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Maxwell Chappell
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Journal Articles

Lnp-Targeting Hematopoietic Stem Cells and Lentiviral Gene Transfer to Generate and Rescue a Novel Mouse Model of Lethal Alpha-Thalassemia

Maxwell Chappell, Laura Breda, Danuta Jadwiga Jarocha, Michael Triebwasser, Tyler E Papp, Valentina Ghiaccio, Megan T Fedorky, Amaliris Guerra, Kandace Gollomp, Osheiza Y. Abdulmalik, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Hamideh Parhiz, Stefano Rivella
Journal: Blood
Blood (2022) 140 (Supplement 1): 300–302.
https://doi.org/10.1182/blood-2022-166621
Published: 2022
Journal Articles

Establishment of High Titer Baboon Endogenous Retrovirus Envelope Pseudotyped Lentiviral Vector Production Protocol Focusing on Syncytium Formation and Exfoliation

Kazuhiro Noguchi, Yasuhiro Ikawa, Mika Takenaka, Yuta Sakai, Toshihiro Fujiki, Rie Kuroda, Maxwell Chappell, Valentina Ghiaccio, Stefano Rivella, Taizo Wada
Journal: Blood
Blood (2022) 140 (Supplement 1): 12987–12989.
https://doi.org/10.1182/blood-2022-163144
Published: 2022
Journal Articles

Improved Gene Therapy for Metachromatic Leukodystrophy

Lucas Tricoli, Adeline Vanderver, Laura Adang, Maxwell Chappell, Laura Breda, Naoto Tanaka, Michael Triebwasser, David Wenger, Danuta Jadwiga Jarocha, Amaliris Guerra, Lars Schlotawa, Karthikeyan Radhakrishnan, Rebecca Ahrens-Nicklas, Peter Kurre, Stephanie Hurwitz, Stefano Rivella
Journal: Blood
Blood (2021) 138 (Supplement 1): 3979.
https://doi.org/10.1182/blood-2021-150986
Published: 2021
Journal Articles

A Severe Mouse Model of Alpha-Thalassemia to Study Abnormal Iron Metabolism and Erythropoiesis, Hematopoietic Stem Cell Behavior and Development of a Gene Therapy Approach for Its Treatment

Maxwell Chappell, Danuta Jadwiga Jarocha, Laura Breda, Valentina Ghiaccio, Michael Triebwasser, Megan Fedorky, Amaliris Guerra, Kandace Gollomp, Nattiya Teawtrakul, Stavros Glentis, Antonis Kattamis, Osheiza Abdulmalik, Stefano Rivella
Journal: Blood
Blood (2021) 138 (Supplement 1): 2012.
https://doi.org/10.1182/blood-2021-151217
Published: 2021
Journal Articles

2'-O-Methoxyethyl Splice-Switching Oligos to Reverse Splicing from IVS2-745 β-Thalassemia Patient Cells: A Foundation for Potential Therapies

Valentina Ghiaccio, PhD, Alisa Dong, PhD, Irene Motta, MD, Shuling Guo, PhD, Raechel Peralta, MS, Susan M Freier, Andy Watt, Yasuhiro Ikawa, MD PhD, Maxwell Chappell, MS, Coralea Stephanou, PhD, Paola Delbini, PhD, Connie Chen, Soteroula Christou, MD, Marina Kleanthous, PhD, Kim Smith-Whitley, MD, Deepa Manwani, MD, Carla Casu, PhD, Maria Domenica Cappellini, MD, Osheiza Abdulmalik, DVM, Stefano Rivella, PhD, Laura Breda, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2244.
https://doi.org/10.1182/blood-2019-127017
Published: 2019