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Caroline Houillier
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Journal Articles

CAR T-cell therapy in secondary CNS lymphomas: A real-world study from the descar-t registry

Free
Caroline Houillier, Elena Robin-Marieton, Cécile Pizot, Roch Houot, Fabien Le Bras, Aline Schmidt, François-Xavier Gros, Catherine Thieblemont, Guillaume Cartron, Thomas Gastinne, Cristina Castilla-Llorente, Justine Decroocq, Blandine Guffroy, Ibrahim Yakoub-Agha, Emmanuel Gyan, Julie Abraham, Olivier Hermine, Adrien Chauchet, Amandine Durand, Marie-Thérèse Rubio, Jacques-Olivier Bay, Emmanuel Bachy, Steven Le Gouill, Khe Hoang-Xuan, Carole Soussain, Hélène Tonoli, Luc-Matthieu Fornecker, Choquet Sylvain
Journal: Blood
Blood (2025) 146 (Supplement 1): 1012.
https://doi.org/10.1182/blood-2025-1012
Published: 2025
Journal Articles

Safety and efficacy of CD3xCD20 bispecific antibody for the treatment of primary and secondary central nervous system lymphoma patients: A multicentric retrospective study

Free
Adrien Gilbert, Inès Boussen, Hippolyte Bardet, Sandy Amorim, Florence Lachenal, François Lemonnier, Guillaume Dachy, Sarah Bailly, Marie Blonski, Steeve Chevreux, Adrien Chauchet, Clemence Loiseau, Valerie Vidal, Jean-Baptiste Bossard, Caterina Cristinelli, Driss Chaoui, Julie Abraham, Sophie Bernard, Herve Ghesquieres, Morgane Nudel Ortmans, Lise Willems, Celia Salanoubat, Caroline Houillier, Choquet Sylvain, Baptiste Delapierre, Carole Soussain
Journal: Blood
Blood (2025) 146 (Supplement 1): 1018.
https://doi.org/10.1182/blood-2025-1018
Published: 2025
Journal Articles

Results of the primary end-point of the LOC-R01: A randomized phase II Study of lenalidomide and ibrutinib in association with rituximab-methotrexate procarbazine vincristin (R-MPV) as a targeted induction treatment for patients aged 18 to 65 with a newly diagnosed primary central nervous system lymphoma (PCNSL)

Free
Carole Soussain, Caroline Houillier, Marion Chevrier, Delphine Leclercq, Joya El Haddad, Anna Schmitt, Lucie Oberic, Cécile Moluçon-Chabrot, Julie Abraham, Fabrice Jardin, Gandhi Damaj, Laurence Schenone, Jérôme Paillassa, Agathe Waultier-Rascalou, Kossi Agbetiafa, Remy Gressin, Choquet Sylvain, Thomas Gastinne, Luc Taillandier, Luc-Matthieu Fornecker, Lise Willems, Adrien Chauchet, Guido Ahle, Gabriel Antherieu, Adrien Gilbert, Khe Hoang-Xuan, Olivier Lantz, Chaimae Saji, Ana Lalanne, Herve Ghesquieres
Journal: Blood
Blood (2025) 146 (Supplement 1): 58.
https://doi.org/10.1182/blood-2025-58
Published: 2025
Journal Articles

First results of the methoglu Trial, a phase 1 Trial from the LOC network evaluating the reduction of the time interval between methotrexate perfusions combined with glucarpidase in relapsed primary CNS lymphomas

Free
Caroline Houillier, Lisa Belin, Cécile Moluçon-Chabrot, Noël Zahr, Angel Escamilla, Carole Soussain, Lise Willems, Choquet Sylvain, Renata Ursu, Marie Blonski, Ariane Mbekwe Yepnang, Sirine Mersali, Laura Rozenblum, Valérie Touitou, Magali Le Garff-Tavernier, Lucia Nichelli, Yah-se Abada, Assitan Kone-Haidara, Alice Laurenge, Khe Hoang-Xuan
Journal: Blood
Blood (2025) 146 (Supplement 1): 1904.
https://doi.org/10.1182/blood-2025-1904
Published: 2025
Journal Articles

Highly Sensitive Interleukin Score for Intra-Ocular Lymphoma Diagnosis: Evidence from Analysis of 5-Year Real-Life of Use

Free
Elise Sourdeau, Martin Chevalier, Hélène Masse, Julie Gueudry, Yann Maucourant, Marie-Laure Le Lez, Philippe Gohier, Marie Alice Laville, Nathalie Cassoux, Fatma Abid Mzid, Mohamed Ali Gargouri, Marie Marechal, Guido Ahle, Clotilde Devin, Sara Touhami, Valerie Touitou, Caroline Houillier, Khe Hoang-Xuan, Choquet Sylvain, Carole Soussain, Adélaïde Toutee, Magali Le Garff-Tavernier
Journal: Blood
Blood (2023) 142 (Supplement 1): 3002.
https://doi.org/10.1182/blood-2023-182192
Published: 2023
Journal Articles

Efficacy of CAR-T Cells in Primary Central Nervous System Lymphomas: The French Experience of the National LOC Network

Free
Choquet Sylvain, Magali Le Garff-Tavernier, Laetitia Souchet, Damien Roos Weil, Veronique Morel, Madalina Uzunov, Carole Metz, Stephanie Nguyen Quoc, Nathalie Jacque, Nicolas Gauthier, Lise Willems, Agathe Waultier, Celia Salanoubat, Roch Houot, Renata Ursu, Maryline Barrie, Guido Ahle, Carole Soussain, Marion Alcantara, Caroline Houillier
Journal: Blood
Blood (2022) 140 (Supplement 1): 7540–7541.
https://doi.org/10.1182/blood-2022-167784
Published: 2022
Journal Articles

CAR T-cell therapy in primary central nervous system lymphoma: the clinical experience of the French LOC network

Free
Clinical Trials & Observations
Marion Alcantara, Caroline Houillier, Marie Blonski, Marie-Thérèse Rubio, Lise Willems, Agathe Waultier Rascalou, Magali Le Garff-Tavernier, Karim Maloum, Clotilde Bravetti, Laetitia Souchet, Damien Roos-Weil, Véronique Morel, Madalina Uzunov, Carole Metz, Meriem Dhib-Charfi, Stéphanie Nguyen, Natalia Shor, Dimitri Psimaras, Nicolas Weiss, Nathalie Jacque, Silvia Solorzano, Nicolas Gauthier, Marie Le Cann, Françoise Norol, Carole Soussain, Sylvain Choquet
Journal: Blood
Blood (2022) 139 (5): 792–796.
https://doi.org/10.1182/blood.2021012932
Published: 2022
Includes: Supplemental data
Journal Articles

Radiotherapy (WBRT) or Autologous Stem-Cell Transplantation (ASCT) for Primary CNS Lymphoma in Patients 60 Years of Age and Younger: Long-Term Results of the Intergroup Anocef-Goelams Randomized Phase II Precis Study

Free
Caroline Houillier, Luc Taillandier, Roch Houot, Olivier Chinot, Cecile Molucon-Chabrot, Anna Schmitt, Rémy Gressin, Choquet Sylvain, Gandhi Laurent Damaj, Julie Abraham, Vincent Delwail, Emmanuel Gyan, Sylvain Dureau, Laurence Sanhes, Jérôme Cornillon, Reda Garidi, Alain Delmer, Marie-laure Tanguy, Ahmad Kanj AL Jijakli, Pierre Morel, Marie-Pierre Moles, Adrien Chauchet, Thomas Gastinne, Loïc Feuvret, Nathalie Cassoux, Valerie Touitou, Damien Ricard, Frédéric Peyrade, Mouna Laadhari, Anne-Sophie Plissonnier, Khe Hoang-Xuan, Carole Soussain
Journal: Blood
Blood (2021) 138 (Supplement 1): 658.
https://doi.org/10.1182/blood-2021-146389
Published: 2021
Journal Articles

First Results of the Acsé Pembrolizumab Phase II in the Primary CNS Lymphoma (PCNSL) Cohort

Free
Khe Hoang-Xuan, MDPhD, Roch Houot, MDPhD, Carole Soussain, MD PhD, Marie Blonski, MD, Anna Schmitt, MD, Vincent Delwail, MD, Gandhi Laurent Damaj, MD PhD, Herve Ghesquieres, MD PhD, Frédéric Peyrade, MD, Adrian Tempescul, MD, Julie Abraham, MD, Philippe Agape, MD, Guido Ahle, MD, Nathalie Baize, MD, Pierre Bories, MD, Chantal Campello, MD, Emmanuel Gyan, MD PhD, Fabrice Jardin, MD PhD, Philippe Rey, MD, Sylvain Choquet, MD, Caroline Houillier, MD, Nathalie Cassoux, MDPhD, Valerie Touitou, MDPhD, Nadine Martin-Duverneuil, MD, Frederic Legrand, Assia Lamrani-Ghaouti, Ophelie Querel, Natalie Hoog Labouret, MD, Clotilde Simon, Sylvie Chevret, MDPhD, Christophe Massard, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
https://doi.org/10.1182/blood-2020-141773
Published: 2020
Journal Articles

Temozolomide is effective and well tolerated in patients with primary vitreoretinal lymphoma

Free
Clinical Trials & Observations
Marine Baron, Lisa Belin, Nathalie Cassoux, Christine Fardeau, Marion Blaizeau, Carole Soussain, Caroline Houillier, Khê Hoang-Xuan, Emmanuel Gyan, Marie-Laure Le Lez, Anne Lavaud, Pierre Soubeyran, Bahram Bodaghi, Myrto Costopoulos, Véronique Leblond, Valérie Touitou, Karim Maloum, Marie-Hélène Errera, Damien Roos-Weil, Magali Le Garff-Tavernier, Sylvain Choquet
Journal: Blood
Blood (2020) 135 (20): 1811–1815.
https://doi.org/10.1182/blood.2019003073
Published: 2020
Journal Articles

Primary Diffuse Large B-Cell CNS Lymphoma over 80 Years: An Analysis of 110 Patients from the French Oculo-Cerebral Lymphoma (LOC) Network

Free
Alizee Maarek, MD, Delphine Maucort-Boulch, MD PhD, Caroline Houillier, MD, Olivier Chinot, MD PhD, Fontanet Bijou, MD, Luc Taillandier, MD PhD, Philippe Agape, MD, Roch Houot, MD PhD, Eileen Boyle, MD, Cecile Molucon-Chabrot, MD PhD, Philippe Rey, MD, Sylvain Choquet, MD, Jerome Tamburini Bonnefoy, MD PhD, Arnaud Jaccard, MD PhD, Guido Ahle, MD, Michel Fabbro, MD, Anne-Claire Gac, MD, Jean-Come Meniane, MD, Marie Francoise Le Coz, MD, Emmanuel Gyan, MD PhD, Khe Hoang-Xuan, MD PhD, Carole Soussain, MD PhD, Herv Ghesquieres
Journal: Blood
Blood (2018) 132 (Supplement 1): 4206.
https://doi.org/10.1182/blood-2018-99-117331
Published: 2018
Journal Articles

Keep an Eye on CXCL-13: A Promising Biomarker to Help IL-10 and IL-6 for the Diagnosis of Intraocular Lymphomas

Free
Chloe Friedrich, Myrto Costopoulos, PharmD, Gregory Lazarian, PharmD, Choquet Sylvain, Martine Brissard, Caroline Houillier, MD, Nathalie Cassoux, MD PhD, Carole Soussain, MD PhD, Veronique Leblond, Helene Merle-Beral, MD PhD, Valerie Touitou, MD PhD, Magali Le Garff-Tavernier
Journal: Blood
Blood (2017) 130 (Supplement 1): 2841.
https://doi.org/10.1182/blood.V130.Suppl_1.2841.2841
Published: 2017
Journal Articles

Temozolomide in Relapse/Refractory Primary Vitreo-Retinal Lymphoma (R/R PVRL): A New Effective, Well-Tolerated and Cheap Reference. Result of a Study on Behalf of the LOC Network

Free
Choquet Sylvain, Marine Baron, Anne Lavaud, Carole Soussain, MD PhD, Valerie Touitou, MD PhD, Christine Fardeau, Nathalie Cassoux, MD PhD, Magali Le Garff-Tavernier, Mirto Costopoulos, Caroline Houillier, MD, Karim Maloum, Véronique Leblond, Emmanuel Gyan, MDPhD, Pierre Soubeyran, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2845.
https://doi.org/10.1182/blood.V130.Suppl_1.2845.2845
Published: 2017
Journal Articles

Prognostic Value of Early 18F-FDG PET/CT Scanner Evaluation in Immunocompetent Primary CNS Lymphoma Patients

Free
Rudy Birsen, Estelle Blanc, MD, Barbara Burroni, MD, Chloe Broudin, MD, Lise Willems, MD, Marielle Legoff, MD, Emmanuelle Leray, MD, Sylvain Pilorge, MD, Sawsen Salah, MD, Aude Quentin, MD, Bénédicte Deau-Fisher, MD, Patricia Franchi, MD, Marguerite Vignon, MD, Laurence Mabille, MD, Charles Nguyen, MD, Youlia Kirova, MD, Pascale Varlet, MD, Arnault tauziede-Espariat, MD, Myriam Edjlali, MD, Dezamis Edouard, MD, Khe Hoang-xuan, MD PhD, Caroline Houillier, MD, Carole Soussain, MD PhD, Johan Pallud, MDPhD, Diane Damotte, MDPhD, Didier Bouscary, MDPhD, Jerome Tamburini Bonnefoy, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4169.
https://doi.org/10.1182/blood.V130.Suppl_1.4169.4169
Published: 2017
Journal Articles

Efficacy and Safety of Intensive Etoposide Aracytine Consolidation Following Rituximab Methotrexate Temozolomide Induction in Newly Diagnosed Primary Central Nervous System Lymphoma

Free
Rudy Birsen, Estelle Blanc, MD, Barbara Burroni, MD, Chloe Broudin, MD, Lise Willems, MD, Marielle Legoff, MD, Emmanuelle Leray, MD, Sylvain Pilorge, MD, Sawsen Salah, MD, Aude Quentin, MD, Bénédicte Deau-Fisher, MD, Patricia Franchi, MD, Marguerite Vignon, MD, Laurence Mabille, MD, Charles Nguyen, MD, Youlia Kirova, MD, Pascale Varlet, MD, Arnault tauziede-Espariat, MD, Myriam Edjlali, MD, Dezamis Edouard, MD, Carole Soussain, MD PhD, Caroline Houillier, MD, Johan Pallud, MDPhD, Diane Damotte, MDPhD, Didier Bouscary, MDPhD, Jerome Tamburini Bonnefoy, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1573.
https://doi.org/10.1182/blood.V130.Suppl_1.1573.1573
Published: 2017
Journal Articles

The French LOC Network for Primary CNS Lymphoma (PCNSL) Patients: What Can We Learn from a Large National Database?

Free
Carole Soussain, MD PhD, Caroline Houillier, MD, Herve Ghesquieres, MD PhD, Pierre Soubeyran, MD PhD, Olivier Chinot, MD PhD, Luc Taillandier, MD PhD, Roch Houot, MD PhD, Guido Ahle, MD, Emmanuel Gyan, MD PhD, Cécile Chabrot, MD, Marie-Pierre Moles, MD, Sylvain Choquet, MD, Philippe Agape, MD, Vincent Delwail, MD, Fabrice Jardin, MD PhD, Annie Brion, MD, Gandhi Damaj, MD, Olivier Casanovas, MD, Luc Mathieu Fornecker, MD PhD, Michel Fabbro, MD, Valerie Touitou, MD PhD, Nathalie Cassoux, MD PhD, Remy Gressin, MD, Adrian Tempescul, MD, Arnaud Jaccard, MD PhD, Pascal Bourquard, MD, Franck Morschhauser, Khê Hoang-Xuan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 926.
https://doi.org/10.1182/blood.V128.22.926.926
Published: 2016
Journal Articles

Whole Brain Radiotherapy (WBRT) Versus Intensive Chemotherapy with Haematopoietic Stem Cell Rescue (IC + HCR) for Primary Central Nervous System Lymphoma (PCNSL) in Young Patients: An Intergroup Anocef-Goelams Randomized Phase II Trial (PRECIS)

Free
Caroline Houillier, MD, Luc Taillandier, MD PhD, Thierry Lamy, MD PhD, Olivier Chinot, MD PhD, Cecile Molucon-Chabrot, MD, Pierre Soubeyran, MD PhD, Remy Gressin, MD, Sylvain Choquet, MD, Gandhi Damaj, MD, Antoine Thyss, MD, Arnaud Jaccard, MD PhD, Vincent Delwail, MD, Emmanuel Gyan, MD PhD, Laurence Sanhes, MD, Jerome Cornillon, MD, Reda Garidi, MD, Alain Delmer, MD PhD, Alexia Savignoni, MD, Ahmad AL Jijakli, MD, Pierre Morel, MD, Pascal Bourquard, MD, Marie-Pierre Moles, MD, Eric Deconinck, MD PhD, Pierre Morel, MD, Thomas Gastinne, MD, Jean-Marc Constans, MD, Adriana Langer, MD, Lucette Lacomblez, MD PhD, Daniel Delgadillo, Sylvain Dureau, Isabelle Turbiez, Anne-Sophie Plissonnier, Nathalie Cassoux, MD PhD, Valérie Touitou, MD PhD, Damien Ricard, MD PhD, Khê Hoang-Xuan, MD PhD, Carole Soussain, MD PhD
Journal: Blood
Blood (2016) 128 (22): 782.
https://doi.org/10.1182/blood.V128.22.782.782
Published: 2016
Journal Articles

Ibrutinib Monotherapy in Relapse or Refractory Primary CNS Lymphoma (PCNSL) and Primary Vitreo-Retinal Lymphoma (PVRL). Result of the Interim Analysis of the iLOC Phase II Study from the Lysa and the French LOC Network

Free
Sylvain Choquet, MD, Caroline Houillier, MD, Fontanet Bijou, MD, Roch Houot, MD PhD, Eileen Boyle, MD, Remy Gressin, MD, Emmanuelle Nicolas-Virelizier, MD, Maryline Barrie, MD, Cecile Molucon-Chabrot, MD, Marie Blonski, MD, Abderrazak El Yamani, MD, Marie-Laure LeLez, MD, Aline Clavert, MD, Solène Coisy, MD, Marjan Ertault de la Bretonnière, MD, Valérie Touitou, MD PhD, Nathalie Cassoux, MD PhD, Sami Boussetta, Florence Broussais, MD, Benedicte Gelas-Dore, Noélie Barzic, Herve Ghesquieres, MD PhD, Khê Hoang-Xuan, MD PhD, Carole Soussain, MD PhD
Journal: Blood
Blood (2016) 128 (22): 784.
https://doi.org/10.1182/blood.V128.22.784.784
Published: 2016
Journal Articles

Rituximab-Lenalidomide (REVRI) in Relapse or Refractory Primary Central Nervous System (PCNSL) or Vitreo Retinal Lymphoma (PVRL): Results of a "Proof of Concept" Phase II Study of the French LOC Network

Free
Herve Ghesquieres, MD PhD, Caroline Houillier, MD, Olivier Chinot, MD PhD, Sylvain Choquet, MD, Cecile Molucon-Chabrot, MD, Patrick Beauchene, MD, Remy Gressin, MD, Franck Morschhauser, Anna Schmitt, MD, Emmanuel Gyan, MD PhD, Khê Hoang-Xuan, MD PhD, Emmanuelle Nicolas-Virelizier, MD, Marion Chevrier, Alexia Savignoni, MD, Isabelle Turbiez, Florence Veillas, Vassili Soumelis, MD PhD, Carole Soussain, MD PhD
Journal: Blood
Blood (2016) 128 (22): 785.
https://doi.org/10.1182/blood.V128.22.785.785
Published: 2016
Journal Articles

Very High Efficiency of ICE (Ifosfamide-Carboplatin-Etoposide) in Relapse/Refractory (R/R) Primary Central Nervous System (PCNSL) and Vitreo-Retinal (VRL) Non Hodgkin Lymphoma. a LOC Network Multicenter Retrospective Study on 58 Cases

Free
Sylvain Choquet, MD, Adrien Grenier, MD, Caroline Houillier, MD, Carole Soussain, MD PhD, Marie Pierre Moles, MD, Thomas Gastinne, MD, Nathalie Cassoux, MD, Helene merle Beral, MD, Damien roos Weil, MD, Veronique Leblond, MD PhD, Khe hoang Xuan, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1524.
https://doi.org/10.1182/blood.V126.23.1524.1524
Published: 2015