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Nicolas Hebert
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Journal Articles

Identification of HLA-Matched Related Donors for Hematopoietic Stem Cell Transplant in Adult Sickle Cell Patients: Experience from an Adult Referral Center in France

Gonzalo De Luna, Elham Harfouch, Arnaud Essaydi, Rabah Redjoul, Florence Beckerich, Elena Properzi, Nicolas Hebert, Anoosha Habibi, Geoffroy Volle, Marie Pierre Lehougre, Pablo Bartolucci, Sébastien Maury
Journal: Blood
Blood (2024) 144 (Supplement 1): 5361.
https://doi.org/10.1182/blood-2024-199973
Published: 2024
Journal Articles

Single Cell Hemoglobin Quantification Reveals HbF and HbS Increases in Sickle Erythrocytes from Patients Treated with Hydroxyurea

Laura Bencheikh, Laura Matabishi-Bibi, Gabriela Luszczewska, Meghan Perkins, Nicolas Hebert, Nagamy Rose Balli, Yosr Zaouali, Vincent Malcor Deydier De Pierrefeu, Fatima Bensiradj, Caroline Barau, France Pirenne, Carlo Brugnara, Martin H. Steinberg, Haydar Frangoul, Marie Cambot, Pablo Bartolucci
Journal: Blood
Blood (2024) 144 (Supplement 1): 1105.
https://doi.org/10.1182/blood-2024-209868
Published: 2024
Journal Articles

Oxygen Gradient Ektacytometry Is Associated with Markers of Hemolysis and Inflammation in a Large Sickle Cell Disease Cohort within the GenoMed4ALL Project

Amira Idrizovic, Marissa J.M. Traets, Anna Collado Gimbert, Sara Reidel, Sigrid van der Veen, Anne-Laure Pham Hung D'Alexandry D'Orengiani, Mirco D'Agnolo, Emmanuel Adu, Mickael MARIN, Emmanuelle Bourdelier, Elisabetta Mezzalira, Betzabel Cajiao Garcia, Santiago Zazo, Tiziana Sanavia, Cesare Rollo, David Beneitez, Bart J. Biemond, Erfan Nur, Karin Fijnvandraat, Saskia EM Schols, Anita W. Rijneveld, Marjon H. Cnossen, Aida Kidane, Nicolas Hebert, Maria Paola Boaro, Slimane Allali, Caroline Le van kim, Anna Ruiz Llobet, Béatrice Gulbis, Federico Alvarez, Piero Fariselli, Petros Kountouris, Raffaella Colombatti, Pablo Bartolucci, Mariane De Montalembert, Richard van Wijk, Eduard J. Van Beers, Maria del Mar Mañú-Pereira, Minke A.E. Rab
Journal: Blood
Blood (2024) 144 (Supplement 1): 290.
https://doi.org/10.1182/blood-2024-200639
Published: 2024
Journal Articles

Erythroid-Specific Chimerism Analysis after Allogeneic-Hematopoietic Stem Cell Transplantation Using a Human Leukocyte Antigen-Identical Sibling Donor in Sickle Cell Disease Patients

Gonzalo De Luna, Nicolas Hebert, Ivan Sloma, Florence Beckerich, Rabah Redjoul, Anoosha Habibi, Mathieu Leclerc, Vincent Parinet, Christine Robin, Cécile Pautas, Stephane Moutereau, Fatima Bensiradj, Meghan Perkins, France Pirenne, Dehbia Menouche, Pablo Bartolucci, Sébastien Maury
Journal: Blood
Blood (2024) 144 (Supplement 1): 4875.
https://doi.org/10.1182/blood-2024-209526
Published: 2024
Journal Articles

New Insights into VOC Incidence By Analyzing the Single Cell Quantification of HbF per RBC and Mchbs

Pablo Bartolucci, Laura Bencheikh, Meghan Perkins, Sophia Rapsode, Yosr Zaouali, Nicolas Hebert, Suella Martino, Fatima Bensiradj, Anoosha Habibi, Gonzalo De Luna, Marie Cambot
Journal: Blood
Blood (2023) 142 (Supplement 1): 5272.
https://doi.org/10.1182/blood-2023-184758
Published: 2023
Journal Articles

Neutron Spin Echo Spectroscopy Allows an Extremely Precise Evaluation of Hemoglobin S Structure and Dynamics, and Provides Insights on HbF Therapeutic Target

Nicolas Hebert, Laurent Kiger, Alexis Chenneviere, Anne-Laure Pham Hung D'Alexandry D'Orengiani, France Pirenne, Orsolya Czakke, Bela Farago, Lionel Porcar, Stephane Longeville, Pablo Bartolucci
Journal: Blood
Blood (2022) 140 (Supplement 1): 8245–8246.
https://doi.org/10.1182/blood-2022-158889
Published: 2022
Journal Articles

Fetal Hemoglobin Induced Improvement in Relative Age of Sickle Red Blood Cells Determined through Glycated Hemoglobin Assessment By Flow Cytometry

Nassima Djouder, Nicolas Hebert, Stephane Moutereau, Emmanuel Adu, Steeve Lowenski, Anne-Laure Pham Hung D'Alexandry D'Orengiani, France Pirenne, Carlosse Keumeugni, Corinne Duguet, Pablo Bartolucci
Journal: Blood
Blood (2022) 140 (Supplement 1): 8252–8253.
https://doi.org/10.1182/blood-2022-165435
Published: 2022
Journal Articles

Erythroid Chimerism Measurement As a Predictive Tool of Bone Marrow Transplantation Outcome in Sickle Cell Disease

Nicolas Hebert, Meghan Perkins, Ivan Sloma, Laura Bencheikh, Florence Beckerich, Rabah Redjoul, Stephane Moutereau, France Pirenne, Sébastien Maury, Gonzalo De Luna, Pablo Bartolucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 2028.
https://doi.org/10.1182/blood-2021-144844
Published: 2021
Journal Articles

Clinical Results of the Drepaglobe Trial for Sickle Cell Disease Patients

Elisa Magrin, Alessandra Magnani, Michaela Semeraro, Nicolas Hebert, Laure Joseph, Olivia Leblanc, Aurélie Gabrion, Cécile Roudaut, Axelle Maulet, Anne Chalumeau, Laurent Kiger, Jouda Marouene, Valérie Jolaine, Jean-Marc Treluyer, Ambroise Marçais, Felipe Suarez, Olivier Hermine, Fulvio Mavilio, Emmanuelle Six, Wassim El Nemer, Pablo Bartolucci, Annarita Miccio, Marina Cavazzana
Journal: Blood
Blood (2021) 138 (Supplement 1): 1854.
https://doi.org/10.1182/blood-2021-152331
Published: 2021
Journal Articles

Effects of BCL11A Shmir-Induced Post-Transcriptional Silencing on Hemoglobin Polymer Inhibition in Single Red Blood Cells at Physiologic Oxygen Tension

Daniel C. De Souza, Erica B. Esrick, Nicolas Hebert, Giuseppe Di Caprio, Marioara Ciuculescu, Emily Morris, Myriam Armant, Bronner P. Gonçalves, Ethan Schonbrun, Christian Brendel, David K. Wood, Pablo Bartolucci, David A. Williams, John M. Higgins
Journal: Blood
Blood (2021) 138 (Supplement 1): 964.
https://doi.org/10.1182/blood-2021-147314
Published: 2021
Journal Articles

Effects of BCL11A Shmir-Induced Post-Transcriptional Silencing on Distributions of HbF in Single-RBCs and Reticulocytes

Nicolas Hebert, Erica B. Esrick, Myriam Armant, Christian Brendel, Marioara Felicia Ciuculescu, Etienne Audureau, John M. Higgins, David A. Williams, Pablo Bartolucci
Journal: Blood
Blood (2021) 138 (Supplement 1): 967.
https://doi.org/10.1182/blood-2021-150186
Published: 2021
Journal Articles

Validation of BCL11A As Therapeutic Target in Sickle Cell Disease: Results from the Adult Cohort of a Pilot/Feasibility Gene Therapy Trial Inducing Sustained Expression of Fetal Hemoglobin Using Post-Transcriptional Gene Silencing

Erica B. Esrick, MD, Maureen Achebe, MD MPH, Myriam Armant, PhD, Pablo Bartolucci, MD PhD, Marioara Felicia Ciuculescu, MD, Heather Daley, Colleen Dansereau, MSN, RN, CPN, Giuseppe Di Caprio, PhD, Bronner Goncalves, MD PhD, Nicolas Hebert, Matthew M Heeney, MD, John M. Higgins, MD PhD, Leslie E. Lehmann, MD, John P Manis, MD, Olivier Negre, PhD, Sarah Nikiforow, MD PhD, Ethan Schonbrun, PhD, David K. Wood, PhD, David A. Williams, MD
Journal: Blood
Blood (2019) 134 (Supplement_2): LBA-5.
https://doi.org/10.1182/blood-2019-132745
Published: 2019
Journal Articles

Results from the Completed Hgb-205 Trial of Lentiglobin for β-Thalassemia and Lentiglobin for Sickle Cell Disease Gene Therapy

Elisa Magrin, PhD, Michaela Semeraro, MD PhD, Alessandra Magnani, MD PhD, Hervé Puy, MD PhD, Annarita Miccio, PhD, Nicolas Hebert, Jean-Sebastien Diana, MD, Francois Lefrere, MD, Felipe Suarez, MD PhD, Olivier Hermine, MD PhD, Valentine Brousse, MD, Catherine Poirot, MD PhD, Philippe Bourget, PharmD, PhD, Wassim El Nemer, PhD, Isabelle Guichard, MD, Despina Moshous, MD PhD, Benedicte Neven, MD, Fabrice Monpoux, MD, Marilyne Poirée, MD, Pablo Bartolucci, MD PhD, Jean-François Meritet, MD, David Grévent, MD, Thibaud Lefebvre, Pharm D.,PhD, Mohammed Asmal, MD PhD, Erin Whitney, MBA, Marisa Gayron, MS, Wenmei Huang, PhD MS, Isabelle Funck-Brentano, PsyD, Mariane de Montalembert, MD PhD, Laure Joseph, MD, Jean-Antoine Ribeil, MD PhD, Marina Cavazzana
Journal: Blood
Blood (2019) 134 (Supplement_1): 3358.
https://doi.org/10.1182/blood-2019-127393
Published: 2019
Journal Articles

Fetal Hemoglobin Measurement per Red Blood Cell Provides Biological and Clinical Protective Thresholds

Nicolas Hebert, Rakotoson Marie Georgine, PhD, Gwellaouen Bodivit, Etienne Audureau, MD PhD, Nadia Oubaya, Sadaf Pakdaman, Mehdi Sakka, Gaetana Di Liberto, PhD, Philippe Chadebech, PhD, Benoît Vingert, PhD, France Pirenne, MD PhD, Frédéric Galactéros, MD PhD, Marie Cambot, PhD, Pablo Bartolucci, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1008.
https://doi.org/10.1182/blood-2019-126727
Published: 2019
Journal Articles

Interest of a New Method for Free Plasma Heme Related Species Dosages in Sickle Cell Disease and Beta Thalassemia

Laurent Kiger, Sandia Adypagavane, Laura Bencheikh, PhD, Nicolas Hebert, Stephane Moutereau, MD, Frédéric Galactéros, MD PhD, Michael Marden, PhD, Yves Beuzard, MD, France Pirenne, MD PhD, Pablo Bartolucci, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3381.
https://doi.org/10.1182/blood-2019-130600
Published: 2019
Journal Articles

Analysis of RBC Properties in Patients with SCD Treated with Lentiglobin Gene Therapy

Nicolas Hebert, Elisa Magrin, PhD, Annarita Miccio, PhD, Kiger Laurent, PhD, Nguyen-Peyre Kim-Anh, PhD, Laure Joseph, MD, Alessandra Magnani, MD PhD, Chloé Couzin, MD, Wassim El Nemer, PhD, France Pirenne, MD PhD, Olivier Negre, PhD, Jean-Antoine Ribeil, MD PhD, Isabelle André-Schmutz, PhD, Pablo Bartolucci, MD PhD, Marina Cavazzana, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2195.
https://doi.org/10.1182/blood-2018-99-115973
Published: 2018
Journal Articles

A New Tool for HbF Quantification Demonstrates That Hydroxyurea Decreases Mostly RBCs Containing Very Low Amounts of HbF

Rakotoson Marie Georgine, Marie Cambot, Gwellaouen Bodivit, Gaetana Di Liberto, PhD, Philippe Chadebech, Nicolas Hebert, Benoit Vingert, PhD, Anoosha Habibi, MD, Sadaf Pakdaman, Alicia Jouard, France Pirenne, MD PhD, Frédéric Galactéros, MDPhD, Pablo Bartolucci, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3527.
https://doi.org/10.1182/blood.V130.Suppl_1.3527.3527
Published: 2017
Journal Articles

Proof of principle for transfusion of in vitro–generated red blood cells

Marie-Catherine Giarratana, Hélène Rouard, Agnès Dumont, Laurent Kiger, Innocent Safeukui, Pierre-Yves Le Pennec, Sabine François, Germain Trugnan, Thierry Peyrard, Tiffany Marie, Séverine Jolly, Nicolas Hebert, Christelle Mazurier, Nathalie Mario, Laurence Harmand, Hélène Lapillonne, Jean-Yves Devaux, Luc Douay
Journal: Blood
Blood (2011) 118 (19): 5071–5079.
https://doi.org/10.1182/blood-2011-06-362038
Published: 2011
Includes: Supplemental data