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Journal Articles

A prospective, blinded study of a PF4-dependent assay for HIT diagnosis

Bethany Samuelson Bannow, Deepti M. Warad, Curtis G. Jones, Shannon M. Pechauer, Brian R. Curtis, Daniel W. Bougie, Ruchika Sharma, Diane E. Grill, Mary W. Redman, Parisa R. Khalighi, Rachel R. Leger, Rajiv K. Pruthi, Dong Chen, Daniel E. Sabath, Richard H. Aster, David A. Garcia, Anand Padmanabhan

Blood (2021) 137 (8): 1082–1089.

https://doi.org/10.1182/blood.2020008195

Published: 2021

Includes: Supplemental data

Journal Articles

Serologic Characterization of Antibodies in Patients Experiencing Piperacillin-Induced Immune Thrombocytopenia

Mark Rasmussen, Daniel W. Bougie, PhD, Gregory H. Denomme, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 1078.

https://doi.org/10.1182/blood-2019-130966

Published: 2019

Journal Articles

Cross-Reactivity of Drug-Dependent Antibodies in Patients with Immune Thrombocytopenia Induced By Beta-Lactam Antibiotics

Matthew John Slaught, BS, Daniel W. Bougie, PhD, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 2350.

https://doi.org/10.1182/blood-2019-131375

Published: 2019

Journal Articles

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

Daniel W. Bougie, PhD, Jessica Sutton, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 2349.

https://doi.org/10.1182/blood-2019-126815

Published: 2019

Journal Articles

The Platelet Factor-4 (PF4)-Dependent p-Selectin Expression Assay (PEA) Is Highly Accurate for the Detection of Pathogenic HIT Antibodies: Results of a 440-Sample Prospective Blinded Study

Deepti M. Warad, MD, Bethany T Samuelson Bannow, MD, Curtis Jones, BS, Shannon Pechauer, Brian R. Curtis, PhD, Daniel W. Bougie, PhD, Parisa R Khalighi, BS, Diane E. Grill, MS, Rachel Leger, BAE, Ruchika Sharma, MD, Dong Chen, MD PhD, Richard H. Aster, MD, David A. Garcia, MD, Anand Padmanabhan, MD PhD

Blood (2018) 132 (Supplement 1): 416.

https://doi.org/10.1182/blood-2018-99-112475

Published: 2018

Journal Articles

Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies

Brian R. Curtis, Yen-Michael S. Hsu, Nikolai Podoltsev, Jill Lacy, Susanna Curtis, Michael S. Samuel, Kristin Zutavern, Robert A. DeSimone, Daniel W. Bougie, Richard H. Aster

Blood (2018) 131 (13): 1486–1489.

https://doi.org/10.1182/blood-2017-10-812461

Published: 2018

Includes: Supplemental data

Journal Articles

Normal plasma IgG inhibits HIT antibody–mediated platelet activation: implications for therapeutic plasma exchange

Curtis G. Jones, Shannon M. Pechauer, Brian R. Curtis, Daniel W. Bougie, Richard H. Aster, Anand Padmanabhan

Blood (2018) 131 (6): 703–706.

https://doi.org/10.1182/blood-2017-08-803031

Published: 2018

Includes: Supplemental data

Journal Articles

A New Assay for Platelet-Activating HIT Antibodies, the PEA, Is Specific, Reproducible and Relatively Independent of the Choice of Platelet Donor

Shannon Pechauer, Curtis Jones, BS, Daniel W. Bougie, PhD, Brian R. Curtis, PhDMT(ASCP), Richard H. Aster, MD, Anand Padmanabhan, MD PhD

Blood (2017) 130 (Supplement 1): 458.

https://doi.org/10.1182/blood.V130.Suppl_1.458.458

Published: 2017

Journal Articles

Immunoglobulin G in Normal Plasma Inhibits HIT Antibody-Mediated Platelet Activation: Implications for Therapeutic Plasma Exchange Treatment in HIT

Curtis Jones, BS, Shannon Pechauer, Brian R. Curtis, PhDMT(ASCP), Daniel W. Bougie, PhD, Richard H. Aster, MD, Anand Padmanabhan, MD PhD

Blood (2017) 130 (Supplement 1): 2402.

https://doi.org/10.1182/blood.V130.Suppl_1.2402.2402

Published: 2017

Journal Articles

Autoimmune Thrombocytopenia in Mice Immunized with Allogeneic Platelets: A Model for Post-Transfusion Purpura (PTP)?

Daniel W. Bougie, PhD, Jessica Sutton, Richard H. Aster, MD

Blood (2016) 128 (22): 168.

https://doi.org/10.1182/blood.V128.22.168.168

Published: 2016

Journal Articles

A Novel PF4-Dependent P-Selectin Expression Assay (PEA) Facilitates Early Detection of Pathogenic HIT Antibodies: Implications for Diagnosis and Treatment of HIT

Anand Padmanabhan, MBBS, MA, PhD, Curtis G Jones, Shannon M Pechauer, Brian R Curtis, PhD D(ABMLI) MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia J Sullivan, Mehraboon S. Irani, MBBChir, Binod Dhakal, MDMS, Lisa M. Baumann Kreuziger, MD MS, Brenda M. Pierce, MD, Richard H. Aster, MD

Blood (2016) 128 (22): 2599.

https://doi.org/10.1182/blood.V128.22.2599.2599

Published: 2016

Journal Articles

Intravenous Immunoglobulin (IVIg) Is a Highly Effective Treatment for HIT: Critical Role of the IgG Fc Domain in Inhibiting HIT Antibody-Mediated Platelet Activation

Anand Padmanabhan, MBBS, MA, PhD, Curtis G Jones, Shannon M Pechauer, Barbara J. Bryant, MD, Jack B. Alperin, MD, Mehraboon S. Irani, MBBChir, Binod Dhakal, MDMS, Brian R Curtis, PhD D(ABMLI) MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia J Sullivan, Renren Wen, PhD, Demin Wang, PhD, Richard H. Aster, MD

Blood (2016) 128 (22): 2600.

https://doi.org/10.1182/blood.V128.22.2600.2600

Published: 2016

Journal Articles

Binding of Quinine-Dependent Monoclonal Antibodies to Gpiib/Iiia Appears to Involve Drug-Induced Modulation of Antibody Affinity

Daniel W. Bougie, PhD, Julie A. Peterson, PhD, Mark Rasmussen, Richard H. Aster, MD

Blood (2015) 126 (23): 2246.

https://doi.org/10.1182/blood.V126.23.2246.2246

Published: 2015

Journal Articles

Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin alphaIIbbeta3

Jianghai Zhu, PhD, Jieqing Zhu, PhD, Daniel W. Bougie, PhD, Richard H. Aster, MD, Timothy A. Springer, PhD

Blood (2015) 126 (23): 1063.

https://doi.org/10.1182/blood.V126.23.1063.1063

Published: 2015

Journal Articles

Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD

Robert R. Montgomery, MD, Veronica H Flood, MD, Jieqing Zhu, PhD, Pamela A Christopherson, Peter J. Newman, PhD, Daniel W. Bougie, PhD, Patti Morateck

Blood (2015) 126 (23): 1107.

https://doi.org/10.1182/blood.V126.23.1107.1107

Published: 2015

Journal Articles

A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis (HIT)

Anand Padmanabhan, MBBS, MA, PhD, Curtis Jones, Brian R Curtis, MS, MT(ASCP)SBB, Daniel W. Bougie, PhD, Mia Sullivan, Namrata Peswani, MD MBBS, Janice McFarland, MD, Daniel Eastwood, Demin Wang, PhD, Richard H. Aster, MD

Blood (2015) 126 (23): 764.

https://doi.org/10.1182/blood.V126.23.764.764

Published: 2015

Journal Articles

Mechanism of quinine-dependent monoclonal antibody binding to platelet glycoprotein IIb/IIIa

Daniel W. Bougie, Julie Peterson, Mark Rasmussen, Richard H. Aster

Blood (2015) 126 (18): 2146–2152.

https://doi.org/10.1182/blood-2015-04-643148

Published: 2015

Journal Articles

Structural basis for quinine-dependent antibody binding to platelet integrin α IIb β 3

Jianghai Zhu, Jieqing Zhu, Daniel W. Bougie, Richard H. Aster, Timothy A. Springer

Blood (2015) 126 (18): 2138–2145.

https://doi.org/10.1182/blood-2015-04-639351

Published: 2015

Journal Articles

Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis

Anand Padmanabhan, Curtis G. Jones, Daniel W. Bougie, Brian R. Curtis, Janice G. McFarland, Demin Wang, Richard H. Aster

Blood (2015) 125 (1): 155–161.

https://doi.org/10.1182/blood-2014-06-580894

Published: 2015

Includes: Supplemental data

Journal Articles

Antibodies Specific For Human Neutrophil Antigen 3a (HNA-3a) Recognize Complex Epitopes On Choline Transporter Protein 2 (CTL2): Implications For HNA-3a Antibody Detection

Daniel W. Bougie, PhD, Julie A. Peterson, PhD, Adam Kanack, Brian R Curtis, PhD, D(ABMLI), Richard H. Aster, MD

Blood (2013) 122 (21): 3662.

https://doi.org/10.1182/blood.V122.21.3662.3662

Published: 2013

NARROW

A prospective, blinded study of a PF4-dependent assay for HIT diagnosis

Serologic Characterization of Antibodies in Patients Experiencing Piperacillin-Induced Immune Thrombocytopenia

Cross-Reactivity of Drug-Dependent Antibodies in Patients with Immune Thrombocytopenia Induced By Beta-Lactam Antibiotics

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

The Platelet Factor-4 (PF4)-Dependent p-Selectin Expression Assay (PEA) Is Highly Accurate for the Detection of Pathogenic HIT Antibodies: Results of a 440-Sample Prospective Blinded Study

Patients treated with oxaliplatin are at risk for thrombocytopenia caused by multiple drug-dependent antibodies

Normal plasma IgG inhibits HIT antibody–mediated platelet activation: implications for therapeutic plasma exchange

A New Assay for Platelet-Activating HIT Antibodies, the PEA, Is Specific, Reproducible and Relatively Independent of the Choice of Platelet Donor

Immunoglobulin G in Normal Plasma Inhibits HIT Antibody-Mediated Platelet Activation: Implications for Therapeutic Plasma Exchange Treatment in HIT

Autoimmune Thrombocytopenia in Mice Immunized with Allogeneic Platelets: A Model for Post-Transfusion Purpura (PTP)?

A Novel PF4-Dependent P-Selectin Expression Assay (PEA) Facilitates Early Detection of Pathogenic HIT Antibodies: Implications for Diagnosis and Treatment of HIT

Intravenous Immunoglobulin (IVIg) Is a Highly Effective Treatment for HIT: Critical Role of the IgG Fc Domain in Inhibiting HIT Antibody-Mediated Platelet Activation

Binding of Quinine-Dependent Monoclonal Antibodies to Gpiib/Iiia Appears to Involve Drug-Induced Modulation of Antibody Affinity

Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin alphaIIbbeta3

Quantitative Measurement of VWF Binding to the Platelet Integrin αIIbβ3 - Abnormalities Identified in Individuals with VWD

A Novel PF4-Dependent Platelet Activation Assay Identifies Patients Likely to Have Heparin-Induced Thrombocytopenia/Thrombosis (HIT)

Mechanism of quinine-dependent monoclonal antibody binding to platelet glycoprotein IIb/IIIa

Structural basis for quinine-dependent antibody binding to platelet integrin α IIb β 3

Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis

Antibodies Specific For Human Neutrophil Antigen 3a (HNA-3a) Recognize Complex Epitopes On Choline Transporter Protein 2 (CTL2): Implications For HNA-3a Antibody Detection

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American Society of Hematology

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American Society of Hematology

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