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Journal Articles

Rap-536, a Murine Luspatercept Analog Ameliorates Anemia and Vaso-Occlusion in Experimental Model of Sickle Cell Disease

Thiago Trovati Maciel, Haoua M Bazoum, Rachel Rignault-Bricard, Shikha Saini, Isabelle Chevalme, Sara El Hoss, Robert Li, Slimane Allali, Rajasekhar N.V.S. Suragani, Olivier Hermine

Blood (2024) 144 (Supplement 1): 621.

https://doi.org/10.1182/blood-2024-201454

Published: 2024

Journal Articles

Vexas Syndrome Is a New Cause of p53-Mediated Erythroblastopenia

François Rodrigues, Giulia Hardouin, Sara El Hoss, Aya Ghoul, Emilie-Fleur Gautier, Michael Dussiot, Sandy Peltier, Pascal Amireault, Annarita Miccio, Vincent Jachiet, Thiago Trovati Maciel, Sophie Georgin Lavialle, Julien Rossignol, Arsène Mekhinian, Olivier Kosmider, Manuel Rodriguez, Olivier Hermine

Blood (2024) 144 (Supplement 1): 36.

https://doi.org/10.1182/blood-2024-208122

Published: 2024

Journal Articles

Inhibition of the Complement Alternative Pathway Attenuates Hemolysis and Preserves Renal Function in a Mouse Model of Sickle Cell Disease

Thiago Trovati Maciel, Nabiha Sbeih, Rachel Rignault-Bricard, Isabelle Chevalme, Slimane Allali, Camille Brochier, Anna Kiialainen, Tovo David, Olivier Hermine

Blood (2024) 144 (Supplement 1): 2486.

https://doi.org/10.1182/blood-2024-207031

Published: 2024

Journal Articles

Complement Activation and Its Implication in the Pathophysiology of Hemolytic Anemia and Aging in Mouse Models of Sickle Cell Disease and Beta-Thalassemia

Thiago Trovati Maciel, Nabiha Sbeih, Rachel Rignault-Bricard, Isabelle Chevalme, Slimane Allali, Camille Brochier, Anna Kiialainen, Tovo David, Olivier Hermine

Blood (2024) 144 (Supplement 1): 3870.

https://doi.org/10.1182/blood-2024-207298

Published: 2024

Journal Articles

IMA001 Is a Novel Therapeutic Molecule That Improves Hematological Parameters during Vaso-Occlusion in Sickle Cell Disease In Vivo

Marielle Margier, Giulia Scorrano, Cecile Cros, Julie Charmetant, Thiago Trovati Maciel, Ousmane Alfa Cisse, Wassim El Nemer, Matthias Canault

Blood (2024) 144 (Supplement 1): 1103.

https://doi.org/10.1182/blood-2024-203501

Published: 2024

Journal Articles

Identifying News Genes Involved in Unexplained Erythrocytosis Throught a Clinical Database

Fabian Zanchetta-Balint, Nada Maaziz, Nicolas Garcelon, Valerie Cormier-Daire, Betty Gardie, Guillaume Canaud, Ilhem Rahal, Laure Joseph, Francois Lefrere, Stanislas Lyonnet, Thiago Trovati Maciel, Francois Girodon, Olivier Hermine

Blood (2024) 144 (Supplement 1): 5230.

https://doi.org/10.1182/blood-2024-206873

Published: 2024

Journal Articles

IMA001 Is a Novel Therapeutic Molecule That Reduces Sickling and Hemolytic Anemia Markers in a Sickle Cell Disease Mouse Model

Marielle Margier, Giulia Scorrano, Cecile Cros, Julie Charmetant, Thiago Trovati Maciel, Ousmane Alfa Cisse, Wassim El Nemer, Matthias Canault

Blood (2024) 144 (Supplement 1): 171.

https://doi.org/10.1182/blood-2024-199612

Published: 2024

Journal Articles

New Insights into Cellular Defects during Haematopoiesis of Sickle Cell Disease Using the Townes Mouse Model

Julien Grenier, Barbara Peyrard, Auria Godard, Julien Cheyrol, Thiago Trovati Maciel, Wassim El Nemer, Maria De Grandis

Blood (2023) 142 (Supplement 1): 3855.

https://doi.org/10.1182/blood-2023-181742

Published: 2023

Journal Articles

Sputum IL-6 Level Is a Potential Predictor and Severity Marker of Acute Chest Syndrome in Sickle Cell Disease

Slimane Allali, Juliette Elie, Mariane de Montalembert, Melissa Taylor, Joséphine Brice, Stéphanie Chhun, Rachel Rignault-Bricard, Claire Heilbronner, Thiago Trovati Maciel, Olivier Hermine

Blood (2022) 140 (Supplement 1): 8265.

https://doi.org/10.1182/blood-2022-166823

Published: 2022

Journal Articles

HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease

Slimane Allali, Rachel Rignault-Bricard, Mariane de Montalembert, Melissa Taylor, Tahar Bouceba, Olivier Hermine, Thiago Trovati Maciel

Blood (2022) 140 (18): 1972–1982.

https://doi.org/10.1182/blood.2021014894

Published: 2022

Includes: Supplemental data

Journal Articles

IMR-261, a Novel Oral Nrf2 Activator, Induces Fetal Hemoglobin in Human Erythroblasts, Reduces VOCs, and Ameliorates Ineffective Erythropoiesis in Experimental Mouse Models of Sickle Cell Disease and Beta-Thalassemia

Thiago Trovati Maciel, Caroline Carvalho, Rachel Rignault, Biree Andemariam, Betty S. Pace, Jennifer Isler OCain, Rahul Ballal

Blood (2021) 138 (Supplement 1): 853.

https://doi.org/10.1182/blood-2021-149528

Published: 2021

Journal Articles

PDE9 Inhibition By IMR-687 Improves Markers of Beta-Thalassemia in the Hbb th1/th1 Experimental Mouse Model

Thiago Trovati Maciel, Caroline Carvalho, Rachel Rignault, Slimane Allali, Biree Andemariam, Jennifer Isler OCain, Rahul Ballal

Blood (2021) 138 (Supplement 1): 945.

https://doi.org/10.1182/blood-2021-149481

Published: 2021

Journal Articles

Immune Profile of Sickle Cell Anemia Patients Treated with Allogeneic Stem Cell Transplantation

Julia Teixeira Cottas De Azevedo, MSc, Nathalia Ziegler de Oliveira, Keli Cristina de Lima, BSc, Thalita Cristina de Mello Costa, MD, Patrícia Vianna Bonini Palma, BSc, Dimas Tadeu Covas, MD PhD, Eduardo Donadi, Thiago Trovati Maciel, PhD, Olivier Hermine, MD PhD, Belinda Pinto Simões, MD PhD, Kelen Cristina Ribeiro Malmegrim, PhD

Blood (2017) 130 (Supplement 1): 5483.

https://doi.org/10.1182/blood.V130.Suppl_1.5483.5483

Published: 2017

Journal Articles

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Blood (2015) 126 (11): 1346–1356.

https://doi.org/10.1182/blood-2015-01-621870

Published: 2015

Includes: Supplemental data

Journal Articles

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

Blood (2013) 122 (20): 3521–3532.

https://doi.org/10.1182/blood-2013-03-493163

Published: 2013

Includes: Supplemental data

Journal Articles

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

Alexa S. Green, Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer, Valerie Bardet, Sophie Park, Marc Foretz, Benoit Viollet, Norbert Ifrah, François Dreyfus, Olivier Hermine, Ivan Cruz Moura, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, Jerome Tamburini

Blood (2010) 116 (20): 4262–4273.

https://doi.org/10.1182/blood-2010-02-269837

Published: 2010

Includes: Supplemental data

NARROW

Rap-536, a Murine Luspatercept Analog Ameliorates Anemia and Vaso-Occlusion in Experimental Model of Sickle Cell Disease

Vexas Syndrome Is a New Cause of p53-Mediated Erythroblastopenia

Inhibition of the Complement Alternative Pathway Attenuates Hemolysis and Preserves Renal Function in a Mouse Model of Sickle Cell Disease

Complement Activation and Its Implication in the Pathophysiology of Hemolytic Anemia and Aging in Mouse Models of Sickle Cell Disease and Beta-Thalassemia

IMA001 Is a Novel Therapeutic Molecule That Improves Hematological Parameters during Vaso-Occlusion in Sickle Cell Disease In Vivo

Identifying News Genes Involved in Unexplained Erythrocytosis Throught a Clinical Database

IMA001 Is a Novel Therapeutic Molecule That Reduces Sickling and Hemolytic Anemia Markers in a Sickle Cell Disease Mouse Model

New Insights into Cellular Defects during Haematopoiesis of Sickle Cell Disease Using the Townes Mouse Model

Sputum IL-6 Level Is a Potential Predictor and Severity Marker of Acute Chest Syndrome in Sickle Cell Disease

HbS promotes TLR4-mediated monocyte activation and proinflammatory cytokine production in sickle cell disease

IMR-261, a Novel Oral Nrf2 Activator, Induces Fetal Hemoglobin in Human Erythroblasts, Reduces VOCs, and Ameliorates Ineffective Erythropoiesis in Experimental Mouse Models of Sickle Cell Disease and Beta-Thalassemia

PDE9 Inhibition By IMR-687 Improves Markers of Beta-Thalassemia in the Hbb th1/th1 Experimental Mouse Model

Immune Profile of Sickle Cell Anemia Patients Treated with Allogeneic Stem Cell Transplantation

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

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American Society of Hematology

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American Society of Hematology

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