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Sergei Zaitsev
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Journal Articles

Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes

Sanjay Khandelwal, Ayiesha Barnes, Lubica Rauova, Amrita Sarkar, Ann H. Rux, Serge V. Yarovoi, S. Sergei Zaitsev, John D. Lambris, Sooho S. Myoung, Alexandra Johnson, Grace M. Lee, Madelaine Duarte, Mortimer Poncz, Gowthami M. Arepally, Douglas B. Cines
Journal: Blood
Blood (2021) 138 (21): 2106–2116.
https://doi.org/10.1182/blood.2020009487
Published: 2021
Includes: Supplemental data
Journal Articles

FcRn augments induction of tissue factor activity by IgG-containing immune complexes

Douglas B. Cines, Sergei Zaitsev, Lubica Rauova, Ann H. Rux, Victoria Stepanova, Sriram Krishnaswamy, Amrita Sarkar, M. Anna Kowalska, Guohua Zhao, Alan E. Mast, Laurence J. Blumberg, Keith R. McCrae, Mortimer Poncz, Jonathan J. Hubbard, Michal Pyzik, Richard S. Blumberg
Journal: Blood
Blood (2020) 135 (23): 2085–2093.
https://doi.org/10.1182/blood.2019001133
Published: 2020
Includes: Supplemental data
Journal Articles

A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis

Hyunsook Ahn, MSc, John Tkaczynski, BS, Khalil Bdeir, PhD, Victoria Stepanova, Douglas B. Cines, MD, Mortimer Poncz, MD, Sergei Zaitsev
Journal: Blood
Blood (2019) 134 (Supplement_1): 3627.
https://doi.org/10.1182/blood-2019-124501
Published: 2019
Journal Articles

Fibrinolysis of Contracted Blood Clots Depends on Whether Plasminogen Activator Acts from inside or Outside

Valerie Tutwiler, PhD, Alina D. Peshkova, MS, Giang Le Minh, Sergei Zaitsev, Rustem I. Litvinov, Douglas B. Cines, MD, John W. Weisel, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3773.
https://doi.org/10.1182/blood-2018-99-119659
Published: 2018
Journal Articles

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Rudy Fuentes, PhD, Hyun Sook Ahn, Vincent M. Hayes, Valerie Tutwiler, Yuhuan Wang, PhD, Daniel W. Bougie, PhD, M. Anna Kowalska, PhD, Lubica Rauova, M.D., Ph.D., Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R Muzykantov, MD PhD, Mortimer Poncz, MD, Sergei Zaitsev, PhD
Journal: Blood
Blood (2012) 120 (21): 1171.
https://doi.org/10.1182/blood.V120.21.1171.1171
Published: 2012
Journal Articles

Targeting recombinant thrombomodulin fusion protein to red blood cells provides multifaceted thromboprophylaxis

Sergei Zaitsev, M. Anna Kowalska, Michael Neyman, Ronald Carnemolla, Samira Tliba, Bi-Sen Ding, Aaron Stonestrom, Dirk Spitzer, John P. Atkinson, Mortimer Poncz, Douglas B. Cines, Charles T. Esmon, Vladimir R. Muzykantov
Journal: Blood
Blood (2012) 119 (20): 4779–4785.
https://doi.org/10.1182/blood-2011-12-398149
Published: 2012
Includes: Multimedia, Supplemental data
Journal Articles

Flow-dependent channel formation in clots by an erythrocyte-bound fibrinolytic agent

Brief Report
Kathryn C. Gersh, Sergei Zaitsev, Douglas B. Cines, Vladimir Muzykantov, John W. Weisel
Journal: Blood
Blood (2011) 117 (18): 4964–4967.
https://doi.org/10.1182/blood-2010-10-310409
Published: 2011
Includes: Multimedia, Supplemental data
Journal Articles

Platelet-Targeted Pro-Urokinase as a Novel Thromboprophylaxis Fibrinolytic Strategy

Rudy Fuentes, M. Anna Kowalska, PhD, Samira Tliba, Daniel W. Bougie, PhD, Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R. Muzykantov, Mortimer Poncz, MD, Sergei Zaitsev
Journal: Blood
Blood (2010) 116 (21): 3339.
https://doi.org/10.1182/blood.V116.21.3339.3339
Published: 2010
Journal Articles

Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation

Sergei Zaitsev, Dirk Spitzer, Juan-Carlos Murciano, Bi-Sen Ding, Samira Tliba, M. Anna Kowalska, Oscar A. Marcos-Contreras, Alice Kuo, Victoria Stepanova, John P. Atkinson, Mortimer Poncz, Douglas B. Cines, Vladimir R. Muzykantov
Journal: Blood
Blood (2010) 115 (25): 5241–5248.
https://doi.org/10.1182/blood-2010-01-261610
Published: 2010
Includes: Supplemental data
Journal Articles

Nuclear translocation of urokinase-type plasminogen activator

Victoria Stepanova, Tatiana Lebedeva, Alice Kuo, Serge Yarovoi, Sergei Tkachuk, Sergei Zaitsev, Khalil Bdeir, Inna Dumler, Michael S. Marks, Yelena Parfyonova, Vsevolod A. Tkachuk, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2008) 112 (1): 100–110.
https://doi.org/10.1182/blood-2007-07-104455
Published: 2008
Includes: Multimedia, Supplemental data
Journal Articles

Human complement receptor type 1–directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysis

Sergei Zaitsev, Kristina Danielyan, Juan-Carlos Murciano, Kumkum Ganguly, Tatiana Krasik, Ronald P. Taylor, Steven Pincus, Steven Jones, Douglas B. Cines, Vladimir R. Muzykantov
Journal: Blood
Blood (2006) 108 (6): 1895–1902.
https://doi.org/10.1182/blood-2005-11-012336
Published: 2006