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Trevor J. Pugh
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Journal Articles

Detection of Recurrent Mutations, Immunoglobulin Rearrangements and Copy Number Changes in Cell-Free DNA and Bone Marrow on Patients with Waldenstrom's Macroglobulinemia over a Course of Treatment

Signy Chow, Arnavaz Danesh, Kim Roos, Suzanne Trudel, Trevor J. Pugh, Christine I Chen, Neil Berinstein
Journal: Blood
Blood (2024) 144 (Supplement 1): 6215.
https://doi.org/10.1182/blood-2024-201658
Published: 2024
Journal Articles

Cell-Free DNA Whole Genome Sequencing for Non-Invasive MRD Detection in Multiple Myeloma

Dor D. Abelman, Jenna Eagles, Aimee Wong, Saumil Shah, Stephanie Pedersen, Sarah Bridges, Cecilia Bonolo De Campos, Darrell White, Irwindeep Sandhu, Kevin Song, Zac McDonald, Abir Khaled, Liqiang Yang, Alli Murugesan, Anthony Reiman, Suzanne Trudel, Trevor J. Pugh
Journal: Blood
Blood (2024) 144 (Supplement 1): 3338.
https://doi.org/10.1182/blood-2024-208740
Published: 2024
Journal Articles

Cell-Free DNA from Blood or Bone Marrow as Alternatives to Bone Marrow Cells for Molecular Diagnostics and Monitoring of Multiple Myeloma

Dor D. Abelman, Jenna Eagles, Stephanie Pedersen, Arnavaz Danesh, Danielle Croucher, Jeff P. Bruce, Stephenie D. Prokopec, Ellen N. Wei, Saumil Shah, Alli Murugesan, Anthony Reiman, Suzanne Trudel, Trevor J. Pugh
Journal: Blood
Blood (2023) 142 (Supplement 1): 4693.
https://doi.org/10.1182/blood-2023-173685
Published: 2023
Journal Articles

Normalization of the Immune Microenvironment during Lenalidomide Maintenance Is Associated with Sustained MRD Negativity in Patients with Multiple Myeloma

David G. Coffey, Francesco Maura, Edgar Gonzalez-Kozlova, Javier Diaz-Mejia3, Ping Luo, Yong Zhang, Yuexin Xu, Edus H. Warren, Eric L Smith, Hearn Jay Cho, Alexander Lesokhin, Benjamin Diamond, Dickran Kazandjian, Trevor J. Pugh, Damian J. Green, Sacha Gnjatic, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 329.
https://doi.org/10.1182/blood-2021-154506
Published: 2021
Journal Articles

Selective Cell State in the Clonally Expanded T-Cell Compartment of Vκ*MYC Mice Responding to Treatment with Checkpoint Inhibitors

Danielle C Croucher, Laura M Richards, Zhihua Li, Ellen nong Wei, Xian Fang Huang, Daniel Waller, Marta Chesi, P. Leif Bergsagel, Michael Sebag, Trevor J. Pugh, Suzanne Trudel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1581.
https://doi.org/10.1182/blood-2021-151242
Published: 2021
Journal Articles

Reduced Antigen Presentation May Contribute to Immunomodulatory Drug Resistance in Multiple Myeloma

David G. Coffey, MD, Ola Landgren, MD PhD, Yuexin Xu, PhD, Dickran Kazandjian, MD, Trevor J. Pugh, PhD, Sacha Gnjatic, PhD, Edus H. Warren, MD PhD, Damian J. Green, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4367.
https://doi.org/10.1182/blood-2019-126222
Published: 2019
Journal Articles

A Single-Cell Transcriptional Analysis of Tumour Cells and the Immune Microenvironment during Disease Evolution in a Transgenic Mouse Model of Myeloma

Danielle C Croucher, MSc, Marta Chesi, PhD, Zhihua Li, Victoria Marie Garbitt, BS, Meaghen E Sharik, BS, Daniel Waller, PhD, Michael Sebag, MD PhD, P. Leif Bergsagel, MD, Trevor J. Pugh, PhD, Suzanne Trudel, MD FRCP(C)
Journal: Blood
Blood (2018) 132 (Supplement 1): 56.
https://doi.org/10.1182/blood-2018-99-118691
Published: 2018
Journal Articles

Progression to AML Is Predictable and Distinct from Age Related Clonal Hematopoiesis

Sagi Abelson, PhD, Stanley W.K. Ng, Omer Wiessbrod, Philip Zuzarte, Lawrence Heisler, Yogi Sundaravadanam, Ting Ting Wang, Trevor J. Pugh, PhD, David Soave, Paul Brennan, Mattias Johansson, Phillip Awadalla, Scott V. Bratman, Jean Wang, MD PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Liran I. Shlush
Journal: Blood
Blood (2017) 130 (Supplement 1): 471.
https://doi.org/10.1182/blood.V130.Suppl_1.471.471
Published: 2017
Journal Articles

Targeted-Capture Sequencing Approach to V(D)J Rearrangement, Immunoglobulin (Ig) Translocation and Mutation Detection in Multiple Myeloma (MM): Potential Applications in Minimal Residual Disease (MRD) Analysis and Comparison to Multiparameter Flow Cytometry (MFC) in the Myeloma Canada Research Network (MCRN) 001 Study with Intravenous Busulfan and Melphalan (BuMel) Conditioning Followed By Lenalidomide Maintenance in Newly Diagnosed Multiple Myeloma (NDMM)

Signy Chow, MD FRCP(C), Donna Reece, MD FRCP(C), Jonathan J. Keats, PhD, P. Leif Bergsagel, MD, Nizar J. Bahlis, MD, Paola Neri, MD, Giovanni Piza Rodriguez, MD, Michael Sebag, MD PhD, Darrell J White, MD, Kevin Song, MD FRCP(C), Terrance Comeau, MD, Christopher P. Venner, MD, Christine I Chen, MD FRCP(C), Jean Roy, MD, Martha L Louzada, MD, Julie Stakiw, MD FRCP(C), Andrea Kew, MDFRCP(C), Vishal Kukreti, MD FRCP(C), Anca Prica, MD FRCP(C), Rodger Tiedemann, MBChB, PhD, Mariela Aura Pantoja, PhD MSc, Harminder Kaur Paul, MSc, Trevor J. Pugh, PhD, Suzanne Trudel, MD FRCP(C)
Journal: Blood
Blood (2017) 130 (Supplement 1): 3057.
https://doi.org/10.1182/blood.V130.Suppl_1.3057.3057
Published: 2017
Journal Articles

Biomarker Driven Phase II Clinical Trial of Trametinib in Relapsed/Refractory Multiple Myeloma with Sequential Addition of the AKT Inhibitor, GSK2141795 at Time of Disease Progression to Overcome Treatment Failure: A Trial of the Princess Margaret Phase II Consortium

Suzanne Trudel, MD, Nizar J. Bahlis, MD, Christopher P. Venner, MD, Annette E Hay, MB ChB, Olena Kis, PhD, Signy Chow, MD FRCPC, Zhi Hua Li, MD, Ellen Nong Wei, MSc, Lisa Wang, PhD, Christine Tran, Smitha Udagani, Chantale Blattler, Trevor J. Pugh, PhD, Helen X Chen, MD, Amit Oza, MD
Journal: Blood
Blood (2016) 128 (22): 4526.
https://doi.org/10.1182/blood.V128.22.4526.4526
Published: 2016
Journal Articles

Prospective Next-Generation Sequencing Molecular Profiling of Myeloid Malignancies: Assessment of Information Benefit and Impact on Patient Care

Suzanne Kamel-Reid, PhD DABMG, FACMG, Mariam Thomas, PhD, Mahadeo A. Sukhai, BSc, MSc, PhD, Dwayne L. Barber, PhD, Swati Garg, PhD, Maksym Misyura, PhD, Roozbeh Dolatshahi, Djamel Harbi, Tong Zhang, Anna Porwit, MDPhD, Jan M.A. Delabie, MD PhD, Narmin Ibrahimova, Mohamed Shanavas, MD FRACP, FRCPA, Karen W.L. Yee, MD, Trevor J. Pugh, PhD, Philippe Bedard, MD, Aaron D. Schimmer, MD PhD, Tracy L. Stockley, PhD, Vikas Gupta, MD FRCP, FRCPath, Mark D. Minden, MD PhD, Andre C Schuh, MD FRCPC
Journal: Blood
Blood (2015) 126 (23): 3848.
https://doi.org/10.1182/blood.V126.23.3848.3848
Published: 2015