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Journal Articles

Single-Cell Transcriptomic Analysis of Bone Marrow from Humanized Sickle Cell Mice Reveals a Subpopulation of Highly-Expressing S100A8/A9 Mesenchymal Stem Cells

Jacopo Ceolan, Petros Kolovos, Enrica Federti, Panagiotis Liakopoulos, Veronica Riccardi, Immacolata Andolfo, Alessandro Mattè, Roberta Russo, Achille Iolascon, Helene Gleitz, Sjaak Philipsen, Lucia De Franceschi

Blood (2024) 144 (Supplement 1): 3867.

https://doi.org/10.1182/blood-2024-209911

Published: 2024

Journal Articles

Exploring Muscular Senescence in Transfusion-Dependent Thalassemia without Cardiac Iron Overload: Roles of FGF21, ICAM1 and Post-Exercise Pulmonary Congestion

Mattia Cominacini, Enrica Federti, Sofia Menotti, Martino Donini, Jacopo Ceolan, Simone Villaboni, Filippo Mazzi, Gianluigi Dorelli, Maria Teresa Valenti, Luca Dalle Carbonare, Lucia De Franceschi, Michele Braggio

Blood (2024) 144 (Supplement 1): 3858.

https://doi.org/10.1182/blood-2024-204793

Published: 2024

Journal Articles

pkm2 Binds to the Regulatory Regions of Gata-1 and stat5 in β-Thalassemic Mouse Erythroblasts

Enrica Federti, Silvia Pietrobono, Veronica Riccardi, Jacopo Ceolan, Richard Pozzetto Huot, Filippo Mazzi, Tolunay Kavaz, Immacolata Andolfo, Roberta Russo, Davide Melisi, Achille Iolascon, Lucia De Franceschi

Blood (2024) 144 (Supplement 1): 410.

https://doi.org/10.1182/blood-2024-203061

Published: 2024

Journal Articles

An oral carbon monoxide–releasing molecule protects against acute hyperhemolysis in sickle cell disease

Kim Anh Nguyen, Alessandro Matte, Roberta Foresti, Enrica Federti, Laurent Kiger, Cécile Lefebvre, Hakim Hocini, Yanis Pelinski, Hiroaki Kitagishi, Laura Bencheikh, France Pirenne, Lucia de Franceschi, Roberto Motterlini, Pablo Bartolucci

Blood (2024) 143 (24): 2544–2558.

https://doi.org/10.1182/blood.2023023165

Published: 2024

Includes: Supplemental data

Journal Articles

17R-Resolvin D1 Improves Inflammatory Cardiomyopathy in a Mouse Model of Sickle Cell Disease

Enrica Federti, Domenico Mattoscio, Antonio Recchiuti, Alessandro Mattè, Maria Monti, Flora Cozzolino, Martina Ceci, Manuela Iezzi, Angela Siciliano, Veronica Riccardi, Alice Passarini, Carlo Brugnara, Lucia De Franceschi

Blood (2023) 142 (Supplement 1): 2496.

https://doi.org/10.1182/blood-2023-185603

Published: 2023

Journal Articles

Colchicine Protects Against Cardiomyopathy in Humanized Mouse Model for Sickle Cell Disease

Enrica Federti, Iana Iatcenko, Alessandra Ghigo, Alessandro Mattè, Veronica Riccardi, Immacolata Andolfo, Angela Siciliano, Filippo Mazzi, Manuela Stella, Luigi Robbiano, Valeria Pinto, Achille Iolascon, Gian Luca Forni, Lucia De Franceschi

Blood (2022) 140 (Supplement 1): 2513–2514.

https://doi.org/10.1182/blood-2022-163037

Published: 2022

Journal Articles

Resolvins Modulate Netosis and Autoimmunity in Sickle Cell Disease

Alessandro Mattè, Antonio Recchiuti, Enrica Federti, Filippo Mazzi, Jacopo Ceolan, Annamaria Porreca, Marta Di Nicola, Sofia Menotti, Stefano Alivernini, Carlo Brugnara, Lucia De Franceschi

Blood (2022) 140 (Supplement 1): 5399–5400.

https://doi.org/10.1182/blood-2022-166240

Published: 2022

Journal Articles

Nrf2 Plays a Key Role in Iron-Overload Cardiomyopathy

Enrica Federti, Francesca Vinchi, Iana Iatcenko, Alessandra Ghigo, Alessandro Mattè, Serge Cedrick, Angela Siciliano, Deborah Chiabrando, Emanuela Tolosano, S. Zebulon Vance, Veronica Riccardi, Immacolata Andolfo, Achille Iolascon, Lucia de Franceschi

Blood (2021) 138 (Supplement 1): 3068.

https://doi.org/10.1182/blood-2021-146157

Published: 2021

Journal Articles

Mitapivat Improves Transfusion Burden and Reduces Iron Overload in Thalassemic Mice

Alessandro Mattè, Penelope A. Kosinski, Enrica Federti, Lenny Dang, Angela Siciliano, Iana Iatcenko, Carlo Brugnara, Lucia De Franceschi

Blood (2021) 138 (Supplement 1): 2016.

https://doi.org/10.1182/blood-2021-153721

Published: 2021

Journal Articles

The Pyruvate Kinase Activator Mitapivat Ameliorates Anemia and Prevents Iron Overload in a Mouse Model of Hereditary Spherocytosis

Alessandro Mattè, BSc,PhD, Wilson Anand, Enrica Federti, PhD, Charles Kung, PhD, Penelope A. Kosinski, MS, Veronica Riccardi, Iana Iatcenko, Lenny Dang, PhD, Christophe Leboeuf, Anne Janin, PhD, Carlo Brugnara, MD, Mohandas Narla, DSc, Lucia De Franceschi, MD

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-142232

Published: 2020

Journal Articles

Fyn Specifically Regulates the Activity of Red Cell Glucose-6-Phosphate-Dehydrogenase

Blood (2019) 134 (Supplement_1): 3527.

https://doi.org/10.1182/blood-2019-125709

Published: 2019

Journal Articles

The Novel Role That Nrf2 Plays in Erythropoiesis during Aging

Serge Cedrick Toya Mbiandjeu, Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Massimiliano Perduca, Immacolata Andolfo, Achille Iolascon, MD PhD, Maria Teresa Valenti, PhD, Arianna Pisani, Luca Dalle Carbonare, MD, Pietro Pucci, Angela Amoresano, Mohandas Narla, DSc, Lucia De Franceschi, MD

Blood (2019) 134 (Supplement_1): 3502.

https://doi.org/10.1182/blood-2019-125920

Published: 2019

Journal Articles

Resolution of sickle cell disease–associated inflammation and tissue damage with 17 R -resolvin D1

Alessandro Matte, Antonio Recchiuti, Enrica Federti, Bérengère Koehl, Thomas Mintz, Wassim El Nemer, Pierre-Louis Tharaux, Valentine Brousse, Immacolata Andolfo, Alessia Lamolinara, Olga Weinberg, Angela Siciliano, Paul C. Norris, Ian R. Riley, Achille Iolascon, Charles N. Serhan, Carlo Brugnara, Lucia De Franceschi

Blood (2019) 133 (3): 252–265.

https://doi.org/10.1182/blood-2018-07-865378

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Dietary Omega-3 Fatty Acid Supplementation Improves Sickle Cell Bone Disease By Affecting Osteoblastogenesis and Adipogenesis

Maria Teresa Valenti, PhD, Luca Dalle Carbonare, MD, Alessandro Mattè, BSc, PhD, Lorenzo Anez-Bustillos, Mark Puder, MD, Samuele Cheri, Michela Deiana, Enrica Federti, PhD, Serge Cedrick Toya Mbiandjeu, Angela Siciliano, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 2356.

https://doi.org/10.1182/blood-2018-99-115801

Published: 2018

Journal Articles

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Antonio Rechiutti, Amtonella Panataleo, Roberta Russo, Francesco Turrini, MD PhD, Angela Siciliano, Pierre Louis Tharaux, MD PhD, Wassim El Nemer, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Wilson Babu, Achille Iolascon, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 725.

https://doi.org/10.1182/blood-2018-99-115832

Published: 2018

Journal Articles

Reprogramming Cell-Signaling By Delivering the Catalytic Domain of Ptpgr Ameliorates Anemia of β-Thalassemia

Alessandro Mattè, PhD, Elisabetta Beneduce, Michela Mirenda, PhD, Roberta Russo, Achille Iolascon, MD PhD, Antonella Pantaleo, PhD, Francesco Turrini, MD PhD, Angela Siciliano, Enrica Federti, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Carlo Laudanna, MD, Lucia De Franceschi, MD

Blood (2017) 130 (Supplement 1): 2219.

https://doi.org/10.1182/blood.V130.Suppl_1.2219.2219

Published: 2017

Journal Articles

A Selective ORAL GLYT1 Inhibitor, Improves Anemia and RED CELL Survival in a MOUSE MODEL of Beta-Thalassemia

Carlo Brugnara, MD, Anja Harmeier, Lucia De Franceschi, MD, Alessandro Matte, Michael Winter, Annette Koerner, Omar Khwaja, Thomas Singer, Elisabetta Beneduce, Enrica Federti, Angela Siciliano

Blood (2016) 128 (22): 1284.

https://doi.org/10.1182/blood.V128.22.1284.1284

Published: 2016

Journal Articles

Peroxiredoxin-2: A Novel Factor Involved in Iron Homeostasis

Alessandro Mattè, PhD, Luigia De Falco, Enrica Federti, Sonia Levi, PhD, Achille Iolascon, MD PhD, Giorgia Federico, Narla Mohandas, DSc, Anne Janin, MD PhD, Mariasole Bruno, Christophe Leboeuf, PhD, Soo Young Choi, PhD, Dae Won Kim, Francesco Dima, MD, Angela Siciliano, Lucia De Franceschi, MD

Blood (2015) 126 (23): 406.

https://doi.org/10.1182/blood.V126.23.406.406

Published: 2015

Journal Articles

Resolvin D1 and Resolvin D2 Protect Against Hypoxia/Reoxygenation Induced Lung and Kidney Damage in a Sickle Cell Mouse Model of Acute Vaso-Occlusive Crisis

Alessandro Mattè, PhD, Antonio Recchiuti, PhD, Charles Serhan, PhD, Angela Siciliano, Enrica Federti, Olga Weinberg, MD, Brian Kalish, MD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2015) 126 (23): 966.

https://doi.org/10.1182/blood.V126.23.966.966

Published: 2015

Journal Articles

Dietary ω-3 Fatty Acid Supplementation As a Potential New Therapy for Vasculopathy in Sickle Cell Disease: Proof of Concept in a Transgenic Mouse Model

Brian T Kalish, MD, Alessandro Matte, PhD, Immacolata Andolfo, Achille Iolascon, Olga Weinberg, Angela Siciliano, Mrs, Enrica Federti, Mark Puder, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2014) 124 (21): 220.

https://doi.org/10.1182/blood.V124.21.220.220

Published: 2014

NARROW

Single-Cell Transcriptomic Analysis of Bone Marrow from Humanized Sickle Cell Mice Reveals a Subpopulation of Highly-Expressing S100A8/A9 Mesenchymal Stem Cells

Exploring Muscular Senescence in Transfusion-Dependent Thalassemia without Cardiac Iron Overload: Roles of FGF21, ICAM1 and Post-Exercise Pulmonary Congestion

pkm2 Binds to the Regulatory Regions of Gata-1 and stat5 in β-Thalassemic Mouse Erythroblasts

An oral carbon monoxide–releasing molecule protects against acute hyperhemolysis in sickle cell disease

17R-Resolvin D1 Improves Inflammatory Cardiomyopathy in a Mouse Model of Sickle Cell Disease

Colchicine Protects Against Cardiomyopathy in Humanized Mouse Model for Sickle Cell Disease

Resolvins Modulate Netosis and Autoimmunity in Sickle Cell Disease

Nrf2 Plays a Key Role in Iron-Overload Cardiomyopathy

Mitapivat Improves Transfusion Burden and Reduces Iron Overload in Thalassemic Mice

The Pyruvate Kinase Activator Mitapivat Ameliorates Anemia and Prevents Iron Overload in a Mouse Model of Hereditary Spherocytosis

Fyn Specifically Regulates the Activity of Red Cell Glucose-6-Phosphate-Dehydrogenase

The Novel Role That Nrf2 Plays in Erythropoiesis during Aging

Resolution of sickle cell disease–associated inflammation and tissue damage with 17 R -resolvin D1

Dietary Omega-3 Fatty Acid Supplementation Improves Sickle Cell Bone Disease By Affecting Osteoblastogenesis and Adipogenesis

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Reprogramming Cell-Signaling By Delivering the Catalytic Domain of Ptpgr Ameliorates Anemia of β-Thalassemia

A Selective ORAL GLYT1 Inhibitor, Improves Anemia and RED CELL Survival in a MOUSE MODEL of Beta-Thalassemia

Peroxiredoxin-2: A Novel Factor Involved in Iron Homeostasis

Resolvin D1 and Resolvin D2 Protect Against Hypoxia/Reoxygenation Induced Lung and Kidney Damage in a Sickle Cell Mouse Model of Acute Vaso-Occlusive Crisis

Dietary ω-3 Fatty Acid Supplementation As a Potential New Therapy for Vasculopathy in Sickle Cell Disease: Proof of Concept in a Transgenic Mouse Model

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American Society of Hematology

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American Society of Hematology

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