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Spencer K. Sullivan
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Journal Articles

Health-Related Quality of Life in Adults with Hemophilia B after Receiving Gene Therapy with Fidanacogene Elaparvovec

Sylvia von Mackensen, Jonathan M. Ducore, Lindsey A. George, Adam Giermasz, Catherine McGuinn, John E. J. Rasko, Ben J Samelson-Jones, Spencer K. Sullivan, Jerome M. Teitel, Amit Chhabra, Annie F. Fang, Amanda O'Brien, Frank Plonski, Jeremy Rupon, Lynne Smith, Ian Winburn
Journal: Blood
Blood (2023) 142 (Supplement 1): 3628.
https://doi.org/10.1182/blood-2023-179431
Published: 2023
Journal Articles

Follow-up of More Than 5 Years in a Cohort of Patients with Hemophilia B Treated with Fidanacogene Elaparvovec Adeno-Associated Virus Gene Therapy

Ben J. Samelson-Jones, Spencer K. Sullivan, John E.J. Rasko, Adam Giermasz, Lindsey A. George, Jonathan M. Ducore, Jerome M. Teitel, Catherine E. McGuinn, Amanda O'Brien, Ian Winburn, Lynne M Smith, Amit Chhabra, Jeremy Rupon
Journal: Blood
Blood (2021) 138 (Supplement 1): 3975.
https://doi.org/10.1182/blood-2021-150541
Published: 2021
Journal Articles

Efficacy and Safety in 15 Hemophilia B Patients Treated with the AAV Gene Therapy Vector Fidanacogene Elaparvovec and Followed for at Least 1 Year

Lindsey A. George, MD, Spencer K. Sullivan, MD, John E.J. Rasko, MBBS, PhD, Adam Giermasz, MD PhD, Benjamin J. Samelson-Jones, MD PhD, Jonathan M. Ducore, MD MPH, Jerome M. Teitel, MD FRCPC, Catherine E. McGuinn, MD, Alexa R. Runowski, MS, Fraser Wright, PhD, Xavier M. Anguela, PhD, Katherine A. High, MD, Denis Rybin, PhD, John E. Murphy, PhD, Jeremy Rupon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3347.
https://doi.org/10.1182/blood-2019-124091
Published: 2019
Journal Articles

A Phase 1/2 Trial of Investigational Spk-8011 in Hemophilia a Demonstrates Durable Expression and Prevention of Bleeds

Katherine A. High, MD, Lindsey A. George, MD, M. Elaine Eyster, MD, Spencer K. Sullivan, MD, Margaret V. Ragni, MD MPH, Stacy E. Croteau, MD, Ben J. Samelson-Jones, MD PhD, Matthew Evans, MD, Marcelyne Joseney-Antoine, Amy Macdougall, BSN, Judith Kadosh, BSN RN, Alexa R. Runoski, MS, Cynthia Campbell-Baird, Kayla Douglas, Summer Tompkins, Howard Hait, Linda B. Couto, PhD, Ashlyn Eaton Bassiri, PhD, Leonard A. Valentino, MD, Marcus E. Carr, MD PhD, Daniel J Hui, PhD BS, Katie Wachtel, MS, Daniel Takefman, Federico Mingozzi, PhD, Xavier M. Anguela, PhD, Kathleen B Reape, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 487.
https://doi.org/10.1182/blood-2018-99-115495
Published: 2018
Journal Articles

Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B - 1 Year Follow up and Impact of Baseline Characteristics on Transgene-Derived Factor IX Activity and Persistence

Lindsey A. George, MD, Spencer K. Sullivan, MD, Adam Giermasz, MD, Ben J. Samelson-Jones, MD PhD, Jonathan M. Ducore, MD, Jerome M. Teitel, MD FRCPC, Adam Cuker, MD MS, Sylvia Von Mackensen, PhD, Suvankar Majumdar, MD, Catherine E. McGuinn, MD, Alexa R. Runoski, MS, Fraser Wright, PhD, Sue Dasen, MS, Kimberly Barber, Yifeng Chen, MD, Daniel J. Hui, PhD, Ruchi Patel, Yun Liu, PhD, Katie Wachtel, MS, Dan Takefman, Linda B. Couto, PhD, Kathleen Z. Reape, Marcus E. Carr, MD PhD, Xavier M. Anguela, PhD, Katherine A. High, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 601.
https://doi.org/10.1182/blood.V130.Suppl_1.601.601
Published: 2017
Journal Articles

Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Achieves Sustained Factor IX with Minimal Immune Response

Daniel J Hui, PhD BS, Yun Liu, PhD, Ruchi Patel, Yifeng Chen, MD, Lindsey A. George, MD, Spencer K. Sullivan, MD, Adam Giermasz, MD, John Rasko, MBBS, PhD, Ben J. Samelson-Jones, MD PhD, Jonathan M. Ducore, MD, Sue Dasen, MS, Marcus E. Carr, MD PhD, Xavier M. Anguela, PhD, Katherine A. High, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2056.
https://doi.org/10.1182/blood.V130.Suppl_1.2056.2056
Published: 2017
Journal Articles

FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology

Karen K. Vo, Danuta J. Jarocha, Randolph B. Lyde, Vincent Hayes, Christopher S. Thom, Spencer K. Sullivan, Deborah L. French, Mortimer Poncz
Journal: Blood
Blood (2017) 129 (26): 3486–3494.
https://doi.org/10.1182/blood-2017-02-770958
Published: 2017
Includes: Supplemental data
Journal Articles

Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Achieves Sustained Mean Factor IX Activity Levels of >30% without Immunosuppression

Lindsey A. George, MD, Spencer K. Sullivan, MD, Adam Giermasz, MD, PhD, Jonathan M. Ducore, Jerome M. Teitel, MD, Adam Cuker, MD MS, Lisa M. Sullivan, MD, Suvankar Majumdar, MD, Catherine E. McGuinn, MD, Aline M. Galvao, M.S., B.S.N.-R.N., Alvin Y. Luk, PhD, M.B.A., J. Fraser Wright, PhD, Yifeng Chen, MD, Daniel J. Hui, PhD, Katie Wachtel, M.S., Teresa Urich, B.S., Daniel Takefman, PhD, Linda B. Couto, PhD, Marcus E. Carr, MD, PhD, Xavier M. Anguela, PhD, Katherine A. High, MD
Journal: Blood
Blood (2016) 128 (22): 3.
https://doi.org/10.1182/blood.V128.22.3.3
Published: 2016
Journal Articles

Infusion of Coagulation Factor VIII-Containing Induced Pluripotent Stem Cell (iPSC)-Derived Megakaryocytes (iMks) Shows Potential As Hemophilia a Treatment

Randolph B Lyde, Jr., BS, Hyunsook Ahn, Karen K Vo, BS, Danuta Jadwiga Jarocha, PhD, Li Zhai, BS, Spencer K. Sullivan, MD, Valder R Arruda, MD PhD, Denise E. Sabatino, PhD, Rodney M. Camire, PhD, Deborah French, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2016) 128 (22): 2559.
https://doi.org/10.1182/blood.V128.22.2559.2559
Published: 2016
Journal Articles

Fli1 Expression Level Affects Megakaryopoiesis and Thrombopoiesis: More Is Not Always a Bad Thing

Karen K Vo, BS, Danuta Jadwiga Jarocha, PhD, Randolph B Lyde, Jr., BS, Spencer K. Sullivan, MD, Deborah French, PhD, Mortimer Poncz, MD
Journal: Blood
Blood (2016) 128 (22): 3876.
https://doi.org/10.1182/blood.V128.22.3876.3876
Published: 2016
Journal Articles

Comparative analysis of human ex vivo–generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale

Yuhuan Wang, Vincent Hayes, Danuta Jarocha, Xiuli Sim, Dawn C. Harper, Rudy Fuentes, Spencer K. Sullivan, Paul Gadue, Stella T. Chou, Beverly J. Torok-Storb, Michael S. Marks, Deborah L. French, Mortimer Poncz
Journal: Blood
Blood (2015) 125 (23): 3627–3636.
https://doi.org/10.1182/blood-2014-08-593053
Published: 2015
Includes: Supplemental data
Journal Articles

A(nother) day in the life of neonatal platelets

Spencer K. Sullivan, Mortimer Poncz
Journal: Blood
Blood (2014) 123 (22): 3372–3373.
https://doi.org/10.1182/blood-2014-03-562132
Published: 2014
Journal Articles

High-level transgene expression in induced pluripotent stem cell–derived megakaryocytes: correction of Glanzmann thrombasthenia

Brief Report
Spencer K. Sullivan, Jason A. Mills, Sevasti B. Koukouritaki, Karen K. Vo, Randolph B. Lyde, Prasuna Paluru, Guoha Zhao, Li Zhai, Lisa M. Sullivan, Yuhuan Wang, Siddharth Kishore, Eyad Z. Gharaibeh, Michele P. Lambert, David A. Wilcox, Deborah L. French, Mortimer Poncz, Paul Gadue
Journal: Blood
Blood (2014) 123 (5): 753–757.
https://doi.org/10.1182/blood-2013-10-530725
Published: 2014
Includes: Supplemental data
Journal Articles

Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines

Brief Report
Jason A. Mills, Kai Wang, Prasuna Paluru, Lei Ying, Lin Lu, Aline M. Galvão, Dongbin Xu, Yu Yao, Spencer K. Sullivan, Lisa M. Sullivan, Helen Mac, Amel Omari, Jyh-Chang Jean, Steve Shen, Adam Gower, Avi Spira, Gustavo Mostoslavsky, Darrell N. Kotton, Deborah L. French, Mitchell J. Weiss, Paul Gadue
Journal: Blood
Blood (2013) 122 (12): 2047–2051.
https://doi.org/10.1182/blood-2013-02-484444
Published: 2013
Includes: Supplemental data
Journal Articles

Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia

Brief Report
Shilpa Gandre-Babbe, Prasuna Paluru, Chiaka Aribeana, Stella T. Chou, Silvia Bresolin, Lin Lu, Spencer K. Sullivan, Sarah K. Tasian, Julie Weng, Helene Favre, John K. Choi, Deborah L. French, Mignon L. Loh, Mitchell J. Weiss
Journal: Blood
Blood (2013) 121 (24): 4925–4929.
https://doi.org/10.1182/blood-2013-01-478412
Published: 2013
Includes: Supplemental data
Journal Articles

Challenges and promises for the development of donor-independent platelet transfusions

Michele P. Lambert, Spencer K. Sullivan, Rudy Fuentes, Deborah L. French, Mortimer Poncz
Journal: Blood
Blood (2013) 121 (17): 3319–3324.
https://doi.org/10.1182/blood-2012-09-455428
Published: 2013
Journal Articles

Tissue-Specific Transgene Expression in Induced Pluripotent Stem (iPS) Cell-Derived Megakaryocytes: Correction of Glanzmann Thrombasthenia (GT)

Spencer K. Sullivan, MD, Jason A. Mills, PhD, Li Zhai, MD, Prasuna Paluru, MS, Karen Vo, Michele Lambert, MD, Sevasti B. Koukouritaki, PhD, Juan Fang, MD, David A. Wilcox, PhD, Deborah L. French, PhD, Mortimer Poncz, MD, Paul Gadue, PhD
Journal: Blood
Blood (2012) 120 (21): 387.
https://doi.org/10.1182/blood.V120.21.387.387
Published: 2012