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Journal Articles

Simulating the Impact of Transfusion Products on Clotting Kinetics and Patient Outcome

Andrew Gosselin, Sameer Ahmad, Ashley Toussaint, Christopher Bargoud, Shane Mathew, Marie Macor, Joseph Hanna, Julie Goswami, Valerie Tutwiler

Blood (2024) 144 (Supplement 1): 5471.

https://doi.org/10.1182/blood-2024-211539

Published: 2024

Journal Articles

Understanding the Macrophage's Role in Regulating Cancer-Associated Thrombosis

Olivia D Parker, Rebecca Risman, Vaidehi Apte, Reuven Rosen, Rene Schloss, Valerie Tutwiler

Blood (2023) 142 (Supplement 1): 5356.

https://doi.org/10.1182/blood-2023-190140

Published: 2023

Journal Articles

Fibrinolysis of Contracted Blood Clots Depends on Whether Plasminogen Activator Acts from inside or Outside

Valerie Tutwiler, PhD, Alina D. Peshkova, MS, Giang Le Minh, Sergei Zaitsev, Rustem I. Litvinov, Douglas B. Cines, MD, John W. Weisel, PhD

Blood (2018) 132 (Supplement 1): 3773.

https://doi.org/10.1182/blood-2018-99-119659

Published: 2018

Journal Articles

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Jing Dai, Daria Madeeva, Vincent Hayes, Hyun Sook Ahn, Valerie Tutwiler, Gowthami M. Arepally, Douglas B. Cines, Mortimer Poncz, Lubica Rauova

Blood (2018) 132 (7): 727–734.

https://doi.org/10.1182/blood-2018-02-830737

Published: 2018

Includes: Supplemental data

Journal Articles

Impaired Contraction (Retraction) of Blood Clots Is a Possible Pathogenic Mechanism in Venous Thromboembolism

Rustem I. Litvinov, MD PhD, Alina D. Peshkova, MS, Dmitry V. Malyasyov, MD, Roman A. Bredikhin, MD PhD, Giang Le Minh, MS, Izabella A. Andrianova, MS, Valerie Tutwiler, PhD, John W. Weisel, PhD

Blood (2017) 130 (Supplement 1): 2382.

https://doi.org/10.1182/blood.V130.Suppl_1.2382.2382

Published: 2017

Journal Articles

Erythrocyte Rigidity Affects Blood Clot Contraction and Formation of Polyhedrocytes

Valerie Tutwiler, Rustem I. Litvinov, PhD, Chandrasekaran Nagaswami, J. Eric Russell, MD, Don L. Siegel, MD, PhD,, Carlos Hipolito Villa, MD PhD, Daniel Pan, PhD, Vladimir R Muzykantov, MD PhD, John W. Weisel

Blood (2016) 128 (22): 3814.

https://doi.org/10.1182/blood.V128.22.3814.3814

Published: 2016

Journal Articles

Blood Clot Contraction (Retraction) Is Impaired in Acute Ischemic Stroke

Valerie Tutwiler, Alina Peshkova, Dina Khasanova, MD, John W. Weisel, Rustem I. Litvinov, PhD

Blood (2016) 128 (22): 4998.

https://doi.org/10.1182/blood.V128.22.4998.4998

Published: 2016

Journal Articles

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Valerie Tutwiler, Daria Madeeva, Hyun Sook Ahn, Izabella Andrianova, Vincent Hayes, X. Long Zheng, Douglas B. Cines, Steven E. McKenzie, Mortimer Poncz, Lubica Rauova

Blood (2016) 127 (4): 464–472.

https://doi.org/10.1182/blood-2013-11-539262

Published: 2016

Includes: Supplemental data

Journal Articles

Kinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the blood

Valerie Tutwiler, Rustem I. Litvinov, Andrey P. Lozhkin, Alina D. Peshkova, Tatiana Lebedeva, Fazoil I. Ataullakhanov, Kara L. Spiller, Douglas B. Cines, John W. Weisel

Blood (2016) 127 (1): 149–159.

https://doi.org/10.1182/blood-2015-05-647560

Published: 2016

Includes: Supplemental data

Journal Articles

Effects of Platelets and Erythrocytes on the Dynamic Size and Mechanical Properties of Blood Clots during Contraction

Valerie Tutwiler, Rustem I. Litvinov, PhD, Tatiana Lebedeva, PhD, Fazoil I. Ataullakhanov, PhD, Douglas B. Cines, MD, John W. Weisel, PhD

Blood (2014) 124 (21): 4225.

https://doi.org/10.1182/blood.V124.21.4225.4225

Published: 2014

Journal Articles

FcγRIIA Mediates the Prothrombotic Role of Monocytes in HIT

Daria Madeeva, MD, Valerie Tutwiler, Douglas B. Cines, MD, Mortimer Poncz, MD, Lubica Rauova, MD PhD

Blood (2014) 124 (21): 575.

https://doi.org/10.1182/blood.V124.21.575.575

Published: 2014

Journal Articles

Role Of Monocyte Fcγ Receptors In The Prothrombotic State Of Heparin Induced Thrombocytopenia (HIT)

Lubica Rauova, MD, PhD, Daria Madeeva, MD, Valerie Tutwiler, Shahara Bailey, Vincent M. Hayes, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2013) 122 (21): 570.

https://doi.org/10.1182/blood.V122.21.570.570

Published: 2013

Journal Articles

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Valerie Tutwiler, Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent M. Hayes, Sergei V. Zaytsev, PhD, X. Long Zheng, MD, PhD, Douglas B. Cines, MD, Steven E. McKenzie, MD, PhD, John W. Weisel, Ph.D., Mortimer Poncz, MD, Lubica Rauova, MD, PhD

Blood (2012) 120 (21): 635.

https://doi.org/10.1182/blood.V120.21.635.635

Published: 2012

Journal Articles

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Rudy Fuentes, PhD, Hyun Sook Ahn, Vincent M. Hayes, Valerie Tutwiler, Yuhuan Wang, PhD, Daniel W. Bougie, PhD, M. Anna Kowalska, PhD, Lubica Rauova, M.D., Ph.D., Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R Muzykantov, MD PhD, Mortimer Poncz, MD, Sergei Zaitsev, PhD

Blood (2012) 120 (21): 1171.

https://doi.org/10.1182/blood.V120.21.1171.1171

Published: 2012

Journal Articles

The Two Phases of Heparin-Induced Thrombocytopenia (HIT): Early Monocyte/Tissue Factor (TF) Phase and Late Platelet Phase

Lubica Rauova, MD, PhD, Valerie Tutwiler, Hyun Sook Ahn, Vincent M. Hayes, Richard H. Aster, MD, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2012) 120 (21): 270.

https://doi.org/10.1182/blood.V120.21.270.270

Published: 2012

Journal Articles

Microfluidic and Flow Cytometric Studies Support a Role for Monocytes and Coated Platelets in the Prothrombotic State in Heparin-Induced Thrombocytopenia (HIT)

Valerie Tutwiler, Hyun Sook Ahn, Douglas B. Cines, MD, Rodney M. Camire, PhD, Mortimer Poncz, MD, Steven McKenzie, MD, PhD, Lubica Rauova, MD, PhD

Blood (2011) 118 (21): 539.

https://doi.org/10.1182/blood.V118.21.539.539

Published: 2011

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Simulating the Impact of Transfusion Products on Clotting Kinetics and Patient Outcome

Understanding the Macrophage's Role in Regulating Cancer-Associated Thrombosis

Fibrinolysis of Contracted Blood Clots Depends on Whether Plasminogen Activator Acts from inside or Outside

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Impaired Contraction (Retraction) of Blood Clots Is a Possible Pathogenic Mechanism in Venous Thromboembolism

Erythrocyte Rigidity Affects Blood Clot Contraction and Formation of Polyhedrocytes

Blood Clot Contraction (Retraction) Is Impaired in Acute Ischemic Stroke

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Kinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the blood

Effects of Platelets and Erythrocytes on the Dynamic Size and Mechanical Properties of Blood Clots during Contraction

FcγRIIA Mediates the Prothrombotic Role of Monocytes in HIT

Role Of Monocyte Fcγ Receptors In The Prothrombotic State Of Heparin Induced Thrombocytopenia (HIT)

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

The Two Phases of Heparin-Induced Thrombocytopenia (HIT): Early Monocyte/Tissue Factor (TF) Phase and Late Platelet Phase

Microfluidic and Flow Cytometric Studies Support a Role for Monocytes and Coated Platelets in the Prothrombotic State in Heparin-Induced Thrombocytopenia (HIT)

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