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Christoph Rummelt
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Journal Articles

Plasmapheresis facilitates soluble BCMA clearance and contributes to reversing primary resistance to anti-BCMA immunotherapy in multiple myeloma

Free
Umair Munawar, Sven Neubert, Julia Mersi, Julia Norderer, Silvia Nerreter, Shilpa Kurian, Seungbin Han, Christina Verbruggen, Emma Besant, Nina Rein, Max Koeppel, Johanna Lehmann, Tabea Koehler, Hannah Labinsky, Sigrun Haeusl, Yoko Tamamushi, Xiang Zhou, Jule Pinter, Anna Laura Herzog, Kai Lopau, Elion Hoxha, Christoph Rummelt, Elena Gerhard-Hartmann, Andreas Rosenwald, Torsten Steinbrunn, Thomas Nerreter, Michael Hudecek, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Johannes Waldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 7465.
https://doi.org/10.1182/blood-2025-7465
Published: 2025
Journal Articles

Post allo-HCT menin-inhibition enhances graft-versus-leukemia effects by endogenous retrovirus induction in AML and T-cell activation

Free
Viktor Fetsch, Lennard Schwöbel, Ezgi Göknar, Anna-Verena Stell, Marco Punta, Thomas Plenge, Tabea Klaus, Manoj Gupta, Geoffroy Andrieux, Khalid Shoumariyeh, Sophie Pfeiffer, Eyleen Corrales, Lina Schlenke, Hosna Baniadam, Simon Brandl, Massimo Andreis, Michal Remen, Alina Hartmann, Kathleen Grueter, Melissa Zwick, Natalie Koehler, Monika Kuban, Eric Metzger, Christoph Rummelt, Justus Duyster, Melanie Boerries, Maike Hofmann, Julian Faerber, Lukas Braun, Alexander Zähringer, Michael Lübbert, Cristina Toffalori, Luca Vago, Florian Heidel, Susana Minguet, Petya Apostolova, Tobias Feuchtinger, Kristina Maas-Bauer, Franziska Blaeschke, Michael Kühn, H.Th. Marc Timmers, Tobias Wertheimer, Florian Perner, Robert Zeiser
Journal: Blood
Blood (2025) 146 (Supplement 1): 5862.
https://doi.org/10.1182/blood-2025-5862
Published: 2025
Journal Articles

Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AML

Available to Purchase
Viktor Fetsch, Lennard Frederik Schwöbel, Ezgi Ozyerli-Goknar, PhD, Anna-Verena Stell, Marco Punta, Thomas Plenge, Tabea Klaus, Manoj K. Gupta, Geoffroy Andrieux, Khalid Shoumariyeh, Sophie Pfeiffer, Eyleen Corrales, Lina Schlenke, Hosna Baniadam, Simon M. Brandl, Massimo Andreis, Michal Remen, Alina Hartmann, Kathleen Grueter, Melissa Zwick, Natalie Köhler, Monika Kuban, Eric Metzger, Christoph Rummelt, Justus Duyster, Melanie Börries, Maike Hofmann, Julian Färber, Lukas M Braun, Alexander Zähringer, Michael Lübbert, Cristina Toffalori, Luca Vago, Florian H Heidel, Susana Minguet, Petya Apostolova, Tobias Feuchtinger, Kristina Maas-Bauer, Franziska Blaeschke, Michael W.M. Kühn, Marc Timmers, Tobias Wertheimer, Florian Perner, Robert Zeiser
Journal: Blood
Blood blood.2025029712.
https://doi.org/10.1182/blood.2025029712
Published: 2025
Includes: Supplemental data
Journal Articles

Single-Center Experience of Decitabine/Venetoclax in Newly Diagnosed Older AML Patients with Non-Favorable Genetics: Bridging to Allo-HCT or Treatment Continuation

Free
David Alber, Christoph Rummelt, Tim Strüßmann, Andrés Rettig, Valeria Shlyakhto, Paul La Rosée, Martin Henkes, Elizaveta Bubnova, Tobias Ma, Johanna Thomas, Gabriele Ihorst, Claudia Wehr, Reinhard Marks, Heiko Becker, Justus Duyster, Ralph Wäsch, Jürgen Finke, Michael Lübbert
Journal: Blood
Blood (2023) 142 (Supplement 1): 7091.
https://doi.org/10.1182/blood-2023-187581
Published: 2023
Journal Articles

Decider-2: Prospective Randomized Multicenter Phase III Trial of Decitabine and Venetoclax Administered in Combination with All- Trans Retinoic Acid (ATRA) or Placebo in Patients with Acute Myeloid Leukemia Who Are Ineligible for Induction Chemotherapy

Free
Michael Lübbert, Claudia Schmoor, Olga Grishina, Christoph Rummelt, Johanna Thomas, Michael Heuser, Konstanze Döhner, Hartmut Döhner, Heiko Becker, Ralph Wäsch
Journal: Blood
Blood (2023) 142 (Supplement 1): 1495.
https://doi.org/10.1182/blood-2023-181871
Published: 2023
Journal Articles

Activity of Decitabine (DAC) Combined with All-Trans Retinoic Acid (ATRA) in Oligoblastic AML: Subgroup Analysis of a Randomized 2x2 Phase II Trial

Free
Michael Luebbert, MD PhD, Olga Grishina, Claudia Schmoor, Martina Crysandt, Edgar Jost, Felicitas Thol, Michael Heuser, Katharina S. Götze, Richard F. Schlenk, Konstanze Döhner, Helmut R. Salih, Marcus M. Schittenhelm, Gerhard Heil, Carsten Schwaenen, Carsten Mueller-Tidow, MD, Wolfram Brugger, Andrea Kündgen, Ulrich Germing, Maike de Wit, Stephan Kremers, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Professor Dr, Jürgen Krauter, Gesine Bug, Ralph Wäsch, Heiko Becker, Christoph Rummelt, Annette M. May, Justus Duyster, Arnold Ganser, Björn Hackanson, Hartmut Döhner
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-140664
Published: 2020
Journal Articles

Significance of the IL-3 Receptor Beta Chain (IL-3Rbc) for FLT3-ITD Dependent Oncogeneic Signaling in AML

Free
Christoph Rummelt, Sivahari Prasad Gorantla, PhD, Philip Keye, Kathrin Klaesener, Venkatesh Rao, Christian Peschel, MD, Michael Reth, Prof., PhD, Justus Duyster, MD PhD, Nikolas von Bubnoff, Prof., PhD
Journal: Blood
Blood (2015) 126 (23): 3660.
https://doi.org/10.1182/blood.V126.23.3660.3660
Published: 2015
Journal Articles

FLT3-ITD Interacts with and Phosphorylates IL-3β, and JAK1/2 Dependent IL-3β Activation Bypasses FLT3-ITD in FLT3 Kinase Independent Inhibitor Resistance in Vitro: Evidence for the Significance of IL-3β for FLT3-ITD Dependent Oncogeneic Signaling in AML.

Free
Christoph Rummelt, Sivahari P. Gorantla, Michael Sigl, Jana Saenger, Katharina Götze, Christian Peschel, MD, Justus Duyster, Nikolas von Bubnoff
Journal: Blood
Blood (2012) 120 (21): 2423.
https://doi.org/10.1182/blood.V120.21.2423.2423
Published: 2012