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Journal Articles

Rap-536, a Murine Luspatercept Analog Ameliorates Anemia and Vaso-Occlusion in Experimental Model of Sickle Cell Disease

Thiago Trovati Maciel, Haoua M Bazoum, Rachel Rignault-Bricard, Shikha Saini, Isabelle Chevalme, Sara El Hoss, Robert Li, Slimane Allali, Rajasekhar N.V.S. Suragani, Olivier Hermine
Journal: Blood
Blood (2024) 144 (Supplement 1): 621.
https://doi.org/10.1182/blood-2024-201454
Published: 2024
Journal Articles

Rap-536 (Murine ACE-536/Luspatercept) Inhibits Smad2/3 Signaling and Promotes Erythroid Differentiation By Restoring GATA-1 Function in Murine b-Thalassemia

Pedro A. Martinez, PhD, Rajasekhar NVS Suragani, PhD, Manoj Bhasin, PhD, Robert Li, Robert Scott Pearsall, PhD, Ravindra Kumar, PhD
Journal: Blood
Blood (2015) 126 (23): 751.
https://doi.org/10.1182/blood.V126.23.751.751
Published: 2015
Journal Articles

TGFb1 Antagonist Inhibits Fibrosis in a Murine Model of Myelofibrosis

Rajasekhar NVS Suragani, PhD, Pedro A. Martinez, PhD, Sharon M Cawley, PhD, Robert Li, Robert Scott Pearsall, PhD, Ravindra Kumar, PhD
Journal: Blood
Blood (2015) 126 (23): 605.
https://doi.org/10.1182/blood.V126.23.605.605
Published: 2015
Journal Articles

Modified Actriib-Fc Fusion Protein (ACE-536) Mitigates Sickling and Red Cell Pathology in a Murine Model of Sickle Cell Disease

Rajasekhar NVS Suragani, PhD, Robert Li, Sharon M Cawley, R. Scott Pearsall, Ravindra Kumar
Journal: Blood
Blood (2014) 124 (21): 4055.
https://doi.org/10.1182/blood.V124.21.4055.4055
Published: 2014
Journal Articles

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

Rajasekhar N. V. S. Suragani, Sharon M. Cawley, Robert Li, Samantha Wallner, Mark J. Alexander, Aaron W. Mulivor, Sara Gardenghi, Stefano Rivella, Asya V. Grinberg, R. Scott Pearsall, Ravindra Kumar
Journal: Blood
Blood (2014) 123 (25): 3864–3872.
https://doi.org/10.1182/blood-2013-06-511238
Published: 2014
Includes: Supplemental data
Journal Articles

Modified Activin Receptor Type IIb-Fc Fusion Protein (RAP-536) Decreases Anemia In a Murine Model Of Myelodysplastic Syndrome and Improves Overall Survival

Rajasekhar NVS Suragani, PhD, Robert Li, Sharon Cawley, R. Scott Pearsall, Ph.D., Ravi Kumar, Ph.D.
Journal: Blood
Blood (2013) 122 (21): 749.
https://doi.org/10.1182/blood.V122.21.749.749
Published: 2013
Journal Articles

ACE-536 Improves Ineffective Erythropoiesis, Anemia and Co-Morbidities in β-Thalassemia

Rajasekhar NVS Suragani, Robert Li, Sharon Cawley, Stefano Rivella, PhD, R. Scott Pearsall, Ravindra Kumar
Journal: Blood
Blood (2012) 120 (21): 248.
https://doi.org/10.1182/blood.V120.21.248.248
Published: 2012
Journal Articles

RAP-536 Promotes Terminal Erythroid Differentiation and Reduces Anemia in a Murine Model of Myelodysplastic Syndromes

Rajasekhar NVS Suragani, Robert Li, Dianne Sako, Asya Grinberg, R. Scott Pearsall, Ravindra Kumar
Journal: Blood
Blood (2012) 120 (21): 3796.
https://doi.org/10.1182/blood.V120.21.3796.3796
Published: 2012