1-20 of 34
Dan A. Landau
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Transcriptomic and Epigenomic Landscape of Hairy Cell Leukemia at Single-Cell Resolution

Elliot O. Eton, Saravanan Ganesan, Rebecca M. Murray, Benjamin H. Durham, Jae H. Park, Omar Abdel-Wahab, Dan A. Landau
Journal: Blood
Blood (2024) 144 (Supplement 1): 1604.
https://doi.org/10.1182/blood-2024-210195
Published: 2024
Journal Articles

Topic Modeling of Genotyping of Transcriptomes Reveals Collaboration between BTK C481S -Mutant and Wild Type Cells in Btki-Resistant Chronic Lymphocytic Leukemia

Ramon Massoni-Badosa, Joshua S. Schiffman, Barun Pradhan, Rebecca M. Murray, Andrew H. Lipsky, Debra Van Egeren, Danny Luan, Shirley Chen, Ronan Chaligne, Kai Beattie, Alyssa Indart, Nada Chraiki, Neville Dusaj, Erica B. Bhavsar, Chelston Ang, Anna S. Nam, Federico Gaiti, Paulina Chamely, Nathaniel D. Omans, Preeti Trisal, Anita K. Gandhi, Kyu-Tae Kim, Rafael Schulman, Franco Izzo, Gavriel Mullokandov, Chingiz Underbayev, Jan A. Burger, Adrian Wiestner, Elisa Ten Hacken, John N. Allan, Jennifer A. Woyach, Richard R. Furman, Dan A. Landau
Journal: Blood
Blood (2024) 144 (Supplement 1): 4610.
https://doi.org/10.1182/blood-2024-205727
Published: 2024
Journal Articles

m 6 a-Son-CCL5 Axis Controls HSC Fate and Inflammation

Hanzhi Luo, Mariela Cortés-López, Cyrus L. Tam, Michael Xiao, Isaac Wakiro, Karen L. Chu, Aspen Pierson, Mandy Chan, Kathryn Chang, Xuejing Yang, Grace Han, Erin Ahn, Quaid D. Morris, Dan A. Landau, Michael G. Kharas
Journal: Blood
Blood (2023) 142 (Supplement 1): 1297.
https://doi.org/10.1182/blood-2023-179552
Published: 2023
Journal Articles

T-Cell Signaling Mediates the Epigenetic Priming of Germinal Center B-Cell Plasticity and Stem Functionality

Laurianne Scourzic, Franco Izzo, Lucretia Cucereavii, Matthew Teater, Alexander Polyzos, Christopher Chin, Coraline Mlynarczyk, Ioanna Tsialta, Robert M Myers, Wendy Béguelin, Matthias Stadtfeld, Zhengming Chen, Dan A. Landau, Ari M Melnick, Eftychia Apostolou
Journal: Blood
Blood (2023) 142 (Supplement 1): 2767.
https://doi.org/10.1182/blood-2023-190437
Published: 2023
Journal Articles

Deconvoluting Clonal and Cellular Architecture in IDH -Mutant Acute Myeloid Leukemia

Maria Sirenko, Soobeom Lee, Zhengxi Sun, Ronan Chaligne, Georgios Asimomitis, Charlotte K Brierley, Elsa Bernard, Sheng F. Cai, Robert M Myers, Bettina Nadorp, Max F Levine, Dylan Domenico, Juan E Arango Ossa, Juan Santiago Medina Martinez, Kamal Menghrajani, Audrey Lasry, Alice Mims, Helee Desai, Andrea Laganson, Christopher Famulare, Minal Patel, Gerard Lozanski, Sanam Loghavi, Kelly L. Bolton, Aaron D. Viny, Mikhail Roshal, Ross L Levine, Eytan M. Stein, Dan A. Landau, Ann-Kathrin Eisfeld, Iannis Aifantis, Elli Papaemmanuil
Journal: Blood
Blood (2023) 142 (Supplement 1): 1591.
https://doi.org/10.1182/blood-2023-186322
Published: 2023
Journal Articles

Genotype-Phenotype Mapping Via Single-Cell Multi-Omics Identifies Therapeutic Vulnerabilities in Vexas Syndrome

Saravanan Ganesan, Rebecca Murray, Jesus Sotelo, Theo Botella, Elliot Eton, Nada Chraiki, Carolyne Croizier, Franco Izzo, Catherine Potenski, Benjamin Terrier, Mael Heiblig, Pierre Sujobert, Olivier Kosmider, David B Beck, Dan A. Landau
Journal: Blood
Blood (2023) 142 (Supplement 1): 813.
https://doi.org/10.1182/blood-2023-184313
Published: 2023
Journal Articles

Molecular Attributes of CAR T Cell Fitness in Patients with Chronic Lymphocytic Leukemia

Xiaoli Mi, Dennis Yuan, Rebecca Murray, Jani Huuhtanen, Beatrice Zhang, Jean Quentin, Olga Shestova, David L. Porter, Satu Mustjoki, Saar Gill, Dan A. Landau
Journal: Blood
Blood (2023) 142 (Supplement 1): 3452.
https://doi.org/10.1182/blood-2023-187956
Published: 2023
Journal Articles

N/KRAS -Mutant AML LSCs Originate from Committed Myelomonocytic Progenitors and Drive Clinical Resistance to Venetoclax

Junya Sango, Saul Carcamo, Nataly Cruz-Rodriguez, Maria Sirenko, Abhishek Maiti, Malgorzata Olszewska, Tiansu Wang, Gulay Bengu Ulukaya, Lewis Tomalin, Emmanuel Olivier, Manon Jaud, Ronan Chaligne, Hager Mansour, Deniz Demircioglu, Dan A. Landau, Elli Papaemmanuil, Courtney D. DiNardo, Dan Hasson, Marina Y. Konopleva, Eirini Papapetrou
Journal: Blood
Blood (2023) 142 (Supplement 1): 403.
https://doi.org/10.1182/blood-2023-187695
Published: 2023
Journal Articles

Jak2 V617F Reversible Activation Shows an Essential Requirement for Jak2 V617F in Myeloproliferative Neoplasms (MPNs)

Andrew Dunbar, Robert L. Bowman, Young Park, Franco Izzo, Robert M. Myers, Abdul Karzai, Won Jun Kim, Inés Fernández Maestre, Michael R. Waarts, Abbas Nazir, Wenbin Xiao, Max Brodsky, Mirko Farina, Louise Cai, Sheng F Cai, Benjamin Wang, Wenbin An, Julie Yang, Shoron Mowla, Shira E. Eisman, Tanmay Mishra, Remie Houston, Emily Guzzardi, Anthony R. Martinez Benitez, Aaron D Viny, Richard Koche, Dan A. Landau, Ross L. Levine
Journal: Blood
Blood (2022) 140 (Supplement 1): 803–804.
https://doi.org/10.1182/blood-2022-164827
Published: 2022
Journal Articles

A BAX door to venetoclax resistance

Franco Izzo, Dan A. Landau
Journal: Blood
Blood (2022) 139 (8): 1124–1126.
https://doi.org/10.1182/blood.2021013788
Published: 2022
Journal Articles

Single-Cell Multi-Omics Reveals That Pegylated Interferon-Alfa Treatment Differentially Redirects Mutated and Wildtype Hematopoietic Cell Differentiation Trajectories in CALR- mutated Essential Thrombocythemia (ET) Patients

Shira Rosenberg, Andrea Kubas-Meyer, Neelang Parghi, Nathaniel D. Omans, Neville Dusaj, Paulina Chamely, Eleni Mimitou, Amylou C. Dueck, Heidi E. Kosiorek, Rona Singer Weinberg, Peter Smibert, Ronan Chaligne, Dan A. Landau, Ronald Hoffman, Anna S Nam
Journal: Blood
Blood (2021) 138 (Supplement 1): 57.
https://doi.org/10.1182/blood-2021-150745
Published: 2021
Journal Articles

High Throughput Single-Cell Simultaneous Genotyping and Chromatin Accessibility Reveals Genotype to Phenotype Relationship in Human Myeloproliferation

Robert M. Myers, Franco Izzo, Tamara Prieto, Eleni Mimitou, Ramya Raviram, Ronan Chaligne, Ronald Hoffman, Maximilian Stahl, Omar Abdel-Wahab, Bridget Marcellino, Peter Smibert, Dan A. Landau
Journal: Blood
Blood (2021) 138 (Supplement 1): 678.
https://doi.org/10.1182/blood-2021-149226
Published: 2021
Journal Articles

Single-Cell Multi-Omics Defines the Cell-Type Specific Impact of SF3B1 Splicing Factor Mutations on Hematopoietic Differentiation in Human Clonal Hematopoiesis and Myelodysplastic Syndromes

Federico Gaiti, Allegra Hawkins, Paulina Chamely, Ariel Swett, Xiaoguang Dai, Lloyd Kluegel, Celine Chen, John Beaulaurier, Alex Drong, Scott Hickey, Tarek H Mouhieddine, Franco Izzo, Neville Dusaj, Ronan Chaligne, Sissel Juul, Daniel H Wiseman, Eoghan Harrington, Justin Taylor, Irene M. Ghobrial, Omar Abdel-Wahab, Dan A. Landau
Journal: Blood
Blood (2021) 138 (Supplement 1): 145.
https://doi.org/10.1182/blood-2021-147529
Published: 2021
Journal Articles

Single-Cell Multi-Omics in Human Clonal Hematopoiesis Reveals That DNMT3A R882 Mutations Perturb Early Progenitor States through Selective Hypomethylation

Anna S Nam, MD, Neville Dusaj, MS, Franco Izzo, PhD, Rekha Murali, MS, Tarek H Mouhieddine, MD, Robert M Myers, Jesus Sotelo, Salima Benbarche, PhD, Federico Gaiti, PhD, Sabrin Tahri, MD MSc, Omar Abdel-Wahab, MD, Irene M. Ghobrial, MD, Ronan Chaligne, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-142574
Published: 2020
Journal Articles

Multiplatform Profiling Characterizes Functional Networks in Genomically Stable and Instable Chronic Lymphocytic Leukemia

Johannes Bloehdorn, MD, Andrejs Braun, PhD, Billy Michael Chelliah Jebaraj, PhD, Amaro Taylor-Weiner, PhD, Sandra Robrecht, PhD, Julia Krzykalla, PhD, Karlheinz Holzmann, PhD, Harvey Johnston, PhD, Tetyana Klymenko, PhD, Barbara Eichhorst, MD, Ru-Fang Yeh, PhD, Martin Weisser, MD, Jennifer Edelmann, MDPhD, Kirsten Fischer, MD, John G. Gribben, MD DSc, FRCP, FRCPath, FMedSci, Dan A. Landau, MD PhD, Donna S. Neuberg, ScD, Mark S Cragg, PhD, Axel Benner, Michael Hallek, MD, Catherine J. Wu, MD, Hartmut Döhner, Stephan Stilgenbauer, MD, Daniel Mertens, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-141552
Published: 2020
Journal Articles

Single-Cell Multi-Omics Reveals Distinct Paths to Survival of Admixed BTK C481 Mutant Vs. Wild-Type Cells in Clinically Progressing Chronic Lymphocytic Leukemia

Andrew Lipsky, MD, Danny Luan, MPH, Shirley Chen, BSc, Ronan Chaligne, PhD, Neville Dusaj, MS, Erica B Bhavsar, BS, Chelston Ang, MS, Anna S Nam, MD, Federico Gaiti, PhD, Paulina Chamely, MSc, Nathaniel D. Omans, MS, Preeti Trisal, MS, Anita K Gandhi, PhD, Kyu-Tae Kim, PhD, Rafael Schulman, BS, Joshua S. Schiffman, PhD, Franco Izzo, PhD, Gregory Mullokandov, MD PhD, Chingiz Underbayev, MD PhD, Adrian Wiestner, MD PhD, John N. Allan, MD, Richard R. Furman, MD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–42.
https://doi.org/10.1182/blood-2020-138374
Published: 2020
Journal Articles

Robust Discovery of Candidate DNA Methylation Cancer Drivers

Heng Pan, PhD, Loïc Renaud, MD MSc, Ronan Chaligne, PhD, Johannes Bloehdorn, MD, Eugen Tausch, MD, Daniel Mertens, PhD, Anna-Maria Fink, MD, Kirsten Fischer, MD, Chao Zhang, PhD, Doron Betel, PhD, Andreas Gnirke, Marcin Imielinski, Jerome Moreaux, PhD, Michael Hallek, Alexander Meissner, PhD, Stephan Stilgenbauer, MD, Catherine J. Wu, MD, Olivier Elemento, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-136830
Published: 2020
Journal Articles

Single Cell Approaches - Drilling Down Deeper Using Technology and Integrated Data Analyses

Dan A. Landau, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-28.
https://doi.org/10.1182/blood-2019-121046
Published: 2019
Journal Articles

m 6 A Maintains Hematopoietic Stem and Progenitor Cell Identity

Yuanming Cheng, PhD, Hanzhi Luo, PhD, Franco Izzo, PhD, Brian F Pickering, PhD, Ly P Vu, PhD, Alexandra Schurer, BS, Saroj Gourkanti, BA, Samie R. Jaffrey, MD PhD, Dan A. Landau, MD PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 327.
https://doi.org/10.1182/blood-2018-99-117191
Published: 2018
Journal Articles

High Throughput Droplet Single-Cell Genotyping of Transcriptomes (GoT) Reveals the Cell Identity Dependency of the Transcriptional Output of Somatic Mutations

Anna S Nam, MD, Kyu-Tae Kim, PhD, Ronan Chaligne, PhD, Franco Izzo, PhD, Chelston Ang, MS, Nathaniel Omans, MS, Alessandro Pastore, Justin Taylor, MD, Alicia Alonso, Wayne Tam, MD PhD, Ronald Hoffman, MD, Joseph Scandura, MDPhD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD, Peter Smibert, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 541.
https://doi.org/10.1182/blood-2018-99-119236
Published: 2018