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Journal Articles

PSAT1 Suppression Drives a Targetable Serine Dependence in AML

Ilias Sinanidis, Panagiotis Tsakiroglou, Rebecca Foertsch, Julia Gondek, Benjamin Dubner, InYoung Choi, Bogdan Paun, Liang Zhao, Everett Stone, George Georgiou, Gabriel Ghiaur, William Brian Dalton

Blood (2024) 144 (Supplement 1): 1383.

https://doi.org/10.1182/blood-2024-211885

Published: 2024

Journal Articles

Patient-Derived Models of Clonal Hematopoiesis Point to Cell-Intrinsic and -Extrinsic Contributions to Clonal Dominance and Lineage Imbalances

Mareike Peters, Jiajun Xie, Sergiu Pasca, Hamzah Kharabsheh, Anna S Nam, Lukasz P. Gondek, Gabriel Ghiaur

Blood (2024) 144 (Supplement 1): 1294.

https://doi.org/10.1182/blood-2024-208399

Published: 2024

Journal Articles

Clonal Dissection of MDS and Secondary AML Resolves Shared Splicing Neoantigens and Mechanistic Underpinnings of Hypomethylating Agent Therapeutic Response

Xuan Zhang, Guangyuan Li, Anna Oliverio, Jennifer VanOudenhove, Amy E. DeZern, Gabriel Ghiaur, Stephanie Halene, H. Leighton Grimes, Nathan Salomonis

Blood (2024) 144 (Supplement 1): 1810.

https://doi.org/10.1182/blood-2024-211099

Published: 2024

Journal Articles

Decitabine Synergizes with Replication Checkpoint Inhibitors in TP53 -Mutated Acute Myeloid Leukemia

Clifford M. Csizmar, Antoine N. Saliba, Kevin L. Peterson, Xue Wei Meng, B. Douglas Smith, Gabriel Ghiaur, Mrinal M. Patnaik, Scott H. Kaufmann

Blood (2024) 144 (Supplement 1): 5782.

https://doi.org/10.1182/blood-2024-208583

Published: 2024

Journal Articles

Efficacy and Tolerability of Blinatumomab in Clinical Trial Ineligible Patients with CD19+ Leukemias

John Preston Claiborne, Daniel Li, B. Douglas Smith, Mark J. Levis, Ivana Gojo, Amy E. DeZern, Alexander J. Ambinder, Tania Jain, Gabrielle T. Prince, Lukasz P. Gondek, Theodoros Karantanos, Gabriel Ghiaur, William Brian Dalton, Jonathan Allen Webster

Blood (2024) 144 (Supplement 1): 5904.

https://doi.org/10.1182/blood-2024-207608

Published: 2024

Journal Articles

Acute Lymphoblastic Leukemia (ALL) Outcomes after Allogeneic Blood or Marrow Transplantation (alloBMT) with High-Dose Post-Transplantation Cyclophosphamide (PTCy) in the Era of More Effective Pre-Transplant Therapy

Blood (2024) 144 (Supplement 1): 3551.

https://doi.org/10.1182/blood-2024-212141

Published: 2024

Journal Articles

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias

Rahul S. Vedula, Hannah Q. Karp, Jeremy Koob, Felicia Lim, Jacqueline S. Garcia, Eric S. Winer, Marlise R. Luskin, Gabriel Ghiaur, Annette S. Kim, Lan W. Beppu, Olga Sala-Torra, Jerald Radich, Jonathan Gootenberg, Omar Abudayyeh, Feng Zhang, R. Coleman Lindsley

Blood (2024) 144 (12): 1290–1299.

https://doi.org/10.1182/blood.2023022908

Published: 2024

Includes: Supplemental data

Journal Articles

CYP26 Activity Maintains the Bone Marrow Niche and Stem Cell Homeostasis

Teodora Diana Supeanu, Cristian Moldovan, Laura Palau, Sergiu Pasca, Patric Teodorescu, Lukasz P. Gondek, Gabriel Ghiaur

Blood (2023) 142 (Supplement 1): 2702.

https://doi.org/10.1182/blood-2023-189136

Published: 2023

Journal Articles

Outcomes of Patients with TP53 -Mutated Myeloid Neoplasms (TP53-MN) and the Role of Allogenic Blood or Marrow Transplantation (alloBMT)

Sergiu Pasca, Saurav D. Haldar, Alexander J. Ambinder, Jonathan Webster, Tania Jain, William Brian Dalton, Gabrielle T. Prince, Gabriel Ghiaur, Amy E. DeZern, Ivana Gojo, Jonathan Allen Webster, Cory Schulz, Kristin Stokvis, Mark J. Levis, Richard J. Jones, Lukasz P. Gondek

Blood (2022) 140 (Supplement 1): 10629–10631.

https://doi.org/10.1182/blood-2022-169148

Published: 2022

Journal Articles

CCRL2 Promotes Cytokine-Regulated Growth of Erythroleukemia Cells

Theodoros Karantanos, Christopher Esteb, Patric Teodorescu, Brandy Perkins, Ilias Christodoulou, Stamatia Vorri, Trivikram Rajkhowa, William Brian Dalton, Gabriel Ghiaur, Richard J. Jones

Blood (2022) 140 (Supplement 1): 5866–5867.

https://doi.org/10.1182/blood-2022-159538

Published: 2022

Journal Articles

Allogeneic Blood or Marrow Transplantation (AlloBMT) with High-Dose Post-Transplantation Cyclophosphamide (PTCy) for Acute Lymphoblastic Leukemia (ALL) in Patients Aged ≥ 55: Best Results in B ALL in First Remission (CR1) with Reduced-Intensity Conditioning (RIC)

Blood (2022) 140 (Supplement 1): 4813–4815.

https://doi.org/10.1182/blood-2022-171038

Published: 2022

Journal Articles

Single-Cell Multiomics Reveal Hypomethylating Agent Partially Restores Hematopoiesis in a LR-MDS Patient at the Cost of Leukemic Transformation

Xuan Zhang, Baobao (Annie) Song, Mohammad Daud Khan, Kyle Ferchen, Chih-Hsing Chou, Guangyuan Li, Amy E. DeZern, Gabriel Ghiaur, Stephanie Halene, Nathan Salomonis, H. Leighton Grimes

Blood (2022) 140 (Supplement 1): 9759–9760.

https://doi.org/10.1182/blood-2022-169300

Published: 2022

Journal Articles

Gemtuzumab Ozogamicin for Cytoreduction in Hyperleukocytosis

Matthew Scarlotta, Jonathan Webster, Matthew Newman, Cory Schulz, Kristin Stokvis, Alexander J. Ambinder, Tania Jain, William Brian Dalton, Lukasz P. Gondek, Gabrielle T. Prince, Gabriel Ghiaur, Christopher S. Hourigan, Amy E. DeZern, Ivana Gojo, Jonathan Allen Webster, Mark J. Levis

Blood (2022) 140 (Supplement 1): 11747–11748.

https://doi.org/10.1182/blood-2022-160300

Published: 2022

Journal Articles

PIM Inhibition By SEL24/MEN1703 Combines Synergistically with Gilteritinib in FLT3-ITD Preclinical Models of Acute Myeloid Leukemia

Daniela Bellarosa, Sonia Zicari, Giuseppe Merlino, Alessio Fiascarelli, Diego Bisignano, Francesco Belli, Clelia Irrissuto, Simone Talucci, Maria Luisa Iannitto, Mario Bigioni, Alessandro Bressan, Krzysztof Brzózka, Gabriel Ghiaur, Monica Binaschi

Blood (2022) 140 (Supplement 1): 3090–3091.

https://doi.org/10.1182/blood-2022-168491

Published: 2022

Journal Articles

CD38 Is a Key Regulator of Tumor Growth By Modulating the Metabolic Signature of Malignant Plasma Cells

Ruxandra Maria Irimia, Margo Brooke Gerke, Maya Thakar, Zhihong Ren, Eric Helmenstine, Philip H. Imus, Gabriel Ghiaur, Robert Leone, Christian B. Gocke

Blood (2021) 138 (Supplement 1): 2652.

https://doi.org/10.1182/blood-2021-148693

Published: 2021

Journal Articles

Single-Cell Transcriptomic and Proteomic Analysis of Acute Myeloid Leukemia (AML) Patients with Abnormalities on Chromosome 7

Gege Gui, Meghali Goswami, Chidera Nosiri, Laura W. Dillon, Gabriel Ghiaur, Rena Xian, Pradeep Dagur, Philip McCoy, Christopher S. Hourigan

Blood (2021) 138 (Supplement 1): 1289.

https://doi.org/10.1182/blood-2021-152669

Published: 2021

Journal Articles

Response Prediction to Isocitrate Dehydrogenase (IDH) Inhibitors in Patients with IDH1 - or IDH2 -Mutated Acute Myeloid Leukemia Using Clinical and Genomic Data

Blood (2021) 138 (Supplement 1): 1285.

https://doi.org/10.1182/blood-2021-147099

Published: 2021

Journal Articles

Nonmyeloablative Allogeneic Transplantation in First Remission for Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia with Post-Transplantation Cyclophosphamide: Outcomes By Receipt of Pre-Transplant Blinatumomab

Blood (2021) 138 (Supplement 1): 1846.

https://doi.org/10.1182/blood-2021-153750

Published: 2021

Journal Articles

Arsenic Trioxide Reprograms the Bone-Marrow Microenvironment to Sensitize Minimal Residual Disease in Acute Myeloid Leukemia

Patric Teodorescu, Yuya Nagai, Guo Zhong, Vikram Mathews, Nina Isoherranen, Gabriel Ghiaur

Blood (2021) 138 (Supplement 1): 1166.

https://doi.org/10.1182/blood-2021-153244

Published: 2021

Journal Articles

CD38 deletion of human primary NK cells eliminates daratumumab-induced fratricide and boosts their effector activity

Meisam Naeimi Kararoudi, Yuya Nagai, Ezgi Elmas, Marcelo de Souza Fernandes Pereira, Syed Abbas Ali, Philip Hollingsworth Imus, Darren Wethington, Ivan Marques Borrello, Dean Anthony Lee, Gabriel Ghiaur

Blood (2020) 136 (21): 2416–2427.

https://doi.org/10.1182/blood.2020006200

Published: 2020

Includes: Supplemental data

NARROW

PSAT1 Suppression Drives a Targetable Serine Dependence in AML

Patient-Derived Models of Clonal Hematopoiesis Point to Cell-Intrinsic and -Extrinsic Contributions to Clonal Dominance and Lineage Imbalances

Clonal Dissection of MDS and Secondary AML Resolves Shared Splicing Neoantigens and Mechanistic Underpinnings of Hypomethylating Agent Therapeutic Response

Decitabine Synergizes with Replication Checkpoint Inhibitors in TP53 -Mutated Acute Myeloid Leukemia

Efficacy and Tolerability of Blinatumomab in Clinical Trial Ineligible Patients with CD19+ Leukemias

Acute Lymphoblastic Leukemia (ALL) Outcomes after Allogeneic Blood or Marrow Transplantation (alloBMT) with High-Dose Post-Transplantation Cyclophosphamide (PTCy) in the Era of More Effective Pre-Transplant Therapy

CRISPR-based rapid molecular diagnostic tests for fusion-driven leukemias

CYP26 Activity Maintains the Bone Marrow Niche and Stem Cell Homeostasis

Outcomes of Patients with TP53 -Mutated Myeloid Neoplasms (TP53-MN) and the Role of Allogenic Blood or Marrow Transplantation (alloBMT)

CCRL2 Promotes Cytokine-Regulated Growth of Erythroleukemia Cells

Allogeneic Blood or Marrow Transplantation (AlloBMT) with High-Dose Post-Transplantation Cyclophosphamide (PTCy) for Acute Lymphoblastic Leukemia (ALL) in Patients Aged ≥ 55: Best Results in B ALL in First Remission (CR1) with Reduced-Intensity Conditioning (RIC)

Single-Cell Multiomics Reveal Hypomethylating Agent Partially Restores Hematopoiesis in a LR-MDS Patient at the Cost of Leukemic Transformation

Gemtuzumab Ozogamicin for Cytoreduction in Hyperleukocytosis

PIM Inhibition By SEL24/MEN1703 Combines Synergistically with Gilteritinib in FLT3-ITD Preclinical Models of Acute Myeloid Leukemia

CD38 Is a Key Regulator of Tumor Growth By Modulating the Metabolic Signature of Malignant Plasma Cells

Single-Cell Transcriptomic and Proteomic Analysis of Acute Myeloid Leukemia (AML) Patients with Abnormalities on Chromosome 7

Response Prediction to Isocitrate Dehydrogenase (IDH) Inhibitors in Patients with IDH1 - or IDH2 -Mutated Acute Myeloid Leukemia Using Clinical and Genomic Data

Nonmyeloablative Allogeneic Transplantation in First Remission for Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia with Post-Transplantation Cyclophosphamide: Outcomes By Receipt of Pre-Transplant Blinatumomab

Arsenic Trioxide Reprograms the Bone-Marrow Microenvironment to Sensitize Minimal Residual Disease in Acute Myeloid Leukemia

CD38 deletion of human primary NK cells eliminates daratumumab-induced fratricide and boosts their effector activity

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American Society of Hematology

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American Society of Hematology

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