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Journal Articles

Spatial Transcriptomic Profiling of Bone Marrow Vascular Niches Unveils an Endothelial Stress Signature in Myeloproliferative Neoplasms

Jimena Castorena, Christophe Desterke, Barbara Burroni, Lise Willems, Marie-Caroline Le Bousse-Kerdilès, Laurence Legros, Laura Velazquez

Blood (2024) 144 (Supplement 1): 4516.

https://doi.org/10.1182/blood-2024-210924

Published: 2024

Journal Articles

Single Cell Analysis of Genes Involved in Asymmetric Hematopoietic Stem Cell (HSC) Division in Chronic Myeloid Leukemia (CML) : Evidence of the Regulation of Tetraspanin CD63 during Leukemia Progression

Christophe Desterke, Annelise Bennaceur Griscelli, Ali Turhan

Blood (2023) 142 (Supplement 1): 3159.

https://doi.org/10.1182/blood-2023-174622

Published: 2023

Journal Articles

Chimeric Antigen-Receptor (CAR)-Engineered Natural Killer (NK) Cells Targeting Chronic Myeloid Leukemia (CML) Blast Crisis

Jusuf Imeri, Paul Marcoux, Matthias Huyghe, Christophe Desterke, Daianne Fantacini, Frank Griscelli, Dimas T. Covas, Lucas Edouardo Botelho de Souza, Annelise Bennaceur Griscelli, Ali Turhan

Blood (2023) 142 (Supplement 1): 4514.

https://doi.org/10.1182/blood-2023-174620

Published: 2023

Journal Articles

Comparative Transcriptome Analyses in Mantle Cell Lymphoma (MCL): Evidence of E2F1 As a Major Target in Aggressive Blastoid MCL Model

Jusuf Imeri, Paul Marcoux, Christophe Desterke, Amen Allah Nasr, Radhia M'kacher, Annelise Bennaceur Griscelli, Ali Turhan

Blood (2023) 142 (Supplement 1): 5731.

https://doi.org/10.1182/blood-2023-174618

Published: 2023

Journal Articles

Modeling Progression of CML Using Mutagenized Patient-Derived Induced Pluripotent Stem Cells (iPSCs): Potential Tool for Discovering Novel Therapeutic Targets

Jusuf Imeri, Christophe Desterke, Gladys Telliam, Paul Marcoux, Nathalie Sorel, Safa Sanekli, Sylvain Barreau, Yücel Erbilgin, Theodoros Latsis, Patricia Hugues, Emilie Cayssials, Jean Claude Chomel, Annelise Bennaceur Griscelli, Ali G Turhan

Blood (2022) 140 (Supplement 1): 12173–12174.

https://doi.org/10.1182/blood-2022-156075

Published: 2022

Journal Articles

BCR::ABL1 -Dependent Promotion of Hematopoietic Stem Cells (HSC) and Progenitors in an Inducible Embryonic Stem Cell (ESC) Model

Jerome Artus, Alina Zench, Isidora Simanic, Christophe Desterke, Denis Clay, Lucas de Souza, Sabrina Coignard, Annelise Bennaceur Griscelli, Ali G Turhan, Adlen Foudi

Blood (2022) 140 (Supplement 1): 12150–12152.

https://doi.org/10.1182/blood-2022-156353

Published: 2022

Journal Articles

The Anti-HIV Drug Nelfinavir Exhibits Synergistic Activity with Tyrosine Kinase Inhibitors and Circumvents TKI-Resistance Conferred By T315I-Mutated BCR-ABL

Yücel Erbilgin, Christophe Desterke, Annelise Bennaceur Griscelli, Ali G Turhan

Blood (2022) 140 (Supplement 1): 3871–3872.

https://doi.org/10.1182/blood-2022-156350

Published: 2022

Journal Articles

The Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding and Represents a Druggable Target

Christophe Desterke, PhD, Sarah Pagliaro, Pharm D, Patricia Hugues, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2019) 134 (Supplement_1): 1632.

https://doi.org/10.1182/blood-2019-124796

Published: 2019

Journal Articles

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

Ivan Sloma, PharmD, PhD, Philip Beer, PhD FRCPath, MRCP, Christophe Desterke, PhD, Elizabeth Bulaeva, Misha Bilenky, Michelle Moksa, Kamini Raghuram, Cedric Brimacombe, Karen Lambie, Ali G Turhan, MD PhD, Orianne Wagner-Ballon, MD PhD, Philippe Gaulard, MD PhD, R. Keith Humphries, MD PhD, Martin Hirst, PhD BS, Connie J. Eaves, PhD

Blood (2019) 134 (Supplement_1): 4139.

https://doi.org/10.1182/blood-2019-127839

Published: 2019

Journal Articles

DIS3 Mutation in RUNX1-Mutated AML1 Confers a Highly Dismal Prognosis in AML By Repressing Sister Chromatid Cohesion

Christophe Desterke, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2019) 134 (Supplement_1): 1454.

https://doi.org/10.1182/blood-2019-123352

Published: 2019

Journal Articles

Revisiting Early Stages of Chronic Myeloid Leukemia (CML): Evidence That Leukemic Progenitors Appear First in Peripheral Blood during Molecular Recurrence

Ali G Turhan, MD PhD, Patricia Hugues, Nathalie Sorel, Christophe Desterke, Annelise Bennaceur-Griscelli, MD PhD, Jean-Claude Chomel, PharmD PhD

Blood (2018) 132 (Supplement 1): 5425.

https://doi.org/10.1182/blood-2018-99-110676

Published: 2018

Journal Articles

Micro-RNA Profiling Reveals the Key Role of miR-206 in the Hematopoietic Potential of Human Embryonic and Induced Pluripotent Stem Cells

Stephane Flamant, Jean-Claude Chomel, PharmD PhD, Christophe Desterke, Olivier Feraud, Emilie Gobbo, Maria Teresa Mitjavila-Garcia, Adlen Foudi, Frank Griscelli, Ali G Turhan, MD PhD, Annelise Bennaceur-Griscelli, MD PhD

Blood (2018) 132 (Supplement 1): 1275.

https://doi.org/10.1182/blood-2018-99-110729

Published: 2018

Journal Articles

A Novel Metabolic Transcriptome Identified in Myelodysplastic Syndromes (MDS) Correlates with OMS Classification and Poor Prognosis

Christophe Desterke, Estelle Balducci, Xavier Fund, Claire Borie, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2018) 132 (Supplement 1): 5495.

https://doi.org/10.1182/blood-2018-99-110678

Published: 2018

Journal Articles

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

Sarah Pagliaro, Pharm D, Christophe Desterke, Herve Acloque, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD

Blood (2018) 132 (Supplement 1): 934.

https://doi.org/10.1182/blood-2018-99-110679

Published: 2018

Journal Articles

ETS1 Expression Is Upregulated in Chronic Myeloid Leukemia (CML) and the ETS1 Transcriptional Program Correlates with Disease Progression Towards Blast Crisis

Christophe Desterke, PhD, Maud Voldoire, MD, Nathalie Sorel, Marie Laure Bonnet, Sarah Pagliaro, PharmD, Annelise Bennaceur-Griscelli, MD PhD, Emilie Cayssials, MD, Jean-Claude Chomel, PharmD PhD, Ali G Turhan, MD, PhD

Blood (2016) 128 (22): 442.

https://doi.org/10.1182/blood.V128.22.442.442

Published: 2016

Journal Articles

The Cell Surface NADH Oxidase ENOX2 Is Highly Expressed in Chronic Myeloid Leukemia (CML): a Redox Protein As a Secreted Surrogate Biomarker and Druggable Target

Seda Baykal, Maud Voldoire, MD, Christophe Desterke, Nathalie Sorel, Hyacinthe Atchroue Johnson Ansah, Agnes Guerci-Bresler, MD, Jean-Claude Chomel, PharmD PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD, PhD

Blood (2016) 128 (22): 3059.

https://doi.org/10.1182/blood.V128.22.3059.3059

Published: 2016

Journal Articles

Pathological Heterotopic Ossifications in Brain or Spinal Cord Injured Patients: From Ectopic Bone to Hematopoietic Stem Cell Niche Development

Frédéric Torossian, PhD, Bernadette Guerton, Adrienne Anginot, PhD, Nassim Arouche, Laetitia Boutin, Denis Clay, Nathalie Rochet, PhD MD, Christophe Desterke, PhD, Erica Vlachos, Guillaume Genet, Philippe Denormandie, PhD MD, François Genet, PhD MD, Jean-Pierre Levesque, PhD, Jean-Jacques Lataillade, PhD MD, Marie-Caroline Le Bousse-Kerdiles, PhD

Blood (2016) 128 (22): 3889.

https://doi.org/10.1182/blood.V128.22.3889.3889

Published: 2016

Journal Articles

Blast Crisis in a Dish: Generation of a Blast Crisis Model in Chronic Myeloid Leukemia (CML) Using Patient-Specific Induced Pluripotent Stem Cells ( iPSC)

Gladys Telliam, Christophe Desterke, PhD, Olivier Féraud, PhD, Frank Griscelli, PharmD, PhD, Noufissa Oudrhiri, Micheline Fontaine Arnoux, Radhia Najar, PhD, Herve Acloque, PhD, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD, PhD

Blood (2016) 128 (22): 933.

https://doi.org/10.1182/blood.V128.22.933.933

Published: 2016

Journal Articles

Accessible Chromatin Landscape Reveals a Proliferative Osteoprogenitor Transcriptional Program in Bone Marrow Mesenchymal Stromal Cells from Patients with Primary Myelofibrosis

Christophe Desterke, PhD, Nadira Ruzehaji, PhD, Bernadette Guerton, Johanna Konopacki, MD, Solene-Florence Kammerer-Jacquet, MD, Alessandro M. Vannucchi, MD PhD, Lisa Pieri, MD PhD, Christophe Martinaud, MD PhD, Marie-Caroline Le Bousse-Kerdiles, PhD

Blood (2016) 128 (22): 3135.

https://doi.org/10.1182/blood.V128.22.3135.3135

Published: 2016

Journal Articles

A Bio-Integrative Approach Identifies an Inflammatory Signature in Chronic Myeloid Leukemia (CML) Stem Cells That Is Highly Perturbed in CML Blast Crisis and Involves REL transcription Factor

Christophe Desterke, PhD, Ludovic Marie-Sainte, Amine Sbitti, PhD, Ali Naama, Annelise Bennaceur-Griscelli, MD PhD, Ali G Turhan, MD PhD, Ivan Sloma, PharmD,PhD

Blood (2015) 126 (23): 4017.

https://doi.org/10.1182/blood.V126.23.4017.4017

Published: 2015

NARROW

Spatial Transcriptomic Profiling of Bone Marrow Vascular Niches Unveils an Endothelial Stress Signature in Myeloproliferative Neoplasms

Single Cell Analysis of Genes Involved in Asymmetric Hematopoietic Stem Cell (HSC) Division in Chronic Myeloid Leukemia (CML) : Evidence of the Regulation of Tetraspanin CD63 during Leukemia Progression

Chimeric Antigen-Receptor (CAR)-Engineered Natural Killer (NK) Cells Targeting Chronic Myeloid Leukemia (CML) Blast Crisis

Comparative Transcriptome Analyses in Mantle Cell Lymphoma (MCL): Evidence of E2F1 As a Major Target in Aggressive Blastoid MCL Model

Modeling Progression of CML Using Mutagenized Patient-Derived Induced Pluripotent Stem Cells (iPSCs): Potential Tool for Discovering Novel Therapeutic Targets

BCR::ABL1 -Dependent Promotion of Hematopoietic Stem Cells (HSC) and Progenitors in an Inducible Embryonic Stem Cell (ESC) Model

The Anti-HIV Drug Nelfinavir Exhibits Synergistic Activity with Tyrosine Kinase Inhibitors and Circumvents TKI-Resistance Conferred By T315I-Mutated BCR-ABL

The Embryonic Program Activated during Blast Crisis of Chronic Myelogenous Leukemia (CML) Implicates a TCF7L2 and MYC Cooperative Chromatin Binding and Represents a Druggable Target

NUP98-HOXA9 -Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML

DIS3 Mutation in RUNX1-Mutated AML1 Confers a Highly Dismal Prognosis in AML By Repressing Sister Chromatid Cohesion

Revisiting Early Stages of Chronic Myeloid Leukemia (CML): Evidence That Leukemic Progenitors Appear First in Peripheral Blood during Molecular Recurrence

Micro-RNA Profiling Reveals the Key Role of miR-206 in the Hematopoietic Potential of Human Embryonic and Induced Pluripotent Stem Cells

A Novel Metabolic Transcriptome Identified in Myelodysplastic Syndromes (MDS) Correlates with OMS Classification and Poor Prognosis

Single Cell Transcriptome in Chronic Myeloid Leukemia (CML): Pseudotime Analysis Reveals a Rare Population with Embryonic Stem Cell Features and Druggable Intricated Transitional Stem Cell States

ETS1 Expression Is Upregulated in Chronic Myeloid Leukemia (CML) and the ETS1 Transcriptional Program Correlates with Disease Progression Towards Blast Crisis

The Cell Surface NADH Oxidase ENOX2 Is Highly Expressed in Chronic Myeloid Leukemia (CML): a Redox Protein As a Secreted Surrogate Biomarker and Druggable Target

Pathological Heterotopic Ossifications in Brain or Spinal Cord Injured Patients: From Ectopic Bone to Hematopoietic Stem Cell Niche Development

Blast Crisis in a Dish: Generation of a Blast Crisis Model in Chronic Myeloid Leukemia (CML) Using Patient-Specific Induced Pluripotent Stem Cells ( iPSC)

Accessible Chromatin Landscape Reveals a Proliferative Osteoprogenitor Transcriptional Program in Bone Marrow Mesenchymal Stromal Cells from Patients with Primary Myelofibrosis

A Bio-Integrative Approach Identifies an Inflammatory Signature in Chronic Myeloid Leukemia (CML) Stem Cells That Is Highly Perturbed in CML Blast Crisis and Involves REL transcription Factor

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American Society of Hematology

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American Society of Hematology

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