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Arnaud Jacquel
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Journal Articles

Dasatinib Overcomes AML Resistance to BCL2 Inhibition By Indirectly Inhibiting MCL1: From Ex Vivo drug Sensitivity/Resistance Profiling to a Phase II Clinical Trial: A Hemato-BIO Study

Sylvain Garciaz, Rémy Castellano, Arnaud Jacquel, Arnaud Guille, Maxence Bourgoin, Camille Montersino, José Adélaïde, Patrick Auberger, Daniel Birnbaum, Marie Anne Hospital, Yves Collette, Norbert Vey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1378.
https://doi.org/10.1182/blood-2024-207352
Published: 2024
Journal Articles

BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1

Lorric Delage, Mireille Lambert, Émilie Bardel, Cindy Kundlacz, Dimitri Chartoire, Axel Conchon, Anne-Laure Peugnet, Lucas Gorka, Patrick Auberger, Arnaud Jacquel, Carole Soussain, Olivier Destaing, Henri-Jacques Delecluse, Susanne Delecluse, Samir Merabet, Alexandra Traverse-Glehen, Gilles Salles, Emmanuel Bachy, Marc Billaud, Hervé Ghesquières, Laurent Genestier, Jean-Pierre Rouault, Pierre Sujobert
Journal: Blood
Blood (2023) 141 (10): 1209–1220.
https://doi.org/10.1182/blood.2022016943
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

PKR-like Endoplasmic Reticulum Kinase Mediates Apoptosis Induced By Pharmacological AMP-Activated Protein Kinase Activation in Acute Myeloid Leukemia

Laury Poulain, PhD, Adrien Grenier, MD PhD, Johanna Mondesir, MD, Arnaud Jacquel, PhD, Claudie Bosc, Lucille Stuani, PhD, Rudy Birsen, MD, Sarah Mouche, Justine Decroocq, MD, Fetta Mazed, PhD, Benoit Viollet, PhD, Patrick Auberger, PhD, Pierre Sujobert, MD PhD, Didier Bouscary, MD PhD, Jean-Emmanuel Sarry, PhD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2552.
https://doi.org/10.1182/blood-2019-123364
Published: 2019
Journal Articles

Implication of the Anti-Apoptotic Protein Bcl-B (BCL2L10) in the Pathogenesis of Multiple Myeloma

Valentine Richez, Jr., MD, Frederic Luciano, PhD, Amine Hamouda, PhD, Alexandre Puissant, Guillaume Robert, PhD, Arnaud Jacquel, PhD, Thomas Cluzeau, MDPhD, Kenneth C Anderson, MD, Jean-Gabriel Fuzibet, MD, Patrick Auberger, PhD
Journal: Blood
Blood (2015) 126 (23): 2958.
https://doi.org/10.1182/blood.V126.23.2958.2958
Published: 2015
Journal Articles

PIM2 Pro-Survival Functions Are Mediated By RSK2 in AML

Marie-Anne Hospital, MD, Arnaud Jacquel, PhD, Alexa Green, Mireille Lambert, PhD, Patrick Auberger, PhD, Catherine Lacombe, Olivier Hermine, MD PhD, Ivan C Moura, PhD, Patrick Mayeux, PhD, Didier Bouscary, MD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2014) 124 (21): 912.
https://doi.org/10.1182/blood.V124.21.912.912
Published: 2014
Journal Articles

The P2Y6-AMPK Pathway Triggers Autophagy during CSF-1-Induced Human Monocyte Differentiation and Is a Potential Target in CMML

Sandrine Obba, PhDstudent, Zoheir Hizir, PhDstudent, Dorothée Selimoglu-Buet, PhD, Laurent Boyer, PhD, Anja Pfeifer, PhD, Mohamed-Amine Hamouda, PhDstudent, Diogo Goncalves, Michael Cerezo, PhDstudent, Sandrine Marchetti, PhD, Stephane Rocchi, PhD, Nathalie Droin, PhD, Guillaume Robert, PhD, Frederic Luciano, PhD, Bernard Robaye, PhD, Benoit Viollet, PhD, Laurence Legros, MD PhD, Eric Solary, MD PhD, Patrick Auberger, PhD, Arnaud Jacquel, PhD
Journal: Blood
Blood (2014) 124 (21): 4347.
https://doi.org/10.1182/blood.V124.21.4347.4347
Published: 2014
Journal Articles

cIAPs and XIAP reduce RIPKs to silence

Arnaud Jacquel, Patrick Auberger
Journal: Blood
Blood (2014) 123 (16): 2445–2446.
https://doi.org/10.1182/blood-2014-02-555771
Published: 2014
Journal Articles

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

Lise Willems, Nathalie Jacque, Arnaud Jacquel, Nathalie Neveux, Thiago Trovati Maciel, Mireille Lambert, Alain Schmitt, Laury Poulain, Alexa S. Green, Madalina Uzunov, Olivier Kosmider, Isabelle Radford-Weiss, Ivan Cruz Moura, Patrick Auberger, Norbert Ifrah, Valérie Bardet, Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2013) 122 (20): 3521–3532.
https://doi.org/10.1182/blood-2013-03-493163
Published: 2013
Includes: Supplemental data
Journal Articles

Autophagy is required for CSF-1–induced macrophagic differentiation and acquisition of phagocytic functions

Brief Report
Arnaud Jacquel, Sandrine Obba, Laurent Boyer, Maeva Dufies, Guillaume Robert, Pierre Gounon, Emmanuel Lemichez, Frederic Luciano, Eric Solary, Patrick Auberger
Journal: Blood
Blood (2012) 119 (19): 4527–4531.
https://doi.org/10.1182/blood-2011-11-392167
Published: 2012
Includes: Supplemental data
Journal Articles

Fine-tuning nucleophosmin in macrophage differentiation and activation

Leslie Guery, Naïma Benikhlef, Thomas Gautier, Catherine Paul, Gaetan Jego, Erick Dufour, Arnaud Jacquel, Radj Cally, Bénédicte Manoury, Tom Vanden Berghe, Peter Vandenabeele, Nathalie Droin, Eric Solary
Journal: Blood
Blood (2011) 118 (17): 4694–4704.
https://doi.org/10.1182/blood-2011-03-341255
Published: 2011
Includes: Supplemental data
Journal Articles

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia

Nathalie Droin, Arnaud Jacquel, Jean-Baptiste Hendra, Cindy Racoeur, Caroline Truntzer, Delphine Pecqueur, Naïma Benikhlef, Marion Ciudad, Leslie Guery, Valérie Jooste, Erick Dufour, Pierre Fenaux, Bruno Quesnel, Olivier Kosmider, Michaëla Fontenay, Patrick Ducoroy, Eric Solary
Journal: Blood
Blood (2010) 115 (1): 78–88.
https://doi.org/10.1182/blood-2009-05-224352
Published: 2010
Includes: Supplemental data
Journal Articles

Colony-stimulating factor-1–induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages

Arnaud Jacquel, Naïma Benikhlef, Jérôme Paggetti, Najoua Lalaoui, Leslie Guery, Erick K. Dufour, Marion Ciudad, Cindy Racoeur, Olivier Micheau, Laurent Delva, Nathalie Droin, Eric Solary
Journal: Blood
Blood (2009) 114 (17): 3633–3641.
https://doi.org/10.1182/blood-2009-03-208843
Published: 2009
Includes: Supplemental data
Journal Articles

The Histone Acetyl-Transferase MOZ Cooperates with the Histone Methyl-Transferase MLL to Regulate HOX Gene Expression in Human Hematopoietic Stem Cells

Jérôme Paggetti, Romain Aucagne, Arnaud Jacquel, PhD, Anne Largeot, Brice Lagrange, Eric Solary, MD, Jean-Noël Bastie, MD, PhD, Laurent Delva, PhD
Journal: Blood
Blood (2008) 112 (11): 2431.
https://doi.org/10.1182/blood.V112.11.2431.2431
Published: 2008
Journal Articles

Imatinib mesylate (STI571) decreases the vascular endothelial growth factor plasma concentration in patients with chronic myeloid leukemia

Laurence Legros, Christine Bourcier, Arnaud Jacquel, François-Xavier Mahon, Jill-Patrice Cassuto, Patrick Auberger, Gilles Pagès
Journal: Blood
Blood (2004) 104 (2): 495–501.
https://doi.org/10.1182/blood-2003-08-2695
Published: 2004