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Journal Articles

Neutrophil Extracellular Traps (NETs) Thrombogenicity and Endothelial Cell Toxicity Are Ameliorated By Platelet Factor 4 (PF4): Implications to the Treatment of Sepsis

Anh T.P. Ngo, Amrita Sarkar, Nathan Levine, Veronica Bochenek, Guohua Zhao, Lubica Rauova, M. Anna Kowalska, Kaitlyn Eckart, Nilam S. Mangalmurti, Ann Rux, Douglas B. Cines, Mortimer Poncz, Kandace Gollomp
Journal: Blood
Blood (2022) 140 (Supplement 1): 5529–5530.
https://doi.org/10.1182/blood-2022-169709
Published: 2022
Journal Articles

Platelet Factor 4 (PF4) Modulates the Prothrombotic Nature of Neutrophil-Extracellular Traps (NETs): Therapeutic Implications of a NET-Stabilization Strategy

Anh T.P. Ngo, Irene Yarovoi, Guohua Zhao, Amrita Sarkar, Lubica Rauova, M. Anna Kowalska, Mortimer Poncz, Kandace Gollomp
Journal: Blood
Blood (2021) 138 (Supplement 1): 2096.
https://doi.org/10.1182/blood-2021-153352
Published: 2021
Journal Articles

FcRn augments induction of tissue factor activity by IgG-containing immune complexes

Douglas B. Cines, Sergei Zaitsev, Lubica Rauova, Ann H. Rux, Victoria Stepanova, Sriram Krishnaswamy, Amrita Sarkar, M. Anna Kowalska, Guohua Zhao, Alan E. Mast, Laurence J. Blumberg, Keith R. McCrae, Mortimer Poncz, Jonathan J. Hubbard, Michal Pyzik, Richard S. Blumberg
Journal: Blood
Blood (2020) 135 (23): 2085–2093.
https://doi.org/10.1182/blood.2019001133
Published: 2020
Includes: Supplemental data
Journal Articles

Inhibition of Neutrophil Extracellular Trap Release through the Disruption of PAD4 Leads to Decreased Neutrophil and Platelet Accumulation at Sites of Venular Vascular Injury in a Murine Model of Heparin-Induced Thrombocytopenia

Kandace Gollomp, MD, Vincent Hayes, Ian Johnston, BS, Minna Kim, Guohua Zhao, Lubica Rauova, MD PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2268.
https://doi.org/10.1182/blood.V130.Suppl_1.2268.2268
Published: 2017
Journal Articles

Platelet Factor 4 (PF4)-Mediated Neutrophil Extracellular Trap Compaction Limits Endothelial Injury and Promotes Survival Following Lipopolysaccharide Challenge

Kandace Gollomp, MD, Ian Johnston, BS, Minna Kim, Li Zhai, Guohua Zhao, M. Anna Kowalska, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 997.
https://doi.org/10.1182/blood.V130.Suppl_1.997.997
Published: 2017
Journal Articles

The NET Effect: Platelet Factor 4 and DNA-Histone Interactions in Sepsis

Kandace Gollomp, MD, Johnston Ian, Diarra Fatoumata, Guohua Zhao, Sriram Krishnaswamy, PhD MD, Mortimer Poncz, MD, M. Anna Kowalska, PhD
Journal: Blood
Blood (2015) 126 (23): 2197.
https://doi.org/10.1182/blood.V126.23.2197.2197
Published: 2015
Journal Articles

A Proposed Role for Platelet Factor 4 in Histone Pathobiology in Sepsis

M. Anna Kowalska, PhD, Guohua Zhao, PhD, Ian Johnston, BS, Elsa Treffeisen, BA, Fatoumata Diarra, Sriram Krishnaswamy, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2014) 124 (21): 98.
https://doi.org/10.1182/blood.V124.21.98.98
Published: 2014
Journal Articles

Targeted Gene Correction of Glanzmann Thrombasthenia Induced Pluripotent Stem Cells Restores Surface Expression and Fibrinogen Binding of Integrin αIIbβ3,

Spencer Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Guohua Zhao, PhD, Lin Lu, PhD, Michele Lambert, MD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD
Journal: Blood
Blood (2011) 118 (21): 4173.
https://doi.org/10.1182/blood.V118.21.4173.4173
Published: 2011
Journal Articles

Histones, Like Platelet Factor 4 (PF4), Affect Generation of Activated Protein C: Implications for the Pathogenesis of Severe Sepsis

M. Anna Kowalska, PhD, Guohua Zhao, PhD, George David, III, Mortimer Poncz, MD
Journal: Blood
Blood (2011) 118 (21): 530.
https://doi.org/10.1182/blood.V118.21.530.530
Published: 2011