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Journal Articles

Association of Sex, Race and Ethnicity with Clinical Characteristics and Survival Outcomes of Mantle Cell Lymphoma: A National Cancer Database Study

Jacqueline F. Wang, Jihao Zhou, Reema K. Tawfiq, Han W. Tun, Javier L. Munoz, Jonas Paludo, Muhamad Alhaj Moustafa, Steven R. Hwang, Izel Okcu, Catherine S. Diefenbach, Jia Ruan, Peter Martin, Thomas M. Habermann, Thomas E. Witzig, Grzegorz S. Nowakowski, Yucai Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1637.
https://doi.org/10.1182/blood-2024-204268
Published: 2024
Journal Articles

Disrupting IL10 Signaling Overcomes Compound Copy Number Variation-Driven Clinical Resistance to CDK4/6 and BTK Inhibition in Mantle Cell Lymphoma

Maurizio Di Liberto, Yang Hu, Xiangao Huang, Giorgio Inghirami, Kevin Wang, Christina Y. Lee, Kami J. Maddocks, Kristie A. Blum, Jia Ruan, John P. Leonard, Nancy L. Bartlett, Peter Martin, Olivier Elemento, Selina Chen-Kiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 831.
https://doi.org/10.1182/blood-2024-209415
Published: 2024
Journal Articles

MRD-Driven Time-Limited Therapy of Acalabrutinib and Lenalidomide Plus Rituximab (ALR) or Obinutuzumab (ALO) in Patients with Treatment-Naïve Mantle Cell Lymphoma: Phase 2 Trial Outcomes with MRD and cfDNA Analyses

Jia Ruan, David A. Bond, Bijal D Shah, John N. Allan, Sarah C. Rutherford, Caitlin Gribbin, Zhengming Chen, Brittany Hobbie, Melinda Harbhajan, Tejasvi Sahni, Wayne Tam, Bhavneet Bhinder, Michael Sigouros, Giorgio Inghirami, Selina Chen-Kiang, Olivier Elemento, Kami J. Maddocks, John P. Leonard, Peter Martin
Journal: Blood
Blood (2024) 144 (Supplement 1): 746.
https://doi.org/10.1182/blood-2024-204495
Published: 2024
Journal Articles

Enhancing Diagnostic and Prognostic Strategies in Secondary HLH: Insights from the Weill-Cornell Medicine Experience

Justin D. Kaner, Danny Luan, Franco Castillo Tokumori, John-William Sidhom, Jose Fernandez-Rengifo, Samantha Gerson, Matthew Whitcomb, Molly Vallon, Ellen K. Ritchie, Michael Samuel, Jonathan Canaani, Michal Bar-Natan, Erin Mulvey, Peter Martin, Pinkal Desai, John N. Allan, Richard R. Furman, Sarah C. Rutherford, Jia Ruan, Gail J. Roboz
Journal: Blood
Blood (2024) 144 (Supplement 1): 5379.
https://doi.org/10.1182/blood-2024-210134
Published: 2024
Journal Articles

Subsequent Treatment and Clinical Outcome Following Induction Therapy on a Phase II Study of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL)

Jia Ruan, Evelyn H. Orlando, Alison Moskowitz, Zhengming Chen, Neha Mehta-Shah, Lubomir Sokol, Steven Horwitz, Sarah C. Rutherford, Tejasvi Sahni, Ari M Melnick, Giorgio Inghirami, Leandro Cerchietti, John P. Leonard, Peter Martin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1693.
https://doi.org/10.1182/blood-2024-206606
Published: 2024
Journal Articles

Real World First-Line Treatment Strategies and Outcomes in TP53 Mutated and Unmutated Mantle Cell Lymphoma

Jie Wang, Jihao Zhou, Yucai Wang, Javier L. Munoz, Kevin G. Shim, Muhamad Alhaj Moustafa, Firas Baidoun, Kaitlin Annunzio, Narendranath Epperla, Michael McLane, Yasmin H. Karimi, Binh Luu, Stephen E Spurgeon, Cheryl Chang, Zihan Wan, Diamone Gathers, Emily R. King, Marcus P. Watkins, Nancy L. Bartlett, Christine E. Ryan, Genevieve M Gerhard, Philippe Armand, Ann S. LaCasce, Vedha Vaddaraju, Danielle S Wallace, Vaishalee P Kenkre, Chase Junge, Natalie Grover, Jorge A Florindez, Reem Karmali, Alexander V. Stanisic, Chen Zhang, Parameswaran Venugopal, Grace Ying, Caitlin Gribbin, Jia Ruan, Navika D Shukla, Sonali M. Smith, Viktoriya Zelikson, Michael E. Williams, Stefan K. Barta, Omar Elghawy, Jake Schade, Rohini Navalekar, Matthew Matasar, Andrew M Evens, Alexey V. Danilov, Timothy S. Fenske
Journal: Blood
Blood (2024) 144 (Supplement 1): 4406.
https://doi.org/10.1182/blood-2024-194601
Published: 2024
Journal Articles

Impact of Novel Therapies (NTs) on Real-World (RW) Clinical Outcomes of Patients (pts) with Relapsed/Refractory (RR) Mantle-Cell Lymphoma (MCL) By Race/Ethnicity and TP53 Mutation Status

Tycel J. Phillips, Alexey V. Danilov, Jia Ruan, Krish Patel, Anita Kumar, Yucai Wang, Gregory A. Maglinte, Erlene Seymour, Manali Kamdar
Journal: Blood
Blood (2024) 144 (Supplement 1): 5097.
https://doi.org/10.1182/blood-2024-204269
Published: 2024
Journal Articles

Zanubrutinib and Venetoclax As Initial Therapy for CLL/SLL with Obinutuzumab Triplet Consolidation in Patients with Minimal Residual Disease Positivity (BruVenG)

John N. Allan, Daniel Helbig, Erin Mulvey, Sarah Nazir, Sandra Stewart, Melissa L. Lapinta, Sarah C. Rutherford, Jia Ruan, John P. Leonard, Peter Martin, Richard R. Furman
Journal: Blood
Blood (2023) 142 (Supplement 1): 3285.
https://doi.org/10.1182/blood-2023-174465
Published: 2023
Journal Articles

Outcomes of Contemporary Novel Agent and Stem Cell Transplantation in Relapsed/Refractory PTCL

Seda S. Tolu, Caitlin Gribbin, Madhav R Seshadri, Zhengming Chen, Evelyn Orlando, Justin Grenet, Rajbir Toor, Alexander Sanjurjo, Adrienne A. Phillips, Tsiporah B. Shore, Peter Martin, John P. Leonard, Barbara Pro, Jennifer E. Amengual, Jia Ruan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1698.
https://doi.org/10.1182/blood-2023-178231
Published: 2023
Journal Articles

Harnessing Btki Therapy By CDK4/6i Control of T Effector Memory Cells and T Cell Surveillance in Mantle Cell Lymphoma

Maurizio Di Liberto, Yang Hu, Xiangao Huang, Giorgio Inghirami, Kevin Wang, Christina Lee, Kami J. Maddocks, Kristie A. Blum, Jia Ruan, John P. Leonard, Nancy L. Bartlett, Peter Martin, Olivier Elemento, Selina Chen-Kiang
Journal: Blood
Blood (2023) 142 (Supplement 1): 50.
https://doi.org/10.1182/blood-2023-190308
Published: 2023
Journal Articles

Patterns of Care and Impact of Initial Treatment in Peripheral T-Cell Lymphoma: Outcome Analysis from the Lymphoma Epidemiology of Outcomes (LEO) and Molecular Epidemiology Resource (MER) Prospective Cohort Study

Jia Ruan, Zhengming Chen, Melissa C. Larson, N. Nora Bennani, Danielle Wallace, Pamela B. Allen, David L Jaye, Jonathon B. Cohen, Luis Enrique Malpica Castillo, Francisco Vega, Giorgio Inghirami, Eric Mou, Carla Casulo, Neha Mehta-Shah, Peter Martin, Matthew J. Maurer, Brad S. Kahl, Izidore S. Lossos, James R. Cerhan, Christopher R. Flowers, Andrew L. Feldman
Journal: Blood
Blood (2023) 142 (Supplement 1): 3079.
https://doi.org/10.1182/blood-2023-180318
Published: 2023
Journal Articles

A National Cancer Database Study of Survival Trends in Patients with Mantle Cell Lymphoma Stratified By Age Group

Jacqueline F. Wang, Jihao Zhou, Steven R Hwang, Catherine S Diefenbach, Jia Ruan, Peter Martin, Jonas Paludo, Javier L. Munoz, Stephen M Ansell, Thomas E. Witzig, Thomas M. Habermann, James R. Cerhan, Grzegorz S. Nowakowski, Yucai Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1663.
https://doi.org/10.1182/blood-2023-179611
Published: 2023
Journal Articles

Multicenter Study of Mantle Cell Lymphoma Outcomes Following First-Line Bendamustine-Rituximab and Second-Line Bruton's Tyrosine Kinase Inhibitor Therapy

Yucai Wang, Melissa C. Larson, Steven R. Hwang, Anita Kumar, Ashlee Joseph, Brian T. Hill, Taylor R. Brooks, David A. Bond, Kami J. Maddocks, Alexey Danilov, Christine McCarthy, Jia Ruan, Imran A. Nizamuddin, Brad S. Kahl, Natalie S. Grover, Nazneen B. Khan, Evguenia Ouchveridze, Aung M. Tun, Philip Young, Craig A. Portell, Zoey I. Harris, Javier L. Munoz, Patrick M. Reagan, Georgio Pongas, Izidore S. Lossos, Christine E. Ryan, Reid W. Merryman, Firas Baidoun, Muhamad Alhaj Moustafa, Drew Gerber, Sabarish R. Ayyappan, Brian K. Link, Arash Velayati, Irl Brian Greenwell, Lauren G Banaszak, Priyanka A Pophali, Anthony C. Stack, Marcus R. Messmer, Mayur Narkhede, Amitkumar N. Mehta, Preetesh Jain, Michael L. Wang, Tamara K. Moyo, Nilanjan Ghosh, Rahul S. Bhansali, Stefan K. Barta, Manali K. Kamdar, Jacob Anna, Alexander V. Stanisic, Reem Karmali, Laveniya Kugathasan, Diego Villa, Matthew J. Maurer, James R. Cerhan, Jonathon B. Cohen, Peter Martin
Journal: Blood
Blood (2023) 142 (Supplement 1): 300.
https://doi.org/10.1182/blood-2023-182942
Published: 2023
Journal Articles

Multicenter phase 2 study of oral azacitidine (CC-486) plus CHOP as initial treatment for PTCL

Clinical Trials & Observations
Jia Ruan, Alison Moskowitz, Neha Mehta-Shah, Lubomir Sokol, Zhengming Chen, Nikita Kotlov, Grigorii Nos, Maria Sorokina, Vladislav Maksimov, Andrea Sboner, Michael Sigouros, Koen van Besien, Steven Horwitz, Sarah C. Rutherford, Erin Mulvey, Maria V. Revuelta, Jenny Xiang, Alicia Alonso, Ari Melnick, Olivier Elemento, Giorgio Inghirami, John P. Leonard, Leandro Cerchietti, Peter Martin
Journal: Blood
Blood (2023) 141 (18): 2194–2205.
https://doi.org/10.1182/blood.2022018254
Published: 2023
Includes: Supplemental data
Journal Articles

Patterns of Care and Clinical Outcomes in Peripheral T-Cell Lymphomas: The Lymphoma Epidemiology of Outcomes (LEO) and Molecular Epidemiology Resource (LEO-MER) Prospective Cohort Study

Jia Ruan, Melissa C. Larson, Zhengming Chen, N. Nora Bennani, Pamela B. Allen, David L Jaye, Jonathon B. Cohen, Dai Chihara, Francisco Vega, Giorgio Inghirami, Eric Mou, Carla Casulo, Neha Mehta-Shah, Peter Martin, Matthew J. Maurer, Brad S. Kahl, Izidore S. Lossos, Christopher R. Flowers, James R. Cerhan, Andrew L. Feldman
Journal: Blood
Blood (2022) 140 (Supplement 1): 3666–3668.
https://doi.org/10.1182/blood-2022-164988
Published: 2022
Journal Articles

Phase 2 Trial of Acalabrutinib-Lenalidomide-Rituximab (ALR) with Real-Time Monitoring of MRD in Patients with Treatment-Naïve Mantle Cell Lymphoma

Jia Ruan, John P. Leonard, Gui Zhen Chen, Zhengming Chen, John N. Allan, Sarah C. Rutherford, Brittany Hobbie, Katie Greig, Amelyn Rodriguez, Wayne Tam, David A. Bond, Bijal D. Shah, Kami J. Maddocks, Bhavneet Binder, Giorgio Inghirami, Olivier Elemento, Selina Chen-Kiang, Peter Martin
Journal: Blood
Blood (2022) 140 (Supplement 1): 175–177.
https://doi.org/10.1182/blood-2022-158656
Published: 2022
Journal Articles

Claiming the mantle of the brain

Jia Ruan
Journal: Blood
Blood (2022) 140 (17): 1835–1836.
https://doi.org/10.1182/blood.2022017285
Published: 2022
Journal Articles

A phase 2 biomarker-driven study of ruxolitinib demonstrates effectiveness of JAK/STAT targeting in T-cell lymphomas

Clinical Trials & Observations
Alison J. Moskowitz, Paola Ghione, Eric Jacobsen, Jia Ruan, Jonathan H. Schatz, Sarah Noor, Patricia Myskowski, Santosha Vardhana, Nivetha Ganesan, Helen Hancock, Theresa Davey, Leslie Perez, Sunyoung Ryu, Alayna Santarosa, Jack Dowd, Obadi Obadi, Lauren Pomerantz, Nancy Yi, Samia Sohail, Natasha Galasso, Rachel Neuman, Brielle Liotta, William Blouin, Jeeyeon Baik, Mark B. Geyer, Ariela Noy, David Straus, Priyadarshini Kumar, Ahmet Dogan, Travis Hollmann, Esther Drill, Jurgen Rademaker, Heiko Schoder, Giorgio Inghirami, David M. Weinstock, Steven M. Horwitz
Journal: Blood
Blood (2021) 138 (26): 2828–2837.
https://doi.org/10.1182/blood.2021013379
Published: 2021
Includes: Supplemental data
Journal Articles

High Rates of Remission with the Initial Treatment of Oral Azacitidine Plus CHOP for Peripheral T-Cell Lymphoma (PTCL): Clinical Outcomes and Biomarker Analysis of a Multi-Center Phase II Study

Jia Ruan, Alison J. Moskowitz, Neha Mehta-Shah, Lubomir Sokol, Zhengming Chen, Riyaad Rahim, Wei Song, Nikita Kotlov, Grigorii Nos, Vladislav Maksimov, Maria Victoria Revuelta, Andrea Sboner, Michael Sigouros, Koen van Besien, Steven M. Horwitz, Sarah C. Rutherford, Erin C. Mulvey, Morton Coleman, Ari Melnick, Olivier Elemento, Giorgio Inghirami, John P. Leonard, Peter Martin, Leandro Cerchietti
Journal: Blood
Blood (2021) 138 (Supplement 1): 138.
https://doi.org/10.1182/blood-2021-145495
Published: 2021
Journal Articles

Terraflow, a New High Parameter Data Analysis Tool, Reveals Systemic T-Cell Exhaustion and Dysfunctional Cytokine Production in Classical Hodgkin Lymphoma

Dan Freeman, Linda Lam, Tri Li, Jason Alexandre, Bruce G. Raphael, David Kaminetzky, Jia Ruan, Pratip Chattopadhyay, Catherine S. Diefenbach
Journal: Blood
Blood (2021) 138 (Supplement 1): 3516.
https://doi.org/10.1182/blood-2021-149154
Published: 2021