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Journal Articles

Elenestinib, an Investigational, Next Generation KIT D816V Inhibitor, Reduces Mast Cell Burden, Improves Symptoms, and Has a Favorable Safety Profile in Patients with Indolent Systemic Mastocytosis: Analysis of the Harbor Trial

Tsewang Tashi, Olivier Hermine, Mariana Castells, Mar Guilarte, Vito Sabato, Marcus Maurer, Jens Panse, Ivan Alvarez-Twose, Renata Cabral, Robert Bird, Stéphane Barete, Laurence Bouillet, Maud Hermans, Paul Van Daele, David González-De-Olano, Elizabeth A. Griffiths, Joseph Jurcic, Ingunn Dybedal, Gandhi Laurent Damaj, Philippe Schafhausen, Chiara Elena, Tse-Chieh Teh, Pankit Vachhani, Caroline Labe, Saranya Venugopal, Kevin He, Javier Muñoz-González, Ben Lampson, Robyn Scherber, Prithviraj Bose, Clive Grattan, Thanai Pongdee, Tracy I. George, Cristina Bulai Livideanu
Journal: Blood
Blood (2023) 142 (Supplement 1): 76.
https://doi.org/10.1182/blood-2023-188904
Published: 2023
Journal Articles

Combination Chemotherapy in Patients with Newly Diagnosed Blastic Plasmacytoid Dendritic Cell Neoplasms (BPDCN): First Results of a Prospective French Trial (LpDessai)

Eric Deconinck, Berengere Gruson, Sabeha Biichle, Anne Roggy, Florian Renosi, Thomas Fournet, Maxime Desmarets, Gregory Tio, Tony Marchand, Mikael Roussel, Thibaut Leguay, Jean-Philippe Vial, Francoise Huguet, Francois Vergez, Emilie Chalayer, Khaoula Mahfoudi, Fressia Honeyman, Sebastien Maury, Nicolas Freynet, Caroline Bonmati, Veronique Latger-Cannard, Eve Gehlkopf, Caroline Bret, Damien Roos Weil, Magali Le Garff-Tavernier, Sophie Rigaudeau, Gandhi Laurent Damaj, Edouard Cornet, Remy Gressin, Marie-Christine Jacob, Delphine Martineau, Aguirre Mimoun, Alice Garnier, Marion Eveillard, Alban Villate, Emmanuelle Rault, Fanny Delettre, Francine Garnache Ottou
Journal: Blood
Blood (2023) 142 (Supplement 1): 1516.
https://doi.org/10.1182/blood-2023-173379
Published: 2023
Journal Articles

Induction and Maintenance Therapy in Elderly Patients with Mantle Cell Lymphoma: Double-Randomized MCL R2 Elderly Clinical Trial By the European Mantle Cell Lymphoma Network

Vincent Ribrag, Violaine Safar, Hanneke Kluin-Nelemans, Lucie Oberic, Pierre Feugier, Olivier Casasnovas, Catherine Thieblemont, Nicolas Daguindau, Gandhi Laurent Damaj, Eva Hoster, Ludwig Fischer von Weikersthal, Mathias Hänel, Marc Andre, Maria Gomes Da Silva, Ana Marín Niebla, Michal Taszner, Jan Walewski, Rinske Boersma, Marie-Helene Delfau-Larue, Steven Le Gouill, Martin Dreyling
Journal: Blood
Blood (2023) 142 (Supplement 1): 979.
https://doi.org/10.1182/blood-2023-188788
Published: 2023
Journal Articles

Obinutuzumab Versus Rituximab in Transplant Eligible Untreated MCL Patients, a Matching Comparison between the Lyma and Lyma-101 Trials

Clementine Sarkozy, Mary Callanan, Catherine Thieblemont, Lucie Oberic, Barbara Burroni, Krimo Bouabdallah, Gandhi Laurent Damaj, Benoit Tessoulin, Vincent Ribrag, Roch Houot, Franck Morschhauser, Victoria Cacheux, Vincent Delwail, Violaine Safar, Remy Gressin, Morgane Cheminant, Olivier Hermine, Elizabeth A. Macintyre, Steven Le Gouill
Journal: Blood
Blood (2023) 142 (Supplement 1): 980.
https://doi.org/10.1182/blood-2023-174416
Published: 2023
Journal Articles

Prognostic Characterization of Advanced Mastocytosis Patients Treated with Midostaurin According to Diagnosis and Mutation-Adjusted Risk Score: A Nation-Wide Ceremast Study of 170 Patients

Mael Heiblig, Clement Gourguechon, Philippe Guilpain, Cristina Bulai Livideanu, Stéphane Barete, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Gandhi Laurent Damaj, Thomas Ballul, Céline Greco, Laura Polivka, Laurent Frenzel, Cecile Meni, Hassiba Bouktit, Caroline Gaudy-Marqueste, Marie Gousseff, Edwige Le Mouel, Antoine Neel, Dana Ranta, Roland Jaussaud, Thierry Jo Molina, Julie Bruneau, Ludovic Lhermitte, Marie Temple, Olivier Kosmider, Rose-Marie Javier, Fabien Pelletier, Florence Castelain, Frédérique Retornaz, Quentin Cabrera, Patricia Zunic, Marie-Pierre Gourin, Ewa Wierzbicka-Hainaut, Jean-Francois Viallard, Christian Lavigne, Cyrille Hoarau, Isabelle Durieu, Sophie Dimicoli-Salazar, Jose-Miguel Torregrosa-Diaz, Angele Soria, Michel Arock, Christine Bodemer, Olivier Lortholary, Olivier Hermine, Julien Rossignol
Journal: Blood
Blood (2023) 142 (Supplement 1): 1837.
https://doi.org/10.1182/blood-2023-185890
Published: 2023
Journal Articles

Interleukin 10 (IL10) and IL15 Significantly Decreased in Chronic Myeloid Leukemia Patients Presenting with Tyrosine Kinase Inhibitor (TKI) Withdrawal Syndrome (TWS). Results from the Prospective, Explorative and Multicenter « Kiwis » Study Designed for TWS. Clinicaltrial.Gov ID: NCT03996096; Study Number: 18-206

Hyacinthe A. Johnson-Ansah, Anaïs Briant, Amandine Charbonnier, Nathalie Cambier, Gandhi Laurent Damaj, Pascal Lenain, Alexandra Henry, Jean-Jacques Parienti, David Guenet, Anne-Claire GAC Besnard, Baptiste Delapierre, Franck E. Nicolini, Brigitte Le Mauff, Marc G. Berger
Journal: Blood
Blood (2023) 142 (Supplement 1): 6335.
https://doi.org/10.1182/blood-2023-177651
Published: 2023
Journal Articles

Trial in Progress: Outcomes in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma Treated with Systemic Therapy from Real-World Experience (ORCHID)

Catherine Thieblemont, Qiufei Ma, Christian Hampp, James Harnett, Rachel E. Sobel, Jessica J. Jalbert, Ruben G.W. Quek, Wenhui Wei, Ning Wu, Vera Mastey, Joy Wang, Anit Bajwa, Benedikt Maissenhaelter, Chantal van Gils, Shivani Aggarwal, Aafia Chaudhry, Hesham Mohamed, Srikanth R. Ambati, Emmanuel Bachy, Gandhi Laurent Damaj
Journal: Blood
Blood (2022) 140 (Supplement 1): 8065–8067.
https://doi.org/10.1182/blood-2022-158418
Published: 2022
Journal Articles

Trial in Progress: Follicular Lymphoma Outcomes in Relapsed/Refractory Patients Treated with Systemic Therapy in a Real-World Assessment (FLORA)

Emmanuel Bachy, Gandhi Laurent Damaj, Qiufei Ma, Christian Hampp, James Harnett, Rachel E. Sobel, Jessica J. Jalbert, Ruben G.W. Quek, Wenhui Wei, Ning Wu, Vera Mastey, Joy Wang, Anit Bajwa, Benedikt Maissenhaelter, Chantal van Gils, Shivani Aggarwal, Aafia Chaudhry, Hesham Mohamed, Srikanth R. Ambati, Catherine Thieblemont
Journal: Blood
Blood (2022) 140 (Supplement 1): 5198–5200.
https://doi.org/10.1182/blood-2022-158419
Published: 2022
Journal Articles

The ALK-OBS Trial: Results of a Multicenter Prospective Study Assessing the Prognostic Value of New Markers in Adults with ALK-Positive ALCL Treated By CHOEP: A Lysa Study

David Sibon, Laurence Lamant, Véronique Vergé, Loic Ysebaert, Catherine Thieblemont, Krimo Bouabdallah, Jehan Dupuis, Rémy Gressin, Emmanuel Bachy, Yann Guillermin, Nicolas Daguindau, Charlotte Syrykh, Choquet Sylvain, Pierre Feugier, Caroline Delette, Olivier Casasnovas, Marlene Ochmann, Ronan Le Calloch, Emmanuel Gyan, Herve Tilly, Gandhi Laurent Damaj, Olivier Tournilhac
Journal: Blood
Blood (2022) 140 (Supplement 1): 3680–3682.
https://doi.org/10.1182/blood-2022-170841
Published: 2022
Journal Articles

Addition of Brentuximab Vedotin to Gemcitabine in Relapsed or Refractory T-Cell Lymphoma: Final Analysis of a Lysa Multicenter, Phase II Study. "the TOTAL Trial"

Olivier Tournilhac, Solene Lecolant, Maya Hacini, Krimo Bouabdallah, Sebastien Bailly, Kamel Laribi, Thibaut Belmondo, Marie Maerevoet, Loic Ysebaert, Stéphanie Guidez, Steven Le Gouill, Christophe Bonnet, Marc Andre, Jehan Dupuis, Catherine Thieblemont, Emmanuel Bachy, Nicolas Daguindau, Franck Morschhauser, Sabine Tricot, Pierre Feugier, Anne Banos, Thierry Lamy, Adrien Chauchet, Emmanuel Gyan, Guillaume Cartron, Hassan Farhat, Vincent Camus, Bernard Drenou, Hacene Zerazhi, David Sibon, Emmanuelle Nicolas-Virelizier, Caroline Delette, Sylvia Snauwaert, Nicole Straetmans, Richard Delarue, Marie Parrens, Samuel Griolet, Philippe Gaulard, Marie-Helene Delfau-Larue, Laurence De Leval, Gandhi Laurent Damaj
Journal: Blood
Blood (2022) 140 (Supplement 1): 2302–2305.
https://doi.org/10.1182/blood-2022-165217
Published: 2022
Journal Articles

Rituximab-Lenalidomide(R2) Maintenance Is Superior to Rituximab Maintenance after First Line Immunochemotherapy in Mantle Cell Lymphoma: Results of the MCL R2 Elderly Clinical Trial

Vincent Ribrag, Violaine Safar, Hanneke Kluin-Nelemans, Lucie Oberic, Pierre Feugier, Olivier Casasnovas, Catherine Thieblemont, Nicolas Daguindau, Gandhi Laurent Damaj, Wolfram Klapper, Eva Hoster, Ludwig Fischer von Weikersthal, Mathias Haenel, Marc André, Maria Gomes da Silva, Fernando Carcinero, Ana Marin-Niebla, Michal Taszner, Jan Walewski, Rinske Boersma, Ilse Houtenbos, Marie-Helene Delfau-Larue, Steven Le Gouill, Martin H. Dreyling
Journal: Blood
Blood (2021) 138 (Supplement 1): 379.
https://doi.org/10.1182/blood-2021-149600
Published: 2021
Journal Articles

Salvage Therapy with Brentuximab-Vedotin and Bendamustine for Patients with Relapsed/Refractory T Cell Lymphoma. a Multicenter and Retrospective Study

Krimo Bouabdallah, Raphaëlle Aubrais, Loïc Chartier, Charles Herbaux, Anne Banos, Pauline Brice, Marlene Ochmann, David Sibon, Jean Marc Schiano De Colella, Thomas Cluzeau, Kamel Laribi, Ronan Le Calloch, Mathieu Bellal, Nicolas Daguindau, Sandy Amorim, Kossi Agbetiafa, Adrien Chauchet, Marwa Hammami, Eric Durot, Christophe Bonnet, Margot Robles, Ludovic Fouillet, Fontanet Bijou, Olivier Tournilhac, Philippe Gaulard, Marie Parrens, Noel-Jean Milpied, Gandhi Laurent Damaj
Journal: Blood
Blood (2021) 138 (Supplement 1): 620.
https://doi.org/10.1182/blood-2021-150953
Published: 2021
Journal Articles

Radiotherapy (WBRT) or Autologous Stem-Cell Transplantation (ASCT) for Primary CNS Lymphoma in Patients 60 Years of Age and Younger: Long-Term Results of the Intergroup Anocef-Goelams Randomized Phase II Precis Study

Caroline Houillier, Luc Taillandier, Roch Houot, Olivier Chinot, Cecile Molucon-Chabrot, Anna Schmitt, Rémy Gressin, Choquet Sylvain, Gandhi Laurent Damaj, Julie Abraham, Vincent Delwail, Emmanuel Gyan, Sylvain Dureau, Laurence Sanhes, Jérôme Cornillon, Reda Garidi, Alain Delmer, Marie-laure Tanguy, Ahmad Kanj AL Jijakli, Pierre Morel, Marie-Pierre Moles, Adrien Chauchet, Thomas Gastinne, Loïc Feuvret, Nathalie Cassoux, Valerie Touitou, Damien Ricard, Frédéric Peyrade, Mouna Laadhari, Anne-Sophie Plissonnier, Khe Hoang-Xuan, Carole Soussain
Journal: Blood
Blood (2021) 138 (Supplement 1): 658.
https://doi.org/10.1182/blood-2021-146389
Published: 2021
Journal Articles

Final Analysis of a Prospective Multicenter Phase II Trial of the Lymphoma Study Association (LYSA) Using Prednisone, Vinblastine, Doxorubicin and Bendamustine (PVAB) Regimen in First Line Therapy for Patients over 60 Years with Advanced-Stage Classical Hodgkin Lymphoma

Herve Ghesquieres, Rene-Olivier Casasnovas, Emmanuelle Nicolas-Virelizier, Salim Kanoun, Gandhi Laurent Damaj, Vincent Delwail, Arnaud Jaccard, Kamel Laribi, Franck Morschhauser, Christophe Bonnet, Agathe Waultier, Frederique Orsini-Piocelle, Marc Andre, Marguerite Fournier, Fabienne Morand, Alina Berriolo-Riedinger, Diane Damotte, Alexandra Traverse-Glehen, Philippe Quittet, Pauline Brice
Journal: Blood
Blood (2021) 138 (Supplement 1): 1370.
https://doi.org/10.1182/blood-2021-152346
Published: 2021
Journal Articles

Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells

Clinical Trials & Observations
Cédric Pastoret, Fabienne Desmots, Gaëlle Drillet, Simon Le Gallou, Marie-Laure Boulland, Alexia Thannberger, Anne-Violaine Doncker, Véronique Salaun, Gandhi Laurent Damaj, Richard Veyrat-Masson, Olivier Tournilhac, Aline Moignet, Céline Pangault, Mikaël Roussel, Thierry Fest, Thierry Lamy
Journal: Blood
Blood (2021) 137 (23): 3237–3250.
https://doi.org/10.1182/blood.2020006721
Published: 2021
Includes: Supplemental data
Journal Articles

Final Analysis of the Ro-CHOP Phase III Study (Conducted by LYSA): Romidepsin Plus CHOP in Patients with Peripheral T-Cell Lymphoma

Emmanuel Bachy, MD PhD, Vincent Camus, Catherine Thieblemont, MD PhD, Rene-Olivier Casasnovas, MD, Loic Ysebaert, MD PhD, Gandhi Laurent Damaj, MD PhD, Stephanie Guidez, Gian-Matteo Pica, MD, Won Seog Kim, MD PhD, Soon Thye Lim, MBBS, MRCP, FAMS, Marc André, MD, Alejandro Martin Garcia-Sancho, MD PhD, Maria Jesus Penarrubia Ponce, MD, Philipp B. Staber, MD PhD, Judith Trotman, FRACP, Andreas Hüttmann, MD, Vittorio Stefoni, MD PhD, Alessandro Re, MD, Philippe Gaulard, MD PhD, Marie-Helene Delfau-Larue, MD PhD, Laurence De Leval, MD, Michel Meignan, MD, Ju Li, PhD, Franck Morschhauser, MD PhD, Richard Delarue, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-134440
Published: 2020
Journal Articles

Addition of Brentuximab Vedotin to Gemcitabine in Relapsed or Refractory T-Cell Lymphoma: Results of a Lysa Multicenter, Phase II Study. "the TOTAL Trial"

Olivier Tournilhac, MD PhD, Maya Hacini, MD, Kamal Bouabdallah, MD, Kamel Laribi, MD, Marie Maerevoet, MD, Loic Ysebaert, MD PhD, Stephanie Guidez, Steven Le Gouill, MD PhD, Marc André, MD, Jehan Dupuis, MD, Catherine Thieblemont, MD PhD, Emmanuel Bachy, MD PhD, Nicolas Daguindau, MD, Franck Morschhauser, MD PhD, Sabine Tricot, MD, Pierre Feugier, MD PhD, Anne Banos, MD, Thierry Lamy De La Chapelle, MD PhD, Adrien Chauchet, MD, Emmanuel Gyan, MD PhD, Guillaume Cartron, MD PhD, Hassan Farhat, MD, Vincent Camus, Bernard Drenou, MD PhD, Hacene Zerazhi, MD, David Sibon, MD PhD, Emmanuelle Nicolas-Virelizier, MD, Caroline Delette, MD, Sylvia Snauwaert, MD, Nicole Straetmans, MD, Richard Delarue, MD, Marie Parrens, MD, Céline Bossard, MD, Laurence De Leval, MD, Philippe Gaulard, MD PhD, Gandhi Laurent Damaj, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-139224
Published: 2020
Journal Articles

First Results of the Acsé Pembrolizumab Phase II in the Primary CNS Lymphoma (PCNSL) Cohort

Khe Hoang-Xuan, MDPhD, Roch Houot, MDPhD, Carole Soussain, MD PhD, Marie Blonski, MD, Anna Schmitt, MD, Vincent Delwail, MD, Gandhi Laurent Damaj, MD PhD, Herve Ghesquieres, MD PhD, Frédéric Peyrade, MD, Adrian Tempescul, MD, Julie Abraham, MD, Philippe Agape, MD, Guido Ahle, MD, Nathalie Baize, MD, Pierre Bories, MD, Chantal Campello, MD, Emmanuel Gyan, MD PhD, Fabrice Jardin, MD PhD, Philippe Rey, MD, Sylvain Choquet, MD, Caroline Houillier, MD, Nathalie Cassoux, MDPhD, Valerie Touitou, MDPhD, Nadine Martin-Duverneuil, MD, Frederic Legrand, Assia Lamrani-Ghaouti, Ophelie Querel, Natalie Hoog Labouret, MD, Clotilde Simon, Sylvie Chevret, MDPhD, Christophe Massard, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-141773
Published: 2020
Journal Articles

Final Analysis of the International Double-Blind Randomized Phase III Study of Lenalidomide Maintenance in Elderly Patients with DLBCL in Response after R-CHOP, the Remarc Study from Lysa

Catherine Thieblemont, MD PhD, Maria Gomes da Silva, MD, Olivier Casasnovas, MD, Hervé Ghesquieres, MD PhD, Gandhi Laurent Damaj, MD PhD, Judith Trotman, FRACP, Pierre Feugier, MD PhD, Corinne Haioun, MDPhD, Richard Greil, MD, Dolores Caballero, MD PhD, Armando Lopez-Guillermo, Sebastian Grosicki, MD PhD, Koen Van Eygen, MD, Sylvia Snauwaert, MD, Ewa Lech-Marańda, MD PhD, Sonja Heibl, MD, John Catalano, MBBS, FRACP, FRCPA, Amos Cohen, MD, Anne Cairoli, MD, Philippe Gaulard, MD PhD, Franck Morschhauser, MD PhD, Herve Tilly, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-136511
Published: 2020
Journal Articles

Acalabrutinib Monotherapy in Patients with Relapsed/Refractory Mantle Cell Lymphoma: Long-Term Efficacy and Safety Results from a Phase 2 Study

Michael Wang, MD, Simon Rule, MD PhD, Pier Luigi Zinzani, MD, Andre H. Goy, MD, Rene-Olivier Casasnovas, MD, Stephen D. Smith, MD, Gandhi Laurent Damaj, MD PhD, Jeanette K. Doorduijn, MD PhD, Thierry Lamy, Franck Morschhauser, MD PhD, Carlos Panizo, MD PhD, Bijal Shah, MD, Andrew Davies, MD PhD, Richard Eek, FRACP., Jehan Dupuis, MD, Eric Jacobsen, MD, Arnon P. Kater, MDPhD, Steven Le Gouill, MD PhD, Lucie Oberic, MD, Tadeusz Robak, MDPhD, Preetesh Jain, MBBS,MDDM,PhD, Graham Brock, PhD, Priti Patel, MD, Lin Tao, Monika Dlugosz-Danecka, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-134824
Published: 2020