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Journal Articles

Oncogenic Nexus of TET2 with Thpok in Myeloid Neoplasia

Ejike Ujoatu, Sohini Mukhopadhyay, Carmelo Gurnari, Valeria Visconte, Jaroslaw Maciejewski, Jayati Basu, Babal K. Jha, H. Leighton Grimes, Stephen Sykes, Dietmar Kappes

Blood (2024) 144 (Supplement 1): 2716.

https://doi.org/10.1182/blood-2024-207759

Published: 2024

Journal Articles

Clonal Dissection of MDS and Secondary AML Resolves Shared Splicing Neoantigens and Mechanistic Underpinnings of Hypomethylating Agent Therapeutic Response

Xuan Zhang, Guangyuan Li, Anna Oliverio, Jennifer VanOudenhove, Amy E. DeZern, Gabriel Ghiaur, Stephanie Halene, H. Leighton Grimes, Nathan Salomonis

Blood (2024) 144 (Supplement 1): 1810.

https://doi.org/10.1182/blood-2024-211099

Published: 2024

Journal Articles

Transcriptomically Defined Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) Phenotype Governs Mutation-Based Disease Group Assignment

Lorenz Oelschläger, Deedra Nicolet, Krzysztof Mrózek, Daniel Schnell, Najla Alotaibi, Christopher J. Walker, Alice Mims, James S. Blachly, Bayard L Powell, Jonathan E Kolitz, Eunice S. Wang, Andrew J. Carroll, Lynn van Rosmalen, Bettina Nadorp, Nathan Salomonis, H. Leighton Grimes, Maarten Fornerod, Ann-Kathrin Eisfeld

Blood (2024) 144 (Supplement 1): 641.

https://doi.org/10.1182/blood-2024-210423

Published: 2024

Journal Articles

Phip Is a Potent Leukemia Oncogene Identified in Acute Myeloid Leukemia (AML) Patients of African Ancestry

Bailee N. Kain, Sidharth Sen, Deedra Nicolet, Sierra N. Bennett, David Bernardicius, Yueh-Chiang Hu, Christopher Walker, Ann-Kathrin Eisfeld, Nathan Salomonis, H. Leighton Grimes

Blood (2024) 144 (Supplement 1): 327.

https://doi.org/10.1182/blood-2024-210463

Published: 2024

Journal Articles

Luspatercept Promotes Heme Biosynthesis and Erythroblast Island Formation in a Novel Low-Risk MDS Mouse Model

Maiko Sezaki, Asumi Yokota, Xuan Zhang, Mingzhe Pan, Zhihong Wang, Michihiro Hashimoto, Zohra Nooruddin, Eric M. Pietras, Nathan Salomonis, H. Leighton Grimes, Gang Huang

Blood (2024) 144 (Supplement 1): 877.

https://doi.org/10.1182/blood-2024-203695

Published: 2024

Journal Articles

MISTRG6kit W41 : Enhanced Engraftment in a Cytokine Humanized Patient-Derived Xenotransplantation Mouse Model

Amro Baassiri, Jamie Maziarz, Holly Nicole Blackburn, Hannah Maul-Newby, Jennifer VanOudenhove, Xuan Zhang, Martin Matthews, Sambuddha Paul, Wei Liu, Esen Sefik, Nathan Salomonis, H. Leighton Grimes, Richard Flavell, Stephanie Halene

Blood (2024) 144 (Supplement 1): 1815.

https://doi.org/10.1182/blood-2024-211908

Published: 2024

Journal Articles

Genomic Profiles and Associated Survival Prognosticators in Black Patients with Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 837.

https://doi.org/10.1182/blood-2023-181876

Published: 2023

Journal Articles

The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It

Sean Walulik, Sarai Dean, Eric J Vick, Xiaoqin Zhu, Mark Wunderlich, Chih-Hsing Chou, Kwangmin Choi, H. Leighton Grimes, Daniel T. Starczynowski, Linde A. Miles, Andrew Volk

Blood (2023) 142 (Supplement 1): 1410.

https://doi.org/10.1182/blood-2023-186180

Published: 2023

Journal Articles

Downregulation of Mitochondrial Complex II (MC II) in Myelodysplastic Syndromes

Maiko Sezaki, Michihiro Hashimoto, Asumi Yokota, Nathan Salomonis, H. Leighton Grimes, Gang Huang

Blood (2023) 142 (Supplement 1): 4583.

https://doi.org/10.1182/blood-2023-186829

Published: 2023

Journal Articles

Identification and Isolation of Hematopoietic Stem Cells and Progenitors with Discrete Developmental Gene Expression Programs

Kyle Ferchen, Baobao (Annie) Song, Chih-Hsing Chou, Xuan Zhang, Nathan Salomonis, H. Leighton Grimes

Blood (2022) 140 (Supplement 1): 2856.

https://doi.org/10.1182/blood-2022-169525

Published: 2022

Journal Articles

Sex-Associated Differences in Frequencies and Outcome Prognostication of Recurrent Molecular Features in Adults with Acute Myeloid Leukemia (AML) (AMLCG, CALGB [Alliance])

Blood (2022) 140 (Supplement 1): 936–939.

https://doi.org/10.1182/blood-2022-165395

Published: 2022

Journal Articles

Hematopoietic Flt3+ Multipotent Progenitors Are Organized in Discrete Functionally and Hierarchically Distinct Populations

Michael Solomon, Baobao (Annie) Song, Vinothini Govindarajah, Samantha Good, James Bartram, Jose Cancelas, Marie-Dominique Filippi, Nathan Salomonis, H. Leighton Grimes, Damien Reynaud

Blood (2022) 140 (Supplement 1): 1981–1982.

https://doi.org/10.1182/blood-2022-159781

Published: 2022

Journal Articles

Metallothionein 1 (MT1) Is Selectively Required for DNMT3A;NPM1 -Mutant Acute Myeloid Leukemia Proliferation

Patricia A. Colom Diaz, Chih-Hsing Chou, Jayna J Mistry, Nathan Salomonis, Mohammad Daud Khan, H. Leighton Grimes, Jennifer J Trowbridge

Blood (2022) 140 (Supplement 1): 9103–9104.

https://doi.org/10.1182/blood-2022-163355

Published: 2022

Journal Articles

Single-Cell Multiomics Reveal Hypomethylating Agent Partially Restores Hematopoiesis in a LR-MDS Patient at the Cost of Leukemic Transformation

Xuan Zhang, Baobao (Annie) Song, Mohammad Daud Khan, Kyle Ferchen, Chih-Hsing Chou, Guangyuan Li, Amy E. DeZern, Gabriel Ghiaur, Stephanie Halene, Nathan Salomonis, H. Leighton Grimes

Blood (2022) 140 (Supplement 1): 9759–9760.

https://doi.org/10.1182/blood-2022-169300

Published: 2022

Journal Articles

Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis

Laurel Romano, Katie G. Seu, Julien Papoin, David E. Muench, Diamantis Konstantinidis, André Olsson, Katrina Schlum, Kashish Chetal, Joel Anne Chasis, Narla Mohandas, Betsy J. Barnes, Yi Zheng, H. Leighton Grimes, Nathan Salomonis, Lionel Blanc, Theodosia A. Kalfa

Blood (2022) 140 (14): 1621–1634.

https://doi.org/10.1182/blood.2022015724

Published: 2022

Includes: Supplemental data

Journal Articles

Divisional Memory Drives Hematopoietic Stem Cell Functional Diversity

James Bartram, Baobao (Annie) Song, Juying Xu, Nathan Salomonis, H. Leighton Grimes, Marie-Dominique Filippi

Blood (2021) 138 (Supplement 1): 20.

https://doi.org/10.1182/blood-2021-153296

Published: 2021

Journal Articles

Neutrophil Development and Neutropenia

H. Leighton Grimes, PhD

Blood (2020) 136 (Supplement 1): SCI4.

https://doi.org/10.1182/blood-2020-133029

Published: 2020

Journal Articles

In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-143123

Published: 2020

Journal Articles

HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms

Blood (2020) 135 (3): 191–207.

https://doi.org/10.1182/blood.2019895326

Published: 2020

Includes: Supplemental data

Journal Articles

Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms

Blood (2019) 134 (Supplement_1): 474.

https://doi.org/10.1182/blood-2019-127235

Published: 2019

NARROW

Oncogenic Nexus of TET2 with Thpok in Myeloid Neoplasia

Clonal Dissection of MDS and Secondary AML Resolves Shared Splicing Neoantigens and Mechanistic Underpinnings of Hypomethylating Agent Therapeutic Response

Transcriptomically Defined Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) Phenotype Governs Mutation-Based Disease Group Assignment

Phip Is a Potent Leukemia Oncogene Identified in Acute Myeloid Leukemia (AML) Patients of African Ancestry

Luspatercept Promotes Heme Biosynthesis and Erythroblast Island Formation in a Novel Low-Risk MDS Mouse Model

MISTRG6kit W41 : Enhanced Engraftment in a Cytokine Humanized Patient-Derived Xenotransplantation Mouse Model

Genomic Profiles and Associated Survival Prognosticators in Black Patients with Acute Myeloid Leukemia

The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It

Downregulation of Mitochondrial Complex II (MC II) in Myelodysplastic Syndromes

Identification and Isolation of Hematopoietic Stem Cells and Progenitors with Discrete Developmental Gene Expression Programs

Sex-Associated Differences in Frequencies and Outcome Prognostication of Recurrent Molecular Features in Adults with Acute Myeloid Leukemia (AML) (AMLCG, CALGB [Alliance])

Hematopoietic Flt3+ Multipotent Progenitors Are Organized in Discrete Functionally and Hierarchically Distinct Populations

Metallothionein 1 (MT1) Is Selectively Required for DNMT3A;NPM1 -Mutant Acute Myeloid Leukemia Proliferation

Single-Cell Multiomics Reveal Hypomethylating Agent Partially Restores Hematopoiesis in a LR-MDS Patient at the Cost of Leukemic Transformation

Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis

Divisional Memory Drives Hematopoietic Stem Cell Functional Diversity

Neutrophil Development and Neutropenia

In Situ Fate Mapping of Native and Stress Myelopoiesis Reveals a Unique Niche for Mono- and Dendritic Cell -Poiesis

HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms

Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms

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American Society of Hematology

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ASH Publications

American Society of Hematology

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