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Journal Articles

Conserved and Unique Regulatory Mechanisms of RUNX1 in Hematopoietic Stem/Progenitor Cell Subpopulations in Both Normal Hematopoiesis and FPD/AML Development

Chen Wang, Yi Zheng, Cuiqing Fan, Zhaowei Tu, Xiongwei Cai, Jianqiang Wu, Gang Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1314.
https://doi.org/10.1182/blood-2023-190129
Published: 2023
Journal Articles

RUNX1 Mutation Leads to Megakaryocyte-Primed Hematopoietic Stem Cell Expansion and Familial Platelet Disorder

Chen Wang, MD, Weinan Wang, BS, Lei Huang, PhD, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-140769
Published: 2020
Journal Articles

Precision Assessment of on- and Off-Target Effects of mTOR Kinase Inhibitors in a Mouse Model

Cuiqing Fan, PhD, Xiongwei Cai, PhD, Feng Zhang, PhDcandidate, Cindy Hochstetler, PhDcandidate, Xiaoyi Chen, PhD, Fukun Guo, PhD, Weidong Tian, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2632.
https://doi.org/10.1182/blood-2018-99-115225
Published: 2018
Journal Articles

Inducible Correction of a RUNX1 Mutation of Human AML Causes a Switch of AML to B-ALL

Chen Wang, PhDcandidate, Yoshihiro Hayashi, MD PhD, Xiongwei Cai, PhD, Xiaomei Yan, MD PhD, Gang Huang, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1325.
https://doi.org/10.1182/blood-2018-99-116919
Published: 2018
Journal Articles

mTOR Restricts Chromatin Access and Genomic Activity to Maintain Hematopoietic Stem Cell Quiescence and Engraftment

Cuiqing Fan, PhD, Chuntao Zhao, PhD, Feng Zhang, Xiongwei Cai, PhD, Lingli Xu, Shan Lin, PhD, Xiaoyi Chen, PhD, Fukun Guo, PhD, Richard Q Lu, PhD, Weidong Tian, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2416.
https://doi.org/10.1182/blood.V130.Suppl_1.2416.2416
Published: 2017
Journal Articles

Loss of Function RUNX1 Mutations Restrict Protein Biosynthesis during Pre-Leukemia and MDS Transition but Not after Leukemic Transformation

Xiongwei Cai, PhD, Yoshihiro Hayashi, MD PhD, Mark Wunderlich, MS, Nancy A. Speck, PhD, James C. Mulloy, PhD, Gang Huang, PhD, Yi Zheng, PhD
Journal: Blood
Blood (2016) 128 (22): 3860.
https://doi.org/10.1182/blood.V128.22.3860.3860
Published: 2016
Journal Articles

Runx1 and Cbfβ regulate the development of Flt3 + dendritic cell progenitors and restrict myeloproliferative disorder

Ansuman T. Satpathy, Carlos G. Briseño, Xiongwei Cai, Drew G. Michael, Chun Chou, Sunnie Hsiung, Deepta Bhattacharya, Nancy A. Speck, Takeshi Egawa
Journal: Blood
Blood (2014) 123 (19): 2968–2977.
https://doi.org/10.1182/blood-2013-11-539643
Published: 2014
Includes: Supplemental data
Journal Articles

Inherited and Acquired RUNX1 Mutations in Hematologic Disorders

Nancy A. Speck, PhD, Xiongwei Cai, Ph.D., Jingping Ge, Philip J. Mason
Journal: Blood
Blood (2013) 122 (21): SCI-5.
https://doi.org/10.1182/blood.V122.21.SCI-5.SCI-5
Published: 2013
Journal Articles

Structure of the AML1-ETO eTAFH domain–HEB peptide complex and its contribution to AML1-ETO activity

Sangho Park, Wei Chen, Tomasz Cierpicki, Marco Tonelli, Xiongwei Cai, Nancy A. Speck, John H. Bushweller
Journal: Blood
Blood (2009) 113 (15): 3558–3567.
https://doi.org/10.1182/blood-2008-06-161307
Published: 2009
Includes: Supplemental data