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Jean Claude Chomel
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Journal Articles

Thrombosis with Non-Proliferative Complete Blood Count Indicative of Underlying Myeloproliferative Neoplasm, Sythrom, a Study on Behalf of the FIM Group

Yannick LE Bris, Jean Galtier, Dina Naguib, Mathieu Wemeau, Jean Claude Chomel, Laurence Legros, Yan Beauverd, Lise Willems, Guillaume Denis, Françoise Boyer perrard, Damien Luque-Paz, Kamel Laribi, Mélanie Mercier, Pascale Cony-Makhoul, Olivier Herault, Lydia Roy, Pierre Sujobert, Lenaig Le Clech, Sylvie Tondeur, Gaelle Laboure, Jerome Rey, Guillou Sophie, Cedric Pastoret, Pascaline Etancelin, Suzanne Tavitian, Charles Bescond, Francois Girodon, Shanti Amé, Viviane Dubruille, Eric Lippert, Chloe James, Barbara Burroni, Marc Fouassier, Marie C Béné, Jean Christophe Ianotto
Journal: Blood
Blood (2022) 140 (Supplement 1): 9668–9669.
https://doi.org/10.1182/blood-2022-159928
Published: 2022
Journal Articles

Modeling Progression of CML Using Mutagenized Patient-Derived Induced Pluripotent Stem Cells (iPSCs): Potential Tool for Discovering Novel Therapeutic Targets

Jusuf Imeri, Christophe Desterke, Gladys Telliam, Paul Marcoux, Nathalie Sorel, Safa Sanekli, Sylvain Barreau, Yücel Erbilgin, Theodoros Latsis, Patricia Hugues, Emilie Cayssials, Jean Claude Chomel, Annelise Bennaceur Griscelli, Ali G Turhan
Journal: Blood
Blood (2022) 140 (Supplement 1): 12173–12174.
https://doi.org/10.1182/blood-2022-156075
Published: 2022
Journal Articles

Revisiting Early Stages of Chronic Myeloid Leukemia (CML): Evidence That Leukemic Progenitors Appear First in Peripheral Blood during Molecular Recurrence

Ali G Turhan, MD PhD, Patricia Hugues, Nathalie Sorel, Christophe Desterke, Annelise Bennaceur-Griscelli, MD PhD, Jean-Claude Chomel, PharmD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5425.
https://doi.org/10.1182/blood-2018-99-110676
Published: 2018
Journal Articles

Micro-RNA Profiling Reveals the Key Role of miR-206 in the Hematopoietic Potential of Human Embryonic and Induced Pluripotent Stem Cells

Stephane Flamant, Jean-Claude Chomel, PharmD PhD, Christophe Desterke, Olivier Feraud, Emilie Gobbo, Maria Teresa Mitjavila-Garcia, Adlen Foudi, Frank Griscelli, Ali G Turhan, MD PhD, Annelise Bennaceur-Griscelli, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1275.
https://doi.org/10.1182/blood-2018-99-110729
Published: 2018
Journal Articles

Prediction of One-Year Molecular Response to Imatinib at Diagnosis of Chronic Myeloid Leukemia By Scoring Gene Expression Levels of Antioxidant Enzymes

Frederic Picou, PhD, Jean-Claude Chomel, PharmD PhD, Marie Christine Bene, PharmD, Marc G. Berger, MD PhD, Thierry Fest, Valerie Ugo, MD PhD, Eric Lippert, MD PhD, Marion Socco-Luca, Martine Delain, MD, Marie-Helene Estienne, PharmD, Olivier Herault, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3024.
https://doi.org/10.1182/blood-2018-99-118297
Published: 2018
Journal Articles

ETS1 Expression Is Upregulated in Chronic Myeloid Leukemia (CML) and the ETS1 Transcriptional Program Correlates with Disease Progression Towards Blast Crisis

Christophe Desterke, PhD, Maud Voldoire, MD, Nathalie Sorel, Marie Laure Bonnet, Sarah Pagliaro, PharmD, Annelise Bennaceur-Griscelli, MD PhD, Emilie Cayssials, MD, Jean-Claude Chomel, PharmD PhD, Ali G Turhan, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 442.
https://doi.org/10.1182/blood.V128.22.442.442
Published: 2016
Journal Articles

The Cell Surface NADH Oxidase ENOX2 Is Highly Expressed in Chronic Myeloid Leukemia (CML): a Redox Protein As a Secreted Surrogate Biomarker and Druggable Target

Seda Baykal, Maud Voldoire, MD, Christophe Desterke, Nathalie Sorel, Hyacinthe Atchroue Johnson Ansah, Agnes Guerci-Bresler, MD, Jean-Claude Chomel, PharmD PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 3059.
https://doi.org/10.1182/blood.V128.22.3059.3059
Published: 2016
Journal Articles

Combination of Dasatinib and Peg-Interferon Alpha 2b in Chronic Phase Chronic Myeloid Leukemia (CP-CML) First Line: Preliminary Results of a Phase II Trial, from the French Intergroup of CML (Fi-LMC)

Lydia ROY, MD, Jean-Claude Chomel, PharmD PhD, Joelle Guilhot, PhD, Agnes Guerci-Bresler, MD, Martine Escoffre-Barbe, Stéphane Giraudier, MD PhD, Aude Charbonnier, Viviane Dubruille, MD, Françoise Huguet, Hyacinthe Johnson-Ansah, MD, Pascal Lenain, MD, Shanti Amé, MD, Gabriel Etienne, MD PhD, Franck E. Nicolini, Delphine Rea, MD PhD, Pascale Cony-Makhoul, MD, Stephane Courby, MD, Jean-Christophe Ianotto, MD, Laurence Legros, MD, Martine Delain, MD, Valérie Coiteux, MD, Eric Hermet, MD, Martine Gardembas, MD, Mathieu Molimard, MD PhD, Jean-Michel Cayuela, Marie Thibaud, CRA, Sophie Duranton, PharmD, Francois-Xavier Mahon, MD PhD, Philippe Rousselot, MD PhD Professor, Francois Guilhot, MD
Journal: Blood
Blood (2015) 126 (23): 134.
https://doi.org/10.1182/blood.V126.23.134.134
Published: 2015
Journal Articles

A Novel DNA Repair Chip Assay Allows Rapid Identification of DNA Repair Abnormalities Induced By BCR-ABL

Ali G Turhan, MD PhD, Fanny Sarrazy, Marie Laure Bonnet, Angelina Bertrand, Marie Claude Meunier, Djamel Aggoune, Jean-Claude Chomel, PharmD, PhD, Olivier Feraud, Sylvain Caillat, Annelise Bennaceur-Griscelli, MD PhD, Sylvie Sauvaigo, PhD
Journal: Blood
Blood (2014) 124 (21): 4536.
https://doi.org/10.1182/blood.V124.21.4536.4536
Published: 2014
Journal Articles

Superoxide Dismutase 2 (Sod2) Expression Is Highly Decreased In Chronic Myeloid Leukemia (CML): Contribution To Genetic Instability In Bcr-Abl-Expressing Leukemic Cells

Sandrine Girerd, Lucie Tosca, PharmD, PhD, Olivier Herault, MD, PhD, Christine Vignon, PhD, Denis Biard, PhD, Fatima Dkhissi, PhD, Clémentine Bouneau, Djamel Aggoune, Angelina Bertrand, Marie Laure Bonnet, Nathalie Sorel, PhD, Gerard Tachdjian, MD, PhD, François Guilhot, MD, Joelle Guilhot, PhD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3980.
https://doi.org/10.1182/blood.V122.21.3980.3980
Published: 2013
Journal Articles

Interferon-Inducible Protein 16 (IFI-16) Is Upregulated In Chronic Myeloid Leukemia (CML) and Is Involved In Oncogene-Induced Senescence

Clémentine Bouneau, Marie Laure Bonnet, Marie Claude Meunier, Djamel Aggoune, Fatima Dkhissi, PhD, François Guilhot, MD, Annelise Bennaceur-Griscelli, MD, PhD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2708.
https://doi.org/10.1182/blood.V122.21.2708.2708
Published: 2013
Journal Articles

BRCA1-Down-Regulation In Chronic Myeloid Leukemia (CML) Occurs Via The Deubiquitinase / Tumor Suppressor BRCA1-Associated Protein 1 (BAP1)

Fatima Dkhissi, PhD, Djamel Aggoune, Julien Pontis, Marie Laure Bonnet, Marie Claude Meunier, Nathalie Sorel, PhD, Clémentine Bouneau, Annelise Bennaceur-Griscelli, MD, PhD, François Guilhot, MD, Jean-Claude Chomel, PharmD, PhD, Slimane Ait-Si-Ali, PhD, Ali G Turhan, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3813.
https://doi.org/10.1182/blood.V122.21.3813.3813
Published: 2013
Journal Articles

T315I-Mutated BCR-ABL Induces a Distinct and Specific Molecular Signature With High Expression Of Zinc Finger (ZNF) Transcription Factors

Christophe Desterke, PhD, Djamel Aggoune, Marie Laure Bonnet, Nais Prade, Jean-Claude Chomel, PharmD, PhD, Eric Delabesse, MD, PhD, Ali G Turhan, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4899.
https://doi.org/10.1182/blood.V122.21.4899.4899
Published: 2013
Journal Articles

Sequential Measurement Of JAK2 V617F Allele Burden In Polycythemia Vera and Essential Thrombocythemia Reveals Different Evolution Profiles: First Results Of Jaksuivi, a Multicentre Study By The French Intergroup Of Myeloproliferative Neoplasms (FIM)

Caroline Buors, Françoise Boyer, Aline Tanguy-Schmidt, Aurélie Chauveau, Lydia Roy, MD, Jean-Claude Chomel, PharmD, PhD, Thierry Lamy, MD, PhD, Olivier Fardel, Olivier Herault, MD, PhD, Laura Samaison, Valérie Ugo, MD, PhD, Jean-Christophe Ianotto, MD
Journal: Blood
Blood (2013) 122 (21): 1593.
https://doi.org/10.1182/blood.V122.21.1593.1593
Published: 2013
Journal Articles

Loss Of Major Molecular Response As a Trigger For Restarting Tyrosine Kinase Inhibitor Therapy In CP-CML Patients Who Have Stopped Imatinib After Durable Undetectable Minimal Residual Disease

Philippe Rousselot, Aude Charbonnier, Pascale Cony-Makhoul, Philippe Agape, Franck E Nicolini, MD, PhD, Bruno R. Varet, MD, Martine Gardembas, Gabriel Etienne, Delphine Rea, Lydia Roy, Martine Escoffre-Barbe, Agnès Guerci-Bresler, Michel Tulliez, Stephane Prost, Marc Spentchian, Jean-Michel Cayuela, Josy Reiffers, MD, Jean Claude Chomel, Ali G Turhan, M.D., PhD, Joelle Guilhot, PhD, Francois Guilhot, MD, Francois-Xavier Mahon, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 381.
https://doi.org/10.1182/blood.V122.21.381.381
Published: 2013
Journal Articles

Evaluation of Leukemic Stem Cell Persistence in Chronic Myeloid Leukemia (CML) Patients in Complete Molecular Remission Induced by First Line TKI Therapies

Jean-Claude Chomel, PharmD, PhD, Marie Laure Bonnet, Nathalie Sorel, PhD, Ivan Sloma, PharmD, PhD, Alexis Proust, Annelise Bennaceur-Griscelli, MD, PhD, Delphine Rea, MD, PhD, Madalina Uzunov, M.D., Laurence Legros, MD, PhD, Shanti Ame, MD, Anne Marfaing-Koka, Agnès Guerci, MD, Philippe Rousselot, MD, PhD, Ali G Turhan, M.D., PhD
Journal: Blood
Blood (2012) 120 (21): 3726.
https://doi.org/10.1182/blood.V120.21.3726.3726
Published: 2012
Journal Articles

A Niche-Based Cell Mutagenesis Assay Identifies ABL-Kinase Mutations Appearing in BCR-ABL T315I-Mutated Leukemic Cells Treated with Ponatinib.

Djamel Aggoune, Nathalie Sorel, PhD, Marie Laure Bonnet, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, M.D., PhD
Journal: Blood
Blood (2012) 120 (21): 2436.
https://doi.org/10.1182/blood.V120.21.2436.2436
Published: 2012
Journal Articles

Molecular Characterization of the Leukemic Niche in Chronic Myeloid Leukemia (CML) and Evaluation of a Leukemia / Niche Cross-Talk

Djamel Aggoune, Nathalie Sorel, PhD, Sanaa El Marsafy, MD, PhD, Marie Laure Bonnet, Denis Clay, Marie Claude Meunier, Karin Tarte, Olivier Herault, MD, PhD, Jorge Domenech, MD, PhD, Agnès Guerci, MD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, M.D., PhD
Journal: Blood
Blood (2012) 120 (21): 908.
https://doi.org/10.1182/blood.V120.21.908.908
Published: 2012
Journal Articles

BCR-ABL expression in leukemic progenitors and primitive stem cells of patients with chronic myeloid leukemia

Jean-Claude Chomel, Nathalie Sorel, Joëlle Guilhot, François Guilhot, Ali G. Turhan
Journal: Blood
Blood (2012) 119 (12): 2964–2965.
https://doi.org/10.1182/blood-2011-12-396226
Published: 2012
Journal Articles

Leukemic stem cell persistence in chronic myeloid leukemia patients with sustained undetectable molecular residual disease

Brief Report
Jean-Claude Chomel, Marie-Laure Bonnet, Nathalie Sorel, Angelina Bertrand, Marie-Claude Meunier, Serge Fichelson, Michael Melkus, Annelise Bennaceur-Griscelli, François Guilhot, Ali G. Turhan
Journal: Blood
Blood (2011) 118 (13): 3657–3660.
https://doi.org/10.1182/blood-2011-02-335497
Published: 2011
Includes: Supplemental data