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Journal Articles

Aberrant Splicing in CHEK1 Is a Driver of Megakaryocytic Dysplasia in U2AF1 S34F Mutant Myelodysplastic Syndromes

Wenjun Zhang, Jinqin Liu, Gang Huang, Zhijian Xiao, Bing Li

Blood (2024) 144 (Supplement 1): 3193.

https://doi.org/10.1182/blood-2024-200825

Published: 2024

Journal Articles

Chromatin Modifier Hmga1 Maintains Hematopoietic Stem Cell Integrity in Stress Conditions

Jie Bai, Supannika Sorin, Arusyak Ivanyan, Mihoko Iimori, Ai Hamashima, Gang Huang, Kimi Araki, Goro Sashida

Blood (2024) 144 (Supplement 1): 26.

https://doi.org/10.1182/blood-2024-212002

Published: 2024

Journal Articles

Loss of Cpt1a Results in Elevated Mitochondrial Reactive Oxygen Species from Glucose-Fueled Mitochondrial Oxidative Phosphorylation and Defective Hematopoietic Stem Cells

Jue Li, Michihiro Hashimoto, Mingzhe Pan, Hui Zeng, Paul R. Andreassen, Gang Huang

Blood (2024) 144 (Supplement 1): 4035.

https://doi.org/10.1182/blood-2024-206240

Published: 2024

Journal Articles

Luspatercept Promotes Heme Biosynthesis and Erythroblast Island Formation in a Novel Low-Risk MDS Mouse Model

Maiko Sezaki, Asumi Yokota, Xuan Zhang, Mingzhe Pan, Zhihong Wang, Michihiro Hashimoto, Zohra Nooruddin, Eric M. Pietras, Nathan Salomonis, H. Leighton Grimes, Gang Huang

Blood (2024) 144 (Supplement 1): 877.

https://doi.org/10.1182/blood-2024-203695

Published: 2024

Journal Articles

CD38 Overexpressed Monocytes Play a Critical Role in the Fibrogenesis in Myeloproliferative Neoplasms and Can be Used As a Therapeutic Target to Ameliorate Fibrosis

Yiru Yan, Jinqin Liu, Lin Yang, Gang Huang, Xiaofan Zhu, Raajit Rampal, Zhijian Xiao, Bing Li

Blood (2024) 144 (Supplement 1): 874.

https://doi.org/10.1182/blood-2024-202529

Published: 2024

Journal Articles

Pharmacological Evaluation of a First-in-Class Hemoglobin Elevating Agent (HbEA) AND017 in Townes SCD Mouse Model

Gang Huang, Jie Bai, Mingzhe Pan, Dong Liu, Min Xiong, Shaojiang Deng

Blood (2024) 144 (Supplement 1): 2488.

https://doi.org/10.1182/blood-2024-208058

Published: 2024

Journal Articles

Pharmacological Evaluation of a First-in-Class Hemoglobin Elevating Agent (HbEA) AND017 in a Mouse MDS Model of an Inducible Mutant c-Myc Knock-in

Gang Huang, Jie Bai, Mingzhe Pan, Dong Liu, Min Xiong, Shaojiang Deng

Blood (2024) 144 (Supplement 1): 4140.

https://doi.org/10.1182/blood-2024-207858

Published: 2024

Journal Articles

U2AF1 S34F Mutation Promote Megakaryopoiesis and Fibrogenesis in MDS

Wenjun Zhang, Jinqin Liu, Lin Yang, Yiru Yan, Tiejun Qin, Zefeng Xu, Gang Huang, Bing Li, Zhijian Xiao

Blood (2023) 142 (Supplement 1): 5685.

https://doi.org/10.1182/blood-2023-185678

Published: 2023

Journal Articles

Downregulation of Mitochondrial Complex II (MC II) in Myelodysplastic Syndromes

Maiko Sezaki, Michihiro Hashimoto, Asumi Yokota, Nathan Salomonis, H. Leighton Grimes, Gang Huang

Blood (2023) 142 (Supplement 1): 4583.

https://doi.org/10.1182/blood-2023-186829

Published: 2023

Journal Articles

Conserved and Unique Regulatory Mechanisms of RUNX1 in Hematopoietic Stem/Progenitor Cell Subpopulations in Both Normal Hematopoiesis and FPD/AML Development

Chen Wang, Yi Zheng, Cuiqing Fan, Zhaowei Tu, Xiongwei Cai, Jianqiang Wu, Gang Huang

Blood (2023) 142 (Supplement 1): 1314.

https://doi.org/10.1182/blood-2023-190129

Published: 2023

Journal Articles

CPT1a Controls the Function of Long-Term Hematopoietic Stem Cells By Regulating the Balance between Fatty Acid Oxidation and Oxphos in Mitochondria

Michihiro Hashimoto, Jue Li, Paul R. Andreassen, Gang Huang

Blood (2023) 142 (Supplement 1): 4089.

https://doi.org/10.1182/blood-2023-187411

Published: 2023

Journal Articles

Food for thought (and CML survival)

Maiko Sezaki, Gang Huang

Blood (2023) 142 (6): 502–504.

https://doi.org/10.1182/blood.2023021051

Published: 2023

Journal Articles

Mutational Landscape, Clonal Evolution and Prognostic Effect of Non-Driver Mutations during Disease Progression of Primary Myelofibrosis

Xin Yan, Zefeng Xu, Shiqiang Qu, Tiejun Qin, Gang Huang, Zhijian Xiao, Bing Li

Blood (2022) 140 (Supplement 1): 3965–3967.

https://doi.org/10.1182/blood-2022-165185

Published: 2022

Journal Articles

The Transcriptional Factor ONECUT3 Is a Driver and Therapeutic Target for Complex Karyotype MDS

Yingwan Luo, Xiaomin Feng, Wei Lang, Chen Mei, Rongzhen Xu, Gang Huang, Hongyan Tong

Blood (2022) 140 (Supplement 1): 4018–4019.

https://doi.org/10.1182/blood-2022-166618

Published: 2022

Journal Articles

Ixazomib Based Maintenance Therapy for the Patients with Newly Diagnosed Multiple Myeloma in Real-World Practice

Blood (2021) 138 (Supplement 1): 2718.

https://doi.org/10.1182/blood-2021-149058

Published: 2021

Journal Articles

Clonal Architecture Analysis of TET2 Identified Distinct Origins in Myelodysplastic Syndromes

Zhongxun Shi, MD, Bing Li, MD, Tiejun Qin, MD, Zefeng Xu, MD, Lijuan Pan, MD, Shiqiang Qu, MD, Gang Huang, PhD, Zhijian Xiao, MD

Blood (2020) 136 (Supplement 1): 18.

https://doi.org/10.1182/blood-2020-139329

Published: 2020

Journal Articles

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Chen Wang, MD, Weinan Wang, BS, Lei Huang, PhD, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-140769

Published: 2020

Journal Articles

Myelodysplastic Syndromes-Associated Gene Mutations Lead to Pseudohypoxia Condition and Epigenome Hyper-Methylation in Mouse Genetic Models

Asumi Yokota, PhD, Lulu Zhang, PhD, Jianhua Feng, Xiaomin Feng, MD PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD

Blood (2019) 134 (Supplement_1): 1696.

https://doi.org/10.1182/blood-2019-126799

Published: 2019

Journal Articles

Impact of U2AF1 Mutations on Clinical Characteristics and RNA Splicing in Myelodysplastic Syndromes (MDS)

Bing Li, MD, Jinqin Liu, Tiejun Qin, Zefeng Xu, MD, Gang Huang, PhD, Zhijian Xiao, MD

Blood (2019) 134 (Supplement_1): 2979.

https://doi.org/10.1182/blood-2019-126346

Published: 2019

Journal Articles

Cell-Intrinsic Inflammation Drives Progression from Myelodysplastic Syndromes to Leukemia

Laura Barreyro, PhD, Avery Sampson, BSc, Kathleen Hueneman, Kwangmin Choi, PhD, Susanne Christie, BSc, Dehua Wang, MD, Gang Huang, PhD, Daniel T. Starczynowski, PhD

Blood (2019) 134 (Supplement_1): 2983.

https://doi.org/10.1182/blood-2019-127307

Published: 2019

NARROW

Aberrant Splicing in CHEK1 Is a Driver of Megakaryocytic Dysplasia in U2AF1 S34F Mutant Myelodysplastic Syndromes

Chromatin Modifier Hmga1 Maintains Hematopoietic Stem Cell Integrity in Stress Conditions

Loss of Cpt1a Results in Elevated Mitochondrial Reactive Oxygen Species from Glucose-Fueled Mitochondrial Oxidative Phosphorylation and Defective Hematopoietic Stem Cells

Luspatercept Promotes Heme Biosynthesis and Erythroblast Island Formation in a Novel Low-Risk MDS Mouse Model

CD38 Overexpressed Monocytes Play a Critical Role in the Fibrogenesis in Myeloproliferative Neoplasms and Can be Used As a Therapeutic Target to Ameliorate Fibrosis

Pharmacological Evaluation of a First-in-Class Hemoglobin Elevating Agent (HbEA) AND017 in Townes SCD Mouse Model

Pharmacological Evaluation of a First-in-Class Hemoglobin Elevating Agent (HbEA) AND017 in a Mouse MDS Model of an Inducible Mutant c-Myc Knock-in

U2AF1 S34F Mutation Promote Megakaryopoiesis and Fibrogenesis in MDS

Downregulation of Mitochondrial Complex II (MC II) in Myelodysplastic Syndromes

Conserved and Unique Regulatory Mechanisms of RUNX1 in Hematopoietic Stem/Progenitor Cell Subpopulations in Both Normal Hematopoiesis and FPD/AML Development

CPT1a Controls the Function of Long-Term Hematopoietic Stem Cells By Regulating the Balance between Fatty Acid Oxidation and Oxphos in Mitochondria

Food for thought (and CML survival)

Mutational Landscape, Clonal Evolution and Prognostic Effect of Non-Driver Mutations during Disease Progression of Primary Myelofibrosis

The Transcriptional Factor ONECUT3 Is a Driver and Therapeutic Target for Complex Karyotype MDS

Ixazomib Based Maintenance Therapy for the Patients with Newly Diagnosed Multiple Myeloma in Real-World Practice

Clonal Architecture Analysis of TET2 Identified Distinct Origins in Myelodysplastic Syndromes

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Myelodysplastic Syndromes-Associated Gene Mutations Lead to Pseudohypoxia Condition and Epigenome Hyper-Methylation in Mouse Genetic Models

Impact of U2AF1 Mutations on Clinical Characteristics and RNA Splicing in Myelodysplastic Syndromes (MDS)

Cell-Intrinsic Inflammation Drives Progression from Myelodysplastic Syndromes to Leukemia

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American Society of Hematology

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American Society of Hematology

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