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Journal Articles

Characteristics and Outcome Determinants in Children, Adolescents and Young Adults Who Failed Tisagenlecleucel for B-Cell Acute Lymphoblastic Leukemia

Nicolas Lecornec, Florence Rabian, Marie-Emilie Dourthe, Florian Chevillon, Karima Yakouben, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Rathana Kim, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, André Baruchel, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1433.
https://doi.org/10.1182/blood-2024-209895
Published: 2024
Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Uncovering new layers of Ph + ALL biology

Rathana Kim, Emmanuelle Clappier
Journal: Blood
Blood (2024) 143 (14): 1322–1323.
https://doi.org/10.1182/blood.2023023583
Published: 2024
Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

The Splicing-Associated Network PAK1-Clk-SRRM1 Is a Critical Vulnerability to Overcome Chemoresistance in Acute Myeloid Leukemia

Camille Vaganay, Frank Ling, Lois M. Kelly, Duong Ho Nhat, Antoine Forget, Paul-Arthur Meslin, Hélène Pasquer, Rathana Kim, Marie Passet, Sofiane Fodil, Tony Huynh, Angela H Su, Christopher F Bassil, Matthieu Duchmann, Gabriela Alexe, Gael Fortin, Carine Legrand, Khansa Saadallah, Christopher Delaney, Kim Pacchiardi, Anja Kocijancic, Lisa Aziez, Nina Fenouille, Marie Sebert, Lionel Ades, Emmanuel Raffoux, Emmanuelle Clappier, Lina Benajiba, Kimberly Stegmaier, Kris C. Wood, Raphael Itzykson, Camille Lobry, Alexandre Puissant
Journal: Blood
Blood (2023) 142 (Supplement 1): 409.
https://doi.org/10.1182/blood-2023-186264
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition

Lucien Courtois, Aurélie Cabannes-Hamy, Rathana Kim, Marine Delecourt, Antoine Pinton, Guillaume Charbonnier, Mélanie Feroul, Charlotte Smith, Giulia Tueur, Cécile Pivert, Estelle Balducci, Mathieu Simonin, Laure Hélène Angel, Salvatore Spicuglia, Nicolas Boissel, Guillaume P. Andrieu, Vahid Asnafi, Philippe Rousselot, Ludovic Lhermitte
Journal: Blood
Blood (2023) 142 (2): 158–171.
https://doi.org/10.1182/blood.2022017948
Published: 2023
Includes: Supplemental data
Journal Articles

Fractionated Inotuzumab Ozogamicin Combined with Low-Intensity Chemotherapy in Older Patients with Newly Diagnosed CD22+ Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL): Results of the EWALL-INO Study

Patrice Chevallier, Thibault Leguay, Rathana KIM, Marc Delord, Michael Doubek, Francoise Huguet, Aurelie Cabannes-Hamy, Ulla Wartiovaara-Kautto, Colombe Saillard, Emmanuel Raffoux, Thomas Cluzeau, Stephane Lepretre, Marie Balsat, Anna Berceanu, Nicolas Boissel, Claude Gardin, Emmanuelle Clappier, Herve Dombret, Philippe Rousselot
Journal: Blood
Blood (2022) 140 (Supplement 1): 6114–6116.
https://doi.org/10.1182/blood-2022-166035
Published: 2022
Journal Articles

Blinatumomab during Consolidation in High-Risk Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL) Adult Patients: A Two-Cohort Comparison within the Graall-2014/B Study

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Sébastien Maury, Anne Thiebaut-Bertrand, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre-Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Ioana Vaida, Laurence Sanhes, Magda Alexis, Cedric Pastoret, Mathlide Lamarque, Laure Farnault, Nathalie Grardel, Celine Berthon, Eric Delabesse, Veronique Lheritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 507–509.
https://doi.org/10.1182/blood-2022-159397
Published: 2022
Journal Articles

Prognostic impact of DDX41 germline mutations in intensively treated acute myeloid leukemia patients: an ALFA-FILO study

Clinical Trials & Observations
Nicolas Duployez, Laëtitia Largeaud, Matthieu Duchmann, Rathana Kim, Julie Rieunier, Juliette Lambert, Audrey Bidet, Lise Larcher, Jean Lemoine, François Delhommeau, Pierre Hirsch, Laurène Fenwarth, Olivier Kosmider, Justine Decroocq, Anne Bouvier, Yannick Le Bris, Marlène Ochmann, Alberto Santagostino, Lionel Adès, Pierre Fenaux, Xavier Thomas, Jean-Baptiste Micol, Claude Gardin, Raphael Itzykson, Jean Soulier, Emmanuelle Clappier, Christian Recher, Claude Preudhomme, Arnaud Pigneux, Hervé Dombret, Eric Delabesse, Marie Sébert
Journal: Blood
Blood (2022) 140 (7): 756–768.
https://doi.org/10.1182/blood.2021015328
Published: 2022
Includes: Supplemental data
Journal Articles

Concurrent CDX2 cis -deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL

Marie Passet, Rathana Kim, Stéphanie Gachet, François Sigaux, Julie Chaumeil, Ava Galland, Thomas Sexton, Samuel Quentin, Lucie Hernandez, Lise Larcher, Hugo Bergugnat, Tao Ye, Nezih Karasu, Aurélie Caye, Beate Heizmann, Isabelle Duluc, Patrice Chevallier, Philippe Rousselot, Françoise Huguet, Thibaut Leguay, Mathilde Hunault, Françoise Pflumio, Jean-Noël Freund, Camille Lobry, Véronique Lhéritier, Hervé Dombret, Claire Domon-Dell, Jean Soulier, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2022) 139 (24): 3505–3518.
https://doi.org/10.1182/blood.2021014723
Published: 2022
Includes: Supplemental data
Journal Articles

Clinical, pathological, and molecular features of myelodysplasia cutis

Clinical Trials & Observations
Jérémie Delaleu, Rathana Kim, Lin-Pierre Zhao, Adèle de Masson, Marie-Dominique Vignon-Pennamen, Charles Cassius, Caroline Ram-Wolff, Martine Bagot, Emmanuelle Clappier, Lionel Adès, Marie Sebert, Jean-David Bouaziz, Pierre Fenaux, Maxime Battistella
Journal: Blood
Blood (2022) 139 (8): 1251–1253.
https://doi.org/10.1182/blood.2021013967
Published: 2022
Includes: Supplemental data
Journal Articles

Frequency and Outcome of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with BCR-ABL1 Clonal Hematopoiesis after Blast Clearance: Results from the Graaph-2014 Trial

Rathana KIM, Philippe Rousselot, Jean-Michel Cayuela, Yves Chalandon, Marie Passet, Xavier Thomas, Nicole Straetmans, Patrice Chevallier, Francoise Huguet, Celine Berthon, Georg Stüssi, Sébastien Maury, Sylvain Chantepie, Jean-Baptiste Micol, Isabelle Plantier, Sylvie Chevret, Jean Soulier, Norbert Ifrah, Veronique Lheritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2021) 138 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2021-150126
Published: 2021
Journal Articles

Frontline Consolidation with Blinatumomab for High-Risk Philadelphia-Negative Acute Lymphoblastic Adult Patients. Early Results from the Graall-2014-QUEST Phase 2

Nicolas Boissel, Francoise Huguet, Carlos Graux, Yosr Hicheri, Patrice Chevallier, Rathana KIM, Marie Balsat, Thibaut Leguay, Mathilde Hunault, Sébastien Maury, Anne Thiebaut-Bertrand, Martine Escoffre-Barbe, Thomas Cluzeau, Alban Villate, Florence Pasquier, Laure Farnault, Florence Van Obbergh, Philippe Rousselot, Yves Chalandon, Eric Delabesse, Cedric Pastoret, Emmanuelle Clappier, Veronique Lheritier, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 1232.
https://doi.org/10.1182/blood-2021-146163
Published: 2021
Journal Articles

Clonal Hematopoiesis Driven By MDM4 Amplification Defines a Canonical Route Towards Secondary MDS/AML in Fanconi Anemia Patients

Marie Sebert, Stéphanie Gachet, Thierry Leblanc, Alix Rousseau, Olivier Bluteau, Rathana KIM, Raouf Benabelali, Flore Sicre de Fontbrune, Loïc Maillard, Carèle Fedronie, Nadia Vasquez, Yves Bertrand, Jean-Hugues Dalle, Francois Sigaux, Sylvie Chevret, Gerard Socie, Hugues de Thé, Christophe Antoniewski, Dominique Bluteau, Regis Peffault De Latour, Jean Soulier
Journal: Blood
Blood (2021) 138 (Supplement 1): 860.
https://doi.org/10.1182/blood-2021-147811
Published: 2021
Journal Articles

Minimal residual disease quantification in ovarian tissue collected from patients in complete remission of acute leukemia

Clinical Trials & Observations
Florian Chevillon, Emmanuelle Clappier, Chloé Arfeuille, Jean-Michel Cayuela, Jean Hugues Dalle, Rathana Kim, Aurélie Caye-Eude, Céline Chalas, Chrystelle Abdo, Véronique Drouineaud, Régis Peffault de Latour, Marion Alcantara, Madalina Uzunov, Michael Degaud, Véronique Meignin, Hervé Dombret, Nicolas Boissel, Catherine Poirot, Nathalie Dhédin
Journal: Blood
Blood (2021) 137 (12): 1697–1701.
https://doi.org/10.1182/blood.2020007782
Published: 2021
Includes: Supplemental data
Journal Articles

Myeloid Blast Crisis of Philadelphia Positive Chronic Myeloid Leukemia and Philadelphia Positive Acute Myeloid Leukemia Treated at the AP-HP in Paris: A Retrospective Analysis

Matteo Dragani, MD, Rathana Kim, PharmD, Clémence Loiseau, MD, Madalina Uzunov, MD, Felipe Suarez, MDPhD, Didier Bouscary, MDPhD, Philippe Rousselot, MDPhD, Etienne Lengline, MD, Raphael Itzykson, MD PhD, Jean Michel Cayuela, PhD, Nicolas Boissel, MD PhD, Herve Dombret, MD PhD, Delphine Rea, MDPhD, Emmanuel Raffoux, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-140998
Published: 2020
Journal Articles

A “foamy” mastocytosis case

Rathana Kim, Ludovic Lhermitte
Journal: Blood
Blood (2018) 131 (5): 586.
https://doi.org/10.1182/blood-2017-08-803726
Published: 2018
Journal Articles

To Dose or Not to Dose: Are IL-10 and IL-6 Accurate Biomarkers to Detect Leptomeningeal Involvement in Small B-Cell Lymphoproliferation?

Rathana Kim, Myrto Costopoulos, PharmD, Sylvain Choquet, MD, Karim Maloum, MD PhD, Caroline Algrin, MD, Khe Hoang-Xuan, MD PhD, Catherine Settegrana, PharmD, Juliette Villemonteix, Martine Brissard, Frederic Davi, MD PhD, Veronique Leblond, MD PhD, Helene Merle-Beral, MD PhD, Magali Le Garff-Tavernier, PharmD, PhD
Journal: Blood
Blood (2015) 126 (23): 3878.
https://doi.org/10.1182/blood.V126.23.3878.3878
Published: 2015