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Journal Articles

Macrophage metabolic rewiring improves heme-suppressed efferocytosis and tissue damage in sickle cell disease

Richa Sharma, Ada Antypiuk, S. Zebulon Vance, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi

Blood (2023) 141 (25): 3091–3108.

https://doi.org/10.1182/blood.2022018026

Published: 2023

Includes: Supplemental data

Journal Articles

Genetic Iron Overload Aggravates and Pharmacological Iron Restriction Improves MDS Pathophysiology in a Preclinical Mouse Model

S. Zebulon Vance, Ada Antypiuk, Richa Sharma, Franz Dürrenberger, Vania Manolova, Francesca Vinchi

Blood (2022) 140 (Supplement 1): 5341–5342.

https://doi.org/10.1182/blood-2022-170164

Published: 2022

Journal Articles

Heme and Iron Aggravate Tissue Damage in Sickle Cell Disease By Driving Macrophage Functional Reprogramming through the Coordinated Suppression of Efferocytosis and Mitochondrial Metabolism

Richa Sharma, S. Zebulon Vance, Ada Antypiuk, Deepa Manwani, Quentinn Pearce, James E. Cox, Xiuli An, Karina Yazdanbakhsh, Francesca Vinchi

Blood (2022) 140 (Supplement 1): 2456–2457.

https://doi.org/10.1182/blood-2022-165364

Published: 2022

Journal Articles

Nrf2 Plays a Key Role in Iron-Overload Cardiomyopathy

Enrica Federti, Francesca Vinchi, Iana Iatcenko, Alessandra Ghigo, Alessandro Mattè, Serge Cedrick, Angela Siciliano, Deborah Chiabrando, Emanuela Tolosano, S. Zebulon Vance, Veronica Riccardi, Immacolata Andolfo, Achille Iolascon, Lucia de Franceschi

Blood (2021) 138 (Supplement 1): 3068.

https://doi.org/10.1182/blood-2021-146157

Published: 2021