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Rudy Fuentes
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Journal Articles

Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Yuhuan Wang, Vincent Hayes, Danuta Jarocha, Xiuli Sim, Dawn C. Harper, Rudy Fuentes, Spencer K. Sullivan, Paul Gadue, Stella T. Chou, Beverly J. Torok-Storb, Michael S. Marks, Deborah L. French, Mortimer Poncz
Journal: Blood
Blood (2015) 125 (23): 3627–3636.
https://doi.org/10.1182/blood-2014-08-593053
Published: 2015
Includes: Supplemental data
Journal Articles

A Human-Specific, Platelet-Targeted, Thrombin-Activatable Urokinase (PLT/uPA-T) Demonstrates Selective Thromboprophylactic Properties in Two in Vivo Models

Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent Hayes, Douglas B. Cines, MD, Vladimir R Muzykantov, MDPhD, Sergei V. Zaytsev, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2014) 124 (21): 579.
https://doi.org/10.1182/blood.V124.21.579.579
Published: 2014
Journal Articles

Challenges and promises for the development of donor-independent platelet transfusions

Michele P. Lambert, Spencer K. Sullivan, Rudy Fuentes, Deborah L. French, Mortimer Poncz
Journal: Blood
Blood (2013) 121 (17): 3319–3324.
https://doi.org/10.1182/blood-2012-09-455428
Published: 2013
Journal Articles

Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs)

Yuhuan Wang, PhD, Vincent M. Hayes, Lin Lu, Ph.D, Xiaoji Chen, Rudy Fuentes, PhD, Qiang Jeremy Wen, MD, PhD, Stella T Chou, MD, John Crispino, PhD, Patrick Paddison, PhD, Deborah L. French, PhD, Beverly Torok-Storb, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2012) 120 (21): 3450.
https://doi.org/10.1182/blood.V120.21.3450.3450
Published: 2012
Journal Articles

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Valerie Tutwiler, Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent M. Hayes, Sergei V. Zaytsev, PhD, X. Long Zheng, MD, PhD, Douglas B. Cines, MD, Steven E. McKenzie, MD, PhD, John W. Weisel, Ph.D., Mortimer Poncz, MD, Lubica Rauova, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 635.
https://doi.org/10.1182/blood.V120.21.635.635
Published: 2012
Journal Articles

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Rudy Fuentes, PhD, Hyun Sook Ahn, Vincent M. Hayes, Valerie Tutwiler, Yuhuan Wang, PhD, Daniel W. Bougie, PhD, M. Anna Kowalska, PhD, Lubica Rauova, M.D., Ph.D., Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R Muzykantov, MD PhD, Mortimer Poncz, MD, Sergei Zaitsev, PhD
Journal: Blood
Blood (2012) 120 (21): 1171.
https://doi.org/10.1182/blood.V120.21.1171.1171
Published: 2012
Journal Articles

Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction

Yuhuan Wang, Ronghua Meng, Vincent Hayes, Rudy Fuentes, Xiang Yu, Charles S. Abrams, Harry F. G. Heijnen, Gerd A. Blobel, Michael S. Marks, Mortimer Poncz
Journal: Blood
Blood (2011) 118 (23): 6183–6191.
https://doi.org/10.1182/blood-2011-06-363580
Published: 2011
Includes: Supplemental data
Journal Articles

Expansion of Platelets for Transfusion

Rudy Fuentes, Yuhuan Wang, Mortimer Poncz, MD
Journal: Blood
Blood (2010) 116 (21): SCI-47.
https://doi.org/10.1182/blood.V116.21.SCI-47.SCI-47
Published: 2010
Journal Articles

Platelet-Targeted Pro-Urokinase as a Novel Thromboprophylaxis Fibrinolytic Strategy

Rudy Fuentes, M. Anna Kowalska, PhD, Samira Tliba, Daniel W. Bougie, PhD, Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R. Muzykantov, Mortimer Poncz, MD, Sergei Zaitsev
Journal: Blood
Blood (2010) 116 (21): 3339.
https://doi.org/10.1182/blood.V116.21.3339.3339
Published: 2010
Journal Articles

Infusing Mature Megakaryocytes Into Mice Yields Functional Platelets: Biological and Clinical Implications.

Rudy Fuentes, BS, Yuhuan Wang, PhD, Jessica Hirsh, BS, Mortimer Poncz, MD
Journal: Blood
Blood (2009) 114 (22): 225.
https://doi.org/10.1182/blood.V114.22.225.225
Published: 2009
Journal Articles

Structural and therapeutic insights from the species specificity and in vivo antithrombotic activity of a novel αIIb-specific αIIbβ3 antagonist

Robert Blue, M. Anna Kowalska, Jessica Hirsch, Marta Murcia, Christin A. Janczak, Amanda Harrington, Marketa Jirouskova, Jihong Li, Rudy Fuentes, Michael A. Thornton, Marta Filizola, Mortimer Poncz, Barry S. Coller
Journal: Blood
Blood (2009) 114 (1): 195–201.
https://doi.org/10.1182/blood-2008-08-169243
Published: 2009
Includes: Multimedia, Supplemental data
Journal Articles

Structural and Therapeutic Insights from the Species Specificity and in Vivo Antithrombotic Activity of a Novel αIIb-Specific αIIbβ3 Antagonist

Robert Blue, M. Anna Kowalska, PhD, Marta Murcia, PhD, Christin A. Janczak, Marketa Jirouskova, PhD, Jihong Li, MD, Amanda Harrington, Rudy Fuentes, Michael A. Thornton, PhD, Marta Filizola, Mortimer Poncz, MD, Barry S. Coller, MD
Journal: Blood
Blood (2008) 112 (11): 256.
https://doi.org/10.1182/blood.V112.11.256.256
Published: 2008