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Emanuela Tolosano
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Journal Articles

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

Carlo Castruccio Castracani, Laura Breda, Tyler Ellis Papp, Amaliris Guerra, Enrico Radaelli, Charles-Antoine Assenmacher, Giovanni Finesso, Barbara L Mui, Ying K. Tam, Simona Fontana, Chiara Riganti, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano, Hamideh Parhiz, Stefano Rivella
Journal: Blood
Blood blood.2024025846.
https://doi.org/10.1182/blood.2024025846
Published: 2024
Includes: Supplemental data
Journal Articles

An Erythroid-Specific Lentiviral Vector Improves Anemia and Iron Metabolism in a New Model of Xlsa

Carlo Castruccio Castracani, Laura Breda, Tyler E. Papp, Amaliris Guerra, Enrico Radaelli, Charles-Antoine Assenmacher, Giovanni Finesso, Barbara Mui, Ying K. Tam, Simona Fontana, Chiara Riganti, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano, Hamideh Parhiz, Stefano Rivella
Journal: Blood
Blood (2024) 144 (Supplement 1): 2195.
https://doi.org/10.1182/blood-2024-200747
Published: 2024
Journal Articles

Heme and macrophages: a complicated liaison

Emanuela Tolosano
Journal: Blood
Blood (2023) 141 (25): 3015–3017.
https://doi.org/10.1182/blood.2023020612
Published: 2023
Journal Articles

Nrf2 Plays a Key Role in Iron-Overload Cardiomyopathy

Enrica Federti, Francesca Vinchi, Iana Iatcenko, Alessandra Ghigo, Alessandro Mattè, Serge Cedrick, Angela Siciliano, Deborah Chiabrando, Emanuela Tolosano, S. Zebulon Vance, Veronica Riccardi, Immacolata Andolfo, Achille Iolascon, Lucia de Franceschi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3068.
https://doi.org/10.1182/blood-2021-146157
Published: 2021
Journal Articles

New Insights into Heme Utilization Pathways

Emanuela Tolosano, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-25.
https://doi.org/10.1182/blood-2019-121068
Published: 2019
Journal Articles

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation

Elisabetta Beneduce, Alessandro Mattè, PhD, Luigia De Falco, Serge Cedrick, Emanuela Tolosano, Deborah Chiabrando, Angela Siciliano, Achille Iolascon, MD PhD, Mohandas Narla, DSc, Lucia De Franceschi, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 9.
https://doi.org/10.1182/blood.V130.Suppl_1.9.9
Published: 2017
Journal Articles

Red Blood Cell Transfusions Shape Macrophages Towards an Anti-Inflammatory Functional Phenotype and Impair the Immune Response to Infectious Cues

Francesca Vinchi, Milene Costa da Silva, Richard Sparla, Heike Weidner, Martina Rauner, Emanuela Tolosano, Uwe Platzbecker, MD, Martina U. Muckenthaler
Journal: Blood
Blood (2017) 130 (Supplement 1): 227.
https://doi.org/10.1182/blood.V130.Suppl_1.227.227
Published: 2017
Journal Articles

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease

Francesca Vinchi, Milene Costa da Silva, Giada Ingoglia, Sara Petrillo, Nathan Brinkman, Adrian Zuercher, Adelheid Cerwenka, Emanuela Tolosano, Martina U. Muckenthaler
Journal: Blood
Blood (2016) 127 (4): 473–486.
https://doi.org/10.1182/blood-2015-08-663245
Published: 2016
Includes: Supplemental data
Journal Articles

The Heme Scavenger Hemopexin Reverts Heme-Driven Pro-Inflammatory Phenotypic Switching of Macrophages in Sickle Cell Disease

Francesca Vinchi, PhD, Milene Costa da Silva, PhDstudent, Giada Ingoglia, PhDstudent, Sara Petrillo, PhDstudent, Nathan Brinkman, Adrian Zuercher, Adelheid Cerwenka, PhD, Emanuela Tolosano, PhD, Martina U. Muckenthaler, PhD
Journal: Blood
Blood (2015) 126 (23): 2205.
https://doi.org/10.1182/blood.V126.23.2205.2205
Published: 2015
Journal Articles

Mitochondrial Heme Export Through FLVCR1b Controls Erythroid Differentiation.

Deborah Chiabrando, phD, Carlotta Giorgi, Lorenzo Silengo, MD, Fiorella Altruda, Paolo Pinton, Emanuela Tolosano
Journal: Blood
Blood (2012) 120 (21): 2090.
https://doi.org/10.1182/blood.V120.21.2090.2090
Published: 2012
Journal Articles

FLVCRb: a Mitochondrial FLVCR Isoform Important for Erythropoiesis

Deborah Chiabrando, phD, Student, Sonia Mercurio, phD, Student, Samuele Marro, PhD, Sharmila Fagoonee, PhD, Erika Messana, PhD, Emilia Turco, PhD, Lorenzo Silengo, PhD, Fiorella Altruda, PhD, Emanuela Tolosano
Journal: Blood
Blood (2010) 116 (21): 4243.
https://doi.org/10.1182/blood.V116.21.4243.4243
Published: 2010
Journal Articles

A New FLVCR Isoform Able to Support Erythropoiesis.

Deborah Chiabrando, Sonia Mercurio, Samuele Marro, Sharmila Fagoonee, Erika Messana, Emilia Turco, Lorenzo Silengo, Fiorella Altruda, Emanuela Tolosano
Journal: Blood
Blood (2009) 114 (22): 1080.
https://doi.org/10.1182/blood.V114.22.1080.1080
Published: 2009
Journal Articles

Haptoglobin modifies the hemochromatosis phenotype in mice

Brief Report
Emanuela Tolosano, Sharmila Fagoonee, Cinzia Garuti, Linda Valli, Nancy C. Andrews, Fiorella Altruda, Antonello Pietrangelo
Journal: Blood
Blood (2005) 105 (8): 3353–3355.
https://doi.org/10.1182/blood-2004-07-2814
Published: 2005
Journal Articles

Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis

Emanuela Tolosano, Sharmila Fagoonee, Emilio Hirsch, Franklin G. Berger, Heinz Baumann, Lorenzo Silengo, Fiorella Altruda
Journal: Blood
Blood (2002) 100 (12): 4201–4208.
https://doi.org/10.1182/blood-2002-04-1270
Published: 2002
Journal Articles

Defective Recovery and Severe Renal Damage After Acute Hemolysis in Hemopexin-Deficient Mice

Emanuela Tolosano, Emilio Hirsch, Enrico Patrucco, Clara Camaschella, Roberto Navone, Lorenzo Silengo, Fiorella Altruda
Journal: Blood
Blood (1999) 94 (11): 3906–3914.
https://doi.org/10.1182/blood.V94.11.3906
Published: 1999