1-20 of 149
Helmut R. Salih
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Trial in Progress: Phase I Trial Evaluating an Immunopeptidome-Defined Multi-Peptide Vaccine Against Acute Myeloid Leukemia Stem and Progenitor Cells

Susanne Jung, Annika Nelde, Yacine Maringer, Monika Denk, Lisa Zieschang, Christine Kammer, Melek Özbek, Christopher Hackenbruch, Jonas S. Heitmann, Helmut R. Salih, Juliane S. Walz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1504.1.
https://doi.org/10.1182/blood-2024-198082
Published: 2024
Journal Articles

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study of Cln-049 for the Treatment of Acute Myeloid Leukemia Patients with Measurable Residual Disease

Jonas S. Heitmann, Juliane S. Walz, Helmut R. Salih, Klaus H Metzeler, Daniel Heudobler, Felicitas R Thol, Hermann Einsele, Veit L. Buecklein, Pau Montesinos, Ana Alfonso Pierola, Gala Vega, Eduardo Rodriguez Arboli, Juan Miguel Bergua Burgues, Suhail Chaudhry, Judith Inumerable, Todd Shearer, Laura Liu, Sandeep Kaur, Kaida Wu, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 2883.1.
https://doi.org/10.1182/blood-2024-201478
Published: 2024
Journal Articles

Perforin-Induced Killing in Leukemic Cells Is Driven By NFAT2-Mediated Cytoskeletal Remodeling

Samuel J. Holzmayer, Jonas Mauermann, Sarah M. Greiner, Jonas S. Heitmann, Kübra Kaban, Helmut R. Salih, Melanie Maerklin
Journal: Blood
Blood (2024) 144 (Supplement 1): 1406.
https://doi.org/10.1182/blood-2024-207673
Published: 2024
Journal Articles

Crosstalk between NFAT and NFκB Signaling Regulates NK Cell Immunosurveillance

Melanie Märklin, Samuel Holzmayer, Martin R. Mueller, Helmut R. Salih
Journal: Blood
Blood (2023) 142 (Supplement 1): 1183.
https://doi.org/10.1182/blood-2023-184446
Published: 2023
Journal Articles

Midostaurin Plus Intensive Chemotherapy for Younger and Older Patients with Acute Myeloid Leukemia and FLT3 Internal Tandem Duplications

Hartmut Döhner, Daniela Weber, Julia Krzykalla, Walter Fiedler, Gerald Wulf, Helmut R. Salih, Michael Lübbert, Michael W.M. Kühn, Thomas Schroeder, Hans Salwender, Katharina S. Götze, Jörg Westermann, Lars Fransecky, Karin Mayer, Bernd Hertenstein, Mark Ringhoffer, Hans-Joachim Tischler, Sigrid Machherndl-Spandl, Anika Schrade, Peter Paschka, Verena I Gaidzik, Frauke Theis, Felicitas R Thol, Michael Heuser, Richard F. Schlenk, Lars Bullinger, Maral Saadati, Axel Benner, Konstanze Döhner, Arnold Ganser
Journal: Blood
Blood (2021) 138 (Supplement 1): 692.
https://doi.org/10.1182/blood-2021-147256
Published: 2021
Journal Articles

Randomized Phase II Study of All- Trans Retinoic Acid and Valproic Acid Added to Decitabine in Newly Diagnosed Elderly AML Patients (DECIDER trial): Predictive Impact of TP53 Status

Heiko Becker, Claudia Schmoor, Olga Grishina, Dietmar Pfeifer, Dennis Zimmer, Martina Crysandt, Edgar Jost, Felicitas Thol, Michael Heuser, Katharina S. Goetze, Richard F. Schlenk, Helmut R. Salih, Marcus M. Schittenhelm, Gerhard Heil, Carsten Schwaenen, Carsten Müller-Tidow, Wolfram Brugger, Andrea Kündgen, Ulrich Germing, Maike de Wit, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Jürgen Krauter, Gesine Bug, Annette M. May, Ralph Wäsch, Justus Duyster, Konstanze Döhner, Arnold Ganser, Hartmut Döhner, Björn Hackanson, Michael Lübbert
Journal: Blood
Blood (2021) 138 (Supplement 1): 2380.
https://doi.org/10.1182/blood-2021-146468
Published: 2021
Journal Articles

Clonal evolution of acute myeloid leukemia with FLT3 -ITD mutation under treatment with midostaurin

Laura K. Schmalbrock, Anna Dolnik, Sibylle Cocciardi, Eric Sträng, Frauke Theis, Nikolaus Jahn, Ekaterina Panina, Tamara J. Blätte, Julia Herzig, Sabrina Skambraks, Frank G. Rücker, Verena I. Gaidzik, Peter Paschka, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Thomas Schroeder, Michael Lübbert, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Richard A. Larson, Arnold Ganser, Hendrik G. Stunnenberg, Saverio Minucci, Richard M. Stone, Clara D. Bloomfield, Hartmut Döhner, Konstanze Döhner, Lars Bullinger
Journal: Blood
Blood (2021) 137 (22): 3093–3104.
https://doi.org/10.1182/blood.2020007626
Published: 2021
Includes: Supplemental data
Journal Articles

Activity of Decitabine (DAC) Combined with All-Trans Retinoic Acid (ATRA) in Oligoblastic AML: Subgroup Analysis of a Randomized 2x2 Phase II Trial

Michael Luebbert, MD PhD, Olga Grishina, Claudia Schmoor, Martina Crysandt, Edgar Jost, Felicitas Thol, Michael Heuser, Katharina S. Götze, Richard F. Schlenk, Konstanze Döhner, Helmut R. Salih, Marcus M. Schittenhelm, Gerhard Heil, Carsten Schwaenen, Carsten Mueller-Tidow, MD, Wolfram Brugger, Andrea Kündgen, Ulrich Germing, Maike de Wit, Stephan Kremers, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Professor Dr, Jürgen Krauter, Gesine Bug, Ralph Wäsch, Heiko Becker, Christoph Rummelt, Annette M. May, Justus Duyster, Arnold Ganser, Björn Hackanson, Hartmut Döhner
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-140664
Published: 2020
Journal Articles

First-in-Human Phase I Dose Escalation and Expansion Study Evaluating the Fc Optimized FLT3 Antibody Flysyn in Acute Myeloid Leukemia Patients with Minimal Residual Disease

Jonas S. Heitmann, MD, Daniela Dörfel, MD, Sabine Kayser, MD, Michael Heuser, Felicitas Thol, Silke Kapp-Schwoerer, MD, Wolfgang Bethge, MD, Ludger Grosse-Hovest, Martin Steiner, Melanie Märklin, PhD, Juliane S. Walz, MD, Richard F. Schlenk, Gundram Jung, MD, Helmut R. Salih
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-139493
Published: 2020
Journal Articles

Next-Generation Sequencing (NGS)-Based Measurable Residual Disease (MRD) Monitoring in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication ( FLT3 -ITD + AML) Treated with Additional Midostaurin

Julia K. Herzig, PhD, Frank G. Rücker, MD, Laura K. Schmalbrock, MD, Tamara J. Blätte, PhD, Daniela Weber, MSc, Sabrina Skambraks, Silke Kapp-Schwoerer, MD, Andrea Corbacioglu, PhD, Verena I Gaidzik, MD, Peter Paschka, MD, Ekaterina Panina, MD, Nikolaus Jahn, MD, Anika Schrade, PhD, Frauke Theis, MD, Sibylle Cocciardi, PhD, Walter Fiedler, MD, Helmut R. Salih, Gerald Wulf, MD, Hans Salwender, MD, Thomas Schroeder, Katharina S. Götze, Thomas Kindler, MD, Michael Luebbert, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Lars Bullinger, MD, Konstanze Döhner
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-137568
Published: 2020
Journal Articles

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Sascha Geue, Katja Aurbach, Mailin-Christin Manke, Georgi Manukjan, Patrick Münzer, David Stegner, Caroline Brähler, Britta Walker-Allgaier, Melanie Märklin, Carla E. Borst, Leticia Quintanilla-Fend, Dominik Rath, Tobias Geisler, Helmut R. Salih, Peter Seizer, Florian Lang, Bernhard Nieswandt, Meinrad Gawaz, Harald Schulze, Irina Pleines, Oliver Borst
Journal: Blood
Blood (2019) 134 (21): 1847–1858.
https://doi.org/10.1182/blood.2019000185
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Interim Results of a First in Man Study with the Fc-Optimized FLT3 Antibody Flysyn for Treatment of Acute Myeloid Leukemia with Minimal Residual Disease

Sabine Kayser, MD, Jonas S. Heitmann, MD, Daniela Dörfel, MD, Felicitas Thol, MD, Michael Heuser, MD, Melanie Märklin, PhD, Carsten Müller-Tidow, MD, Martin Steiner, Ludger Grosse-Hovest, Gundram Jung, MD, Richard F. Schlenk, MD, Helmut R. Salih, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3928.
https://doi.org/10.1182/blood-2019-125327
Published: 2019
Journal Articles

Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3 -ITD

Clinical Trials & Observations
Richard F. Schlenk, Daniela Weber, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Hans Salwender, Thomas Schroeder, Thomas Kindler, Michael Lübbert, Dominik Wolf, Jörg Westermann, Doris Kraemer, Katharina S. Götze, Heinz-August Horst, Jürgen Krauter, Michael Girschikofsky, Mark Ringhoffer, Thomas Südhoff, Gerhard Held, Hans-Günter Derigs, Roland Schroers, Richard Greil, Martin Grießhammer, Elisabeth Lange, Alexander Burchardt, Uwe Martens, Bernd Hertenstein, Lore Marretta, Michael Heuser, Felicitas Thol, Verena I. Gaidzik, Wolfgang Herr, Julia Krzykalla, Axel Benner, Konstanze Döhner, Arnold Ganser, Peter Paschka, Hartmut Döhner
Journal: Blood
Blood (2019) 133 (8): 840–851.
https://doi.org/10.1182/blood-2018-08-869453
Published: 2019
Includes: Supplemental data
Journal Articles

The HLA ligandome landscape of chronic myeloid leukemia delineates novel T-cell epitopes for immunotherapy

Tatjana Bilich, Annika Nelde, Leon Bichmann, Malte Roerden, Helmut R. Salih, Daniel J. Kowalewski, Heiko Schuster, Chih-Chiang Tsou, Ana Marcu, Marian C. Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek, Tim H. Brümmendorf, Vladan Vucinic, Dietger Niederwieser, Jens Bauer, Melanie Märklin, Janet K. Peper, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanović, Juliane S. Walz
Journal: Blood
Blood (2019) 133 (6): 550–565.
https://doi.org/10.1182/blood-2018-07-866830
Published: 2019
Includes: Supplemental data
Journal Articles

In Vivo Kinetics of Early, Hypomethylating Agent-Induced Methylome and Transcriptome Changes in Primary AML Blasts: Random or Specific?

Gabriele Greve, Geoffroy Andrieux, Pascal Schlosser, Nadja Blagitko-Dorfs, Hans-Walter Lindemann, MD, Michael Heuser, MD, Andreas Neubauer, Jürgen Krauter, MD, Helmut R. Salih, MD, Gerhard Heil, Carsten Schwänen, Carsten Müller-Tidow, Arnold Ganser, MD, Hartmut Döhner, MD, Dietmar Pfeifer, Björn Hackanson, Olga Grishina, Melanie Boerries, Michael Lübbert
Journal: Blood
Blood (2018) 132 (Supplement 1): 3892.
https://doi.org/10.1182/blood-2018-99-118762
Published: 2018
Journal Articles

Mass Spectrometry-Based Immunopeptidome Analysis of Acute Myeloid Leukemia Cells Under Decitabine Treatment Delineates Induced Presentation of Cancer/Testis Antigens on HLA Class I Molecules

Jens Bauer, Nora Zieger, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 5223.
https://doi.org/10.1182/blood-2018-99-113357
Published: 2018
Journal Articles

Immunocytokines with Target Cell-Restricted IL-15 Activity for Induction of NK Cell Reactivity Against Acute Myeloid Leukemia (AML)

Bastian J. Schmied, MSc, Latifa Zekri, PhD, Martin Pflügler, PhD, Melanie Märklin, PhD, Lothar Kanz, Gundram Jung, Prof., MD, Helmut R. Salih, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 731.
https://doi.org/10.1182/blood-2018-99-112485
Published: 2018
Journal Articles

The HLA Ligandome Landscape of Chronic Myeloid Leukemia Delineates Novel T-Cell Epitopes for Immunotherapy

Tatjana Bilich, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Daniel Johannes Kowalewski, Heiko Schuster, Ana Marcu, Marian C. Neidert, Maren Lübke, Jonas Rieth, Mirle Schemionek, Tim H Brümmendorf, MD, Vladan Vucinic, MD, Dietger Niederwieser, MD, Melanie Märklin, PhD, Janet K. Peper, Malte Roerden, Reinhild Klein, Oliver Kohlbacher, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz
Journal: Blood
Blood (2018) 132 (Supplement 1): 4243.
https://doi.org/10.1182/blood-2018-99-113376
Published: 2018
Journal Articles

Validation of a Frailty Score Predicting Survival of Elderly, Non-Fit AML Patients Receiving Hypomethylating Therapy: Results of the Decider Trial

Valerie Hupfer, MD, Olga Grishina, Claudia Schmoor, Richard F. Schlenk, MD, Helmut R. Salih, MD, Martina Crysandt, Michael Heuser, MD, Hans-Walter Lindemann, MD, Carsten Müller-Tidow, MD, Gesine Bug, Ulrich Germing, MD, Katharina S. Götze, MD, Carsten Schwänen, Sebastian Scholl, MD, Aristoteles Giagounidis, Andreas Neubauer, Jürgen Krauter, MD, Arnold Ganser, MD, Hartmut Döhner, MD, Björn Hackanson, Gabriele Ihorst, Michael Lubbert, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 720.
https://doi.org/10.1182/blood-2018-99-115974
Published: 2018
Journal Articles

Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion

Anna M Paczulla, PhD, Kathrin Rothfelder, PhD, Simon Raffel, MD, Martina Konantz, PhD, Julia Steinbacher, PhD, Hui Wang, PhD, Marcelle Ndoh Mbarga, Thorsten Schaefer, PhD, Daniela Dörfel, MD, Mattia Falcone, Eva Nievergall, PhD, Claudia Tandler, MSc, Christoph Lutz, Pontus Lundberg, PhD, Lothar Kanz, Leticia Quintanilla-Martinez, MD, Alexander Steinle, Andreas Trumpp, Prof, PhD, Helmut R. Salih, MD, Claudia Lengerke, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 769.
https://doi.org/10.1182/blood-2018-99-118047
Published: 2018