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Hyun Sook Ahn
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Journal Articles

Mechanistic Insights and Clinical Implications of the Thrombotic Risks of a Highly Prevalent GRK5 Variant Affecting Platelets

Yanki Yarman, Xuefei Zhao, Hyun Sook Ahn, Hannah Thomson, Meghan Roberts, Deborah L. French, Jeffrey Benovic, Timothy J. Stalker, Mortimer Poncz, Peisong Ma
Journal: Blood
Blood (2024) 144 (Supplement 1): 424.
https://doi.org/10.1182/blood-2024-205760
Published: 2024
Journal Articles

RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects

Kiwon Lee, Hyun Sook Ahn, Brian Estevez, Mortimer Poncz
Journal: Blood
Blood (2023) 141 (3): 260–270.
https://doi.org/10.1182/blood.2022017561
Published: 2023
Includes: Supplemental data
Journal Articles

Dynamic intercellular redistribution of HIT antigen modulates heparin-induced thrombocytopenia

Jing Dai, Daria Madeeva, Vincent Hayes, Hyun Sook Ahn, Valerie Tutwiler, Gowthami M. Arepally, Douglas B. Cines, Mortimer Poncz, Lubica Rauova
Journal: Blood
Blood (2018) 132 (7): 727–734.
https://doi.org/10.1182/blood-2018-02-830737
Published: 2018
Includes: Supplemental data
Journal Articles

Platelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia

Valerie Tutwiler, Daria Madeeva, Hyun Sook Ahn, Izabella Andrianova, Vincent Hayes, X. Long Zheng, Douglas B. Cines, Steven E. McKenzie, Mortimer Poncz, Lubica Rauova
Journal: Blood
Blood (2016) 127 (4): 464–472.
https://doi.org/10.1182/blood-2013-11-539262
Published: 2016
Includes: Supplemental data
Journal Articles

A Human-Specific, Platelet-Targeted, Thrombin-Activatable Urokinase (PLT/uPA-T) Demonstrates Selective Thromboprophylactic Properties in Two in Vivo Models

Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent Hayes, Douglas B. Cines, MD, Vladimir R Muzykantov, MDPhD, Sergei V. Zaytsev, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2014) 124 (21): 579.
https://doi.org/10.1182/blood.V124.21.579.579
Published: 2014
Journal Articles

The Two Phases of Heparin-Induced Thrombocytopenia (HIT): Early Monocyte/Tissue Factor (TF) Phase and Late Platelet Phase

Lubica Rauova, MD, PhD, Valerie Tutwiler, Hyun Sook Ahn, Vincent M. Hayes, Richard H. Aster, MD, Douglas B. Cines, MD, Mortimer Poncz, MD
Journal: Blood
Blood (2012) 120 (21): 270.
https://doi.org/10.1182/blood.V120.21.270.270
Published: 2012
Journal Articles

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Valerie Tutwiler, Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent M. Hayes, Sergei V. Zaytsev, PhD, X. Long Zheng, MD, PhD, Douglas B. Cines, MD, Steven E. McKenzie, MD, PhD, John W. Weisel, Ph.D., Mortimer Poncz, MD, Lubica Rauova, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 635.
https://doi.org/10.1182/blood.V120.21.635.635
Published: 2012
Journal Articles

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Rudy Fuentes, PhD, Hyun Sook Ahn, Vincent M. Hayes, Valerie Tutwiler, Yuhuan Wang, PhD, Daniel W. Bougie, PhD, M. Anna Kowalska, PhD, Lubica Rauova, M.D., Ph.D., Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R Muzykantov, MD PhD, Mortimer Poncz, MD, Sergei Zaitsev, PhD
Journal: Blood
Blood (2012) 120 (21): 1171.
https://doi.org/10.1182/blood.V120.21.1171.1171
Published: 2012
Journal Articles

Microfluidic and Flow Cytometric Studies Support a Role for Monocytes and Coated Platelets in the Prothrombotic State in Heparin-Induced Thrombocytopenia (HIT)

Valerie Tutwiler, Hyun Sook Ahn, Douglas B. Cines, MD, Rodney M. Camire, PhD, Mortimer Poncz, MD, Steven McKenzie, MD, PhD, Lubica Rauova, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 539.
https://doi.org/10.1182/blood.V118.21.539.539
Published: 2011