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Journal Articles

Defining therapeutic chimerism thresholds for comprehensive sickle cell disease correction in the townes mouse model

Nicole Mende, Sandra Marbach, Diana Robles Diaz, Jordan Poirot, Mukul Girotra, Francois Christen, Larissa Brosi, Solveig Badillo, Chaimae El Houjjaji, Josep Monne, Martina Stirn, Tovo David

Blood (2025) 146 (Supplement 1): 4700.

https://doi.org/10.1182/blood-2025-4700

Published: 2025

Journal Articles

Preclinical evaluation of SPK-8011QQ, an adeno-associated virus gene therapy for people with hemophilia A leveraging the dirloctocogene samoparvovec platform encoding an activated Protein C-resistant B-domain deleted factor VIII

Nina Frey, Nicolas Receveur, Michel Enderlin-Paput, Emmeline Blanchard, Hayley Hanby, Julia Ramos, Tovo David

Blood (2025) 146 (Supplement 1): 1068.

https://doi.org/10.1182/blood-2025-1068

Published: 2025

Journal Articles

Novel CD117 T-cell engagers for targeted bone marrow HSPC depletion

Mukul Girotra, Evelyn Sauer, Ouliana Barneoud-Rousset, Diana Robles Diaz, Jordan Poirot, Nicole Mende, Sandra Marbach, Friederike Jung, Sebastian Seibold, Alexander Fidler, Carolina Ballester-Lopez, Nicolas Receveur, Birgit Kittel, Jason Neale, Tovo David

Blood (2025) 146 (Supplement 1): 2305.

https://doi.org/10.1182/blood-2025-2305

Published: 2025

Journal Articles

Complement Activation and Its Implication in the Pathophysiology of Hemolytic Anemia and Aging in Mouse Models of Sickle Cell Disease and Beta-Thalassemia

Thiago Trovati Maciel, Nabiha Sbeih, Rachel Rignault-Bricard, Isabelle Chevalme, Slimane Allali, Camille Brochier, Anna Kiialainen, Tovo David, Olivier Hermine

Blood (2024) 144 (Supplement 1): 3870.

https://doi.org/10.1182/blood-2024-207298

Published: 2024

Journal Articles

Preclinical Evaluation of NXT007 Using in Vitro and In Vivo Models of Hemostasis and Thrombosis

Matthew Locke, Jamie Jessica Albiez, Nicolas Receveur, Sandra Marbach, Nina Frey, Mukul Girotra, Mariella Wyssenbach, Lejla Bektic, Tovo David

Blood (2024) 144 (Supplement 1): 1199.

https://doi.org/10.1182/blood-2024-193496

Published: 2024

Journal Articles

Inhibition of the Complement Alternative Pathway Attenuates Hemolysis and Preserves Renal Function in a Mouse Model of Sickle Cell Disease

Thiago Trovati Maciel, Nabiha Sbeih, Rachel Rignault-Bricard, Isabelle Chevalme, Slimane Allali, Camille Brochier, Anna Kiialainen, Tovo David, Olivier Hermine

Blood (2024) 144 (Supplement 1): 2486.

https://doi.org/10.1182/blood-2024-207031

Published: 2024

Journal Articles

Transcriptomic Analysis Shows a Common Multi-Organ Inflammatory/Complement Signature in Hemolysis-Induced Damage

Julie Peliconi, Julien Lavergne, Camille Brochier, Florent Guinot, Tovo David, Lubka T Roumenina, Anne Grunenwald

Blood (2024) 144 (Supplement 1): 2644.

https://doi.org/10.1182/blood-2024-201529

Published: 2024

Journal Articles

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

Joni M. Prasad, Oleg V. Gorkun, Harini Raghu, Sherry Thornton, Eric S. Mullins, Joseph S. Palumbo, Ya-Ping Ko, Magnus Höök, Tovo David, Shaun R. Coughlin, Jay L. Degen, Matthew J. Flick

Blood (2015) 126 (17): 2047–2058.

https://doi.org/10.1182/blood-2015-04-639849

Published: 2015

Includes: Supplemental data

Journal Articles

TMEM16F Ion Channel Regulates Calcium-Dependent PS Exposure, Hemostasis, and Thrombosis

Andrew Y. Kim, PhD, Huanghe Yang, PhD, Tovo David, PhD, Jason Tien, Shaun R Coughlin, PhD, Yuh Nung Jan, Ph.D., Lily Jan, PhD

Blood (2012) 120 (21): 1111.

https://doi.org/10.1182/blood.V120.21.1111.1111

Published: 2012

Journal Articles

Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome

Bojing Shao, Mark G. Wahrenbrock, Longbiao Yao, Tovo David, Shaun R. Coughlin, Lijun Xia, Ajit Varki, Rodger P. McEver

Blood (2011) 118 (15): 4015–4023.

https://doi.org/10.1182/blood-2011-07-368514

Published: 2011

Journal Articles

Identification of a novel 14-3-3ζ binding site within the cytoplasmic tail of platelet glycoprotein Ibα

Pierre Mangin, Tovo David, Vincent Lavaud, Susan L. Cranmer, Inna Pikovski, Shaun P. Jackson, Michael C. Berndt, Jean-Pierre Cazenave, Christian Gachet, François Lanza

Blood (2004) 104 (2): 420–427.

https://doi.org/10.1182/blood-2003-08-2881

Published: 2004

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Defining therapeutic chimerism thresholds for comprehensive sickle cell disease correction in the townes mouse model

Preclinical evaluation of SPK-8011QQ, an adeno-associated virus gene therapy for people with hemophilia A leveraging the dirloctocogene samoparvovec platform encoding an activated Protein C-resistant B-domain deleted factor VIII

Novel CD117 T-cell engagers for targeted bone marrow HSPC depletion

Complement Activation and Its Implication in the Pathophysiology of Hemolytic Anemia and Aging in Mouse Models of Sickle Cell Disease and Beta-Thalassemia

Preclinical Evaluation of NXT007 Using in Vitro and In Vivo Models of Hemostasis and Thrombosis

Inhibition of the Complement Alternative Pathway Attenuates Hemolysis and Preserves Renal Function in a Mouse Model of Sickle Cell Disease

Transcriptomic Analysis Shows a Common Multi-Organ Inflammatory/Complement Signature in Hemolysis-Induced Damage

Mice expressing a mutant form of fibrinogen that cannot support fibrin formation exhibit compromised antimicrobial host defense

TMEM16F Ion Channel Regulates Calcium-Dependent PS Exposure, Hemostasis, and Thrombosis

Carcinoma mucins trigger reciprocal activation of platelets and neutrophils in a murine model of Trousseau syndrome

Identification of a novel 14-3-3ζ binding site within the cytoplasmic tail of platelet glycoprotein Ibα

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American Society of Hematology

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