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Bruno Quesnel
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Journal Articles

Long Term Follow-up and Combined Phase 2 Results of Eprenetapopt (APR-246) and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

David A. Sallman, Rami S. Komrokji, Amy E. DeZern, Marie Sebert, Guillermo Garcia-Manero, Ramy Rahmé, David P. Steensma, Jacqueline Lehmann che, Gail J. Roboz, Isabelle Madelaine, Mikkael A. Sekeres, Pierre Peterlin, Kendra Sweet, Odile Beyne Rauzy, Andrew T. Kuykendall, Christian Recher, Amy F McLemore, Aspasia Stamatoullas, Ling Zhang, Lise Willems, Qianxing Mo, Emmanuel Raffoux, Lisa Nardelli, Celine Berthon, Najla Al Ali, Bruno Quesnel, Eric Padron, Greg Korbel, Eyal C. Attar, Hagop Kantarjian, Alan F. List, Lionel Ades, Jeffrey E. Lancet, Pierre Fenaux, Thomas Cluzeau
Journal: Blood
Blood (2021) 138 (Supplement 1): 246.
https://doi.org/10.1182/blood-2021-153286
Published: 2021
Journal Articles

Expanded Access Program: Evaluating Safety of Erythrocytes Encapsulating L-Asparaginase in Combination with Polychemotherapy in Patients Under 55 Years Old with Acute Lymphoblastic Leukaemia (ALL) at Risk to Receive Other Formulations of Asparaginase

Yves Bertrand, Nicolas Boissel, Claudine Schmitt, Alban Villate, Emmanuel Gyan, Bruno Quesnel, Christian Recher, Pauline Simon, Nathalie Cheikh, Marilyne Poirée, Jean Stephan, Cecile Dumesnil, Iman El-Hariry
Journal: Blood
Blood (2021) 138 (Supplement 1): 1214.
https://doi.org/10.1182/blood-2021-147834
Published: 2021
Journal Articles

Ivosidenib Improves Overall Survival Relative to Standard Therapies in Relapsed or Refractory Mutant IDH1 AML: Results from Matched Comparisons to Historical Controls

Peter Paschka, MD, Hervé Dombret, MD, Xavier Thomas, MD PhD, Christian Recher, MD PhD, Sylvain Chantepie, MD, Pau Montesinos Fernandez, MD PhD, Evelyn Acuña-Cruz, MD, Paresh Vyas, MRCP, FRCP, FRCPath, Karl-Anton Kreuzer, MD, Michael Heuser, Klaus H. Metzeler, MD, Michael Dennis, MD, Bruno Quesnel, MD PhD, Mathilde Hunault-Berger, MDPhD, Mohamad Mohty, MD PhD, Arnaud Pigneux, MD PhD, Stephane De Botton, Daniela Weber, MSc, Konstanze Döhner, Gary Milkovich, PharmD, John Reitan, PharmD, Sarah C MacDonald, SD, Deborah Casso, MPH, Michael Storm, MSc, Hua Liu, PhD, Stephanie M. Kapsalis, BS, Eyal C. Attar, MD, Thomas Winkler, MD, Hartmut Döhner, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-136957
Published: 2020
Journal Articles

Mitochondrial Spare Reserve Capacity : A New Predictive Metabolic Biomarker for Aggressiveness of Acute Myeloid Leukemia

Quentin Fovez, Bruno Quesnel, MD PhD, William Laine, Raeeka Khamari, Celine Berthon, MD PhD, Laure Goursaud, MD, Nicolas Germain, MD, Claude Preudhomme, MD PhD, Philippe Marchetti, MD PhD, Jérôme Kluza, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7.
https://doi.org/10.1182/blood-2020-139510
Published: 2020
Journal Articles

Antimetabolic Cooperativity with l-Asparaginase and Tyrosine Kinase Inhibitor Quizartinib to Eradicate Persistant FLT3-ITD Leukemic Cells

Quentin Fovez, Raeeka Khamari, Anne Trinh, PhD, William Laine, Bruno Quesnel, MD PhD, Philippe Marchetti, MD PhD, Jérôme Kluza, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
https://doi.org/10.1182/blood-2020-139696
Published: 2020
Journal Articles

Inherited transmission of the CSF3R T618I mutational hotspot in familial chronic neutrophilic leukemia

Nicolas Duployez, Christophe Willekens, Isabelle Plo, Alice Marceau-Renaut, Stéphane de Botton, Laurène Fenwarth, Thomas Boyer, Guillemette Huet, Olivier Nibourel, Christian Rose, Brigitte Nelken, Bruno Quesnel, Claude Preudhomme
Journal: Blood
Blood (2019) 134 (26): 2414–2416.
https://doi.org/10.1182/blood.2019003206
Published: 2019
Includes: Supplemental data
Journal Articles

APR-246 Combined with Azacitidine (AZA) in TP53 Mutated Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). a Phase 2 Study By the Groupe Francophone Des Myélodysplasies (GFM)

Thomas Cluzeau, MD PhD, Marie Sebert, MD, Ramy Rahmé, MD, Stefania Cuzzubbo, Anouk Walter-petrich, Jacqueline Lehmann che, Pierre Peterlin, Blandine Beve, Habiba Attalah, Fatiha Chermat, Elsa Miekoutima, Odile Beyne-Rauzy, Christian Recher, MD PhD, Aspasia Stamatoullas, MD, Lise Willems, MD, Emmanuel Raffoux, MD, Céline Berthon, MD PhD, Bruno Quesnel, Antoine Carpentier, David A Sallman, MD, Sylvie Chevret, MD PhD, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 677.
https://doi.org/10.1182/blood-2019-125579
Published: 2019
Journal Articles

MYC Overexpressing Multiple Myeloma Are Dependent on GLS1

Katarina K Jovanovic, PhD, Léa Fléchon, MSc, Mairead Reidy, PhD, Jihye Park, BS, DVM, Xavier Leleu, MD PhD, Irene M. Ghobrial, MD, Thierry Facon, MD, Bruno Quesnel, Salomon Manier, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 853.
https://doi.org/10.1182/blood-2019-128484
Published: 2019
Journal Articles

A Randomized Phase II Study of Azacitidine (AZA) Alone or with Lenalidomide (LEN), Valproic Acid (VPA) or Idarubicin (IDA) in Higher-Risk MDS: Gfm's 'pick a Winner' Trial

Lionel Ades, MD PhD, Agnès Guerci, Kamel Laribi, MD, Pierre Peterlin, Norbert Vey, MD PhD, Sylvain Thepot, MD, Stefan Wickenhauser, Hacene Zerazhi, Aspasia Stamatoullas, MD, Eric Wattel, MD PhD, Christian Recher, MD PhD, Andrea Toma, MD PhD, Krimo Bouabdallah, MD, Thorsten Braun, MD PhD, Odile Beyne-Rauzy, Berengere Gruson, MD, Stephane Cheze, Sophie Park, MD PhD, Thomas Cluzeau, MDPhD, Stanislas Nimubona, MD, Dominique Bordessoule, MD, Riad Benramdane, Bruno Quesnel, Shanti Ame, MD, Stephane De Botton, MD PhD, Fatiha Chermat, Julie Lejeune, Sylvie Chevret, MD PhD, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 467.
https://doi.org/10.1182/blood-2018-99-111756
Published: 2018
Journal Articles

The Medalist Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept to Treat Anemia in Patients with Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions

Pierre Fenaux, MD PhD, Uwe Platzbecker, Ghulam J. Mufti, Guillermo Garcia-Manero, MD, Rena Buckstein, MD FRCPC, Valeria Santini, María Díez-Campelo, Carlo Finelli, MD, Mario Cazzola, Osman Ilhan, MD, Mikkael A. Sekeres, MD MS, José F. Falantes, Beatriz Arrizabalaga, MD PhD, Flavia Salvi, Valentina Giai, Paresh Vyas, David Bowen, MD PhD, Dominik Selleslag, MD, Amy E. DeZern, MD, Joseph G. Jurcic, MD, Ulrich Germing, MD, Katharina S. Götze, MD, Bruno Quesnel, Odile Beyne-Rauzy, Thomas Cluzeau, MD PhD, Maria Teresa Voso, Dominiek Mazure, Edo Vellenga, Peter L Greenberg, MD, Eva Hellström-Lindberg, MD PhD, Amer M. Zeidan, MBBS, MHS, Abderrahmane Laadem, MD, Aziz Benzohra, Jennie Zhang, Anita Rampersad, Peter G. Linde, Matthew L. Sherman, Rami S. Komrokji, MD, Alan F. List, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1.
https://doi.org/10.1182/blood-2018-99-110805
Published: 2018
Journal Articles

Randomized Phase 2 Trial of Lirilumab (anti-KIR monoclonal antibody, mAb) As Maintenance Treatment in Elderly Patients (pts) with Acute Myeloid Leukemia (AML): Results of the Effikir Trial

Norbert Vey, Pierre-Yves Dumas, MD, Christian Recher, MD PhD, Lauris Gastaud, MD, Bruno Lioure, MD, Claude-Eric Bulabois, MD, Cecile Pautas, Jean-Pierre Marolleau, MD PhD, Stéphane Leprêtre, MD, Emmanuel Raffoux, MD, Xavier Thomas, MD, Yosr Hicheri, Caroline Bonmati, MD, Bruno Quesnel, MD PhD, Philippe Rousselot, Sylvie Castaigne, MD PhD, Eric Jourdan, MD, Jean Valère Malfuson, Gaelle Guillerm, MD, Jean Henri Bouhris, Mario Ojeda, MD, Mathilde Hunault, MD PhD, Norbert Ifrah, MD PhD, Claude Gardin, MD PhD, Andre Delannoy, MD, Lucile Beautier, Carine Paturel, PhD, Pascale Andre, PhD, Robert Zerbib, Claude Preudhomme, PharmD, PhD, Antoine Toubert, MD PhD, Nicolas Dulphy, PhD, Daniel Olive, MD PhD, Arnaud Pigneux, MD, Herve Dombret, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 889.
https://doi.org/10.1182/blood.V130.Suppl_1.889.889
Published: 2017
Journal Articles

Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML

Dorothée Selimoglu-Buet, Bouchra Badaoui, Emmanuel Benayoun, Andréa Toma, Pierre Fenaux, Bruno Quesnel, Gabriel Etienne, Thorsten Braun, Nassera Abermil, Margot Morabito, Nathalie Droin, Eric Solary, Orianne Wagner-Ballon
Journal: Blood
Blood (2017) 130 (6): 832–835.
https://doi.org/10.1182/blood-2017-04-779579
Published: 2017
Journal Articles

De Novo and Secondary Acute Myeloid Leukemia, Real World Data on Outcomes from the French Nord-Pas-De-Calais Picardie Acute Myeloid Leukemia Observatory

Loïc Renaud, Olivier Nibourel, PharmD, PhD, Celine Berthon, Christophe Roumier, Céline Rodriguez, Cecile Frimat, Catherine Roche-Lestienne, Aline Renneville, MD, Bruno Quesnel, MD PhD, Claude Preudhomme, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4013.
https://doi.org/10.1182/blood.V128.22.4013.4013
Published: 2016
Journal Articles

Correlation Between Bone Marrow Dysplasia and Genomic Profile in De Novo Acute Myeloid Leukemia (AML): A Study By the ALFA Group

Thomas Cluzeau, MDPhD, Orianne Wagner-Ballon, Thomas Boyer, Estelle Guerin, Emmanuel Benayoun, Daniel Lusina, Isabelle Garcia, Claude Gardin, Pierre Fenaux, MD PhD, Cecile Pautas, Bruno Quesnel, MD PhD, Dominique Bordessoule, Christine Terré, Xavier Thomas, MD PhD, Sylvie Castaigne, Aline Renneville, Claude Preudhomme, Herve Dombret, MD
Journal: Blood
Blood (2015) 126 (23): 2568.
https://doi.org/10.1182/blood.V126.23.2568.2568
Published: 2015
Journal Articles

Expanded Access Program of Graspa for Treatment of Patients with Acute Lymphoblastic Leukemia Unable to Receive Other Form of L-Asparaginase - a Status Update (NCT02197650)

Yves Bertrand, MDPhD, Hervé Dombret, Bruno Quesnel, MD PhD, Jean-Louis Stephan, MD, Claudine Schmitt, MD, Severine Lissandre, MD, Maryline Poiree, MD, Christian Recher, MDPhD, Emmanuel Plouvier, MD, Cécile Dumesnil de Maricourt, MD, David Salako, MSc, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4877.
https://doi.org/10.1182/blood.V126.23.4877.4877
Published: 2015
Journal Articles

Characteristic repartition of monocyte subsets as a diagnostic signature of chronic myelomonocytic leukemia

Dorothée Selimoglu-Buet, Orianne Wagner-Ballon, Véronique Saada, Valérie Bardet, Raphaël Itzykson, Laura Bencheikh, Margot Morabito, Elisabeth Met, Camille Debord, Emmanuel Benayoun, Anne-Marie Nloga, Pierre Fenaux, Thorsten Braun, Christophe Willekens, Bruno Quesnel, Lionel Adès, Michaela Fontenay, Philippe Rameau, Nathalie Droin, Serge Koscielny, Eric Solary
Journal: Blood
Blood (2015) 125 (23): 3618–3626.
https://doi.org/10.1182/blood-2015-01-620781
Published: 2015
Includes: Supplemental data
Journal Articles

Molecular Prognostic Factors in Acute Myeloid Leukemia (AML) Patients Receiving First Line Therapy with Azacytidine (AZA)

Judith Desoutter, Julie Gay, MD, Céline Berthon, MD PhD, Lionel Ades, MD, Jean Pierre Marolleau, MD PhD, Sandrine Geffroy, Isabelle Plantier, MD, Marceau Alice, MD, Nathalie Helevaut, Jose Fernandes, MD, Maxime Bemba, MD, Cécile Frimat, Julien Labreuche, Olivier Nibourel, Christophe Roumier, Martin Figeac, Pierre Fenaux, MD PhD, Bruno Quesnel, MD PhD, Aline Renneville, Claude Preudhomme, PharmD, PhD
Journal: Blood
Blood (2014) 124 (21): 482.
https://doi.org/10.1182/blood.V124.21.482.482
Published: 2014
Journal Articles

Epidemiology of Adults AML in Nord-Pas De Calais and Picardy

Christophe Roumier, MD, Céline Rodriguez, Cécile Frimat, Céline Berthon, MD PhD, Carole Delattre, MD, Marc Wetterwald, MD PhD, Jose Fernandes, MD, Agnes Daudignon, Isabelle Plantier, MD, Agnes Charpentier, MD, Stéphane Darre, MD, Bachra Choufi, MD, Laure Stalnikiewicz, MD, Christine Ghevaert, MD, Jean-Pierre Marolleau, MD PhD, Veronique Harrivel, MD, Olivier Nibourel, PhD, Catherine Roche, PhD, Bruno Quesnel, MD PhD, Claude Preudhomme, PharmD, PhD
Journal: Blood
Blood (2014) 124 (21): 2281.
https://doi.org/10.1182/blood.V124.21.2281.2281
Published: 2014
Journal Articles

Inversely to DNMT3A, IDH1/IDH2 Are Good Targets for Monitoring Minimal Residual Disease (MRD) in Acute Myeloid Leukemia (AML): A Pilot Study of the ALFA Group

Houria Debarri, MD, Delphine Lebon, MD, Christophe Roumier, MD, Meyling Cheok, Alice Marceau-Renaut, Olivier Nibourel, Sandrine Geffroy, Nathalie Helevaut, Philippe Rousselot, MD PhD, Jean-Pierre Marolleau, MD, Claude Gardin, Denis Caillot, MD, Martin Figeac, Céline Berthon, Bruno Quesnel, MD PhD, Nicolas Boissel, MD PhD, Sylvie Castaigne, Hervé Dombret, MD PhD, Aline Renneville, Claude Preudhomme
Journal: Blood
Blood (2014) 124 (21): 2327.
https://doi.org/10.1182/blood.V124.21.2327.2327
Published: 2014
Journal Articles

Multiclonal Diagnosis and MRD Follow-up in ALL with HTS Coupled with a Bioinformatic Analysis

Nathalie Grardel, Mikaël Salson, Aurélie Caillault, Marc Duez, Céline Villenet, Christophe Roumier, Martin Figeac, Brigitte Nelken, Bruno Quesnel, MD PhD, Claude Preudhomme, PharmD, PhD, Mathieu Giraud
Journal: Blood
Blood (2014) 124 (21): 1083.
https://doi.org/10.1182/blood.V124.21.1083.1083
Published: 2014