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Anna S Nam
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Journal Articles

Patient-Derived Models of Clonal Hematopoiesis Point to Cell-Intrinsic and -Extrinsic Contributions to Clonal Dominance and Lineage Imbalances

Mareike Peters, Jiajun Xie, Sergiu Pasca, Hamzah Kharabsheh, Anna S Nam, Lukasz P. Gondek, Gabriel Ghiaur
Journal: Blood
Blood (2024) 144 (Supplement 1): 1294.
https://doi.org/10.1182/blood-2024-208399
Published: 2024
Journal Articles

Hallmarks of Transcriptional Heterogeneity in Human Hematopoietic Stem Cells across 382 Donors

Sayyam Shah, Murtaza S. Nagree, Chhiring Lama, Anna S. Nam, Andy G.X. Zeng, Stephanie Z Xie, John E. Dick
Journal: Blood
Blood (2024) 144 (Supplement 1): 1281.
https://doi.org/10.1182/blood-2024-212079
Published: 2024
Journal Articles

KRAS G12D Specific Inhibitors Relieve Erythroid Differentiation Block and Modulate Inflammatory Pathways at the Single Cell Level in Myeloid Malignancies

Leah Kravets, Mirca S. Saurty-Seerunghen, Divij Verma, Ariel Fromowitz, Srabani Sahu, Bradley Rockwell, Olivia Sakaguchi, Swathi Narayanagari, Shanisha Gordon Mitchell, Milagros Carbajal, Srinivas Aluri, Jingli Wang, Lindsay Lafave, Marina Konopleva, Anna S. Nam, Amit Verma
Journal: Blood
Blood (2024) 144 (Supplement 1): 326.
https://doi.org/10.1182/blood-2024-208924
Published: 2024
Journal Articles

Topic Modeling of Genotyping of Transcriptomes Reveals Collaboration between BTK C481S -Mutant and Wild Type Cells in Btki-Resistant Chronic Lymphocytic Leukemia

Ramon Massoni-Badosa, Joshua S. Schiffman, Barun Pradhan, Rebecca M. Murray, Andrew H. Lipsky, Debra Van Egeren, Danny Luan, Shirley Chen, Ronan Chaligne, Kai Beattie, Alyssa Indart, Nada Chraiki, Neville Dusaj, Erica B. Bhavsar, Chelston Ang, Anna S. Nam, Federico Gaiti, Paulina Chamely, Nathaniel D. Omans, Preeti Trisal, Anita K. Gandhi, Kyu-Tae Kim, Rafael Schulman, Franco Izzo, Gavriel Mullokandov, Chingiz Underbayev, Jan A. Burger, Adrian Wiestner, Elisa Ten Hacken, John N. Allan, Jennifer A. Woyach, Richard R. Furman, Dan A. Landau
Journal: Blood
Blood (2024) 144 (Supplement 1): 4610.
https://doi.org/10.1182/blood-2024-205727
Published: 2024
Journal Articles

Classic Hodgkin Lymphomas Display Neuronal-Glial Lineage Transdifferentiation

Mirca S. Saurty-Seerunghen, Sara Moein, Tsega-Ab Abera, Xiaotian Sun, Sohani Sharma, Chhiring Lama, Mansi Totwani, Shira Rosenberg, Qi Gao, Neelang Parghi, Amy Chadburn, Kui Nie, Vicenta Trujillo Alonso, Elizabeth Bier, Jenny Xiang, Ethel Cesarman, Wayne Tam, Mikhail Roshal, Lisa Giulino Roth, Anna S Nam
Journal: Blood
Blood (2023) 142 (Supplement 1): 715.
https://doi.org/10.1182/blood-2023-189533
Published: 2023
Journal Articles

Single-Cell Multi-Omics Reveals That Pegylated Interferon-Alfa Treatment Differentially Redirects Mutated and Wildtype Hematopoietic Cell Differentiation Trajectories in CALR- mutated Essential Thrombocythemia (ET) Patients

Shira Rosenberg, Andrea Kubas-Meyer, Neelang Parghi, Nathaniel D. Omans, Neville Dusaj, Paulina Chamely, Eleni Mimitou, Amylou C. Dueck, Heidi E. Kosiorek, Rona Singer Weinberg, Peter Smibert, Ronan Chaligne, Dan A. Landau, Ronald Hoffman, Anna S Nam
Journal: Blood
Blood (2021) 138 (Supplement 1): 57.
https://doi.org/10.1182/blood-2021-150745
Published: 2021
Journal Articles

Single-Cell Multi-Omics in Human Clonal Hematopoiesis Reveals That DNMT3A R882 Mutations Perturb Early Progenitor States through Selective Hypomethylation

Anna S Nam, MD, Neville Dusaj, MS, Franco Izzo, PhD, Rekha Murali, MS, Tarek H Mouhieddine, MD, Robert M Myers, Jesus Sotelo, Salima Benbarche, PhD, Federico Gaiti, PhD, Sabrin Tahri, MD MSc, Omar Abdel-Wahab, MD, Irene M. Ghobrial, MD, Ronan Chaligne, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-142574
Published: 2020
Journal Articles

Single-Cell Multi-Omics Reveals Distinct Paths to Survival of Admixed BTK C481 Mutant Vs. Wild-Type Cells in Clinically Progressing Chronic Lymphocytic Leukemia

Andrew Lipsky, MD, Danny Luan, MPH, Shirley Chen, BSc, Ronan Chaligne, PhD, Neville Dusaj, MS, Erica B Bhavsar, BS, Chelston Ang, MS, Anna S Nam, MD, Federico Gaiti, PhD, Paulina Chamely, MSc, Nathaniel D. Omans, MS, Preeti Trisal, MS, Anita K Gandhi, PhD, Kyu-Tae Kim, PhD, Rafael Schulman, BS, Joshua S. Schiffman, PhD, Franco Izzo, PhD, Gregory Mullokandov, MD PhD, Chingiz Underbayev, MD PhD, Adrian Wiestner, MD PhD, John N. Allan, MD, Richard R. Furman, MD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–42.
https://doi.org/10.1182/blood-2020-138374
Published: 2020
Journal Articles

High Throughput Droplet Single-Cell Genotyping of Transcriptomes (GoT) Reveals the Cell Identity Dependency of the Transcriptional Output of Somatic Mutations

Anna S Nam, MD, Kyu-Tae Kim, PhD, Ronan Chaligne, PhD, Franco Izzo, PhD, Chelston Ang, MS, Nathaniel Omans, MS, Alessandro Pastore, Justin Taylor, MD, Alicia Alonso, Wayne Tam, MD PhD, Ronald Hoffman, MD, Joseph Scandura, MDPhD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD, Peter Smibert, PhD, Dan A. Landau, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 541.
https://doi.org/10.1182/blood-2018-99-119236
Published: 2018
Journal Articles

Assessing the Utility of Immunoglobulin and T Cell Receptor Gene Rearrangement Studies for Cerebrospinal Fluid Specimens

Anna S Nam, MD, Amy Chadburn, MD, Wayne Tam, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4145.
https://doi.org/10.1182/blood.V130.Suppl_1.4145.4145
Published: 2017
Journal Articles

Exploring the Tumor Clonal Dynamics between Diffuse Large B-Cell Lymphomas and Bone Marrow Involvement By Deep Immunoglobulin Heavy Chain VDJ Sequencing

Anna S Nam, MD, Jiao Ma, PhD, Ayako Miyaguchi, PhD, David Redmond, Kui Nie, PhD, Olivier Elemento, PhD, Wayne Tam, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2737.
https://doi.org/10.1182/blood.V130.Suppl_1.2737.2737
Published: 2017
Journal Articles

An intrasinusoidal extracavitary variant of primary effusion lymphoma

Anna S. Nam, Wayne Tam
Journal: Blood
Blood (2017) 130 (6): 836.
https://doi.org/10.1182/blood-2017-04-780593
Published: 2017