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Journal Articles

Prophylactic Administration of HPA-1a-Specific Antibody RLYB212 Safely Prevents Fetal/Neonatal Alloimmune Thrombocytopenia in Pregnant Mice

Huiying Zhi, Douglas Sheridan, Peter J. Newman, Debra K. Newman

Blood (2024) 144 (Supplement 1): 1185.

https://doi.org/10.1182/blood-2024-208433

Published: 2024

Journal Articles

Fetal Maternal Hemorrhage As a Trigger for Fetal/Neonatal Alloimmune Thrombocytopenia: Evidence from a Murine Model

Huiying Zhi, Debra K. Newman, Peter J. Newman

Blood (2023) 142 (Supplement 1): 2664.

https://doi.org/10.1182/blood-2023-178032

Published: 2023

Journal Articles

Prophylactic administration of HPA-1a–specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice

Huiying Zhi, Douglas Sheridan, Debra K. Newman, Peter J. Newman

Blood (2022) 140 (20): 2146–2153.

https://doi.org/10.1182/blood.2022015666

Published: 2022

Includes: Supplemental data

Journal Articles

CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Huiying Zhi, Guoping Fu, Renren Wen, Demin Wang, Peter J. Newman, Debra K. Newman

Blood (2022) 140 (Supplement 1): 2828.

https://doi.org/10.1182/blood-2022-169883

Published: 2022

Journal Articles

Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in a Preclinical Model By Monoclonal Anti-HPA-1a Antibody Prophylaxis: Structural and Functional Properties of Antibody Variant Isoforms

Trude Victoria Mørtberg, Huiying Zhi, Gestur Vidarsson, Stian Foss, Terje E Michaelsen, Bjørn Skogen, Tor Brynjar Stuge, Jan Terje Andersen, Peter J. Newman, Maria Therese Ahlen

Blood (2021) 138 (Supplement 1): 1011.

https://doi.org/10.1182/blood-2021-149196

Published: 2021

Journal Articles

Prophylactic Administration of Antibodies Specific for the HPA-1a Epitope Prevents Alloimmunization and Platelet Destruction in a Murine Model of Fetal Neonatal Alloimmune Thrombocytopenia

Huiying Zhi, Douglas Sheridan, Peter J. Newman

Blood (2021) 138 (Supplement 1): 3153.

https://doi.org/10.1182/blood-2021-148557

Published: 2021

Journal Articles

An Authentic Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Huiying Zhi, PhD, Maria Therese Ahlen, PhD, Trude Rasmussen, Bjørn Skogen, MD, Peter J. Newman, PhD

Blood (2019) 134 (Supplement_1): 97.

https://doi.org/10.1182/blood-2019-130573

Published: 2019

Journal Articles

Atomic-Level Dissection of the Polyclonal Immune Response to the Human Platelet Alloantigen, HPA-1a (Pl A1 )

Huiying Zhi, PhD, Maria Therese Ahlen, PhD, Aye Myat Myat Thinn, PhD, Hartmut Weiler, PhD, Brian R. Curtis, PhD, Bjorn Skogen, MD, Jieqing Zhu, PhD, Peter Newman, PhD

Blood (2018) 132 (Supplement 1): 1258.

https://doi.org/10.1182/blood-2018-99-111327

Published: 2018

Journal Articles

Recreation of Fetal Neonatal Alloimmune Thrombocytopenia in CRISPR/Cas9 Gene-Edited Mice Expressing the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, PhD, Maria Therese Ahlen, PhD, Bjørn Skogen, PhD, Peter Newman, PhD

Blood (2017) 130 (Supplement 1): 764.

https://doi.org/10.1182/blood.V130.Suppl_1.764.764

Published: 2017

Journal Articles

CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes

Nanyan Zhang, Huiying Zhi, Brian R. Curtis, Sridhar Rao, Chintan Jobaliya, Mortimer Poncz, Deborah L. French, Peter J. Newman

Blood (2016) 127 (6): 675–680.

https://doi.org/10.1182/blood-2015-10-675751

Published: 2016

Includes: Supplemental data

Journal Articles

Involvement of the EGF Domain in the Formation of the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, MD PhD, Panida Lertkiatmongkol, Brian R Curtis, PhD D(ABMLI), Peter J. Newman, PhD

Blood (2015) 126 (23): 2340.

https://doi.org/10.1182/blood.V126.23.2340.2340

Published: 2015

Journal Articles

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Huiying Zhi, MD PhD, Nanyan Zhang, MD PhD, Jamie Foeckler, Shawn Kalloway, PhD, Sridhar Rao, MD PhD, Brian R Curtis, PhD D(ABMLI), Hartmut Weiler, PhD, Peter J. Newman, PhD

Blood (2015) 126 (23): 2341.

https://doi.org/10.1182/blood.V126.23.2341.2341

Published: 2015

Journal Articles

Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes

Nanyan Zhang, MD PhD, Huiying Zhi, MD PhD, Sridhar Rao, Peter J. Newman, PhD

Blood (2014) 124 (21): 573.

https://doi.org/10.1182/blood.V124.21.573.573

Published: 2014

Journal Articles

An Unexpected Role For αIIbβ3 In Immune Complex Disorders

Huiying Zhi, MD, PhD, Nannan Wu, Jing Dai, Juan Fang, MD, Pu Liu, Junling Liu, Hu Hu, PhD, Jieqing Zhu, PhD, Debra K. Newman, PhD, Peter J. Newman, PhD, Cunji Gao, MD, PhD

Blood (2013) 122 (21): 2293.

https://doi.org/10.1182/blood.V122.21.2293.2293

Published: 2013

Journal Articles

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

Huiying Zhi, Lubica Rauova, Vincent Hayes, Cunji Gao, Brian Boylan, Debra K. Newman, Steven E. McKenzie, Brian C. Cooley, Mortimer Poncz, Peter J. Newman

Blood (2013) 121 (10): 1858–1867.

https://doi.org/10.1182/blood-2012-07-443325

Published: 2013

Includes: Supplemental data

Journal Articles

FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo

Huiying Zhi, PhD, Lubica Rauova, MD, PhD, Vincent M Hayes, Jimmy Crockett, BS, Cunji Gao, MD, PhD, Brian Boylan, Debra K. Newman, PhD, Steven McKenzie, MD, PhD, Brian C. Cooley, Ph.D., Mortimer Poncz, MD, Peter J. Newman, PhD

Blood (2011) 118 (21): 191.

https://doi.org/10.1182/blood.V118.21.191.191

Published: 2011

Journal Articles

Disaggregation Signals Initiated by Ligand Binding and Platelet Aggregation

Cunji Gao, MD, PhD, Juan Fang, MD, Huiying Zhi, PhD, David A. Wilcox, PhD, Peter J. Newman, PhD

Blood (2011) 118 (21): 2196.

https://doi.org/10.1182/blood.V118.21.2196.2196

Published: 2011

NARROW

Prophylactic Administration of HPA-1a-Specific Antibody RLYB212 Safely Prevents Fetal/Neonatal Alloimmune Thrombocytopenia in Pregnant Mice

Fetal Maternal Hemorrhage As a Trigger for Fetal/Neonatal Alloimmune Thrombocytopenia: Evidence from a Murine Model

Prophylactic administration of HPA-1a–specific antibodies prevents fetal/neonatal alloimmune thrombocytopenia in mice

CD4+ T Cells Are Required for Production of Disease-Causing Antibodies in an Alloantigen-Specific Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in a Preclinical Model By Monoclonal Anti-HPA-1a Antibody Prophylaxis: Structural and Functional Properties of Antibody Variant Isoforms

Prophylactic Administration of Antibodies Specific for the HPA-1a Epitope Prevents Alloimmunization and Platelet Destruction in a Murine Model of Fetal Neonatal Alloimmune Thrombocytopenia

An Authentic Murine Model of Fetal/Neonatal Alloimmune Thrombocytopenia

Atomic-Level Dissection of the Polyclonal Immune Response to the Human Platelet Alloantigen, HPA-1a (Pl A1 )

Recreation of Fetal Neonatal Alloimmune Thrombocytopenia in CRISPR/Cas9 Gene-Edited Mice Expressing the Human Platelet Alloantigen, HPA-1a

CRISPR/Cas9-mediated conversion of human platelet alloantigen allotypes

Involvement of the EGF Domain in the Formation of the Human Platelet Alloantigen, HPA-1a

Crispr/Cas9-Mediated Generation of Mouse Platelets Expressing the Human Platelet Alloantigen, HPA-1a

Designer Platelets: Crispr/Cas-Mediated Conversion of Human Platelet Alloantigen Allotypes

An Unexpected Role For αIIbβ3 In Immune Complex Disorders

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo

Disaggregation Signals Initiated by Ligand Binding and Platelet Aggregation

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American Society of Hematology

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American Society of Hematology

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