, PhD, Madalina Uzunov, M.D., Laurence Legros, MD, PhD, Shanti Ame, MD, Anne Marfaing-Koka, Agnès Guerci, MD, Philippe Rousselot, MD, PhD, Ali G Turhan, M.D., PhD
Journal: Blood
Blood (2012) 120 (21): 3726.
https://doi.org/10.1182/blood.V120.21.3726.3726
Published: 2012