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Journal Articles

Foamy Virus Backbone Has Insulator Properties Which Remarkably Reduce Its Genotoxicity Potential

Michael Goodman, MD, Paritha Arumugam, PhD, Devin Pillis, MS, Danielle Lynn, MS, Johannes C.M. Van der Loo, PhD, Mehdi Keddache, PhD, Thomas R. Bauer, Jr., PhD, Dennis D. Hickstein, MD, David W Russell, MD PhD, Punam Malik, MD

Blood (2016) 128 (22): 1002.

https://doi.org/10.1182/blood.V128.22.1002.1002

Published: 2016

Journal Articles

Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness

Marthe-Sandrine Eiymo Mwa Mpollo, PhD, Eric Brandt, PhD, Shiva Kumar Shanmukhappa, DVM, PhD, Paritha Arumugam, PhD, Swati Tiwari, Anastacia Loberg, Tilat Rizvi, PhD, Mark Lindsey, Bart Jonckx, PhD, Peter Carmeliet, Prof MD PhD, Vijay Kalra, Timothy Lecras, PhD, Nancy Ratner, PhD, Marsha wills-Karp, PhD, Gurjit Khurana hershey, MD PhD, Punam Malik, MD

Blood (2015) 126 (23): 977.

https://doi.org/10.1182/blood.V126.23.977.977

Published: 2015

Journal Articles

Innovative Hematopoietic Gene-Therapy Concepts for Hereditary Pulmonary Alveolar Proteinosis Utilizing Hematopoietic Stem Cell Derived Macrophages

Nico Lachmann, PhD, Christine Happle, MD, Takuji Suzuki, MD, Miriam Hetzel, Kevin A. Link, PhD, Adele Mucci, Paritha Arumugam, PhD, Jens Bankstahl, PhD, Dagmar Dilloo, MD, Punam Malik, MD, Carolyn Lutzko, PhD, Axel Schambach, MD PhD, Bruce Colston Trapnell, MD, Gesine Hansen, MD, Thomas Moritz, MD

Blood (2015) 126 (23): 4417.

https://doi.org/10.1182/blood.V126.23.4417.4417

Published: 2015

Journal Articles

Safety Of a Gamma Globin Expressing Lentivirus Vector In a Non-Human Primate Model For Gene Therapy Of Sickle Cell Disease

Hans-Peter Kiem, MD, Paritha Arumugam, PhD, Burtner Christopher, PhD, Jennifer E Adair, PhD, Brian C Beard, PhD, Catherine Fox, MS, Punam Malik, MD

Blood (2013) 122 (21): 2896.

https://doi.org/10.1182/blood.V122.21.2896.2896

Published: 2013

Journal Articles

Diminished Multi-Organ Pathologies and Inflammation Associated With Sickle Cell Disease In Mice With Genetically Limited Prothrombin Levels

Paritha Arumugam, PhD, Eric S. Mullins, MD, Maureen A Shaw, MS, Kumar Shanmukhappa, BVSc., PhD, Anastacia Loberg, Tilat Rizvi, PhD, Janaka Wansapura, PhD, David Witte, MD, Punam Malik, MD, Jay L. Degen, PhD

Blood (2013) 122 (21): 729.

https://doi.org/10.1182/blood.V122.21.729.729

Published: 2013

Journal Articles

Gene Therapy for Hemophagocytic Lymphohistiocytosis (HLH): Fixing a Criticial ‘Circuit Breaker’ in the Immune System.

Michael Jordan, MD, Marlene Carmo, PhD, Swati Tiwari, Paritha Arumugam, PhD, Kimberly Risma, MD PhD, Bobby Gaspar, MD, Punam Malik, MD

Blood (2012) 120 (21): 3158.

https://doi.org/10.1182/blood.V120.21.3158.3158

Published: 2012

Journal Articles

Use of the in Vitro Immortalization Assay to Quantify the Impact of Integration Spectrum and Vector Design on Insertional Mutagenesis

Ute Modlich, DVM, PhD, Julia Sürth, Daniela Zychlinski, PhD, Johann Meyer, PhD, Christian Brendel, Manuel Grez, PhD, Paritha Arumugam, PhD, Punam Malik, MD, Elke Grassman, PhD, Axel Schambach, MD PhD, Christopher Baum, MD

Blood (2011) 118 (21): 3123.

https://doi.org/10.1182/blood.V118.21.3123.3123

Published: 2011

Journal Articles

A Novel Combination of Chicken Hypersensitive Site-4 Insulator Elements Improves Titers and Restores Full Insulator Activity.

Paritha Arumugam, Fabrizia Urbinati, Phd., Chinavenmeni S. Velu, PhD, Tomoyasu Higashimoto, Phd., H. Leighton Grimes, PhD, Punam Malik

Blood (2009) 114 (22): 3566.

https://doi.org/10.1182/blood.V114.22.3566.3566

Published: 2009

Journal Articles

The 3′ End of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to the 5′ Insulator Core and Is Necessary in Conjunction with the Core for Full Insulator Activity

Paritha Arumugam, Fabrizia Urbinati, PhD., Chinavenmeni S. Velu, PhD, H. Leighton Grimes, PhD, Punam Malik, MD

Blood (2008) 112 (11): 817.

https://doi.org/10.1182/blood.V112.11.817.817

Published: 2008

Journal Articles

Mechanism of Reduction in Titers from Lentivirus Vectors Carrying Chromatin Insulator Elements in the 3′ LTR

Fabrizia Urbinati, Paritha Arumugam, Tomoyasu Higashimoto, Anil Perumbeti, Ping Xia, Punam Malik

Blood (2008) 112 (11): 2359.

https://doi.org/10.1182/blood.V112.11.2359.2359

Published: 2008

Journal Articles

Mechanism of Reduction in Titers with Vectors Flanked by Chromatin Insulator Elements

Fabrizia Urbinati, PhD, Paritha Arumugam, Ph.D, Tomoyasu Higashimoto, Ph.D, Ping Xia, M.D, Punam Malik, M.D.

Blood (2007) 110 (11): 3734.

https://doi.org/10.1182/blood.V110.11.3734.3734

Published: 2007

NARROW

Foamy Virus Backbone Has Insulator Properties Which Remarkably Reduce Its Genotoxicity Potential

Placenta Growth Factor Links the IL-13 Response and the Leukotriene Pathway to Augment Airway Hyper-Responsiveness

Innovative Hematopoietic Gene-Therapy Concepts for Hereditary Pulmonary Alveolar Proteinosis Utilizing Hematopoietic Stem Cell Derived Macrophages

Safety Of a Gamma Globin Expressing Lentivirus Vector In a Non-Human Primate Model For Gene Therapy Of Sickle Cell Disease

Diminished Multi-Organ Pathologies and Inflammation Associated With Sickle Cell Disease In Mice With Genetically Limited Prothrombin Levels

Gene Therapy for Hemophagocytic Lymphohistiocytosis (HLH): Fixing a Criticial ‘Circuit Breaker’ in the Immune System.

Use of the in Vitro Immortalization Assay to Quantify the Impact of Integration Spectrum and Vector Design on Insertional Mutagenesis

A Novel Combination of Chicken Hypersensitive Site-4 Insulator Elements Improves Titers and Restores Full Insulator Activity.

The 3′ End of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to the 5′ Insulator Core and Is Necessary in Conjunction with the Core for Full Insulator Activity

Mechanism of Reduction in Titers from Lentivirus Vectors Carrying Chromatin Insulator Elements in the 3′ LTR

Mechanism of Reduction in Titers with Vectors Flanked by Chromatin Insulator Elements

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American Society of Hematology

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ASH Publications

American Society of Hematology

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