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Carole Soussain
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Journal Articles

Trial in Progress: An Open-Label Expansion Trial Evaluating the Safety, PK/PD, and Clinical Activity of Emavusertib (CA-4948) + Ibrutinib in R/R Primary CNS Lymphoma

Christian Grommes, Grzegorz S. Nowakowski, Allison C. Rosenthal, Matthew A Lunning, Radhakrishnan Ramchandren, Lucia Regales, Meaghan Fowle, Maureen Lane, Catherine Wang, Antonio Omuro, Lori A. Leslie, Carole Soussain, Anna Paulina Dabrowska-Iwanicka, Andrés José María Ferreri, Han Tun
Journal: Blood
Blood (2023) 142 (Supplement 1): 3143.
https://doi.org/10.1182/blood-2023-190391
Published: 2023
Journal Articles

Highly Sensitive Interleukin Score for Intra-Ocular Lymphoma Diagnosis: Evidence from Analysis of 5-Year Real-Life of Use

Elise Sourdeau, Martin Chevalier, Hélène Masse, Julie Gueudry, Yann Maucourant, Marie-Laure Le Lez, Philippe Gohier, Marie Alice Laville, Nathalie Cassoux, Fatma Abid Mzid, Mohamed Ali Gargouri, Marie Marechal, Guido Ahle, Clotilde Devin, Sara Touhami, Valerie Touitou, Caroline Houillier, Khe Hoang-Xuan, Choquet Sylvain, Carole Soussain, Adélaïde Toutee, Magali Le Garff-Tavernier
Journal: Blood
Blood (2023) 142 (Supplement 1): 3002.
https://doi.org/10.1182/blood-2023-182192
Published: 2023
Journal Articles

BTG1 inactivation drives lymphomagenesis and promotes lymphoma dissemination through activation of BCAR1

Lorric Delage, Mireille Lambert, Émilie Bardel, Cindy Kundlacz, Dimitri Chartoire, Axel Conchon, Anne-Laure Peugnet, Lucas Gorka, Patrick Auberger, Arnaud Jacquel, Carole Soussain, Olivier Destaing, Henri-Jacques Delecluse, Susanne Delecluse, Samir Merabet, Alexandra Traverse-Glehen, Gilles Salles, Emmanuel Bachy, Marc Billaud, Hervé Ghesquières, Laurent Genestier, Jean-Pierre Rouault, Pierre Sujobert
Journal: Blood
Blood (2023) 141 (10): 1209–1220.
https://doi.org/10.1182/blood.2022016943
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Impact on Tumour Treatment and Outcome of Sars-Cov-2 Infection in 91 Patients with Primary CNS Lymphoma: A Real-Life Study of the International PCNSL Collaborative Group

Teresa Calimeri, Sara Steffanoni, Alice Laurenge, Christopher P. Fox, Carole Soussain, Christian Grommes, Maria Chiara Tisi, Jesca Boot, Nicola Crosbie, Carlo Visco, Luca Arcaini, Sridhar Chaganti, Alvaro J. Alencar, Daniele Armiento, Ilaria Romano, Marianna C. Sassone, Jorg Dietrich, Gilad Itchaki, Riccardo Bruna, Nicola S Fracchiolla, Laura Arletti, Adriano Venditti, Stephen Booth, Pellegrino Musto, Khe Hoang-Xuan, Tracy Batchelor, Kate Cwynarski, Andrés J.M. Ferreri
Journal: Blood
Blood (2022) 140 (Supplement 1): 3785–3787.
https://doi.org/10.1182/blood-2022-167915
Published: 2022
Journal Articles

Trial in Progress: A Phase 1b/2 Study of GB5121, a Brain-Penetrant, Potent, Highly Selective, and Irreversible BTK Inhibitor for Relapsed/Refractory Primary/Secondary CNS Lymphoma and Primary Vitreoretinal Lymphoma

Carole Soussain, Samar Issa, Katharine L Lewis, Christian Grommes, Judith Fox, Renee Ward, Caryn Peterson, Matt Cravets, Anita Mathias, Judith Sosa, Brian J Kirby, Zhaoqing Ding, Isharat Yusuf, Mark J Rose, Marcos W Steinberg, Han W. Tun
Journal: Blood
Blood (2022) 140 (Supplement 1): 12068–12069.
https://doi.org/10.1182/blood-2022-158599
Published: 2022
Journal Articles

Efficacy of CAR-T Cells in Primary Central Nervous System Lymphomas: The French Experience of the National LOC Network

Choquet Sylvain, Magali Le Garff-Tavernier, Laetitia Souchet, Damien Roos Weil, Veronique Morel, Madalina Uzunov, Carole Metz, Stephanie Nguyen Quoc, Nathalie Jacque, Nicolas Gauthier, Lise Willems, Agathe Waultier, Celia Salanoubat, Roch Houot, Renata Ursu, Maryline Barrie, Guido Ahle, Carole Soussain, Marion Alcantara, Caroline Houillier
Journal: Blood
Blood (2022) 140 (Supplement 1): 7540–7541.
https://doi.org/10.1182/blood-2022-167784
Published: 2022
Journal Articles

Timing of high-dose methotrexate CNS prophylaxis in DLBCL: a multicenter international analysis of 1384 patients

Matthew R. Wilson, Toby A. Eyre, Amy A. Kirkwood, Nicole Wong Doo, Carole Soussain, Sylvain Choquet, Nicolás Martinez-Calle, Gavin Preston, Matthew Ahearne, Elisabeth Schorb, Marie-Pierre Moles-Moreau, Matthew Ku, Chiara Rusconi, Jahanzaib Khwaja, Mayur Narkhede, Katharine L. Lewis, Teresa Calimeri, Eric Durot, Loïc Renaud, Andreas Kiesbye Øvlisen, Graham McIlroy, Timothy J. Ebsworth, Johnathan Elliot, Anna Santarsieri, Laure Ricard, Nimish Shah, Qin Liu, Adam S. Zayac, Francesco Vassallo, Laure Lebras, Louise Roulin, Naelle Lombion, Kate Manos, Ruben Fernandez, Nada Hamad, Alberto Lopez-Garcia, Deirdre O'Mahony, Praveen Gounder, Nathalie Forgeard, Charlotte Lees, Kossi Agbetiafa, Tim Strüßmann, Thura Win Htut, Aline Clavert, Hamish Scott, Anna Guidetti, Brett R. Barlow, Emmanuelle Tchernonog, Jeffery Smith, Fiona Miall, Christopher P. Fox, Chan Y. Cheah, Tarec Christoffer El Galaly, Andrés J.M. Ferreri, Kate Cwynarski, Pamela McKay
Journal: Blood
Blood (2022) 139 (16): 2499–2511.
https://doi.org/10.1182/blood.2021014506
Published: 2022
Includes: Supplemental data
Journal Articles

CAR T-cell therapy in primary central nervous system lymphoma: the clinical experience of the French LOC network

Clinical Trials & Observations
Marion Alcantara, Caroline Houillier, Marie Blonski, Marie-Thérèse Rubio, Lise Willems, Agathe Waultier Rascalou, Magali Le Garff-Tavernier, Karim Maloum, Clotilde Bravetti, Laetitia Souchet, Damien Roos-Weil, Véronique Morel, Madalina Uzunov, Carole Metz, Meriem Dhib-Charfi, Stéphanie Nguyen, Natalia Shor, Dimitri Psimaras, Nicolas Weiss, Nathalie Jacque, Silvia Solorzano, Nicolas Gauthier, Marie Le Cann, Françoise Norol, Carole Soussain, Sylvain Choquet
Journal: Blood
Blood (2022) 139 (5): 792–796.
https://doi.org/10.1182/blood.2021012932
Published: 2022
Includes: Supplemental data
Journal Articles

Radiotherapy (WBRT) or Autologous Stem-Cell Transplantation (ASCT) for Primary CNS Lymphoma in Patients 60 Years of Age and Younger: Long-Term Results of the Intergroup Anocef-Goelams Randomized Phase II Precis Study

Caroline Houillier, Luc Taillandier, Roch Houot, Olivier Chinot, Cecile Molucon-Chabrot, Anna Schmitt, Rémy Gressin, Choquet Sylvain, Gandhi Laurent Damaj, Julie Abraham, Vincent Delwail, Emmanuel Gyan, Sylvain Dureau, Laurence Sanhes, Jérôme Cornillon, Reda Garidi, Alain Delmer, Marie-laure Tanguy, Ahmad Kanj AL Jijakli, Pierre Morel, Marie-Pierre Moles, Adrien Chauchet, Thomas Gastinne, Loïc Feuvret, Nathalie Cassoux, Valerie Touitou, Damien Ricard, Frédéric Peyrade, Mouna Laadhari, Anne-Sophie Plissonnier, Khe Hoang-Xuan, Carole Soussain
Journal: Blood
Blood (2021) 138 (Supplement 1): 658.
https://doi.org/10.1182/blood-2021-146389
Published: 2021
Journal Articles

Early Integration of High Dose Methotrexate to Frontline DLBCL Therapy Does Not Impact CNS Relapse Compared to End of Treatment Delivery: A Multicentre International Analysis of 1384 Patients

Matthew R Wilson, Toby A. Eyre, Amy A Kirkwood, Nicole Wong Doo, Carole Soussain, Sylvain Choquet, Nicolas Martinex-Calle, Gavin Preston, Matthew J Ahearne, Elisabeth Schorb, Marie-Pierre Moles-Moreau, Matthew Ku, Chiara Rusconi, Jahanzaib Khwaja, Mayur Narkhede, Katharine L Lewis, Teresa Calimeri, Eric Durot, Loic Renaud, Andreas Kiesbye Øvlisen, Graham McIlroy, Tim Ebsworth, Johnathon Elliot, Anna Santarsiere, Laure Ricard, Nimish Shah, Qin Liu, Adam Zayac, Francesco Vassallo, Laure Lebras, Louise Roulin, Naelle Lombion, Kate Manos, Ruben Fernandez, Nada Hamad, Alberto Lopez-Garcia, Deirdre O'Mahony, Praveen Gounder, Nathalie Forgeard, Charlotte Lees, Kossi Agbetiafa, Tim Strüßmann, Thura Win Htut, Aline Clavert, Hamish W Scott, Anna Guidetti, Brett R Barlow, Jeffrey Smith, Tarec Christoffer El-Galaly, Chan Yoon Cheah, Andres JM Ferreri, Fiona Miall, Christopher P Fox, Kate Cwynarski, Pamela McKay
Journal: Blood
Blood (2021) 138 (Supplement 1): 452.
https://doi.org/10.1182/blood-2021-144820
Published: 2021
Journal Articles

Primary vitreoretinal lymphoma: a diagnostic and management challenge

Carole Soussain, Denis Malaise, Nathalie Cassoux
Journal: Blood
Blood (2021) 138 (17): 1519–1534.
https://doi.org/10.1182/blood.2020008235
Published: 2021
Includes: Supplemental data
Journal Articles

First Results of the Acsé Pembrolizumab Phase II in the Primary CNS Lymphoma (PCNSL) Cohort

Khe Hoang-Xuan, MDPhD, Roch Houot, MDPhD, Carole Soussain, MD PhD, Marie Blonski, MD, Anna Schmitt, MD, Vincent Delwail, MD, Gandhi Laurent Damaj, MD PhD, Herve Ghesquieres, MD PhD, Frédéric Peyrade, MD, Adrian Tempescul, MD, Julie Abraham, MD, Philippe Agape, MD, Guido Ahle, MD, Nathalie Baize, MD, Pierre Bories, MD, Chantal Campello, MD, Emmanuel Gyan, MD PhD, Fabrice Jardin, MD PhD, Philippe Rey, MD, Sylvain Choquet, MD, Caroline Houillier, MD, Nathalie Cassoux, MDPhD, Valerie Touitou, MDPhD, Nadine Martin-Duverneuil, MD, Frederic Legrand, Assia Lamrani-Ghaouti, Ophelie Querel, Natalie Hoog Labouret, MD, Clotilde Simon, Sylvie Chevret, MDPhD, Christophe Massard, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-141773
Published: 2020
Journal Articles

Temozolomide is effective and well tolerated in patients with primary vitreoretinal lymphoma

Clinical Trials & Observations
Marine Baron, Lisa Belin, Nathalie Cassoux, Christine Fardeau, Marion Blaizeau, Carole Soussain, Caroline Houillier, Khê Hoang-Xuan, Emmanuel Gyan, Marie-Laure Le Lez, Anne Lavaud, Pierre Soubeyran, Bahram Bodaghi, Myrto Costopoulos, Véronique Leblond, Valérie Touitou, Karim Maloum, Marie-Hélène Errera, Damien Roos-Weil, Magali Le Garff-Tavernier, Sylvain Choquet
Journal: Blood
Blood (2020) 135 (20): 1811–1815.
https://doi.org/10.1182/blood.2019003073
Published: 2020
Journal Articles

Primary Diffuse Large B-Cell CNS Lymphoma over 80 Years: An Analysis of 110 Patients from the French Oculo-Cerebral Lymphoma (LOC) Network

Alizee Maarek, MD, Delphine Maucort-Boulch, MD PhD, Caroline Houillier, MD, Olivier Chinot, MD PhD, Fontanet Bijou, MD, Luc Taillandier, MD PhD, Philippe Agape, MD, Roch Houot, MD PhD, Eileen Boyle, MD, Cecile Molucon-Chabrot, MD PhD, Philippe Rey, MD, Sylvain Choquet, MD, Jerome Tamburini Bonnefoy, MD PhD, Arnaud Jaccard, MD PhD, Guido Ahle, MD, Michel Fabbro, MD, Anne-Claire Gac, MD, Jean-Come Meniane, MD, Marie Francoise Le Coz, MD, Emmanuel Gyan, MD PhD, Khe Hoang-Xuan, MD PhD, Carole Soussain, MD PhD, Herv Ghesquieres
Journal: Blood
Blood (2018) 132 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2018-99-117331
Published: 2018
Journal Articles

Primary CNS Lymphomas (PCNSL) Patient-Derived Xenograft (PDX) Models Capture the Biological and Molecular Characteristics of the Disease

Frederic Pouzoulet, PhD, Agusti Alentorn, MD, Mailys Daniau, PhD, Karima Mokhtari, MD, Magali Le Garff-Tavernier, Frederic Davi, MD PhD, Matthieu Peyre, MD, Franck Assayag, Ingeneer, Dalila Labiod, Ingeneer, Khe Hoang-xuan, MD PhD, Carole Soussain, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4104.
https://doi.org/10.1182/blood.V130.Suppl_1.4104.4104
Published: 2017
Journal Articles

Ibrutinib: A Risk Factor for Invasive Fungal Infections?

Rosa Ruchlemer, MD, Ronen Ben Ami, MD, Maskit Bar-Meir, Jennifer R. Brown, MD PhD, Marion Malphettes, MD, Rogier Mous, MD PhD, Sanne Tonino, MD PhD, Carole Soussain, MD PhD, Noelie Barzic, Julia A. Messina, MD, Preetesh Jain, MBBS,MDDM,PhD, Regev Cohen, MD, Brian T. Hill, MD PhD, Stephen Mulligan, PhDFRACP,FRCPA,MBBS, Marcel Nijland, MD, Yair Herishanu, MD, Ohad Benjamini, MD, Tamar Tadmor, MD, Koh Okamoto, MD, Benjamin Arthurs, MD, Jacob M. Rowe, MB, BS, Tamar Lachish, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4323.
https://doi.org/10.1182/blood.V130.Suppl_1.4323.4323
Published: 2017
Journal Articles

Keep an Eye on CXCL-13: A Promising Biomarker to Help IL-10 and IL-6 for the Diagnosis of Intraocular Lymphomas

Chloe Friedrich, Myrto Costopoulos, PharmD, Gregory Lazarian, PharmD, Choquet Sylvain, Martine Brissard, Caroline Houillier, MD, Nathalie Cassoux, MD PhD, Carole Soussain, MD PhD, Veronique Leblond, Helene Merle-Beral, MD PhD, Valerie Touitou, MD PhD, Magali Le Garff-Tavernier
Journal: Blood
Blood (2017) 130 (Supplement 1): 2841.
https://doi.org/10.1182/blood.V130.Suppl_1.2841.2841
Published: 2017
Journal Articles

Temozolomide in Relapse/Refractory Primary Vitreo-Retinal Lymphoma (R/R PVRL): A New Effective, Well-Tolerated and Cheap Reference. Result of a Study on Behalf of the LOC Network

Choquet Sylvain, Marine Baron, Anne Lavaud, Carole Soussain, MD PhD, Valerie Touitou, MD PhD, Christine Fardeau, Nathalie Cassoux, MD PhD, Magali Le Garff-Tavernier, Mirto Costopoulos, Caroline Houillier, MD, Karim Maloum, Véronique Leblond, Emmanuel Gyan, MDPhD, Pierre Soubeyran, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2845.
https://doi.org/10.1182/blood.V130.Suppl_1.2845.2845
Published: 2017
Journal Articles

Efficacy and Safety of Intensive Etoposide Aracytine Consolidation Following Rituximab Methotrexate Temozolomide Induction in Newly Diagnosed Primary Central Nervous System Lymphoma

Rudy Birsen, Estelle Blanc, MD, Barbara Burroni, MD, Chloe Broudin, MD, Lise Willems, MD, Marielle Legoff, MD, Emmanuelle Leray, MD, Sylvain Pilorge, MD, Sawsen Salah, MD, Aude Quentin, MD, Bénédicte Deau-Fisher, MD, Patricia Franchi, MD, Marguerite Vignon, MD, Laurence Mabille, MD, Charles Nguyen, MD, Youlia Kirova, MD, Pascale Varlet, MD, Arnault tauziede-Espariat, MD, Myriam Edjlali, MD, Dezamis Edouard, MD, Carole Soussain, MD PhD, Caroline Houillier, MD, Johan Pallud, MDPhD, Diane Damotte, MDPhD, Didier Bouscary, MDPhD, Jerome Tamburini Bonnefoy, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1573.
https://doi.org/10.1182/blood.V130.Suppl_1.1573.1573
Published: 2017
Journal Articles

Prognostic Value of Early 18F-FDG PET/CT Scanner Evaluation in Immunocompetent Primary CNS Lymphoma Patients

Rudy Birsen, Estelle Blanc, MD, Barbara Burroni, MD, Chloe Broudin, MD, Lise Willems, MD, Marielle Legoff, MD, Emmanuelle Leray, MD, Sylvain Pilorge, MD, Sawsen Salah, MD, Aude Quentin, MD, Bénédicte Deau-Fisher, MD, Patricia Franchi, MD, Marguerite Vignon, MD, Laurence Mabille, MD, Charles Nguyen, MD, Youlia Kirova, MD, Pascale Varlet, MD, Arnault tauziede-Espariat, MD, Myriam Edjlali, MD, Dezamis Edouard, MD, Khe Hoang-xuan, MD PhD, Caroline Houillier, MD, Carole Soussain, MD PhD, Johan Pallud, MDPhD, Diane Damotte, MDPhD, Didier Bouscary, MDPhD, Jerome Tamburini Bonnefoy, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4169.
https://doi.org/10.1182/blood.V130.Suppl_1.4169.4169
Published: 2017