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Journal Articles

Novel T-Cell Receptor Signature Linked to Plasma Cell Dyscrasias

Yong Zhang, David G. Coffey, Elizabeth Hill, Frank Cross, Jr., Reena Philip, Marc R. Theoret, Ola Landgren, Andrea C Baines, Dickran Kazandjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1907.
https://doi.org/10.1182/blood-2024-202574
Published: 2024
Journal Articles

Efficacy and Safety of a NOVEL ANTI-CD20 Agent (SCT400) in CD20-Positive B-NHL: A Retrospective, Realworld Study in Chongqing, China

Li Jun, Yi Liu, Yong Zhang, Zhanshu Liu, Zailiang Yang, Guofa Xu, Xiaomei Zhang, Yifeng Tang, Chaoyu Wang, Qing Xiao, Xiaoqing Xie, Zailin Yang, Yingyu Nan, Jieping Li, Yao Liu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6516.
https://doi.org/10.1182/blood-2024-192934
Published: 2024
Journal Articles

Divergent Functions of ERK2 Substrate Binding Modalities in Myeloproliferative Neoplasm

Billy Truong, Monika Toma, Yong Zhang, Susan Shinton, Muheng Li, Xiang Hua, Dietmar Kappes, Paul Shapiro, Tomasz Skorski, David L. Wiest
Journal: Blood
Blood (2023) 142 (Supplement 1): 996.
https://doi.org/10.1182/blood-2023-191180
Published: 2023
Journal Articles

Neutralizing Antibody Responses in Patients with Hematological Malignancies after Omicron Infection: A Multicenter, Prospective Cohort Study in China

Li Jun, Yi Liu, Xia Wei, Zhanshu Liu, Zailiang Yang, Ling Liu, Meiyu Zhou, Guofa Xu, Lanting Chen, Yao Ding, Haike Lei, Zailin Yang, Shuang Chen, Xiaomei Zhang, Yifeng Tang, Yan Xiong, Jueyin Liu, Dehong Huang, Chunyan Xiao, Jun Liu, Tao Yang, Ying Xiang, Qiying Li, Yingyu Nan, Jieping Li, Yong Zhang, Yongzhong Wu, Yao Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2557.
https://doi.org/10.1182/blood-2023-179113
Published: 2023
Journal Articles

Risk Factors for Omicron Pneumonia in Patients with Hematological Malignancies: A Multicenter Study in China

Li Jun, Yi Liu, Xia Wei, Zhanshu Liu, Zailiang Yang, Ling Liu, Meiyu Zhou, Guofa Xu, Lanting Chen, Yao Ding, Haike Lei, Qiying Li, Yingyu Nan, Jieping Li, Yong Zhang, Yongzhong Wu, Yao Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3929.
https://doi.org/10.1182/blood-2023-179632
Published: 2023
Journal Articles

ERK2 Substrate Binding Domains Play Distinct Roles in Megakaryocytic-Erythroid Lineage Progression and Mediates Clonal Fitness in Myeloproliferative Neoplasms

Billy Truong, Yong Zhang, Esteban Martinez, Brianna Trankle, Anna-Mariya Kukuyan, Susan Shinton, James Oesterling, Xiang Hua, Dietmar J Kappes, Joan Font-Burgada, Tomasz Skorski, David Wiest
Journal: Blood
Blood (2022) 140 (Supplement 1): 6733–6734.
https://doi.org/10.1182/blood-2022-170264
Published: 2022
Journal Articles

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm

Yong Zhang, Billy Truong, Shawn P. Fahl, Esteban Martinez, Kathy Q. Cai, Essel D. Al-Saleem, Yulan Gong, Dan A. Liebermann, Jonathan Soboloff, Roland Dunbrack, Ross L. Levine, Steven Fletcher, Dietmar Kappes, Stephen M. Sykes, Paul Shapiro, David L. Wiest
Journal: Blood
Blood (2022) 140 (4): 359–373.
https://doi.org/10.1182/blood.2021013068
Published: 2022
Includes: Supplemental data
Journal Articles

Development of Anti-CD99scFvs for the Treatment of Acute Myeloid Leukemia

Yang Zhao, Jiawei Li, Vijaya Pooja Vaikari, Albert Lam, Atham Ali, Ophelia Meng, George Yaghmour, Yong Zhang, Houda Alachkar
Journal: Blood
Blood (2021) 138 (Supplement 1): 4345.
https://doi.org/10.1182/blood-2021-154304
Published: 2021
Journal Articles

Response Prediction to Isocitrate Dehydrogenase (IDH) Inhibitors in Patients with IDH1 - or IDH2 -Mutated Acute Myeloid Leukemia Using Clinical and Genomic Data

Emma C. Scott, Kamil Kural, Sean Smith, Michael Colgan, Alexander J. Ambinder, Gabriel Ghiaur, Nora Holmes, Dickran Kazandjian, Catherine Lai, Colleen McGuire, Lorraine Pelosof, Svetlana Petrovskaya, V. Ashutosh Rao, Amy Rosenberg, Luis Santana-Quintero, Joseph Wynne, Wenming Xiao, Yong Zhang, R. Angelo de Claro, Richard Pazdur, Julia A. Beaver, Kelly J. Norsworthy
Journal: Blood
Blood (2021) 138 (Supplement 1): 1285.
https://doi.org/10.1182/blood-2021-147099
Published: 2021
Journal Articles

A Novel Strategy for Off-the-Shelf T Cell Therapy Which Evades Allogeneic T Cell and NK Cell Rejection

Yong Zhang, Surbhi Goel, Aaron Prodeus, Utsav Jetley, Yiyang Tan, John Averill, Utkarsha Ranade, Ishina Balwani, Ivy Dutta, Palak Sharma, Priya Venkatesan, Dai Liu, Matthew Roy, Daniel O′Connell, Simo M Arredouani, Marie Keenan, Reynald Lescarbeau, Birgit C Schultes
Journal: Blood
Blood (2021) 138 (Supplement 1): 1711.
https://doi.org/10.1182/blood-2021-152999
Published: 2021
Journal Articles

ERK2 Substrate Binding Domains Perform Opposing Roles in Pathogenesis of a JAK2V617F-Driven Myeloproliferative Neoplasm

Billy Truong, Yong Zhang, Shawn Fahl, Kathy Q Cai, Esteban Martinez, Essel D. Al-Saleem, Yulan Gong, Dan Liebermann, Jonathan Soboloff, Roland Dunbrack, Ross L. Levine, Dietmar J Kappes, Stephen M. Sykes, Paul Shapiro, David Wiest
Journal: Blood
Blood (2021) 138 (Supplement 1): 2547.
https://doi.org/10.1182/blood-2021-152063
Published: 2021
Journal Articles

Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma

David G. Coffey, Francesco Maura, Edgar Gonzalez-Kozlova, Javier Diaz-Mejia3, Ping Luo, Yong Zhang, Yuexin Xu, Edus H. Warren, Eric L Smith, Hearn Jay Cho, Alexander Lesokhin, Benjamin Diamond, Dickran Kazandjian, Trevor J. Pugh, Damian J. Green, Sacha Gnjatic, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 329.
https://doi.org/10.1182/blood-2021-154506
Published: 2021
Journal Articles

Smarca5-mediated epigenetic programming facilitates fetal HSPC development in vertebrates

Yanyan Ding, Wen Wang, Dongyuan Ma, Guixian Liang, Zhixin Kang, Yuanyuan Xue, Yifan Zhang, Lu Wang, Jian Heng, Yong Zhang, Feng Liu
Journal: Blood
Blood (2021) 137 (2): 190–202.
https://doi.org/10.1182/blood.2020005219
Published: 2021
Includes: Supplemental data
Journal Articles

Treatment of High Risk (HR) Smoldering Multiple Myeloma (SMM) with Carfilzomib, Lenalidomide, and Dexamethasone (KRd) Followed By Lenalidomide Maintenance (-R): A Phase 2 Clinical and Correlative Study

Dickran Kazandjian, MD, Elizabeth Hill, MD, Candis Morrison, CNP, PhD, Alexander Dew, DO, MS, Neha Korde, MD, Sham Mailankody, MBBS, Elisabet E. Manasanch, MD, Mary L. Kwok, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Yong Zhang, PhD, Ashley Carpenter, RN, Monica Epstein, RN, Michael Emanuel, BSN, RN, Crystal Lu, PharmD, BCOP, Raul C. Braylan, MD, Katherine R. Calvo, MD PhD, Peter Choyke, MD, Alina Dulau-Florea, MD, Esther Mena, MD, Liza Lindenberg, MD, Irina Maric, MD MSci, Nisha Patel, DO, Maryalice Stetler-Stevenson, MD PhD, Hao-Wei Wang, MD PhD, Constance M. Yuan, MD PhD, Seth M. Steinberg, PhD, William D. Figg, PhD, Mark Roschewski, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–45.
https://doi.org/10.1182/blood-2020-136148
Published: 2020
Journal Articles

Developing a Genomics Model to Predict Failure of Isocitrate Dehydrogenase (IDH) Inhibitors for Treatment of Patients with IDH1- or IDH2-Mutated Acute Myeloid Leukemia

Tigran Ghazanchyan, MS, Dickran Kazandjian, MD, Donna Przepiorka, MD PhD, Kelly J. Norsworthy, MD, Emma Scott, PhD, Luis Santana-Quintero, PhD, Svetlana Petrovskaya, PhD, Yong Zhang, PhD, Amy Rosenberg, MD, Ashutosh Rao, PhD, Richard Pazdur, MD, Ann T. Farrell, MD, Julia A. Beaver, MD, Vahan Simonyan, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2815.
https://doi.org/10.1182/blood-2018-99-116870
Published: 2018
Journal Articles

A Phase 2 Study of Carfilzomib, Lenalidomide, and Dexamethasone with Lenalidomide Maintenance (KRd-r) in Newly Diagnosed Multiple Myeloma (NDMM): Sustained Long Term Deep Remissions and Prolonged Progression-Free Duration Regardless of Age or Cytogenetic Risk after 5 Years of Follow up

Dickran Kazandjian, MD, Neha Korde, MD, Sham Mailankody, MBBS, Yong Zhang, PhD, Jennifer Hsu, RN, Elizabeth Hill, MD, Candis Morrison, CNP, PhD, Sneha Divakarla, MHA, Mary L. Kwok, MD, Elisabet E. Manasanch, MD, Manisha Bhutani, MD, Nishant Tageja, MD, Pallavi Galera, Alina Dulau-Florea, MD, Dalia Salem, MD, Esther Gonzalez, MD, Liza Lindenberg, MD, Irina Maric, MD MSci, Katherine R. Calvo, MD PhD, Raul C. Braylan, MD, Constance Yuan, MD PhD, Wyndham H. Wilson, MD PhD, Peter Choyke, MD, Maryalice Stetler-Stevenson, MD PhD, Seth M. Steinberg, PhD, William Figg, PharmD, Mark Roschewski, MD, Ola Landgren, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1957.
https://doi.org/10.1182/blood-2018-99-111712
Published: 2018
Journal Articles

Blockade of IL-2 and IL-15 Gamma Chain Receptor Signaling Decreases Leukemic Cell Viability in T-Cell Large Granular Lymphocyte Leukemia and Adult T-Cell Leukemia

Tracy Tiffany Wang, BS, Jun Yang, MD, Yong Zhang, PhD, Meili Zhang, PhD, Kevin C Conlon, MD, Yutaka Tagaya, B.M., PhD, Thomas L Olson, PhD, David J Feith, PhD, Nazli Azimi, Pharm.D., PhD, Thomas A. Waldmann, MD, Thomas P Loughran, Jr., MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3585.
https://doi.org/10.1182/blood.V130.Suppl_1.3585.3585
Published: 2017
Journal Articles

Sustained High Rates of Complete Response and Minimal Residual Disease Negativity after 8 Cycles of Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (DEX) Followed By 2 Years of Lenalidomide Maintenance (CRd-R) in Patients with High-Risk Smoldering Multiple Myeloma: Updated Results of Clinical and Correlative Phase 2 Study

Dickran Kazandjian, MD, Neha S Korde, MD, Mark Roschewski, MD, Sham Mailankody, MD, Candis Morrison, RN, PhD, Elisabet E. Manasanch, MD, Mary L Kwok, MD, Nishant Tageja, MD, Manisha Bhutani, MD, Adriana Zingone, PhD, Rene Costello, Yong Zhang, PhD, Marcia Mulquin, Liz Lamping, Ashley Carpenter, Brenda Roberson, Irina Maric, MD, Katherine R. Calvo, MD PhD, Raul C Braylan, MD, Constance M. Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Diane C. Arthur, MD, Liza Lindenberg, Karen A. Kurdziel, MD, Peter Choyke, Seth M. Steinberg, PhD, William Figg, Wyndham H. Wilson, MD PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3339.
https://doi.org/10.1182/blood.V128.22.3339.3339
Published: 2016
Journal Articles

Ribosomal Protein Rpl22 Regulates Development and Transformation Via Altering RNA Processing

Minshi Wang, PhD, Zheng Ser, Shuyun Rao, PhD, Shawn Fahl, Yong Zhang, Suraj Peri, PhD, Alex Kentsis, MD PhD, David L Wiest, PhD
Journal: Blood
Blood (2016) 128 (22): 3878.
https://doi.org/10.1182/blood.V128.22.3878.3878
Published: 2016
Journal Articles

Sustained Minimal Residual Disease Negativity in Newly Diagnosed Multiple Myeloma (NDMM) Patients Treated with Carfilzomib (CFZ), Lenalidomide (LEN), and Dexamethasone (DEX) Followed By 2 Years of Lenalidomide Maintenance (CRd-R): Updated Results of a Phase 2 Study

Dickran Kazandjian, MD, Neha S Korde, MD, Mark Roschewski, MD, Sham Mailankody, MD, Candis Morrison, RN, PhD, Elisabet E. Manasanch, MD, Mary L Kwok, MD, Nishant Tageja, MD, Manisha Bhutani, MD, Adriana Zingone, PhD, Rene Costello, Yong Zhang, PhD, Marcia Mulquin, Liz Lamping, Ashley Carpenter, Brenda Roberson, Irina Maric, MD, Katherine R. Calvo, MD PhD, Raul C Braylan, MD, Constance M. Yuan, MD PhD, Maryalice Stetler-Stevenson, MD PhD, Diane C. Arthur, MD, Liza Lindenberg, Karen A. Kurdziel, MD, Peter Choyke, Seth M. Steinberg, PhD, William Figg, Wyndham H. Wilson, MD PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4527.
https://doi.org/10.1182/blood.V128.22.4527.4527
Published: 2016