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Journal Articles

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Junsong Zhou, Yi Wu, Fengwu Chen, Lu Wang, Lubica Rauova, Vincent M. Hayes, Mortimer Poncz, Hong Li, Tong Liu, Junling Liu, David W. Essex

Blood (2017) 130 (6): 817–828.

https://doi.org/10.1182/blood-2016-12-755587

Published: 2017

Includes: Supplemental data

Journal Articles

Platelet Release from Infused CD34 + -Derived Human Megakaryocytes: Lessons from a Natural-Occurring Platelet Bioreactor

Ian Johnston, BS, Vincent M Hayes, BS, Jing Dai, MD PhD, Danuta Jadwiga Jarocha, PhD, Paul Kubes, PhD, Mortimer Poncz, MD, Lubica Rauova, MD PhD

Blood (2016) 128 (22): 1375.

https://doi.org/10.1182/blood.V128.22.1375.1375

Published: 2016

Journal Articles

Enhancing Functional Platelet Release In Vivo from in Vitro-Grown Megakaryocytes Using the Protein Kinase Inhibitor SU6656

Danuta Jadwiga Jarocha, PhD, Karen K Vo, BS, Randolph B Lyde, Jr., BS, Vincent M Hayes, BS, Mortimer Poncz

Blood (2016) 128 (22): 1029.

https://doi.org/10.1182/blood.V128.22.1029.1029

Published: 2016

Journal Articles

The Second CGHC Motif of Protein Disulfide Isomerase Mediates Thrombosis

Junsong Zhou, BS, Yi Wu, Lu Wang, BS, Lubica Rauova, MD PhD, Vincent M Hayes, BS, Mortimer Poncz, MD, David W Essex, MD

Blood (2015) 126 (23): 1032.

https://doi.org/10.1182/blood.V126.23.1032.1032

Published: 2015

Journal Articles

Membrane Remodeling By Pathogenic Antibodies Underlies Monocyte Activation in Heparin-Induced Thrombocytopenia

Izabella Andrianova, Vincent M Hayes, BS, Daria Madeeva, MD, Rustem I. Litvinov, PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, John W. Weisel, PhD, Lubica Rauova, MD PhD

Blood (2015) 126 (23): 2244.

https://doi.org/10.1182/blood.V126.23.2244.2244

Published: 2015

Journal Articles

A Targeted Photochemical Microfluidic Vascular Injury Model for in Vitro Thrombosis Studies: Usage in Heparin-Induced Thrombocytopenia (HIT)

Ian Johnston, BS, Vincent M Hayes, BS, Douglas B. Cines, Mortimer Poncz, MD

Blood (2015) 126 (23): 212.

https://doi.org/10.1182/blood.V126.23.212.212

Published: 2015

Journal Articles

Imaging Morphologic Changes On Platelet and Monocyte Surfaces In Heparin-Induced Thrombocytopenia (HIT)

Lubica Rauova, MD, PhD, Yanjun Zhang, PhD, Vincent M. Hayes, Chandrasekaran Nagaswami, Douglas B. Cines, MD, Jing-fei Dong, MD, PhD, Mortimer Poncz, MD, John W. Weisel, PhD.

Blood (2013) 122 (21): 3533.

https://doi.org/10.1182/blood.V122.21.3533.3533

Published: 2013

Journal Articles

Polyhedrocytes: Compressed Polyhedral Erythrocytes In Contracted Blood Clots and Thrombi

John W. Weisel, PhD, Tatiana Lebedeva, M.D. Ph.D., Chandrasekaran Nagaswami, Vincent M. Hayes, Walter Massefski, Ph.D., Rustem I. Litvinov, Ph.D., Lubica Rauova, MD, PhD, Thomas J. Lowery, Ph.D., Douglas B. Cines, MD

Blood (2013) 122 (21): 452.

https://doi.org/10.1182/blood.V122.21.452.452

Published: 2013

Journal Articles

Insights Into Thrombopoiesis From Infused Human Megakaryocytes Into Mice

Yuhuan Wang, PhD, Vincent M. Hayes, Prasuna Paluru, Stella T. Chou, MD, Deborah L. French, Mortimer Poncz, MD

Blood (2013) 122 (21): 1165.

https://doi.org/10.1182/blood.V122.21.1165.1165

Published: 2013

Journal Articles

Role Of Monocyte Fcγ Receptors In The Prothrombotic State Of Heparin Induced Thrombocytopenia (HIT)

Lubica Rauova, MD, PhD, Daria Madeeva, MD, Valerie Tutwiler, Shahara Bailey, Vincent M. Hayes, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2013) 122 (21): 570.

https://doi.org/10.1182/blood.V122.21.570.570

Published: 2013

Journal Articles

Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs)

Yuhuan Wang, PhD, Vincent M. Hayes, Lin Lu, Ph.D, Xiaoji Chen, Rudy Fuentes, PhD, Qiang Jeremy Wen, MD, PhD, Stella T Chou, MD, John Crispino, PhD, Patrick Paddison, PhD, Deborah L. French, PhD, Beverly Torok-Storb, PhD, Mortimer Poncz, MD

Blood (2012) 120 (21): 3450.

https://doi.org/10.1182/blood.V120.21.3450.3450

Published: 2012

Journal Articles

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Valerie Tutwiler, Hyun Sook Ahn, Rudy Fuentes, PhD, Vincent M. Hayes, Sergei V. Zaytsev, PhD, X. Long Zheng, MD, PhD, Douglas B. Cines, MD, Steven E. McKenzie, MD, PhD, John W. Weisel, Ph.D., Mortimer Poncz, MD, Lubica Rauova, MD, PhD

Blood (2012) 120 (21): 635.

https://doi.org/10.1182/blood.V120.21.635.635

Published: 2012

Journal Articles

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Rudy Fuentes, PhD, Hyun Sook Ahn, Vincent M. Hayes, Valerie Tutwiler, Yuhuan Wang, PhD, Daniel W. Bougie, PhD, M. Anna Kowalska, PhD, Lubica Rauova, M.D., Ph.D., Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R Muzykantov, MD PhD, Mortimer Poncz, MD, Sergei Zaitsev, PhD

Blood (2012) 120 (21): 1171.

https://doi.org/10.1182/blood.V120.21.1171.1171

Published: 2012

Journal Articles

The Two Phases of Heparin-Induced Thrombocytopenia (HIT): Early Monocyte/Tissue Factor (TF) Phase and Late Platelet Phase

Lubica Rauova, MD, PhD, Valerie Tutwiler, Hyun Sook Ahn, Vincent M. Hayes, Richard H. Aster, MD, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2012) 120 (21): 270.

https://doi.org/10.1182/blood.V120.21.270.270

Published: 2012

Journal Articles

“Rolling Recruitment” of Endothelial Cell (EC) Activation in the Prothrombotic Nature of Heparin-Induced Thrombocytopenia (HIT)

Vincent M Hayes, Douglas B. Cines, MD, Mortimer Poncz, MD, Lubica Rauova, MD, PhD

Blood (2011) 118 (21): 536.

https://doi.org/10.1182/blood.V118.21.536.536

Published: 2011

Journal Articles

FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo

Huiying Zhi, PhD, Lubica Rauova, MD, PhD, Vincent M Hayes, Jimmy Crockett, BS, Cunji Gao, MD, PhD, Brian Boylan, Debra K. Newman, PhD, Steven McKenzie, MD, PhD, Brian C. Cooley, Ph.D., Mortimer Poncz, MD, Peter J. Newman, PhD

Blood (2011) 118 (21): 191.

https://doi.org/10.1182/blood.V118.21.191.191

Published: 2011

Journal Articles

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

Lubica Rauova, Jessica D. Hirsch, Teshell K. Greene, Li Zhai, Vincent M. Hayes, M. Anna Kowalska, Douglas B. Cines, Mortimer Poncz

Blood (2010) 116 (23): 5021–5031.

https://doi.org/10.1182/blood-2010-03-276964

Published: 2010

Includes: Multimedia, Supplemental data

NARROW

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Platelet Release from Infused CD34 + -Derived Human Megakaryocytes: Lessons from a Natural-Occurring Platelet Bioreactor

Enhancing Functional Platelet Release In Vivo from in Vitro-Grown Megakaryocytes Using the Protein Kinase Inhibitor SU6656

The Second CGHC Motif of Protein Disulfide Isomerase Mediates Thrombosis

Membrane Remodeling By Pathogenic Antibodies Underlies Monocyte Activation in Heparin-Induced Thrombocytopenia

A Targeted Photochemical Microfluidic Vascular Injury Model for in Vitro Thrombosis Studies: Usage in Heparin-Induced Thrombocytopenia (HIT)

Imaging Morphologic Changes On Platelet and Monocyte Surfaces In Heparin-Induced Thrombocytopenia (HIT)

Polyhedrocytes: Compressed Polyhedral Erythrocytes In Contracted Blood Clots and Thrombi

Insights Into Thrombopoiesis From Infused Human Megakaryocytes Into Mice

Role Of Monocyte Fcγ Receptors In The Prothrombotic State Of Heparin Induced Thrombocytopenia (HIT)

Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs)

Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

The Two Phases of Heparin-Induced Thrombocytopenia (HIT): Early Monocyte/Tissue Factor (TF) Phase and Late Platelet Phase

“Rolling Recruitment” of Endothelial Cell (EC) Activation in the Prothrombotic Nature of Heparin-Induced Thrombocytopenia (HIT)

FcγRIIa Enhances Thrombus Growth in Vitro and in Vivo

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

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