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Isabelle Madelaine
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Journal Articles

JAK Inhibition Results in Aggressive Cutaneous Squamous Cell Carcinoma through MAPK Pathway Activation and Shapes the Tumor Immune Microenvironment to Create Novel Therapeutic Opportunities

Helene Pasquer, Valeria Bisio, Antoine Forget, Maxime Battistella, Barouyr Baroudjian, Raphael Marie, Emmanuelle Latour, Cecile Culeux, Lea Pelissier, Blandine Roux, Khansa Saadallah, Matthieu Duchmann, Thierry Tchenio, Abdellah Tebani, Amandine Gouverneur, Fanelie Jouenne, Jerome Lambert, Isabelle Madelaine, Lionel Ades, Emmanuel Raffoux, Pernelle Noize, Bruno Cassinat, Soumeya Bekri, Juliette Soret-Dulphy, Samia Mourah, Camille Lobry, Alexandre Puissant, Jean-Jacques Kiladjian, Nicolas Dulphy, Celeste Lebbe, Lina Benajiba
Journal: Blood
Blood (2024) 144 (Supplement 1): 4513.
https://doi.org/10.1182/blood-2024-205839
Published: 2024
Journal Articles

Characteristics and Outcome Determinants in Children, Adolescents and Young Adults Who Failed Tisagenlecleucel for B-Cell Acute Lymphoblastic Leukemia

Nicolas Lecornec, Florence Rabian, Marie-Emilie Dourthe, Florian Chevillon, Karima Yakouben, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Rathana Kim, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, André Baruchel, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1433.
https://doi.org/10.1182/blood-2024-209895
Published: 2024
Journal Articles

Failure and out of Specification Manufacturing of Autologous CAR-T Cells Could be Associated with a High Concentration of Total Nucleated Cells, CD3 + Cells and Neutrophils in the Apheresis Product

Guillaume Cohet, Cedrik NGO-Chin, Nadia Douki, Marion Desniaux, Stellie Cornu, Justine Nasone, Audrey Cras, Lionel Faivre, Nathalie Parquet, Anne Brignier, Dehbia Menouche, Emmanuelle Lesprit, Nabih Azar, Ramdane Belhocine, Isabelle Madelaine, Romain de JORNA, Jerome Larghero, Miryam Mebarki
Journal: Blood
Blood (2023) 142 (Supplement 1): 3520.
https://doi.org/10.1182/blood-2023-174865
Published: 2023
Journal Articles

Low Disease Burden Pre-CAR-T Cell Therapy for Children and AYA with B-ALL Is Associated with an Impaired Outcome When Obtained through Intensification of the Bridging Therapy

Nicolas Lecornec, Marie-Emilie Dourthe, Florence Rabian, Karima Yakouben, Florian Chevillon, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, Nicolas Boissel, André Baruchel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2134.
https://doi.org/10.1182/blood-2023-175045
Published: 2023
Journal Articles

Long Term Follow-up and Combined Phase 2 Results of Eprenetapopt (APR-246) and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

David A. Sallman, Rami S. Komrokji, Amy E. DeZern, Marie Sebert, Guillermo Garcia-Manero, Ramy Rahmé, David P. Steensma, Jacqueline Lehmann che, Gail J. Roboz, Isabelle Madelaine, Mikkael A. Sekeres, Pierre Peterlin, Kendra Sweet, Odile Beyne Rauzy, Andrew T. Kuykendall, Christian Recher, Amy F McLemore, Aspasia Stamatoullas, Ling Zhang, Lise Willems, Qianxing Mo, Emmanuel Raffoux, Lisa Nardelli, Celine Berthon, Najla Al Ali, Bruno Quesnel, Eric Padron, Greg Korbel, Eyal C. Attar, Hagop Kantarjian, Alan F. List, Lionel Ades, Jeffrey E. Lancet, Pierre Fenaux, Thomas Cluzeau
Journal: Blood
Blood (2021) 138 (Supplement 1): 246.
https://doi.org/10.1182/blood-2021-153286
Published: 2021
Journal Articles

Lenalidomide Exposure at Time of CAR T-Cells Expansion Enhances Response of Refractory/Relapsed Aggressive Large B-Cell Lymphomas

Jean Lemoine, Florence Morin, Roberta Di Blasi, Laetitia Vercellino, Alexis Cuffel, Naoufal Benlachgar, Jerome Larghero, Isabelle Madelaine, Julien Calvani, Veronique Meignin, Sophie Caillat-Zucman, Sylvie Chevret, Catherine Thieblemont
Journal: Blood
Blood (2021) 138 (Supplement 1): 1433.
https://doi.org/10.1182/blood-2021-151109
Published: 2021
Journal Articles

Safety and Efficacy of Tisagenlecleucel (CTL019) in B-Cell Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults: The French Experience

Marie-Emilie Dourthe, Florence Rabian, MD, Karima Yakouben, MD, Aurélie Cabannes, MD, Florian Chevillon, MD, Delphine Chaillou, Nathalie Dhedin, MD, Emmanuelle Lesprit, MD, Jerome Naudin, MD, Julie Roupret-Serzec, PharmD, Nathalie Parquet, MD, Anne Brignier, MD, Valérie Guérin, MD, Elodie Lainey, PhD, Aurélie Caye-Eude, PharmD, Helene Cavé, PharmD, PhD, Emmanuelle Clappier, PhD PharmD, Stéphanie Mathis, PharmD, Sophie Caillat-Zucman, MD PhD, Elie Azoulay, MD PhD, Jean-Hugues Dalle, MD PhD, Isabelle Madelaine, PharmD, Jerome Larghero, PharmD, PhD, Nicolas Boissel, MD PhD, André Baruchel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3876.
https://doi.org/10.1182/blood-2019-131123
Published: 2019