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Journal Articles

Human Functional and Tunable in Vitro Model of Healthy and Multiple Myeloma Haematopoietic Niches

Mélanie Gadelorge, Caroline Siekaniec, Maria De Grandis, Frederic Deschaseaux, Jean-Gerard Descamps, Cécile Dromard, Wassim El Nemer, Marie Salon, Victorine Douin-Echinard, Agnes Coste, Nicolas Espagnolle

Blood (2024) 144 (Supplement 1): 2683.

https://doi.org/10.1182/blood-2024-199987

Published: 2024

Journal Articles

Lu/BCAM Expression Defines Functionally Distinct Red Blood Cells

Blood (2024) 144 (Supplement 1): 2454.

https://doi.org/10.1182/blood-2024-209794

Published: 2024

Journal Articles

Circulating Erythroblasts Are Associated with Specific Characteristics in Adult Patients with Sickle Cell Disease: The Drepablast Study

Ugo Boccadifuoco, Ivan Lerner, Auria Godard, Laure Joseph, Wassim El Nemer, Geoffrey Cheminet, Jean-Benoit Arlet

Blood (2024) 144 (Supplement 1): 3904.

https://doi.org/10.1182/blood-2024-205678

Published: 2024

Journal Articles

IMA001 Is a Novel Therapeutic Molecule That Improves Hematological Parameters during Vaso-Occlusion in Sickle Cell Disease In Vivo

Marielle Margier, Giulia Scorrano, Cecile Cros, Julie Charmetant, Thiago Trovati Maciel, Ousmane Alfa Cisse, Wassim El Nemer, Matthias Canault

Blood (2024) 144 (Supplement 1): 1103.

https://doi.org/10.1182/blood-2024-203501

Published: 2024

Journal Articles

IMA001 Is a Novel Therapeutic Molecule That Reduces Sickling and Hemolytic Anemia Markers in a Sickle Cell Disease Mouse Model

Marielle Margier, Giulia Scorrano, Cecile Cros, Julie Charmetant, Thiago Trovati Maciel, Ousmane Alfa Cisse, Wassim El Nemer, Matthias Canault

Blood (2024) 144 (Supplement 1): 171.

https://doi.org/10.1182/blood-2024-199612

Published: 2024

Journal Articles

Ineffective Erythropoiesis Negatively Impacts the Erythroblastic Island in Sickle Cell Disease

Auria Godard, Julien Grenier, Jonatane Andrieu, Sophie Beley, Pascale Poullin, Sandra Manceau, Laure Joseph, Maria De Grandis, Wassim El Nemer

Blood (2023) 142 (Supplement 1): 15.

https://doi.org/10.1182/blood-2023-181647

Published: 2023

Journal Articles

New Insights into Cellular Defects during Haematopoiesis of Sickle Cell Disease Using the Townes Mouse Model

Julien Grenier, Barbara Peyrard, Auria Godard, Julien Cheyrol, Thiago Trovati Maciel, Wassim El Nemer, Maria De Grandis

Blood (2023) 142 (Supplement 1): 3855.

https://doi.org/10.1182/blood-2023-181742

Published: 2023

Journal Articles

A Functional in Vitro 3D Model of Human Hematopoietic Niches

Melanie Gadelorge, Frederic Deschaseaux, Jean-Gerard Descamps, Alexandra Grimaldi, Pierre Layrolle, Agnes Coste, Wassim El Nemer, Maria De Grandis, Nicolas Espagnolle

Blood (2022) 140 (Supplement 1): 5778–5779.

https://doi.org/10.1182/blood-2022-162236

Published: 2022

Journal Articles

Revisiting Spleen Function and Pneumococcal Risk in Children with Hemoglobin SC Disease

Charlotte Pourdieu, Sara El Hoss, Enora Le Roux, Justine Pages, Berengere Koehl, Florence Missud, Laurent Holvoet, Ghislaine Ithier, Malika Benkerrou, Zine-Eddine Haouari, Lydie M. Da Costa, Wassim El Nemer, Yves Colin Aronovicz, Caroline Le Van Kim, Elodie Lainey, Valentine Brousse

Blood (2021) 138 (Supplement 1): 768.

https://doi.org/10.1182/blood-2021-150629

Published: 2021

Journal Articles

Base Editing-Mediated Dissection of the -200 Region of the γ-Globin Promoters to Induce Fetal Hemoglobin and Rescue Sickle Cell Disease and β-Thalassemia

Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci, Tristan Felix, Letizia Fontana, Jeanne Martin, Giacomo Frati, Megane Brusson, Marion Rosello, Giulia Maule, Filippo Del Bene, Anna Cereseto, Wassim El Nemer, Jean-Paul Concordet, Annarita Miccio

Blood (2021) 138 (Supplement 1): 562.

https://doi.org/10.1182/blood-2021-149710

Published: 2021

Journal Articles

Clinical Results of the Drepaglobe Trial for Sickle Cell Disease Patients

Blood (2021) 138 (Supplement 1): 1854.

https://doi.org/10.1182/blood-2021-152331

Published: 2021

Journal Articles

Fetal Hemoglobin Rescues Ineffective Erythropoiesis in Sickle Cell Disease

Sara El Hoss, PhD, Sylvie Cochet, Auria Godard, MS, Hongxia Yan, MS, Michaël Dussiot, PhD, Giacomo Frati, PhD, Bénédicte Boutonnat-Faucher, MD, Sandrine Laurance, PhD, Olivier Renaud, PhD, Laure Joseph, MD, Annarita Miccio, PhD, Valentine Brousse, MDPhD, Mohandas Narla, DSc, Wassim El Nemer, PhD

Blood (2020) 136 (Supplement 1): 14–15.

https://doi.org/10.1182/blood-2020-137477

Published: 2020

Journal Articles

Editing the LRF Repressor Binding Site in the γ-Globin Promoters Induces Therapeutically Relevant Fetal Hemoglobin Levels for the Treatment of β-Hemoglobinopathies

Giacomo Frati, PhD, Panagiotis Antoniou, MSc, Giulia Hardouin, Bochra Mlaya, MSc, Leslie Weber, Tristan Felix, Antonio Casini, Marion Rosello, Anne Chalumeau, Mario Amendola, Adrian J. Thrasher, MBBS, PhD FMedSci, Giandomenico Turchiano, PhD, Filippo Del Bene, Wassim El Nemer, PhD, Anna Cereseto, Jean-Paul Concordet, Carine Giovannangeli, Marina Cavazzana, MD PhD, Annarita Miccio, PhD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-139107

Published: 2020

Journal Articles

Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties

Yohann Garnier, Séverine Ferdinand, Marie Garnier, Kizzy-Clara Cita, Régine Hierso, Aurélie Claes, Philippe Connes, Marie-Dominique Hardy-Dessources, Claudine Lapouméroulie, Nathalie Lemonne, Maryse Etienne-Julan, Wassim El Nemer, Marc Romana

Blood (2020) 136 (2): 247–256.

https://doi.org/10.1182/blood.2020004853

Published: 2020

Includes: Supplemental data

Journal Articles

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Leslie Weber, Giacomo Frati, Tristan Felix, Clara Wollenschlaeger, Antonio Casini, Vasco Meneghini, Cecile Masson, Anne De Cian, Anne Chalumeau, Fulvio Mavilio, PhD, Mario Amendola, Isabelle André, PhD, Anna Cereseto, Wassim El Nemer, PhD, Jean-Paul Concordet, Carine Giovannangeli, Marina Cavazzana, Annarita Miccio, PhD

Blood (2019) 134 (Supplement_1): 4635.

https://doi.org/10.1182/blood-2019-123192

Published: 2019

Journal Articles

Results from the Completed Hgb-205 Trial of Lentiglobin for β-Thalassemia and Lentiglobin for Sickle Cell Disease Gene Therapy

Blood (2019) 134 (Supplement_1): 3358.

https://doi.org/10.1182/blood-2019-127393

Published: 2019

Journal Articles

Resolution of sickle cell disease–associated inflammation and tissue damage with 17 R -resolvin D1

Alessandro Matte, Antonio Recchiuti, Enrica Federti, Bérengère Koehl, Thomas Mintz, Wassim El Nemer, Pierre-Louis Tharaux, Valentine Brousse, Immacolata Andolfo, Alessia Lamolinara, Olga Weinberg, Angela Siciliano, Paul C. Norris, Ian R. Riley, Achille Iolascon, Charles N. Serhan, Carlo Brugnara, Lucia De Franceschi

Blood (2019) 133 (3): 252–265.

https://doi.org/10.1182/blood-2018-07-865378

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Analysis of RBC Properties in Patients with SCD Treated with Lentiglobin Gene Therapy

Nicolas Hebert, Elisa Magrin, PhD, Annarita Miccio, PhD, Kiger Laurent, PhD, Nguyen-Peyre Kim-Anh, PhD, Laure Joseph, MD, Alessandra Magnani, MD PhD, Chloé Couzin, MD, Wassim El Nemer, PhD, France Pirenne, MD PhD, Olivier Negre, PhD, Jean-Antoine Ribeil, MD PhD, Isabelle André-Schmutz, PhD, Pablo Bartolucci, MD PhD, Marina Cavazzana, MD PhD

Blood (2018) 132 (Supplement 1): 2195.

https://doi.org/10.1182/blood-2018-99-115973

Published: 2018

Journal Articles

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Antonio Rechiutti, Amtonella Panataleo, Roberta Russo, Francesco Turrini, MD PhD, Angela Siciliano, Pierre Louis Tharaux, MD PhD, Wassim El Nemer, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Wilson Babu, Achille Iolascon, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 725.

https://doi.org/10.1182/blood-2018-99-115832

Published: 2018

Journal Articles

Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus

Chiara Antoniani, Vasco Meneghini, Annalisa Lattanzi, Tristan Felix, Oriana Romano, Elisa Magrin, Leslie Weber, Giulia Pavani, Sara El Hoss, Ryo Kurita, Yukio Nakamura, Thomas J. Cradick, Ante S. Lundberg, Matthew Porteus, Mario Amendola, Wassim El Nemer, Marina Cavazzana, Fulvio Mavilio, Annarita Miccio

Blood (2018) 131 (17): 1960–1973.

https://doi.org/10.1182/blood-2017-10-811505

Published: 2018

Includes: Supplemental data

NARROW

Human Functional and Tunable in Vitro Model of Healthy and Multiple Myeloma Haematopoietic Niches

Lu/BCAM Expression Defines Functionally Distinct Red Blood Cells

Circulating Erythroblasts Are Associated with Specific Characteristics in Adult Patients with Sickle Cell Disease: The Drepablast Study

IMA001 Is a Novel Therapeutic Molecule That Improves Hematological Parameters during Vaso-Occlusion in Sickle Cell Disease In Vivo

IMA001 Is a Novel Therapeutic Molecule That Reduces Sickling and Hemolytic Anemia Markers in a Sickle Cell Disease Mouse Model

Ineffective Erythropoiesis Negatively Impacts the Erythroblastic Island in Sickle Cell Disease

New Insights into Cellular Defects during Haematopoiesis of Sickle Cell Disease Using the Townes Mouse Model

A Functional in Vitro 3D Model of Human Hematopoietic Niches

Revisiting Spleen Function and Pneumococcal Risk in Children with Hemoglobin SC Disease

Base Editing-Mediated Dissection of the -200 Region of the γ-Globin Promoters to Induce Fetal Hemoglobin and Rescue Sickle Cell Disease and β-Thalassemia

Clinical Results of the Drepaglobe Trial for Sickle Cell Disease Patients

Fetal Hemoglobin Rescues Ineffective Erythropoiesis in Sickle Cell Disease

Editing the LRF Repressor Binding Site in the γ-Globin Promoters Induces Therapeutically Relevant Fetal Hemoglobin Levels for the Treatment of β-Hemoglobinopathies

Plasma microparticles of sickle patients during crisis or taking hydroxyurea modify endothelium inflammatory properties

Editing a γ-Globin Repressor Binding Site Restores Fetal Hemoglobin Synthesis and Corrects the Phenotype of Sickle Cell Disease Erythrocytes

Results from the Completed Hgb-205 Trial of Lentiglobin for β-Thalassemia and Lentiglobin for Sickle Cell Disease Gene Therapy

Resolution of sickle cell disease–associated inflammation and tissue damage with 17 R -resolvin D1

Analysis of RBC Properties in Patients with SCD Treated with Lentiglobin Gene Therapy

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus

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American Society of Hematology

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American Society of Hematology

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