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Journal Articles

Prognostic impact of cytogenetic abnormalities detected by FISH in AL amyloidosis with daratumumab-based frontline therapy

Clinical Trials & Observations
Rajshekhar Chakraborty, Saurabh Zanwar, Ute Hegenbart, Divaya Bhutani, Morie A. Gertz, Angela Dispenzieri, Shaji Kumar, Anita D’Souza, Anannya Patwari, Andrew Cowan, GuiZhen Chen, Paolo Milani, Giovanni Palladini, Vaishali Sanchorawala, Geethika Bodanapu, Stefan O. Schönland, Suzanne Lentzsch, Eli Muchtar
Journal: Blood
Blood (2024) 144 (25): 2613–2624.
https://doi.org/10.1182/blood.2024025899
Published: 2024
Includes: Supplemental data
Journal Articles

Autologous Stem Cell Transplantation for Multiple Myeloma Patients Whose Myeloma Defining Event Was Slim

Iuliana Vaxman, Shaji Kumar, Inbar Cohen, Shai O. Shimony, Angela Dispenzieri, Francis Buadi, David Dingli, Martha Lacy, Eli Muchtar, Prashant Kapoor, William J. Hogan, Suzanne R Hayman, Nelson Leung, Wilson I. Gonsalves, Taxiarchis Kourelis, Rahma M Warsame, Morie A. Gertz
Journal: Blood
Blood (2024) 144 (Supplement 1): 7078.
https://doi.org/10.1182/blood-2024-205062
Published: 2024
Journal Articles

Flow Cytometry-Based Assessment of the Proportion of Monoclonal Plasma Cells in Synthetic Phase (S-phase) Is an Independent Marker of Adverse Prognosis in Patients with Newly Diagnosed Multiple Myeloma

Saurabh Zanwar, Dragan Jevremovic, Prashant Kapoor, Horatiu Olteanu, Francis Buadi, Pedro Horna, Wilson I. Gonsalves, Gregory Otteson, Suzanne R Hayman, Nadine Abdallah, Moritz Binder, Joselle Cook, Angela Dispenzieri, David Dingli, Morie A. Gertz, Taxiarchis Kourelis, Nelson Leung, Yi Lin, Eli Muchtar, Rahma M Warsame, Amie Fonder, Miriam Hobbs, Yi Lisa Hwa, Michelle G. Rogers, Robert A. Kyle, Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4704.
https://doi.org/10.1182/blood-2024-201052
Published: 2024
Journal Articles

Serum Immunoglobulins Are an Independent Prognostic Marker of Time to First Therapy in Newly Diagnosed Chronic Lymphocytic Leukemia (CLL) and Monoclonal B-Cell Lymphocytosis (MBL)

Yuan Yao, Kari G. Rabe, Cristine Allmer, Geffen Kleinstern, Nicholas J. Boddicker, Shulan Tian, Laura A. Bruins, Daniel R. O'Brien, Aaron D. Norman, Huihuang Yan, Timothy G. Call, Paul J. Hampel, Yucai Wang, Eli Muchtar, Saad S. Kenderian, Neil E. Kay, Celine M. Vachon, James R. Cerhan, Susan L. Slager, Esteban Braggio, Sameer A. Parikh
Journal: Blood
Blood (2024) 144 (Supplement 1): 4616.
https://doi.org/10.1182/blood-2024-194925
Published: 2024
Journal Articles

Trial in Progress: Phase II Study Evaluating Maintenance in Light Chain Amyloidosis (EMILIA)

Aytaj Mammadzadeh, Madhu Nagaraj, Manraj Sra, Rafla Hassan, Gaby E Perez Burbano, Alissa Peterson, Morie A. Gertz, Angela Dispenzieri, Rafael Fonseca, Saurabh Chhabra, Erin J Wiedmeier-Nutor, Leif Bergsagel, Julie L Rosenthal, Amy Hart, Anna Jones, Prashant Kapoor, Francis Buadi, Nelson Leung, Wilson I. Gonsalves, Suzanne R Hayman, Taxiarchis Kourelis, Rahma M Warsame, Joselle Cook, Moritz Binder, Vincent Rajkumar, David Dingli, Shaji Kumar, Taimur Sher, Udit Yadav, Eli Muchtar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4685.1.
https://doi.org/10.1182/blood-2024-208457
Published: 2024
Journal Articles

Light Chain Multiple Myeloma - Clinical Characteristics and Outcomes

Abiola Bolarinwa, Saurabh Zanwar, Nadine Abdallah, Francis Buadi, Suzanne R Hayman, Morie A. Gertz, Angela Dispenzieri, Eli Muchtar, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, David Dingli, Rahma M Warsame, Nelson Leung, Joselle Cook, Moritz Binder, Yi Lin, Yi Lisa Hwa, Michelle G. Rogers, Miriam Hobbs, Amie Fonder, Dragan Jevremovic, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 6950.
https://doi.org/10.1182/blood-2024-208468
Published: 2024
Journal Articles

Development of a Risk Prediction Model for 6-Month Early Mortality in Patients with Systemic Light Chain Amyloidosis Treated with Daratumumab-Based Frontline Therapy

George Mellgard, Abdul-hamid Bazarbachi, Saurabh Zanwar, Ute Hegenbart, Geethika Bodanapu, Divaya Bhutani, Guizhen Chen, Anita D'Souza, Angela Dispenzieri, Morie A. Gertz, Shaji Kumar, Suzanne Lentzsch, Paolo Milani, Eli Muchtar, Giovanni O. Palladini, Anannya Patwari, Vaishali Sanchorawala, Shikun Wang, Stefan O. Schönland, Rajshekhar Chakraborty, Andrew J. Cowan
Journal: Blood
Blood (2024) 144 (Supplement 1): 287.
https://doi.org/10.1182/blood-2024-202589
Published: 2024
Journal Articles

Evaluating the Interaction between Baseline Risk Stratification, Post-Transplant Measurable Residual Disease, and Long-Term Outcomes in Multiple Myeloma

Abiola Bolarinwa, Saurabh Zanwar, Nadine Abdallah, Sukriti Seth, Francis Buadi, Suzanne R Hayman, Morie A. Gertz, Angela Dispenzieri, Eli Muchtar, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, David Dingli, Rahma M Warsame, Nelson Leung, Joselle Cook, Moritz Binder, Yi Lin, Yi Lisa Hwa, Michelle G. Rogers, Miriam Hobbs, Amie Fonder, Dragan Jevremovic, S. Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4716.
https://doi.org/10.1182/blood-2024-211755
Published: 2024
Journal Articles

Impact of Serial Serum Free Light Chain Measurements on Response and Progression Assessments in Multiple Myeloma Patients with Measurable Disease

Elham Askari, Angela Dispenzieri, Francis K. Baudi, Suzanne R Hayman, Morie A. Gertz, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, David Dingli, Rahma M Warsame, Nelson Leung, Yi Lin, Eli Muchtar, Joselle Cook, Moritz Binder, Nadine Abdallah, Yi Lisa Hwa, Michelle G. Rogers, Miriam Hobbs, Amie Fonder, David Murray, Robert A. Kyle, Vincent Rajkumar, Shaji Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 1955.
https://doi.org/10.1182/blood-2024-208790
Published: 2024
Journal Articles

Outcomes with Venetoclax-Based Treatment in Patients with Covalent Bruton Tyrosine Kinase Inhibitor (cBTKi)-Treated, Chemotherapy-Naïve Chronic Lymphocytic Leukemia (CLL): An International Retrospective Study

Paul J. Hampel, Kari G. Rabe, Romain Guieze, Yucai Wang, Emmanuelle Ferrant, Saad S. Kenderian, Marie Sarah Dilhuydy, Eli Muchtar, Anne-Sophie Michallet, Jose F. Leis, Luca Inchiappa, Mazie Tsang, Aline Clavert, Talal Hilal, Stephane Lepretre, Ricardo D. Parrondo, Emmanuelle Tchernonog, Amber Koehler, Lin Wang, Susan M. Schwager, Susan L. Slager, Neil E. Kay, Luc-Matthieu Fornecker, Sameer A. Parikh, Loic Ysebaert
Journal: Blood
Blood (2024) 144 (Supplement 1): 1856.
https://doi.org/10.1182/blood-2024-198200
Published: 2024
Journal Articles

Model for Predicting Day-100 Stem Cell Transplant-Related Mortality in AL Amyloidosis

Eli Muchtar, Angela Dispenzieri, Vaishali Sanchorawala, Hamza Hassan, Raphael Mwangi, Matthew J. Maurer, Francis Buadi, Hans C. Lee, Muzaffar H. Qazilbash, Andrew Kin, Jeffrey A. Zonder, Sally Arai, Michelle M Chin, Rajshekhar Chakraborty, Suzanne Lentzsch, Hila Magen, Eden Shkury, Caitlin Sarubbi, Heather J. Landau, Stefan Schonland, Ute Hegenbart, Morie A. Gertz
Journal: Blood
Blood (2024) 144 (Supplement 1): 4681.
https://doi.org/10.1182/blood-2024-206496
Published: 2024
Journal Articles

Improved Survival with Daratumumab-Cybord Compared to Cybord As Frontline Therapy in Immunoglobulin Light Chain (AL) Amyloidosis

Binoy Yohannan, Matthew James Rees, Morie A. Gertz, Angela Dispenzieri, Francis Buadi, David Dingli, Nelson Leung, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, Joselle Cook, Moritz Binder, Martha Lacy, Suzanne R Hayman, Yi Lin, Yi Lisa Hwa, Michelle G Rogers, Miriam Hobbs, Amie Fonder, Ronald S Go, Rahma M Warsame, Vincent Rajkumar, Shaji Kumar, Eli Muchtar
Journal: Blood
Blood (2024) 144 (Supplement 1): 2400.
https://doi.org/10.1182/blood-2024-209102
Published: 2024
Journal Articles

Initial Results of a Phase 1 First-in-Human Study of Cemsidomide (CFT7455), a Novel MonoDAC TM Degrader, with Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Binod Dhakal, Andrew J. Yee, Paul G. Richardson, Sikander Ailawadhi, Saurabh Chhabra, Eli Muchtar, Jesús G. Berdeja, Shambavi Richard, Jeffrey V Matous, Urvi A. Shah, Mark A. Schroeder, Amro Ali, Leah Leahy, Riadh Lobbardi, Rong Chu, Eunju Hurh, Anthony S. Fiorino, Sagar Lonial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3366.
https://doi.org/10.1182/blood-2024-204255
Published: 2024
Journal Articles

Targeting the PI3K/AKT Pathway and Fatty Acid Synthase in AL Amyloidosis: Mechanistic Insights and Therapeutic Implications

Tal Zvida-Bloch, Eli Muchtar, Mali Salmon-Divon, Angela Dispenzieri, Benjamin Bender, Adrian Duek, Merav Leiba, Moshe E Gatt, Ofer Shpilberg, Oshrat Hershkovitz-Rokah
Journal: Blood
Blood (2024) 144 (Supplement 1): 3288.
https://doi.org/10.1182/blood-2024-206682
Published: 2024
Journal Articles

Characteristics and Outcomes of Patients with Second Hematological Malignancies after Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Binoy Yohannan, Angela Dispenzieri, Francis Buadi, David Dingli, Nelson Leung, Prashant Kapoor, Wilson I. Gonsalves, Taxiarchis Kourelis, Joselle Cook, Moritz Binder, Suzanne R Hayman, Yi Lin, Ronald S Go, Rahma M Warsame, Vincent Rajkumar, Shaji Kumar, Eli Muchtar, Hassan B Alkhateeb, William J. Hogan, Mark R. Litzow, Mrinal M. Patnaik, Aref Al-Kali, Abhishek Mangaonkar, Robert C Wolf, Mithun V Shah, Morie A. Gertz
Journal: Blood
Blood (2024) 144 (Supplement 1): 5149.
https://doi.org/10.1182/blood-2024-210932
Published: 2024
Journal Articles

Predictors of Liver Response in Light Chain (AL) Amyloidosis: A Study with 130 Patients

Nadia Toumeh, Matthew James Rees, Morie A. Gertz, Angela Dispenzieri, Binoy Yohannan, Suheil Albert Atallah-Yunes, Prashant Kapoor, Taxiarchis Kourelis, Nelson Leung, Suzanne R Hayman, Francis Buadi, David Dingli, Joselle Cook, Rahma M Warsame, Moritz Binder, Wilson I. Gonsalves, S. Vincent Rajkumar, Shaji Kumar, Eli Muchtar
Journal: Blood
Blood (2024) 144 (Supplement 1): 3308.
https://doi.org/10.1182/blood-2024-202059
Published: 2024
Journal Articles

Proteomic Determinants of Renal Organ Response in AL Amyloidosis

Matthew James Rees, Eli Muchtar, Suheil Albert Atallah-Yunes, Surendra Dasari, Nelson Leung, Morie A. Gertz, Angela Dispenzieri, Ellen McPhail, Shaji Kumar, Emilie Anderson, Christopher Dick, Taxiarchis Kourelis
Journal: Blood
Blood (2024) 144 (Supplement 1): 3305.
https://doi.org/10.1182/blood-2024-201168
Published: 2024
Journal Articles

Real World Outcomes with Venetoclax (Ven)-Based Therapies in Patients with Heavily Pretreated Relapsed/Refractory Multiple Myeloma (RRMM): A Mayo Clinic Comprehensive Cancer Center (MCCC) Experience

Ricardo D. Parrondo, Saurav Das, Hanna Sledge, Abiola Bolarinwa, Jamie Elliott, Andre Fernandez, David O. Hodge, Leif Bergsagel, Rafael Fonseca, Prashant Kapoor, Francis Buadi, Morie A. Gertz, Angela Dispenzieri, Vivek Roy, Taimur Sher, Moritz Binder, Nadine Abdallah, Saurabh Chhabra, S. Vincent Rajkumar, Wilson I. Gonsalves, Joselle Cook, David Dingli, Saurabh Zanwar, Yi Lin, Eli Muchtar, Caitlin Wilson, Udit Yadav, Rahma M Warsame, J E Wiedmeier-Nutor, Taxiarchis Kourelis, Nelson Leung, Madhu Nagaraj, Mustaqeem A. Siddiqui, Linda B. Baughn, Shaji Kumar, Asher A. Chanan-Khan, Sikander Ailawadhi
Journal: Blood
Blood (2024) 144 (Supplement 1): 1981.
https://doi.org/10.1182/blood-2024-208294
Published: 2024
Journal Articles

Outcomes of Venetoclax-Based Treatment Combinations in Relapsed/Refractory Multiple Myeloma: Real-World Practice Patterns and Impact of Cytogenetics on Outcomes

Abiola Bolarinwa, Madhu Nagaraj, Saurabh Zanwar, Nadine Abdallah, P. Leif Bergsagel, Moritz Binder, Francis Buadi, Saurabh Chhabra, Joselle Cook, David Dingli, Angela Dispenzieri, Morie A. Gertz, Wilson I. Gonsalves, Suzanne R Hayman, Prashant Kapoor, Taxiarchis Kourelis, Nelson Leung, Yi Lin, Eli Muchtar, Ricardo D. Parrondo, Vivek Roy, Taimur Sher, Mustaqeem A. Siddiqui, Rahma M Warsame, Amie Fonder, Miriam Hobbs, Yi Lisa Hwa, Michelle G. Rogers, Udit Yadav, J E Wiedmeier-Nutor, Dragan Jevremovic, Linda B. Baughn, Vincent Rajkumar, Rafael Fonseca, Sikander Ailawadhi, Shaji Kumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4728.
https://doi.org/10.1182/blood-2024-208736
Published: 2024
Journal Articles

Impact of Multiple High-Risk Cytogenetic Abnormalities on the Survival Outcomes of Patients with Primary Plasma Cell Leukemia

Adrian A Almodovar Diaz, Samhar Alouch, Angela Dispenzieri, Udit Yadav, Francis Buadi, David Dingli, Eli Muchtar, Nelson Leung, Taxiarchis Kourelis, Rahma M Warsame, Ronald S Go, Moritz Binder, Joselle Cook, Miriam Hobbs, Yi Lisa Hwa, Amie Fonder, Michelle G. Rogers, Suzanne R Hayman, Yi Lin, Mustaqeem A. Siddiqui, Robert A. Kyle, Morie A. Gertz, Vincent Rajkumar, Wilson I. Gonsalves
Journal: Blood
Blood (2024) 144 (Supplement 1): 3315.
https://doi.org/10.1182/blood-2024-200267
Published: 2024