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Todd Shearer
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Journal Articles

Preliminary anti-leukemia activity from A phase 1 study of cln-049, a novel anti-FLT3 x anti-CD3 bispecific T-cell engager, in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) and myelodysplastic syndrome (MDS)

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Maher Abdul-Hay, Colin Vale, Onyee Chan, Namrata Chandhok, Courtney DiNardo, Gary Schiller, Eunice Wang, Sanghee Hong, Kimo Bachiashvili, Mohammed Chaudhry, Kristy Kuplast-Barr, Kaida Wu, Todd Shearer, Thuy Hoang, Irina Shapiro, Máire Quigley, Jeffrey Jones, William Blum, David Sallman, Ghayas Issa
Journal: Blood
Blood (2025) 146 (Supplement 1): 768.
https://doi.org/10.1182/blood-2025-768
Published: 2025
Journal Articles

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study of Cln-049 for the Treatment of Acute Myeloid Leukemia Patients with Measurable Residual Disease

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Jonas S. Heitmann, Juliane S. Walz, Helmut R. Salih, Klaus H Metzeler, Daniel Heudobler, Felicitas R Thol, Hermann Einsele, Veit L. Buecklein, Pau Montesinos, Ana Alfonso Pierola, Gala Vega, Eduardo Rodriguez Arboli, Juan Miguel Bergua Burgues, Suhail Chaudhry, Judith Inumerable, Todd Shearer, Laura Liu, Sandeep Kaur, Kaida Wu, Marion Subklewe
Journal: Blood
Blood (2024) 144 (Supplement 1): 2883.1.
https://doi.org/10.1182/blood-2024-201478
Published: 2024
Journal Articles

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Study of CLN-978 (CD19XCD3XHSA) in Patients with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (B-NHL)

Free
Geoffrey P. Shouse, Kristie A. Blum, Julie E. Haydu, Jeremy S. Abramson, Mayur Narkhede, Andrew Ip, Jennifer S. Michaelson, Patrick A. Baeuerle, Kristan Meetze, Irina Shapiro, Todd Shearer, Judith Inumerable, Jeff Jones, Farrukh T. Awan
Journal: Blood
Blood (2023) 142 (Supplement 1): 3142.
https://doi.org/10.1182/blood-2023-181239
Published: 2023
Journal Articles

Pharmacodynamic Effects of Nirogacestat, a Gamma Secretase Inhibitor, on B-Cell Maturation Antigen in Healthy Participants

Free
Todd Shearer, Rex L. Williams, Jr., Mark Johnson, Ewa Cendrowicz, Cathrine Leonowens, Margaret Smith, Todd Baughman, Caroline J. Breitbach, L. Mary Smith, Michael Burgess, Shinta Cheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 3080–3081.
https://doi.org/10.1182/blood-2022-156811
Published: 2022