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Journal Articles

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

David Muench, BS, Kyle Ferchen, BS, Chinavenmeni S. Velu, PhD, Kith Pradhan, PhD, Kashish Chetal, MS, Clemencia Colmenares, PhD, Amit Verma, MD, Nathan Salomonis, PhD, H. Leighton Grimes, PhD

Blood (2018) 132 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2018-99-119441

Published: 2018

Journal Articles

SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness

David E. Muench, Kyle Ferchen, Chinavenmeni S. Velu, Kith Pradhan, Kashish Chetal, Xiaoting Chen, Matthew T. Weirauch, Clemencia Colmenares, Amit Verma, Nathan Salomonis, H. Leighton Grimes

Blood (2018) 132 (21): e24–e34.

https://doi.org/10.1182/blood-2018-06-860890

Published: 2018

Includes: Supplemental data

Journal Articles

Transcriptional Control of HSC Fitness

David E. Muench, MEng, Chinavenmeni S. Velu, PhD, Andre Olsson, PhD, Sara E. Meyer, PhD, H. Leighton Grimes, PhD

Blood (2015) 126 (23): 1161.

https://doi.org/10.1182/blood.V126.23.1161.1161

Published: 2015

Journal Articles

Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease

Sonia D'Souza, Davide del Prete, Shunqian Jin, Quanhong Sun, Alissa J. Huston, Flavia Esteve Kostov, Benedicte Sammut, Chang-Sook Hong, Judith L. Anderson, Kenneth D. Patrene, Shibing Yu, Chinavenmeni S. Velu, Guozhi Xiao, H. Leighton Grimes, G. David Roodman, Deborah L. Galson

Blood (2011) 118 (26): 6871–6880.

https://doi.org/10.1182/blood-2011-04-346775

Published: 2011

Includes: Supplemental data

Journal Articles

Notch Signaling Requires Gfi1 for T Cell Development

James D. Phelan, B.S., Ingrid Saba, PhD, Chinavenmeni S. Velu, PhD, Tarik Moroy, Ph.D., H. Leighton Grimes, PhD

Blood (2011) 118 (21): 2174.

https://doi.org/10.1182/blood.V118.21.2174.2174

Published: 2011

Journal Articles

A Novel Combination of Chicken Hypersensitive Site-4 Insulator Elements Improves Titers and Restores Full Insulator Activity.

Paritha Arumugam, Fabrizia Urbinati, Phd., Chinavenmeni S. Velu, PhD, Tomoyasu Higashimoto, Phd., H. Leighton Grimes, PhD, Punam Malik

Blood (2009) 114 (22): 3566.

https://doi.org/10.1182/blood.V114.22.3566.3566

Published: 2009

Journal Articles

Epigenetic Signaling Is Required for HoxA9-Based Leukemic Transformation.

Aditya Chaubey, Ph.D., Chinavenmeni S. Velu, PhD, Shane Horman, PhD, Anil Jegga, Monica L. Guzman, PhD, Laurie Risner, Nancy J. Zeleznik-Le, PhD, Craig T. Jordan, PhD, Martin Carroll, MD, Brian Gebelein, Ph.D., H. Leighton Grimes, PhD

Blood (2009) 114 (22): 3966.

https://doi.org/10.1182/blood.V114.22.3966.3966

Published: 2009

Journal Articles

Rho GTPase Cdc42 is essential for B-lymphocyte development and activation

Fukun Guo, Chinavenmeni S. Velu, H. Leighton Grimes, Yi Zheng

Blood (2009) 114 (14): 2909–2916.

https://doi.org/10.1182/blood-2009-04-214676

Published: 2009

Journal Articles

Gfi1 integrates progenitor versus granulocytic transcriptional programming

Shane R. Horman, Chinavenmeni S. Velu, Aditya Chaubey, Tristan Bourdeau, Jinfang Zhu, William E. Paul, Brian Gebelein, H. Leighton Grimes

Blood (2009) 113 (22): 5466–5475.

https://doi.org/10.1182/blood-2008-09-179747

Published: 2009

Journal Articles

Gfi1 regulates miR-21 and miR-196b to control myelopoiesis

Chinavenmeni S. Velu, Avinash M. Baktula, H. Leighton Grimes

Blood (2009) 113 (19): 4720–4728.

https://doi.org/10.1182/blood-2008-11-190215

Published: 2009

Includes: Supplemental data

Journal Articles

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

Relja Popovic, Laurie E. Riesbeck, Chinavenmeni S. Velu, Aditya Chaubey, Jiwang Zhang, Nicholas J. Achille, Frank E. Erfurth, Katherine Eaton, Jun Lu, H. Leighton Grimes, Jianjun Chen, Janet D. Rowley, Nancy J. Zeleznik-Le

Blood (2009) 113 (14): 3314–3322.

https://doi.org/10.1182/blood-2008-04-154310

Published: 2009

Journal Articles

Gfi1 as a Regulator of Hematopoietic Differentiation.

H. Leighton Grimes, PhD, Chinavenmeni S. Velu, PhD, Shane Horman, PhD, Aditya Chaubey, PhD, Tristan Bourdeau, MS, Haiming Xu, Jinfang Zhu, PhD, William Paul, MD, Clemencia Colmenares, PhD, David A. Williams, MD, Brian Gebelein, PhD

Blood (2008) 112 (11): sci-16.

https://doi.org/10.1182/blood.V112.11.sci-16.sci-16

Published: 2008

Journal Articles

The 3′ End of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to the 5′ Insulator Core and Is Necessary in Conjunction with the Core for Full Insulator Activity

Paritha Arumugam, Fabrizia Urbinati, PhD., Chinavenmeni S. Velu, PhD, H. Leighton Grimes, PhD, Punam Malik, MD

Blood (2008) 112 (11): 817.

https://doi.org/10.1182/blood.V112.11.817.817

Published: 2008

Journal Articles

GFI1 Is a Tumor Suppressor in Myeloid Progenitors

Aditya Chaubey, Ph.D., Shane Hormon, Chinavenmeni S. Velu, PhD, Tristan Bourdeau, MS, BS, Jinfang Zhu, Ph.D., William Paul, M.D., Anil Jegga, Brian Gebelein, Ph.D., H. Leighton Grimes, PhD

Blood (2008) 112 (11): 2942.

https://doi.org/10.1182/blood.V112.11.2942.2942

Published: 2008

Journal Articles

Deregulation of MicroRNA Underlies Severe Congenital Neutropenia Pathogenesis

ChinavenMeni S. Velu, PhD, Avinash M Baktula, MS, Tristan Bourdeau, MS, H. Leighton Grimes, PhD

Blood (2008) 112 (11): 313.

https://doi.org/10.1182/blood.V112.11.313.313

Published: 2008

Journal Articles

The Ski oncoprotein regulates Hematopoietic Stem Cell Fitness and Functions as a Corepressor for Gfi1.

Chinavenmeni S. Velu, PhD, Michael Berk, Haiming Xu, Tristan Bourdeau, MS, Avedis Kazanjian, David A. Williams, MD, Clemencia Colmenares, Ph.D., H. Leighton Grimes, PhD

Blood (2008) 112 (11): 1403.

https://doi.org/10.1182/blood.V112.11.1403.1403

Published: 2008

Journal Articles

Ajuba Functions as An HDAC-Dependent Co-Repressor for Autoregulation of the Growth Factor Independent-1 Transcription Factor

Meghan E. B. Rojas, MS, Chinavenmeni S. Velu, PhD, Diego E. Montoya-Durango, PhD, Avedis Kazanjian, Chris M. Jay, PhD, Gregory D. Longmore, PhD, H. Leighton Grimes, PhD

Blood (2008) 112 (11): 3582.

https://doi.org/10.1182/blood.V112.11.3582.3582

Published: 2008

Journal Articles

The Human Severe Congenital Neutropenia-Associated Gfi1N382S Mutant Critically Requires Deregulated Expression of CSF1 To Block Granulopoiesis.

Chinavenmeni S. Velu, PhD, Avinash M. Baktula, Tristan Bourdeau, Shane R. Horman, PhD, H. Leighton Grimes, PhD

Blood (2007) 110 (11): 1248.

https://doi.org/10.1182/blood.V110.11.1248.1248

Published: 2007

Journal Articles

microRNA Control of Hematopoietic Stem Cell Fitness and Myelopoiesis.

Chinavenmeni S. Velu, PhD, Sarah Porteous, PhD, Haiming Xu, Avinash M. Baktula, Philip Roehrs, MD, Tristan Bourdeau, Ed Stavnezer, PhD, David Williams, MD, Clemencia Colmenares, PhD, H. Leighton Grimes, PhD

Blood (2007) 110 (11): 373.

https://doi.org/10.1182/blood.V110.11.373.373

Published: 2007

Journal Articles

miR-21 Is a Transcriptional Target of Growth Factor Independent -1; Implications for Transcriptional Regulation of microRNA.

Chinavenmeni S. Velu, PhD, Anil G. Jegga, Ph.D., Vivek Kaimal, Bruce Aronow, Ph.D., H. Leighton Grimes, Ph.D.

Blood (2006) 108 (11): 1178.

https://doi.org/10.1182/blood.V108.11.1178.1178

Published: 2006

NARROW

SKI Controls MDS-Associated Chronic TGFb Signaling, Aberrant Splicing, and Stem Cell Fitness

SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness

Transcriptional Control of HSC Fitness

Gfi1 expressed in bone marrow stromal cells is a novel osteoblast suppressor in patients with multiple myeloma bone disease

Notch Signaling Requires Gfi1 for T Cell Development

A Novel Combination of Chicken Hypersensitive Site-4 Insulator Elements Improves Titers and Restores Full Insulator Activity.

Epigenetic Signaling Is Required for HoxA9-Based Leukemic Transformation.

Rho GTPase Cdc42 is essential for B-lymphocyte development and activation

Gfi1 integrates progenitor versus granulocytic transcriptional programming

Gfi1 regulates miR-21 and miR-196b to control myelopoiesis

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization

Gfi1 as a Regulator of Hematopoietic Differentiation.

The 3′ End of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to the 5′ Insulator Core and Is Necessary in Conjunction with the Core for Full Insulator Activity

GFI1 Is a Tumor Suppressor in Myeloid Progenitors

Deregulation of MicroRNA Underlies Severe Congenital Neutropenia Pathogenesis

The Ski oncoprotein regulates Hematopoietic Stem Cell Fitness and Functions as a Corepressor for Gfi1.

Ajuba Functions as An HDAC-Dependent Co-Repressor for Autoregulation of the Growth Factor Independent-1 Transcription Factor

The Human Severe Congenital Neutropenia-Associated Gfi1N382S Mutant Critically Requires Deregulated Expression of CSF1 To Block Granulopoiesis.

microRNA Control of Hematopoietic Stem Cell Fitness and Myelopoiesis.

miR-21 Is a Transcriptional Target of Growth Factor Independent -1; Implications for Transcriptional Regulation of microRNA.

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American Society of Hematology

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American Society of Hematology

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