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Journal Articles

Pyrimidine Starvation Is a Targetable Cancer Vulnerability: Mechanisms of Nucleotide Homeostasis

Jelena Milosevic, Johannes Elferich, Kashish Chetal, Mary Ayres, Varsha Gandhi, Ruslan Sadreyev, Nikolaus Grigorieff, Shobha Vasudevan, David Sykes
Journal: Blood
Blood (2023) 142 (Supplement 1): 4113.
https://doi.org/10.1182/blood-2023-186615
Published: 2023
Journal Articles

Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis

Laurel Romano, Katie G. Seu, Julien Papoin, David E. Muench, Diamantis Konstantinidis, André Olsson, Katrina Schlum, Kashish Chetal, Joel Anne Chasis, Narla Mohandas, Betsy J. Barnes, Yi Zheng, H. Leighton Grimes, Nathan Salomonis, Lionel Blanc, Theodosia A. Kalfa
Journal: Blood
Blood (2022) 140 (14): 1621–1634.
https://doi.org/10.1182/blood.2022015724
Published: 2022
Includes: Supplemental data
Journal Articles

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

David Muench, BS, Kyle Ferchen, BS, Chinavenmeni S. Velu, PhD, Kith Pradhan, PhD, Kashish Chetal, MS, Clemencia Colmenares, PhD, Amit Verma, MD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4350.
https://doi.org/10.1182/blood-2018-99-119441
Published: 2018
Journal Articles

Neutropenia-Associated Mutations Differentially Impact Developmental Cell-States

David Muench, BS, Kyle Ferchen, BS, Giang Pham, PhD, Somchai Chutipongtanate, MDPhD, Pankaj Dwivedi, PhD, Stuart Hay, Kashish Chetal, MS, Jayati Mookerjee-Basu, PhD, Kejian Zhang, MD MBA, Kasiani C. Myers, MD, Kristopher Nazor, PhD, Kenneth D Greis, PhD, Dietmar J Kappes, PhD, Sing Sing Way, MDPhD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 18.
https://doi.org/10.1182/blood-2018-99-116549
Published: 2018
Journal Articles

A Prognostic Human Splicing Signature That Precurses Leukemia

Meenakshi Venkatasubramanian, BS, Xiaoting Chen, PhD, Kashish Chetal, MS, Aishwarya Kulkarni, MS, Kasiani C. Myers, MD, Matthew T. Weirauch, PhD, H. Leighton Grimes, PhD, Nathan Salomonis, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 877.
https://doi.org/10.1182/blood-2018-99-115000
Published: 2018
Journal Articles

The Erythro-Myeloblastic Island (EMBI): A Hematopoietic Niche Balancing Erythropoiesis and Myelopoiesis

Katie Giger Seu, PhD, Laurel Romano, Julien Papoin, MS, Edward David Muench, Diamantis Konstantinidis, PhD BSc, André Olsson, MSc, PhD, Kashish Chetal, MS, Joel Anne Chasis, MD, Mohandas Narla, DSc, Nathan Salomonis, PhD, H Leighton Grimes, PhD, Lionel Blanc, PhD, Theodosia A. Kalfa, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 842.
https://doi.org/10.1182/blood-2018-99-118728
Published: 2018
Journal Articles

MLL-Fusion Leukemia Dependence on MBNL1 Is Associated with Alternative Splicing of Oncogenic Proteins

Arun Gurunathan, MD, Lana S Itskovich, PhD, Jason Clark, MS, Matthew Burwinkel, Nathan Salomonis, PhD, Meenakshi Venkatasubramanian, BS, Kashish Chetal, MS, Lynn Lee, MD, Ashish R Kumar, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3883.
https://doi.org/10.1182/blood-2018-99-112349
Published: 2018
Journal Articles

Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals Role of Cell Cycle in Fate Specification

Yi-Chien Lu, PhD, Diane S. Krause, MD PhD, Juliana Xavier-Ferrucio, PhD, Lin Wang, MS, Nathan Salomonis, PhD, Kashish Chetal, MS, Bruce J. Aronow, PhD, Chad Sanada, PhD, Meenakshi Venkatasubramanian, BS
Journal: Blood
Blood (2018) 132 (Supplement 1): 3828.
https://doi.org/10.1182/blood-2018-99-119105
Published: 2018
Journal Articles

SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness

e-blood
David E. Muench, Kyle Ferchen, Chinavenmeni S. Velu, Kith Pradhan, Kashish Chetal, Xiaoting Chen, Matthew T. Weirauch, Clemencia Colmenares, Amit Verma, Nathan Salomonis, H. Leighton Grimes
Journal: Blood
Blood (2018) 132 (21): e24–e34.
https://doi.org/10.1182/blood-2018-06-860890
Published: 2018
Includes: Supplemental data