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Journal Articles

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Ian Johnston, Amrita Sarkar, Vincent Hayes, Gavin T. Koma, Gowthami M. Arepally, Junmei Chen, Dominic W. Chung, José A. López, Douglas B. Cines, Lubica Rauova, Mortimer Poncz

Blood (2020) 135 (15): 1270–1280.

https://doi.org/10.1182/blood.2018881607

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

Randolph Lyde, PhD, Hyunsook Ahn, Vincent Hayes, Sergei Zaistev, PhD, Shu-Wha Lin, PhD, Zaverio M. Ruggeri, MD, Renhao Li, PhD, Vladimir Muzykantov, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2018) 132 (Supplement 1): 990.

https://doi.org/10.1182/blood-2018-99-115262

Published: 2018

Journal Articles

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Jing Dai, Daria Madeeva, Vincent Hayes, Hyun Sook Ahn, Valerie Tutwiler, Gowthami M. Arepally, Douglas B. Cines, Mortimer Poncz, Lubica Rauova

Blood (2018) 132 (7): 727–734.

https://doi.org/10.1182/blood-2018-02-830737

Published: 2018

Includes: Supplemental data

Journal Articles

Inhibition of Neutrophil Extracellular Trap Release through the Disruption of PAD4 Leads to Decreased Neutrophil and Platelet Accumulation at Sites of Venular Vascular Injury in a Murine Model of Heparin-Induced Thrombocytopenia

Kandace Gollomp, MD, Vincent Hayes, Ian Johnston, BS, Minna Kim, Guohua Zhao, Lubica Rauova, MD PhD, Mortimer Poncz, MD

Blood (2017) 130 (Supplement 1): 2268.

https://doi.org/10.1182/blood.V130.Suppl_1.2268.2268

Published: 2017

Journal Articles

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

Xiuli Sim, Danuta Jarocha, Vincent Hayes, Hayley A. Hanby, Michael S. Marks, Rodney M. Camire, Deborah L. French, Mortimer Poncz, Paul Gadue

Blood (2017) 130 (2): 192–204.

https://doi.org/10.1182/blood-2017-01-761049

Published: 2017

Includes: Supplemental data

Journal Articles

FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology

Karen K. Vo, Danuta J. Jarocha, Randolph B. Lyde, Vincent Hayes, Christopher S. Thom, Spencer K. Sullivan, Deborah L. French, Mortimer Poncz

Blood (2017) 129 (26): 3486–3494.

https://doi.org/10.1182/blood-2017-02-770958

Published: 2017

Includes: Supplemental data

Journal Articles

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Valerie Tutwiler, Daria Madeeva, Hyun Sook Ahn, Izabella Andrianova, Vincent Hayes, X. Long Zheng, Douglas B. Cines, Steven E. McKenzie, Mortimer Poncz, Lubica Rauova

Blood (2016) 127 (4): 464–472.

https://doi.org/10.1182/blood-2013-11-539262

Published: 2016

Includes: Supplemental data

Journal Articles

Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Yuhuan Wang, Vincent Hayes, Danuta Jarocha, Xiuli Sim, Dawn C. Harper, Rudy Fuentes, Spencer K. Sullivan, Paul Gadue, Stella T. Chou, Beverly J. Torok-Storb, Michael S. Marks, Deborah L. French, Mortimer Poncz

Blood (2015) 125 (23): 3627–3636.

https://doi.org/10.1182/blood-2014-08-593053

Published: 2015

Includes: Supplemental data

Journal Articles

Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells

Ji-Yoon Noh, PhD, Shilpa Gandre-Babbe, PhD, Yuhuan Wang, PhD, Vincent Hayes, BS, Yu Yao, Paul Gadue, PhD, Spencer Sullivan, MD, Stella T. Chou, MD, Vikram R Paralkar, MD, Kellie R Machlus, PhD, Joseph E. Italiano, PhD, Michael Kyba, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Mitchell J. Weiss, MD PhD

Blood (2014) 124 (21): 3846.

https://doi.org/10.1182/blood.V124.21.3846.3846

Published: 2014

Journal Articles

Comparative Analysis of Infused “Static”, Ex Vivo-Generated Platelets Vs. Infused Megakaryocytes-Generated Platelets: A Cautionary Tale

Yuhuan Wang, PhD, Vincent Hayes, Danuta Jarocha, PhD, Mortimer Poncz, MD

Blood (2014) 124 (21): 2881.

https://doi.org/10.1182/blood.V124.21.2881.2881

Published: 2014

Journal Articles

New Insights into the Prothrombotic State of Heparin-Induced Thrombocytopenia (HIT) Using a Novel Microfluidic System: The Endothelial Lining and “Rolling Barrage” of Activation

Vincent Hayes, Ian Johnston, BS, Douglas B. Cines, MD, Lubica Rauova, MD PhD, Mortimer Poncz, MD

Blood (2014) 124 (21): 574.

https://doi.org/10.1182/blood.V124.21.574.574

Published: 2014

Journal Articles

A Human-Specific, Platelet-Targeted, Thrombin-Activatable Urokinase (PLT/uPA-T) Demonstrates Selective Thromboprophylactic Properties in Two in Vivo Models

Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent Hayes, Douglas B. Cines, MD, Vladimir R Muzykantov, MDPhD, Sergei V. Zaytsev, PhD, Mortimer Poncz, MD

Blood (2014) 124 (21): 579.

https://doi.org/10.1182/blood.V124.21.579.579

Published: 2014

Journal Articles

Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin

Douglas B. Cines, Tatiana Lebedeva, Chandrasekaran Nagaswami, Vincent Hayes, Walter Massefski, Rustem I. Litvinov, Lubica Rauova, Thomas J. Lowery, John W. Weisel

Blood (2014) 123 (10): 1596–1603.

https://doi.org/10.1182/blood-2013-08-523860

Published: 2014

Includes: Supplemental data

Journal Articles

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

Huiying Zhi, Lubica Rauova, Vincent Hayes, Cunji Gao, Brian Boylan, Debra K. Newman, Steven E. McKenzie, Brian C. Cooley, Mortimer Poncz, Peter J. Newman

Blood (2013) 121 (10): 1858–1867.

https://doi.org/10.1182/blood-2012-07-443325

Published: 2013

Includes: Supplemental data

Journal Articles

Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction

Yuhuan Wang, Ronghua Meng, Vincent Hayes, Rudy Fuentes, Xiang Yu, Charles S. Abrams, Harry F. G. Heijnen, Gerd A. Blobel, Michael S. Marks, Mortimer Poncz

Blood (2011) 118 (23): 6183–6191.

https://doi.org/10.1182/blood-2011-06-363580

Published: 2011

Includes: Supplemental data

Journal Articles

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT

M. Anna Kowalska, Sriram Krishnaswamy, Lubica Rauova, Li Zhai, Vincent Hayes, Karine Amirikian, Jeffrey D. Esko, Daniel W. Bougie, Richard H. Aster, Douglas B. Cines, Mortimer Poncz

Blood (2011) 118 (10): 2882–2888.

https://doi.org/10.1182/blood-2011-02-335208

Published: 2011

Includes: Supplemental data

Journal Articles

Heparin-Induced Thrombocytopenia Antibodies Inhibit PF4-Dependent Enhancement of Activated Protein C Formation by Binding to Antigenic Complexes Formed with the Chondroitin Sulfate Side-Chain of Thrombomodulin

M. Anna Kowalska, PhD, Lubica Rauova, PhD, Vincent Hayes, BA, Douglas B. Cines, MD, Daniel W. Bougie, PhD, Richard H. Aster, MD, Sriram Krishnaswamy, PhD, Mortimer Poncz, MD

Blood (2010) 116 (21): 721.

https://doi.org/10.1182/blood.V116.21.721.721

Published: 2010

NARROW

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Inhibition of Neutrophil Extracellular Trap Release through the Disruption of PAD4 Leads to Decreased Neutrophil and Platelet Accumulation at Sites of Venular Vascular Injury in a Murine Model of Heparin-Induced Thrombocytopenia

Identifying and enriching platelet-producing human stem cell–derived megakaryocytes using factor V uptake

FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Inducible Gata1 Suppression As a Novel Strategy to Expand Physiologic Megakaryocyte Production from Embryonic Stem Cells

Comparative Analysis of Infused “Static”, Ex Vivo-Generated Platelets Vs. Infused Megakaryocytes-Generated Platelets: A Cautionary Tale

New Insights into the Prothrombotic State of Heparin-Induced Thrombocytopenia (HIT) Using a Novel Microfluidic System: The Endothelial Lining and “Rolling Barrage” of Activation

A Human-Specific, Platelet-Targeted, Thrombin-Activatable Urokinase (PLT/uPA-T) Demonstrates Selective Thromboprophylactic Properties in Two in Vivo Models

Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT

Heparin-Induced Thrombocytopenia Antibodies Inhibit PF4-Dependent Enhancement of Activated Protein C Formation by Binding to Antigenic Complexes Formed with the Chondroitin Sulfate Side-Chain of Thrombomodulin

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American Society of Hematology

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American Society of Hematology

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