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Journal Articles

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

Carlo Castruccio Castracani, Laura Breda, Tyler Ellis Papp, Amaliris Guerra, Enrico Radaelli, Charles-Antoine Assenmacher, Giovanni Finesso, Barbara L Mui, Ying K. Tam, Simona Fontana, Chiara Riganti, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano, Hamideh Parhiz, Stefano Rivella

Blood blood.2024025846.

https://doi.org/10.1182/blood.2024025846

Published: 2024

Includes: Supplemental data

Journal Articles

TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

Vania Lo Presti, Ding-wen Chen, Ana Martins, Pankaj Sharma, Yelena Ginzburg, Carlo Castruccio Castracani, Carla Casu, Ritama Gupta, Raffaella Gozzelino, Edward Behrens, Laura F Bennett, Robert Paulson, Peter Kurre, Stefano Rivella, Amaliris Guerra

Blood (2024) 144 (Supplement 1): 168.

https://doi.org/10.1182/blood-2024-212272

Published: 2024

Journal Articles

TFR2 Coordinates Erythroid Iron Availability and Erythropoietin Receptor Sensitivity By Monoferric Transferrin Forms

Amaliris Guerra, Pankaj Sharma, Xiuli An, Nermi L. Parrow, Robert E. Fleming, Yelena Ginzburg, Stefano Rivella

Blood (2024) 144 (Supplement 1): 2468.

https://doi.org/10.1182/blood-2024-211984

Published: 2024

Journal Articles

An Erythroid-Specific Lentiviral Vector Improves Anemia and Iron Metabolism in a New Model of Xlsa

Carlo Castruccio Castracani, Laura Breda, Tyler E. Papp, Amaliris Guerra, Enrico Radaelli, Charles-Antoine Assenmacher, Giovanni Finesso, Barbara Mui, Ying K. Tam, Simona Fontana, Chiara Riganti, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano, Hamideh Parhiz, Stefano Rivella

Blood (2024) 144 (Supplement 1): 2195.

https://doi.org/10.1182/blood-2024-200747

Published: 2024

Journal Articles

Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy

Blood (2024) 144 (15): 1633–1645.

https://doi.org/10.1182/blood.2023023349

Published: 2024

Includes: Supplemental data

Journal Articles

Differential Effect of Transferrin Lobe Iron Occupancy on a Murine Model of Inflammation

Nermi L. Parrow, Nisha Ajit George, Faris Ali, Nadia Wattad, Amaliris Guerra, Yelena Ginzburg, Stefano Rivella, Robert E. Fleming

Blood (2023) 142 (Supplement 1): 1095.

https://doi.org/10.1182/blood-2023-190984

Published: 2023

Journal Articles

Differential Effects of Monoferric Transferrin Forms on Erythropoiesis Are Mediated By TFR2

Amaliris Guerra, Ariel Rivera, Nolan Hamilton, Xiuli An, Nermi L. Parrow, Yelena Ginzburg, Robert E. Fleming, Stefano Rivella

Blood (2023) 142 (Supplement 1): 3846.

https://doi.org/10.1182/blood-2023-189107

Published: 2023

Journal Articles

Combination of a TGF-β Ligand Trap (RAP-GRL) and TMPRSS6 -ASO Is Superior for Correcting β-Thalassemia

Amaliris Guerra, Perry Demsko, Ariel Rivera, Carlo Castruccio Castracani, Laura Breda, Naoto Tanaka, Shuling Guo, Stefano Rivella

Blood (2022) 140 (Supplement 1): 1944–1945.

https://doi.org/10.1182/blood-2022-166801

Published: 2022

Journal Articles

The Effect of Monoferric Transferrins on Hypoferremia in a Murine Model of Inflammation

Nermi Parrow, Nisha George, Faris Ali, Nadia Wattad, Amaliris Guerra, Yelena Ginzburg, Stefano Rivella, Robert E Fleming

Blood (2022) 140 (Supplement 1): 2463–2464.

https://doi.org/10.1182/blood-2022-171130

Published: 2022

Journal Articles

Lnp-Targeting Hematopoietic Stem Cells and Lentiviral Gene Transfer to Generate and Rescue a Novel Mouse Model of Lethal Alpha-Thalassemia

Maxwell Chappell, Laura Breda, Danuta Jadwiga Jarocha, Michael Triebwasser, Tyler E Papp, Valentina Ghiaccio, Megan T Fedorky, Amaliris Guerra, Kandace Gollomp, Osheiza Y. Abdulmalik, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Hamideh Parhiz, Stefano Rivella

Blood (2022) 140 (Supplement 1): 300–302.

https://doi.org/10.1182/blood-2022-166621

Published: 2022

Journal Articles

TNFα and Anti-IFNγ Rescues Chronic Anemia of Inflammation Phenotype in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

Amaliris Guerra, Vania Lo Presti, Ding-Wen Chen, Ana Catarina Martins, Carlo Castruccio Castracani, Ritama Gupta, Laura Bennett, Raffaella Gozzelino, Robert Paulson, Peter Kurre, Stefano Rivella, Carla Casu

Blood (2022) 140 (Supplement 1): 5302–5303.

https://doi.org/10.1182/blood-2022-166643

Published: 2022

Journal Articles

Differential Effects of Monoferric Forms of Transferrin on Mouse Models of Anemia of Inflammation and Congenital Anemia

Amaliris Guerra, Ana Catarina Martins, Ariel Rivera, Nermi Parrow, Raffaella Gozzelino, Yelena Ginzburg, Robert E Fleming, Stefano Rivella

Blood (2022) 140 (Supplement 1): 8179–8180.

https://doi.org/10.1182/blood-2022-166391

Published: 2022

Journal Articles

Lack of IL6 Improves Recovery from Anemia of Inflammation Which Gets Hampered in Presence of Excess Iron

Sayantani Sinha, Ritama Gupta, Amaliris Guerra, Paige Mc Veigh, Sara Gardenghi, Carla Casu, Francesca Vinchi, Stefano Rivella

Blood (2021) 138 (Supplement 1): 3072.

https://doi.org/10.1182/blood-2021-153126

Published: 2021

Journal Articles

Improved Gene Therapy for Metachromatic Leukodystrophy

Lucas Tricoli, Adeline Vanderver, Laura Adang, Maxwell Chappell, Laura Breda, Naoto Tanaka, Michael Triebwasser, David Wenger, Danuta Jadwiga Jarocha, Amaliris Guerra, Lars Schlotawa, Karthikeyan Radhakrishnan, Rebecca Ahrens-Nicklas, Peter Kurre, Stephanie Hurwitz, Stefano Rivella

Blood (2021) 138 (Supplement 1): 3979.

https://doi.org/10.1182/blood-2021-150986

Published: 2021

Journal Articles

A Severe Mouse Model of Alpha-Thalassemia to Study Abnormal Iron Metabolism and Erythropoiesis, Hematopoietic Stem Cell Behavior and Development of a Gene Therapy Approach for Its Treatment

Maxwell Chappell, Danuta Jadwiga Jarocha, Laura Breda, Valentina Ghiaccio, Michael Triebwasser, Megan Fedorky, Amaliris Guerra, Kandace Gollomp, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Osheiza Abdulmalik, Stefano Rivella

Blood (2021) 138 (Supplement 1): 2012.

https://doi.org/10.1182/blood-2021-151217

Published: 2021

Journal Articles

Combination of a Luspatercept-like Drug (RAP-GRL) and Tmprss6 -ASO Is Superior to Either Drug Alone for Correcting β-Thalassemia

Amaliris Guerra, Perry Demsko, Paige McVeigh, Sayantani Sinha, Carlo Castruccio Castracani, Laura Breda, Carla Casu, Shuling Guo, Stefano Rivella

Blood (2021) 138 (Supplement 1): 2013.

https://doi.org/10.1182/blood-2021-151181

Published: 2021

Journal Articles

Obligate N-Terminal but Not C-Terminal Monoferric Transferrin Ameliorates Anemia in β-Thalassemic Mice

Amaliris Guerra, Nermi Parrow, Paige McVeigh, Robert E Fleming, Yelena Ginzburg, Stefano Rivella

Blood (2021) 138 (Supplement 1): 937.

https://doi.org/10.1182/blood-2021-152709

Published: 2021

Journal Articles

TNFα Controls the Delicate Balance between Erythropoiesis and Stem Cell Exhaustion during Inflammatory Stress

Amaliris Guerra, Vania Lo Presti, Ana Catarina Martins, Carlo Castruccio Castracani, Ritama Gupta, Rea Oikonomidou, Emir O'Hara, Carla Casu, Laura Bennett, Robert Paulson, Peter Kurre, Stefano Rivella, Raffaella Gozzelino

Blood (2021) 138 (Supplement 1): 2184.

https://doi.org/10.1182/blood-2021-152473

Published: 2021

Journal Articles

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Sayantani Sinha, PhD, Ritama Gupta, PhD, Jianbing Zhang, PhD, Amaliris Guerra, PhD, Ping La, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 940.

https://doi.org/10.1182/blood-2019-128826

Published: 2019

Journal Articles

Lobe specificity of iron binding to transferrin modulates murine erythropoiesis and iron homeostasis

Nermi L. Parrow, Yihang Li, Maria Feola, Amaliris Guerra, Carla Casu, Princy Prasad, Luke Mammen, Faris Ali, Edvinas Vaicikauskas, Stefano Rivella, Yelena Z. Ginzburg, Robert E. Fleming

Blood (2019) 134 (17): 1373–1384.

https://doi.org/10.1182/blood.2018893099

Published: 2019

Includes: Supplemental data

NARROW

An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA.

TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

TFR2 Coordinates Erythroid Iron Availability and Erythropoietin Receptor Sensitivity By Monoferric Transferrin Forms

An Erythroid-Specific Lentiviral Vector Improves Anemia and Iron Metabolism in a New Model of Xlsa

Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy

Differential Effect of Transferrin Lobe Iron Occupancy on a Murine Model of Inflammation

Differential Effects of Monoferric Transferrin Forms on Erythropoiesis Are Mediated By TFR2

Combination of a TGF-β Ligand Trap (RAP-GRL) and TMPRSS6 -ASO Is Superior for Correcting β-Thalassemia

The Effect of Monoferric Transferrins on Hypoferremia in a Murine Model of Inflammation

Lnp-Targeting Hematopoietic Stem Cells and Lentiviral Gene Transfer to Generate and Rescue a Novel Mouse Model of Lethal Alpha-Thalassemia

TNFα and Anti-IFNγ Rescues Chronic Anemia of Inflammation Phenotype in Tnfαko Mice Treated with Heat-Killed Brucella Abortus

Differential Effects of Monoferric Forms of Transferrin on Mouse Models of Anemia of Inflammation and Congenital Anemia

Lack of IL6 Improves Recovery from Anemia of Inflammation Which Gets Hampered in Presence of Excess Iron

Improved Gene Therapy for Metachromatic Leukodystrophy

A Severe Mouse Model of Alpha-Thalassemia to Study Abnormal Iron Metabolism and Erythropoiesis, Hematopoietic Stem Cell Behavior and Development of a Gene Therapy Approach for Its Treatment

Combination of a Luspatercept-like Drug (RAP-GRL) and Tmprss6 -ASO Is Superior to Either Drug Alone for Correcting β-Thalassemia

Obligate N-Terminal but Not C-Terminal Monoferric Transferrin Ameliorates Anemia in β-Thalassemic Mice

TNFα Controls the Delicate Balance between Erythropoiesis and Stem Cell Exhaustion during Inflammatory Stress

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Lobe specificity of iron binding to transferrin modulates murine erythropoiesis and iron homeostasis

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American Society of Hematology

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American Society of Hematology

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