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Caroline Le Van Kim
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Journal Articles

Oxygen Gradient Ektacytometry Is Associated with Markers of Hemolysis and Inflammation in a Large Sickle Cell Disease Cohort within the GenoMed4ALL Project

Amira Idrizovic, Marissa J.M. Traets, Anna Collado Gimbert, Sara Reidel, Sigrid van der Veen, Anne-Laure Pham Hung D'Alexandry D'Orengiani, Mirco D'Agnolo, Emmanuel Adu, Mickael MARIN, Emmanuelle Bourdelier, Elisabetta Mezzalira, Betzabel Cajiao Garcia, Santiago Zazo, Tiziana Sanavia, Cesare Rollo, David Beneitez, Bart J. Biemond, Erfan Nur, Karin Fijnvandraat, Saskia EM Schols, Anita W. Rijneveld, Marjon H. Cnossen, Aida Kidane, Nicolas Hebert, Maria Paola Boaro, Slimane Allali, Caroline Le van kim, Anna Ruiz Llobet, Béatrice Gulbis, Federico Alvarez, Piero Fariselli, Petros Kountouris, Raffaella Colombatti, Pablo Bartolucci, Mariane De Montalembert, Richard van Wijk, Eduard J. Van Beers, Maria del Mar Mañú-Pereira, Minke A.E. Rab
Journal: Blood
Blood (2024) 144 (Supplement 1): 290.
https://doi.org/10.1182/blood-2024-200639
Published: 2024
Journal Articles

Defining Mechanistic Responses to Different Vaso-Occlusive Triggers in Sickle Cell Disease: A Step Towards Personalized VOC Reversal Strategies

Lucas F.S. Gushiken, Sarah Liane Linguet, Erica M.F. Gotardo, Pamela L Brito, Flavia C. Leonardo, Laetitia Claer, Slim Azouzi, Caroline Le Van Kim, Fernando Ferreira Costa, Sandrine Laurance, Berengere Khoel, Nicola Conran
Journal: Blood
Blood (2024) 144 (Supplement 1): 2489.
https://doi.org/10.1182/blood-2024-193820
Published: 2024
Journal Articles

Hydroxyurea's Impact on Erythropoiesis, Cell Death and HbF Expression in the Hudep-2 Model

Lea Kuznicki, Sandrine Laurance, Laetitia Claer, Caroline Le Van Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 2493.
https://doi.org/10.1182/blood-2023-177625
Published: 2023
Journal Articles

Single Cell Analysis and Functional Features of Circulating CD34 + Cells from Patients with Sickle Cell Anaemia Unveil a Defect in the Myeloid Lineage

Marion Serra, Patricia Hermand, Romain Duval, Carine Lefevre, Jade Merrer, Fallou Leye, Mohammad Salma, Marine Aglave, William Vainchenker, Caroline Le Van Kim, Slim Azouzi, Berengere Koehl
Journal: Blood
Blood (2023) 142 (Supplement 1): 1111.
https://doi.org/10.1182/blood-2023-180900
Published: 2023
Journal Articles

The Cs a and Cs b Red Cell Antigens of the Cost Blood Group Collection Correspond to the HNA-3a and HNA-3b Neutrophil Antigens: Unexpected Twins with Implications for Sickle Cell Anemia

Jonathan De Oliveira Rios, Alisa Soudry, Romain Duval, Alexandre Raneri, Thomas Poyot, Jérome Babinet, Mariane De Montalembert, Claudia Regina Bonini Domingos, Caroline Le Van Kim, Marc Romana, Thierry Peyrard, Slim Azouzi
Journal: Blood
Blood (2023) 142 (Supplement 1): 698.
https://doi.org/10.1182/blood-2023-178250
Published: 2023
Journal Articles

Genetic Evidence That Dimerization of Glycophorin a Is Critical for Red Cell Invasion By Plasmodium Falciparum but Not for the Binding of EBA-175

Slim Azouzi, Mahmoud Mikdar, Patricia Hermand-Tournamille, Kunal More, Sébastien Dechavanne, Romain Duval, Vincent Thonier, Caroline Le Van Kim, Isabelle Mouro-Chanteloup, Olivier Bertrand, Chetan Chitnis, Thierry Peyrard, Yves Colin Aronovicz
Journal: Blood
Blood (2022) 140 (Supplement 1): 2431.
https://doi.org/10.1182/blood-2022-165253
Published: 2022
Journal Articles

Adenosine Signaling Perturbs Erythropoiesis and Promotes Myeloid Differentiation

Mahmoud Mikdar, Marion Serra, Elia Colin, Yves Colin Aronovicz, Caroline Le Van Kim, Thierry Peyrard, Bérengère Koehl, Slim Azouzi
Journal: Blood
Blood (2021) 138 (Supplement 1): 1992.
https://doi.org/10.1182/blood-2021-146144
Published: 2021
Journal Articles

Persistence of Chronic Inflammation Despite Years of Transfusion Program in SCD Patients: Changing Red Blood Cells Is Not Sufficient to Treat Sickle Cell Disease

Abdoul Karim Dembele, Patricia Hermand-Tournamille, Florence Missud, Emmanuelle Lesprit, Malika Benkerrou, Caroline Le Van Kim, Berengere Koehl
Journal: Blood
Blood (2021) 138 (Supplement 1): 764.
https://doi.org/10.1182/blood-2021-147787
Published: 2021
Journal Articles

Revisiting Spleen Function and Pneumococcal Risk in Children with Hemoglobin SC Disease

Charlotte Pourdieu, Sara El Hoss, Enora Le Roux, Justine Pages, Berengere Koehl, Florence Missud, Laurent Holvoet, Ghislaine Ithier, Malika Benkerrou, Zine-Eddine Haouari, Lydie M. Da Costa, Wassim El Nemer, Yves Colin Aronovicz, Caroline Le Van Kim, Elodie Lainey, Valentine Brousse
Journal: Blood
Blood (2021) 138 (Supplement 1): 768.
https://doi.org/10.1182/blood-2021-150629
Published: 2021
Journal Articles

Inherited glycosylphosphatidylinositol defects cause the rare Emm-negative blood phenotype and developmental disorders

Romain Duval, Gaël Nicolas, Alexandra Willemetz, Yoshiko Murakami, Mahmoud Mikdar, Cedric Vrignaud, Hisham Megahed, Jean-Pierre Cartron, Cecile Masson, Samer Wehbi, Bérengere Koehl, Marie Hully, Karine Siquier, Nicole Chemlay, Agnes Rotig, Stanislas Lyonnet, Yves Colin, Giulia Barcia, Vincent Cantagrel, Caroline Le Van Kim, Olivier Hermine, Taroh Kinoshita, Thierry Peyrard, Slim Azouzi
Journal: Blood
Blood (2021) 137 (26): 3660–3669.
https://doi.org/10.1182/blood.2020009810
Published: 2021
Includes: Supplemental data
Journal Articles

The equilibrative nucleoside transporter ENT1 is critical for nucleotide homeostasis and optimal erythropoiesis

Mahmoud Mikdar, Pedro González-Menéndez, Xiaoli Cai, Yujin Zhang, Marion Serra, Abdoul K. Dembele, Anne-Claire Boschat, Sylvia Sanquer, Cerina Chhuon, Ida Chiara Guerrera, Marc Sitbon, Olivier Hermine, Yves Colin, Caroline Le Van Kim, Sandrina Kinet, Narla Mohandas, Yang Xia, Thierry Peyrard, Naomi Taylor, Slim Azouzi
Journal: Blood
Blood (2021) 137 (25): 3548–3562.
https://doi.org/10.1182/blood.2020007281
Published: 2021
Includes: Supplemental data
Journal Articles

Rapid clearance of storage-induced microerythrocytes alters transfusion recovery

Camille Roussel, Alexandre Morel, Michaël Dussiot, Mickaël Marin, Martin Colard, Aurélie Fricot-Monsinjon, Anaïs Martinez, Charlotte Chambrion, Benoît Henry, Madeleine Casimir, Geoffroy Volle, Mallorie Dépond, Safi Dokmak, François Paye, Alain Sauvanet, Caroline Le Van Kim, Yves Colin, Sonia Georgeault, Philippe Roingeard, Steven L. Spitalnik, Papa Alioune Ndour, Olivier Hermine, Eldad A. Hod, Pierre A. Buffet, Pascal Amireault
Journal: Blood
Blood (2021) 137 (17): 2285–2298.
https://doi.org/10.1182/blood.2020008563
Published: 2021
Includes: Supplemental data
Journal Articles

Persistance of Inflammatory Phenotype of Neutrophils in Sickle Cell Disease Children Despite Chronic Exchange Transfusion Program: A Cause of the Progression of Cerebral Vasculopathy?

Abdoul Karim Dembele, MD, Patricia Hermand-Tournamille, PhD, Florence Missud, MD, Emmanuelle Lesprit, MD, Malika Benkerrou, MD, Yves Colin Aronovicz, PhD, Caroline Le Van Kim, PhD, Bérengère Koehl, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-136098
Published: 2020
Journal Articles

Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation

Slim Azouzi, Mahmoud Mikdar, Patricia Hermand, Emilie-Fleur Gautier, Virginie Salnot, Alexandra Willemetz, Gaël Nicolas, Cédric Vrignaud, Alexandre Raneri, Patrick Mayeux, Christine Bole‐Feysot, Patrick Nitschké, Jean-Pierre Cartron, Yves Colin, Olivier Hermine, Gabriele Jedlitschky, Marc Cloutier, Jessica Constanzo-Yanez, Carole Ethier, Nancy Robitaille, Maryse St-Louis, Caroline Le Van Kim, Thierry Peyrard
Journal: Blood
Blood (2020) 135 (6): 441–448.
https://doi.org/10.1182/blood.2019002320
Published: 2020
Includes: Supplemental data
Journal Articles

CELL-Derived Microparticles and Sickle CELL Disease Chronic Vasculopathy in Sub-Saharan Africa

Abdoul Karim Dembele, MD, Claudine Lapoumeroulie, PhD, Mor Diaw, PhD, Oumar Tessougué, MD, Lucile Offredo, MS, Dapa Aly Diallo, MD, Saliou Diop, MD MSc, Jacques Elion, MD PhD, Yves Colin Aronovicz, Pierre Louis Tharaux, MD PhD, Xavier Jouven, MD PhD, Marc Romana, PhD, Brigitte Ranque, MD PhD, Caroline Le Van Kim, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3568.
https://doi.org/10.1182/blood-2019-121334
Published: 2019
Journal Articles

Studying the Determinant of Sickle Cell Disease Vasculopathy in Sub-Saharan Africa : The Biocadre Study

Brigitte Ranque, Abdoul Karim Dembele, MD, Mor Diaw, PhD, Claudine Lapoumeroulie, PhD, Lucile Offredo, MS, Dapa Aly Diallo, MD, Diop Saliou, MD, Yves Colin Aronovicz, PhD, Olivier Blanc Brude, PhD, Philippe Connes, PhD, Pierre-Louis Tharaux, MD PhD, Marc Romana, PhD, Xavier Jouven, MD PhD, Caroline Le Van Kim, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2310.
https://doi.org/10.1182/blood-2019-126713
Published: 2019
Journal Articles

The Multidrug Transporter MRP4/ABCC4 Involved in the Leukemia Clinical Course Specifies the Novel PEL Human Blood Group System

Slim Azouzi, PhD, Mahmoud Mikdar, MSc, Patricia Hermand-Tournamille, PhD, Emilie-Fleur Gautier, PhD, Virginie Salnot, PhD, Alexandra Willemetz, MSc, Gaël Nicolas, PhD, Cedric Vrignaud, MSc, Alexandre Raneri, Patrick Mayeux, PhD, Christine Bole-Feysot, PhD, Patrick Nitschke, PhD, Jean-Pierre Cartron, PhD, Yves Colin Aronovicz, PhD, Olivier Hermine, Gabriele Jedlitschky, PhD, Marc Cloutier, PhD, Jessica Constanzo-Yanez, Carole Ethier, Nancy Robitaille, MD, Maryse St-Louis, Caroline Le Van Kim, PhD, Thierry Peyrard, PharmD/PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 715.
https://doi.org/10.1182/blood-2019-124082
Published: 2019
Journal Articles

Storage-Induced Micro-Erythrocytes Are Rapidly Cleared from Recipient Circulation and Predict Transfusion Recovery

Camille Roussel, MD PhD, Alexandre Morel, MD, Michaël Dussiot, PhD, Mickael MARIN, Martin Colard, MD, Aurélie Fricot, Anaïs Martinez, Charlotte Chambrion, Benoît Henry, MD PhD, Geoffroy Volle, Mallorie Depond, Safi Dokmak, MD, Francois Paye, MD, Alain Sauvanet, MD, Caroline Le Van Kim, PhD, Yves Colin Aronovicz, PhD, Steven L. Spitalnik, MD, Papa Alioune Ndour, PhD, Eldad A. Hod, MD, Olivier Hermine, MD PhD, Pierre Buffet, MD PhD, Pascal Amireault, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 717.
https://doi.org/10.1182/blood-2019-128161
Published: 2019
Journal Articles

New Insights into F-Cells, F-Reticulocytes and the Role of Fetal Hemoglobin in Protecting Sickle Red Cells from Hemolysis upon Mechanical Stress

Sara El Hoss, Maria Alejandra Lizarralde Iragorri, Valentine Brousse, MD, Michaël Dussiot, PhD, Sophie Lefevre, PhD, Alexander Rodrigo Ferreira, Yann Lamarre, PhD, Ana Cristina Silva Pinto, MD PhD, Simone Kashima, PhD, Claudine Lapoumeroulie, PhD, Dimas Tadeu Covas, MD PhD, Caroline Le Van Kim, PhD, Yves Colin Aronovicz, PhD, Jacques Elion, MD PhD, Olivier Français, PhD, Bruno Le Pioufle, PhD, Wassim El Nemer, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3513.
https://doi.org/10.1182/blood.V130.Suppl_1.3513.3513
Published: 2017
Journal Articles

Comparative Proteomics and Functional Analysis of Red Blood Cell Membrane Proteins in the Rare in(Lu) Blood Type

Slim Azouzi, PhD, Mahmoud Mikdar, MSc, Sara El Hoss, Alexandra Willemetz, MSc, Emilie-fleur Gautier, PhD, Patrick Mayeux, PhD, Wassim El Nemer, PhD, Yves Colin, PhD, Caroline Le Van Kim, PhD, Thierry Peyrard, PhD PharmD
Journal: Blood
Blood (2017) 130 (Supplement 1): 934.
https://doi.org/10.1182/blood.V130.Suppl_1.934.934
Published: 2017