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Journal Articles

Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation

Sergei Zaitsev, Dirk Spitzer, Juan-Carlos Murciano, Bi-Sen Ding, Samira Tliba, M. Anna Kowalska, Oscar A. Marcos-Contreras, Alice Kuo, Victoria Stepanova, John P. Atkinson, Mortimer Poncz, Douglas B. Cines, Vladimir R. Muzykantov
Journal: Blood
Blood (2010) 115 (25): 5241–5248.
https://doi.org/10.1182/blood-2010-01-261610
Published: 2010
Includes: Supplemental data
Journal Articles

Nuclear translocation of urokinase-type plasminogen activator

Victoria Stepanova, Tatiana Lebedeva, Alice Kuo, Serge Yarovoi, Sergei Tkachuk, Sergei Zaitsev, Khalil Bdeir, Inna Dumler, Michael S. Marks, Yelena Parfyonova, Vsevolod A. Tkachuk, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2008) 112 (1): 100–110.
https://doi.org/10.1182/blood-2007-07-104455
Published: 2008
Includes: Multimedia, Supplemental data
Journal Articles

Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature

Bi-Sen Ding, Claudia Gottstein, Andrea Grunow, Alice Kuo, Kumkum Ganguly, Steven M. Albelda, Douglas B. Cines, Vladimir R. Muzykantov
Journal: Blood
Blood (2005) 106 (13): 4191–4198.
https://doi.org/10.1182/blood-2005-05-2002
Published: 2005
Journal Articles

Interaction of High Molecular Weight Kininogen with Endothelial Cell Receptors suPAR, gC1qR and Cytokeratin 1 by Surface Plasmon Resonance (BiaCore).

Ricardo G. Espinola, Robin A. Pixley, Berhane Ghebrehiwet, Kusumam Joseph, Alice Kuo, Douglas B. Cines, Robert W. Colman
Journal: Blood
Blood (2005) 106 (11): 2666.
https://doi.org/10.1182/blood.V106.11.2666.2666
Published: 2005
Journal Articles

Crystal Structure of the Interaction of Human Urokinase Plasminogen Activitor with Its Receptor.

Qing Huai, PhD, Andrew P. Mazar, Ph.D, Graham Parry, Ph.D, Alice Kuo, Douglas B. Cines, MD, Yongdong Li, Cai Yuan, Chuanbing Bian, Liqing Chen, Ph.D, Bruce Furie, MD, Barbara C. Furie, Ph.D, Mingdong Huang, Ph.D
Journal: Blood
Blood (2005) 106 (11): 683.
https://doi.org/10.1182/blood.V106.11.683.683
Published: 2005
Journal Articles

Regulation of the single-chain urokinase–urokinase receptor complex activity by plasminogen and fibrin: novel mechanism of fibrin specificity

Abd Al-Roof Higazi, Feras Ajawi, Sa'ed Akkawi, Edna Hess, Alice Kuo, Douglas B. Cines
Journal: Blood
Blood (2005) 105 (3): 1021–1028.
https://doi.org/10.1182/blood-2004-03-0995
Published: 2005
Journal Articles

The kringle stabilizes urokinase binding to the urokinase receptor

Khalil Bdeir, Alice Kuo, Bruce S. Sachais, Ann H. Rux, Yasmina Bdeir, Andrew Mazar, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (2003) 102 (10): 3600–3608.
https://doi.org/10.1182/blood-2003-03-0949
Published: 2003
Journal Articles

Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets

Dubravka Kufrin, Don E. Eslin, Khalil Bdeir, Juan-Carlos Murciano, Alice Kuo, M. Anna Kowalska, Jay L. Degen, Bruce S. Sachais, Douglas B. Cines, Mortimer Poncz
Journal: Blood
Blood (2003) 102 (3): 926–933.
https://doi.org/10.1182/blood-2003-01-0054
Published: 2003
Journal Articles

Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic itinerary, resulting in retention of low-density lipoprotein on the cell surface

Bruce S. Sachais, Alice Kuo, Taher Nassar, Jeanelle Morgan, Katalin Kariko, Kevin Jon Williams, Michael Feldman, Michael Aviram, Neelima Shah, Leonard Jarett, Mortimer Poncz, Douglas B. Cines, Abd Al-Roof Higazi
Journal: Blood
Blood (2002) 99 (10): 3613–3622.
https://doi.org/10.1182/blood.V99.10.3613
Published: 2002
Journal Articles

Defensin Promotes the Binding of Lipoprotein(a) to Vascular Matrix

Khalil Bdeir, William Cane, Gabriela Canziani, Irwin Chaiken, John Weisel, Marlys L. Koschinsky, Richard M. Lawn, Peter G. Bannerman, Bruce S. Sachais, Alice Kuo, Mark A. Hancock, John Tomaszewski, P.N. Raghunath, Tomas Ganz, Abd Al-Roof Higazi, Douglas B. Cines
Journal: Blood
Blood (1999) 94 (6): 2007–2019.
https://doi.org/10.1182/blood.V94.6.2007
Published: 1999
Journal Articles

Lysis of Plasma Clots by Urokinase-Soluble Urokinase Receptor Complexes

Abd Al-Roof Higazi, Khalil Bdeir, Edna Hiss, Shira Arad, Alice Kuo, Iyad Barghouti, Douglas B. Cines
Journal: Blood
Blood (1998) 92 (6): 2075–2083.
https://doi.org/10.1182/blood.V92.6.2075
Published: 1998
Journal Articles

Tissue Factor Regulates Plasminogen Binding and Activation

Zhiqiang Fan, Peter J. Larson, John Bognacki, P.N. Raghunath, John E. Tomaszewski, Alice Kuo, Gabriela Canziani, Irwin Chaiken, Douglas B. Cines, Abd Al-Roof Higazi
Journal: Blood
Blood (1998) 91 (6): 1987–1998.
https://doi.org/10.1182/blood.V91.6.1987
Published: 1998