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Panagiotis Antoniou
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Journal Articles

Adenine base editor–mediated correction of the common and severe IVS1-110 (G>A) β-thalassemia mutation

Giulia Hardouin, Panagiotis Antoniou, Pierre Martinucci, Tristan Felix, Sandra Manceau, Laure Joseph, Cécile Masson, Samantha Scaramuzza, Giuliana Ferrari, Marina Cavazzana, Annarita Miccio
Journal: Blood
Blood (2023) 141 (10): 1169–1179.
https://doi.org/10.1182/blood.2022016629
Published: 2023
Includes: Supplemental data
Journal Articles

Two Is Better Than One: Fetal Hemoglobin Reactivation and Alpha-Globin Downregulation to Correct the β-Hemoglobinopathy Phenotype through Base Editing

Panagiotis Antoniou, Mathieu von Joest, Letizia Fontana, Giulia Hardouin, Pierre Martinucci, Marina Cavazzana, Annarita Miccio
Journal: Blood
Blood (2022) 140 (Supplement 1): 7788–7789.
https://doi.org/10.1182/blood-2022-166330
Published: 2022
Journal Articles

Targeted Base Editing Strategies for Beta-Hemoglobinopathies

Giulia Hardouin, Panagiotis Antoniou, Pierre Martinucci, Tristan Felix, Marta Zoccheddu, Anne Chalumeau, Giacomo Frati, Sandra Manceau, Laure Joseph, Oriana Romano, Marina Cavazzana, Annarita Miccio
Journal: Blood
Blood (2022) 140 (Supplement 1): 7778–7779.
https://doi.org/10.1182/blood-2022-162362
Published: 2022
Journal Articles

Base Editing-Mediated Dissection of the -200 Region of the γ-Globin Promoters to Induce Fetal Hemoglobin and Rescue Sickle Cell Disease and β-Thalassemia

Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci, Tristan Felix, Letizia Fontana, Jeanne Martin, Giacomo Frati, Megane Brusson, Marion Rosello, Giulia Maule, Filippo Del Bene, Anna Cereseto, Wassim El Nemer, Jean-Paul Concordet, Annarita Miccio
Journal: Blood
Blood (2021) 138 (Supplement 1): 562.
https://doi.org/10.1182/blood-2021-149710
Published: 2021
Journal Articles

Editing the LRF Repressor Binding Site in the γ-Globin Promoters Induces Therapeutically Relevant Fetal Hemoglobin Levels for the Treatment of β-Hemoglobinopathies

Giacomo Frati, PhD, Panagiotis Antoniou, MSc, Giulia Hardouin, Bochra Mlaya, MSc, Leslie Weber, Tristan Felix, Antonio Casini, Marion Rosello, Anne Chalumeau, Mario Amendola, Adrian J. Thrasher, MBBS, PhD FMedSci, Giandomenico Turchiano, PhD, Filippo Del Bene, Wassim El Nemer, PhD, Anna Cereseto, Jean-Paul Concordet, Carine Giovannangeli, Marina Cavazzana, MD PhD, Annarita Miccio, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33.
https://doi.org/10.1182/blood-2020-139107
Published: 2020