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Zhengming Chen
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Journal Articles

Subsequent Treatment and Clinical Outcome Following Induction Therapy on a Phase II Study of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL)

Jia Ruan, Evelyn H. Orlando, Alison Moskowitz, Zhengming Chen, Neha Mehta-Shah, Lubomir Sokol, Steven Horwitz, Sarah C. Rutherford, Tejasvi Sahni, Ari M Melnick, Giorgio Inghirami, Leandro Cerchietti, John P. Leonard, Peter Martin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1693.
https://doi.org/10.1182/blood-2024-206606
Published: 2024
Journal Articles

CDK4/6 Inhibition Reverses MEIS2 Inhibition of CRL4 CRBN By Both Disrupting MEIS2-CRBN Association and Opposing Regulation of MEIS2 and CRBN Synthesis That Enhances IMiD Therapy in Multiple Myeloma

Xiangao Huang, David S Jayabalan, Maurizio Di Liberto, Zhengming Chen, Scott Ely, Roger Pearse, Joseph Lane, Gang Lin, Ruben Niesvizky, Selina Chen-Kiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1886.
https://doi.org/10.1182/blood-2024-206115
Published: 2024
Journal Articles

MRD-Driven Time-Limited Therapy of Acalabrutinib and Lenalidomide Plus Rituximab (ALR) or Obinutuzumab (ALO) in Patients with Treatment-Naïve Mantle Cell Lymphoma: Phase 2 Trial Outcomes with MRD and cfDNA Analyses

Jia Ruan, David A. Bond, Bijal D Shah, John N. Allan, Sarah C. Rutherford, Caitlin Gribbin, Zhengming Chen, Brittany Hobbie, Melinda Harbhajan, Tejasvi Sahni, Wayne Tam, Bhavneet Bhinder, Michael Sigouros, Giorgio Inghirami, Selina Chen-Kiang, Olivier Elemento, Kami J. Maddocks, John P. Leonard, Peter Martin
Journal: Blood
Blood (2024) 144 (Supplement 1): 746.
https://doi.org/10.1182/blood-2024-204495
Published: 2024
Journal Articles

T-Cell Signaling Mediates the Epigenetic Priming of Germinal Center B-Cell Plasticity and Stem Functionality

Laurianne Scourzic, Franco Izzo, Lucretia Cucereavii, Matthew Teater, Alexander Polyzos, Christopher Chin, Coraline Mlynarczyk, Ioanna Tsialta, Robert M Myers, Wendy Béguelin, Matthias Stadtfeld, Zhengming Chen, Dan A. Landau, Ari M Melnick, Eftychia Apostolou
Journal: Blood
Blood (2023) 142 (Supplement 1): 2767.
https://doi.org/10.1182/blood-2023-190437
Published: 2023
Journal Articles

Outcomes of Contemporary Novel Agent and Stem Cell Transplantation in Relapsed/Refractory PTCL

Seda S. Tolu, Caitlin Gribbin, Madhav R Seshadri, Zhengming Chen, Evelyn Orlando, Justin Grenet, Rajbir Toor, Alexander Sanjurjo, Adrienne A. Phillips, Tsiporah B. Shore, Peter Martin, John P. Leonard, Barbara Pro, Jennifer E. Amengual, Jia Ruan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1698.
https://doi.org/10.1182/blood-2023-178231
Published: 2023
Journal Articles

Impact of Graft Source [Cord Blood Supported By CD34+ Selected Cells (Haplo-Cord) Vs. Matched Donor] on Transplant Outcomes in Myelofibrosis

Nima Ghalehsari, Zhengming Chen, Sebastian A. Mayer, Ghaith Abu-Zeinah, Tsiporah B. Shore, Ellen K. Ritchie, Richard T. Silver, Andrew I. Schafer, Joseph M. Scandura, Gail J. Roboz, Koen Van Besien, Alexandra Gomez-Arteaga
Journal: Blood
Blood (2023) 142 (Supplement 1): 6953.
https://doi.org/10.1182/blood-2023-185075
Published: 2023
Journal Articles

Improvements in Overall Survival in Older Patients with Mantle Cell Lymphoma Are Driven By Improvements across Multiple Lines of Therapy

Danny Luan, Neela Easwar, Zhengming Chen, Brian K. Link, Yucai Wang, Matthew J. Maurer, Brad S. Kahl, Laura Pinheiro, John P. Leonard, Peter Martin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1664.
https://doi.org/10.1182/blood-2023-184807
Published: 2023
Journal Articles

Patterns of Care and Impact of Initial Treatment in Peripheral T-Cell Lymphoma: Outcome Analysis from the Lymphoma Epidemiology of Outcomes (LEO) and Molecular Epidemiology Resource (MER) Prospective Cohort Study

Jia Ruan, Zhengming Chen, Melissa C. Larson, N. Nora Bennani, Danielle Wallace, Pamela B. Allen, David L Jaye, Jonathon B. Cohen, Luis Enrique Malpica Castillo, Francisco Vega, Giorgio Inghirami, Eric Mou, Carla Casulo, Neha Mehta-Shah, Peter Martin, Matthew J. Maurer, Brad S. Kahl, Izidore S. Lossos, James R. Cerhan, Christopher R. Flowers, Andrew L. Feldman
Journal: Blood
Blood (2023) 142 (Supplement 1): 3079.
https://doi.org/10.1182/blood-2023-180318
Published: 2023
Journal Articles

Rates of Ibrutinib Uptake Among Black Patients with Lymphoma in SEER-Medicare Increased over Time

Danny Luan, Rahma Ibrahim, Zhengming Chen, John P. Leonard, Laura Pinheiro, Peter Martin
Journal: Blood
Blood (2023) 142 (Supplement 1): 7372.
https://doi.org/10.1182/blood-2023-190900
Published: 2023
Journal Articles

PRMT5 supports multiple oncogenic pathways in mantle cell lymphoma

Shelby L. Sloan, Fiona Brown, Mackenzie Long, Christoph Weigel, Shirsha Koirala, Ji-Hyun Chung, Betsy Pray, Lynda Villagomez, Claire Hinterschied, Anuvrat Sircar, JoBeth Helmig-Mason, Alexander Prouty, Eric Brooks, Youssef Youssef, Walter Hanel, Samir Parekh, Wing Keung Chan, Zhengming Chen, Rosa Lapalombella, Lalit Sehgal, Kris Vaddi, Peggy Scherle, Selina Chen-Kiang, Maurizio Di Liberto, Olivier Elemento, Cem Meydan, Jonathan Foox, Daniel Butler, Christopher E. Mason, Robert A. Baiocchi, Lapo Alinari
Journal: Blood
Blood (2023) 142 (10): 887–902.
https://doi.org/10.1182/blood.2022019419
Published: 2023
Includes: Supplemental data
Journal Articles

Multicenter phase 2 study of oral azacitidine (CC-486) plus CHOP as initial treatment for PTCL

Clinical Trials & Observations
Jia Ruan, Alison Moskowitz, Neha Mehta-Shah, Lubomir Sokol, Zhengming Chen, Nikita Kotlov, Grigorii Nos, Maria Sorokina, Vladislav Maksimov, Andrea Sboner, Michael Sigouros, Koen van Besien, Steven Horwitz, Sarah C. Rutherford, Erin Mulvey, Maria V. Revuelta, Jenny Xiang, Alicia Alonso, Ari Melnick, Olivier Elemento, Giorgio Inghirami, John P. Leonard, Leandro Cerchietti, Peter Martin
Journal: Blood
Blood (2023) 141 (18): 2194–2205.
https://doi.org/10.1182/blood.2022018254
Published: 2023
Includes: Supplemental data
Journal Articles

Patterns of Care and Clinical Outcomes in Peripheral T-Cell Lymphomas: The Lymphoma Epidemiology of Outcomes (LEO) and Molecular Epidemiology Resource (LEO-MER) Prospective Cohort Study

Jia Ruan, Melissa C. Larson, Zhengming Chen, N. Nora Bennani, Pamela B. Allen, David L Jaye, Jonathon B. Cohen, Dai Chihara, Francisco Vega, Giorgio Inghirami, Eric Mou, Carla Casulo, Neha Mehta-Shah, Peter Martin, Matthew J. Maurer, Brad S. Kahl, Izidore S. Lossos, Christopher R. Flowers, James R. Cerhan, Andrew L. Feldman
Journal: Blood
Blood (2022) 140 (Supplement 1): 3666–3668.
https://doi.org/10.1182/blood-2022-164988
Published: 2022
Journal Articles

Epigenetic Priming with 5-Azacytidine Prior to Allogeneic Stem Cell Transplantation for Myeloid Malignancies with In Vivo T Cell Depletion: Results of a Phase II Trial

Mohammad Alhomoud, Usama Gergis, Adrienne A. Phillips, Jingmei Hsu, Zhengming Chen, Alexandra Gomez-Arteaga, Tsiporah B. Shore, Joseph Scandura, Koen Van Besien, Sebastian A. Mayer
Journal: Blood
Blood (2022) 140 (Supplement 1): 7583–7584.
https://doi.org/10.1182/blood-2022-170097
Published: 2022
Journal Articles

Phase 2 Trial of Acalabrutinib-Lenalidomide-Rituximab (ALR) with Real-Time Monitoring of MRD in Patients with Treatment-Naïve Mantle Cell Lymphoma

Jia Ruan, John P. Leonard, Gui Zhen Chen, Zhengming Chen, John N. Allan, Sarah C. Rutherford, Brittany Hobbie, Katie Greig, Amelyn Rodriguez, Wayne Tam, David A. Bond, Bijal D. Shah, Kami J. Maddocks, Bhavneet Binder, Giorgio Inghirami, Olivier Elemento, Selina Chen-Kiang, Peter Martin
Journal: Blood
Blood (2022) 140 (Supplement 1): 175–177.
https://doi.org/10.1182/blood-2022-158656
Published: 2022
Journal Articles

Oncogenic role of the SOX9-DHCR24-cholesterol biosynthesis axis in IGH-BCL2 + diffuse large B-cell lymphomas

Yajie Shen, Jingqi Zhou, Kui Nie, Shuhua Cheng, Zhengming Chen, Wenhan Wang, Weiqing Wei, Daiji Jiang, Zijing Peng, Yizhuo Ren, Yirong Zhang, Qiuju Fan, Kristy L. Richards, Yitao Qi, Jinke Cheng, Wayne Tam, Jiao Ma
Journal: Blood
Blood (2022) 139 (1): 73–86.
https://doi.org/10.1182/blood.2021012327
Published: 2022
Includes: Supplemental data
Journal Articles

FOXO1 Dependent Transcription Network Is a Targetable Vulnerability of Mantle Cell Lymphoma

Ja-Young Jang, Inah Hwang, Heng Pan, Michael Kluk, Jun Yao, Xiangao Huang, Maurizio Di Liberto, Zhengming Chen, Karla V Ballman, Lewis C Cantley, Giorgio Inghirami, Olivier Elemento, Robert Baiocchi, Selina Chen-Kiang, Sandro Belvedere, Hongwu Zheng, Jihye Paik
Journal: Blood
Blood (2021) 138 (Supplement 1): 30.
https://doi.org/10.1182/blood-2021-153378
Published: 2021
Journal Articles

Impact of Peri-Transplant Molecular Mutations on Outcomes of AML Patients Undergoing Fludarabine/Melphalan Conditioned Allogeneic Stem Cell Transplant

Mateo Mejia Saldarriaga, Yassine Tahri, Sangmin Lee, Zhengming Chen, Tsiporah B. Shore, Danielle Guarneri, Sebastian A. Mayer, Adrienne A. Phillips, Alexandra Gomez-Arteaga, Pinkal Desai, Ellen Ritchie, Michael B. Samuel, Gail J. Roboz, Koen van Besien, Jingmei Hsu
Journal: Blood
Blood (2021) 138 (Supplement 1): 4833.
https://doi.org/10.1182/blood-2021-149297
Published: 2021
Journal Articles

High Rates of Remission with the Initial Treatment of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL): Clinical Outcomes and Biomarker Analysis of a Multi-Center Phase II Study

Jia Ruan, Alison J. Moskowitz, Neha Mehta-Shah, Lubomir Sokol, Zhengming Chen, Riyaad Rahim, Wei Song, Nikita Kotlov, Grigorii Nos, Vladislav Maksimov, Maria Victoria Revuelta, Andrea Sboner, Michael Sigouros, Koen van Besien, Steven M. Horwitz, Sarah C. Rutherford, Erin C. Mulvey, Morton Coleman, Ari Melnick, Olivier Elemento, Giorgio Inghirami, John P. Leonard, Peter Martin, Leandro Cerchietti
Journal: Blood
Blood (2021) 138 (Supplement 1): 138.
https://doi.org/10.1182/blood-2021-145495
Published: 2021
Journal Articles

BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells

Kimihito C. Kawabata, Hongliang Zong, Cem Meydan, Sarah Wyman, Bas J. Wouters, Mayumi Sugita, Srinjoy Goswami, Michael Albert, Winnie Yip, Gail J. Roboz, Zhengming Chen, Ruud Delwel, Martin Carroll, Christopher E. Mason, Ari Melnick, Monica L. Guzman
Journal: Blood
Blood (2021) 137 (6): 812–825.
https://doi.org/10.1182/blood.2019001745
Published: 2021
Includes: Supplemental data
Journal Articles

A Phase I Study of Selinexor and R-ICE in Patients with Relapsed/Refractory Aggressive B-Cell Lymphomas

Sarah C. Rutherford, MD, John N. Allan, MD, Jia Ruan, MD PhD, Richard R. Furman, MD, Kristy Richards, MD PhD, Amelyn Rodriguez, BSN, RN, OCN, Kseniya Gololobova, Arcania Garcia, Leandro Cerchietti, MD, Rossella Marullo, MDPhD, Zhengming Chen, PhD MPH, MS, Jennifer Santamala, PharmD, Tsiporah B. Shore, MD, Adrienne A. Phillips, MD MPH, Sebastian Mayer, MD, Jingmei Hsu, MD, Usama Gergis, MD, Silvia Senese, Trisha Ali-Shaw, Riyaad Rahim, Koen van Besien, MD PhD, John P. Leonard, MD, Peter Martin, FRCPC, MD MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-134699
Published: 2020